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The map label for this gene is ykuM [H]

Identifier: 226223628

GI number: 226223628

Start: 1040797

End: 1041675

Strand: Direct

Name: ykuM [H]

Synonym: Lm4b_01030

Alternate gene names: 226223628

Gene position: 1040797-1041675 (Clockwise)

Preceding gene: 226223627

Following gene: 226223629

Centisome position: 35.73

GC content: 38.79

Gene sequence:

>879_bases
ATGATTGTAACAGAATATGAATTACTTGTTTGTTTAGCAGAAGAGCTTAATATGCGTAAAAGTGCGGAAAAACTATTTTT
AAGTCAACCGGCCTTATCGCAACGCTTACAAACGATTGAAAGTAGATGGAATACCAAAATTTTTATTCGTACACAAAAAG
GCTTACTGCTTACACCAGAAGGAGAAGCTATTGTTCGTCATGCGTCTAGTGTCATTGAACGAGAGCACACTATTCAAGAA
AAACTCGAAGCGATGGAAGGCGTTGTCCGCGGAACATTACGAATTGCTTGTGCAAGCGTAGTGGCGCAAATGTGGCTTCC
TCGGGTTCTGAAAGCATTTTCAAGAACGTACCCTAATGTGCAAATTTCACTTGTAACTGGCTGGAGCAGTGAAGTTACGC
AACAACTCGCTGCTGGAAATGTCCATATCGGCATTGTCCGTGGAAGCTCCACATGGAAAAGTGTTCAAAAACCGTTATTT
AATGACAAATTAATTTTAGTAGACACAGAAATTACCAAAATTGAAGAAGTTTTCCAAACTAATCGACCATTTATTCAATT
TCGCAGTGATTCGAATTATTACCAAGTTATTCAAGACTACTGGCAACGAAATTTCGGAAAAATGCCACGCCAAGCAATGC
TTATGGATCAGATGGAAACCTCTAGACAAATGGCCTTAAATGGTATTGGTTTTGCAATTTTACCGGAAGTGACGATGATA
GGCTACACAGATAAAATCAACAAAATTCCCTTAACGGAAAAAGATGGCTCGATTTTAAGCCGGGAAACCAACTTGCTGAC
CTATGAACAGTCACTCAGTTTACCACAAGTGAAGGCGTTTTTAGAAATAACAGATAAATTCCTTGAACAAGTTAAATAG

Upstream 100 bases:

>100_bases
GTGTTGTAGATGCTGACCACCATTTTGAAGGGATAGTAACAAGACGTGTTGTTTTAAAACAAGTCAATCGTTATATTCAT
TTGCAGGTGGAGGAAAATAG

Downstream 100 bases:

>100_bases
CTATGGCAAAATAGAAAACAGAACGTATCGGAAGGGGACAAAAATTCATGGAACAAATGGATGCACATCAAATTATTTCT
TTTATTCAAAATAGCAAGAA

Product: transcription regulator LysR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MIVTEYELLVCLAEELNMRKSAEKLFLSQPALSQRLQTIESRWNTKIFIRTQKGLLLTPEGEAIVRHASSVIEREHTIQE
KLEAMEGVVRGTLRIACASVVAQMWLPRVLKAFSRTYPNVQISLVTGWSSEVTQQLAAGNVHIGIVRGSSTWKSVQKPLF
NDKLILVDTEITKIEEVFQTNRPFIQFRSDSNYYQVIQDYWQRNFGKMPRQAMLMDQMETSRQMALNGIGFAILPEVTMI
GYTDKINKIPLTEKDGSILSRETNLLTYEQSLSLPQVKAFLEITDKFLEQVK

Sequences:

>Translated_292_residues
MIVTEYELLVCLAEELNMRKSAEKLFLSQPALSQRLQTIESRWNTKIFIRTQKGLLLTPEGEAIVRHASSVIEREHTIQE
KLEAMEGVVRGTLRIACASVVAQMWLPRVLKAFSRTYPNVQISLVTGWSSEVTQQLAAGNVHIGIVRGSSTWKSVQKPLF
NDKLILVDTEITKIEEVFQTNRPFIQFRSDSNYYQVIQDYWQRNFGKMPRQAMLMDQMETSRQMALNGIGFAILPEVTMI
GYTDKINKIPLTEKDGSILSRETNLLTYEQSLSLPQVKAFLEITDKFLEQVK
>Mature_292_residues
MIVTEYELLVCLAEELNMRKSAEKLFLSQPALSQRLQTIESRWNTKIFIRTQKGLLLTPEGEAIVRHASSVIEREHTIQE
KLEAMEGVVRGTLRIACASVVAQMWLPRVLKAFSRTYPNVQISLVTGWSSEVTQQLAAGNVHIGIVRGSSTWKSVQKPLF
NDKLILVDTEITKIEEVFQTNRPFIQFRSDSNYYQVIQDYWQRNFGKMPRQAMLMDQMETSRQMALNGIGFAILPEVTMI
GYTDKINKIPLTEKDGSILSRETNLLTYEQSLSLPQVKAFLEITDKFLEQVK

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787806, Length=294, Percent_Identity=21.4285714285714, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787601, Length=137, Percent_Identity=27.7372262773723, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787530, Length=133, Percent_Identity=30.0751879699248, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790399, Length=171, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790208, Length=293, Percent_Identity=21.8430034129693, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=22.4913494809689, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786401, Length=158, Percent_Identity=30.379746835443, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788296, Length=199, Percent_Identity=27.1356783919598, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87081904, Length=178, Percent_Identity=26.9662921348315, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787879, Length=264, Percent_Identity=25, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787128, Length=147, Percent_Identity=24.4897959183673, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788887, Length=248, Percent_Identity=22.9838709677419, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33434; Mature: 33434

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVTEYELLVCLAEELNMRKSAEKLFLSQPALSQRLQTIESRWNTKIFIRTQKGLLLTPE
CEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCC
GEAIVRHASSVIEREHTIQEKLEAMEGVVRGTLRIACASVVAQMWLPRVLKAFSRTYPNV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
QISLVTGWSSEVTQQLAAGNVHIGIVRGSSTWKSVQKPLFNDKLILVDTEITKIEEVFQT
EEEEEECCCHHHHHHHHCCCEEEEEEECCCHHHHHHCCCCCCCEEEEECHHHHHHHHHHC
NRPFIQFRSDSNYYQVIQDYWQRNFGKMPRQAMLMDQMETSRQMALNGIGFAILPEVTMI
CCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEE
GYTDKINKIPLTEKDGSILSRETNLLTYEQSLSLPQVKAFLEITDKFLEQVK
ECCCCCCCCCCCCCCCCHHHCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIVTEYELLVCLAEELNMRKSAEKLFLSQPALSQRLQTIESRWNTKIFIRTQKGLLLTPE
CEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCC
GEAIVRHASSVIEREHTIQEKLEAMEGVVRGTLRIACASVVAQMWLPRVLKAFSRTYPNV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
QISLVTGWSSEVTQQLAAGNVHIGIVRGSSTWKSVQKPLFNDKLILVDTEITKIEEVFQT
EEEEEECCCHHHHHHHHCCCEEEEEEECCCHHHHHHCCCCCCCEEEEECHHHHHHHHHHC
NRPFIQFRSDSNYYQVIQDYWQRNFGKMPRQAMLMDQMETSRQMALNGIGFAILPEVTMI
CCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEE
GYTDKINKIPLTEKDGSILSRETNLLTYEQSLSLPQVKAFLEITDKFLEQVK
ECCCCCCCCCCCCCCCCHHHCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]