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The map label for this gene is dapH [H]

Identifier: 226223629

GI number: 226223629

Start: 1041723

End: 1042433

Strand: Direct

Name: dapH [H]

Synonym: Lm4b_01031

Alternate gene names: 226223629

Gene position: 1041723-1042433 (Clockwise)

Preceding gene: 226223628

Following gene: 226223630

Centisome position: 35.76

GC content: 40.08

Gene sequence:

>711_bases
ATGGAACAAATGGATGCACATCAAATTATTTCTTTTATTCAAAATAGCAAGAAAGCAACACCTGTAAAAGTTTACCTTAA
AGGGGACTTAGAAAAAATTGATTTCCCTAGTGATGTTAAAACTTTCATTACTGGAAATGCGGGAACTATTTTTGGAGAAT
GGGCAGTTGTTGAGCCATTTTTAGAAGCAAATAAAGCGAATATTGAAGATTATGTTATCGAAAATGATCGTCGTAACTCG
GCTATTCCTTTGTTAGATATGAAAAATATTAACGCACGTATTGAGCCAGGCGCAGTTATTCGCGACCAAGTAACTATTGG
TGATAATGCTGTAATTATGATGGGAGCAAGCATTAATATTGGTTCTGTTATCGGTGACGGTACGATGATTGATATGAATG
TTGTTCTAGGCGGGCGCGCAACGGTTGGTAAAAATTGCCATATCGGTGCAGGTTCTGTGCTTGCTGGCGTAGTGGAACCA
CCATCCGCACAACCAGTTGTCGTAGAAGATAATGTTGTTGTAGGCGCCAATGTGGTTGTTTTAGAAGGTGTACGTATTGG
AGAAGGCGCAGTCGTAGCAGCTGGCGCAATCGTTACAAAAGACGTAGCTCCTGGAACAGTTGTGGCTGGGATTCCTGCAC
GTGAACTTAAAAAATTAGACGCAAAAACAGCTTCTAAAACTGAAATCATGCAAGAACTTCGTCAACTTTAA

Upstream 100 bases:

>100_bases
AAGTGAAGGCGTTTTTAGAAATAACAGATAAATTCCTTGAACAAGTTAAATAGCTATGGCAAAATAGAAAACAGAACGTA
TCGGAAGGGGACAAAAATTC

Downstream 100 bases:

>100_bases
AAATTAAAGGGAACTGTTTCGTCTGTTGGCGAAGCAGTCCTTTTTTAGAAGGAGAGAATCGCTGTGTTAAATGAATTTAT
TGCCATTCGACGAGAGTTAC

Product: tetrahydrodipicolinate succinylase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MEQMDAHQIISFIQNSKKATPVKVYLKGDLEKIDFPSDVKTFITGNAGTIFGEWAVVEPFLEANKANIEDYVIENDRRNS
AIPLLDMKNINARIEPGAVIRDQVTIGDNAVIMMGASINIGSVIGDGTMIDMNVVLGGRATVGKNCHIGAGSVLAGVVEP
PSAQPVVVEDNVVVGANVVVLEGVRIGEGAVVAAGAIVTKDVAPGTVVAGIPARELKKLDAKTASKTEIMQELRQL

Sequences:

>Translated_236_residues
MEQMDAHQIISFIQNSKKATPVKVYLKGDLEKIDFPSDVKTFITGNAGTIFGEWAVVEPFLEANKANIEDYVIENDRRNS
AIPLLDMKNINARIEPGAVIRDQVTIGDNAVIMMGASINIGSVIGDGTMIDMNVVLGGRATVGKNCHIGAGSVLAGVVEP
PSAQPVVVEDNVVVGANVVVLEGVRIGEGAVVAAGAIVTKDVAPGTVVAGIPARELKKLDAKTASKTEIMQELRQL
>Mature_236_residues
MEQMDAHQIISFIQNSKKATPVKVYLKGDLEKIDFPSDVKTFITGNAGTIFGEWAVVEPFLEANKANIEDYVIENDRRNS
AIPLLDMKNINARIEPGAVIRDQVTIGDNAVIMMGASINIGSVIGDGTMIDMNVVLGGRATVGKNCHIGAGSVLAGVVEP
PSAQPVVVEDNVVVGANVVVLEGVRIGEGAVVAAGAIVTKDVAPGTVVAGIPARELKKLDAKTASKTEIMQELRQL

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate [H]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786362, Length=171, Percent_Identity=32.1637426900585, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786537, Length=132, Percent_Identity=29.5454545454545, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013710
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004 [H]

Pfam domain/function: PF08503 DapD_N [H]

EC number: =2.3.1.89 [H]

Molecular weight: Translated: 24869; Mature: 24869

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQMDAHQIISFIQNSKKATPVKVYLKGDLEKIDFPSDVKTFITGNAGTIFGEWAVVEPF
CCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCEEEECHHEEHHH
LEANKANIEDYVIENDRRNSAIPLLDMKNINARIEPGAVIRDQVTIGDNAVIMMGASINI
HHCCCCCCCEEEEECCCCCCCCCEEEECCCCCEECCCCEEEEEEEECCCEEEEEECCCCC
GSVIGDGTMIDMNVVLGGRATVGKNCHIGAGSVLAGVVEPPSAQPVVVEDNVVVGANVVV
CEEECCCEEEEEEEEECCCEECCCCCCCCCCHHEEEEECCCCCCCEEEECCEEECCCEEE
LEGVRIGEGAVVAAGAIVTKDVAPGTVVAGIPARELKKLDAKTASKTEIMQELRQL
EECEEECCCCEEEECEEEECCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MEQMDAHQIISFIQNSKKATPVKVYLKGDLEKIDFPSDVKTFITGNAGTIFGEWAVVEPF
CCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCEEEECHHEEHHH
LEANKANIEDYVIENDRRNSAIPLLDMKNINARIEPGAVIRDQVTIGDNAVIMMGASINI
HHCCCCCCCEEEEECCCCCCCCCEEEECCCCCEECCCCEEEEEEEECCCEEEEEECCCCC
GSVIGDGTMIDMNVVLGGRATVGKNCHIGAGSVLAGVVEPPSAQPVVVEDNVVVGANVVV
CEEECCCEEEEEEEEECCCEECCCCCCCCCCHHEEEEECCCCCCCEEEECCEEECCCEEE
LEGVRIGEGAVVAAGAIVTKDVAPGTVVAGIPARELKKLDAKTASKTEIMQELRQL
EECEEECCCCEEEECEEEECCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]