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The map label for this gene is clpE

Identifier: 226223615

GI number: 226223615

Start: 1027932

End: 1030100

Strand: Reverse

Name: clpE

Synonym: Lm4b_01017

Alternate gene names: 226223615

Gene position: 1030100-1027932 (Counterclockwise)

Preceding gene: 226223616

Following gene: 226223613

Centisome position: 35.37

GC content: 39.79

Gene sequence:

>2169_bases
ATGAACTGTGAAAAATGTAATCAAAATCCAGCAACAATCCAACTATATATGAATATTAATGGCAAGCGTGTAGAAATGCC
GCTTTGTGCCTCTTGTTATGCAGAAGTTAGAAATCAAGCAAACTTTGGGGCGAATGAGTTCCCAGGAGCAAGCGGTTCCC
CGTTTGACGATATTTTCCGTCAATTGAGTGGTGCTGCTAGTCAAGCAAACCGTGAACAAAGAAGCCAAGCACAAGTACAA
ACACAAACTGCTGGTGGCGGCAATGGTTTACTAGATGAATTTGGAACAAACTTAACAGATATGGCGAAAAATGAGCAACT
CGACCCTGTCATCGGTCGTGACAAAGAAATTAAACGCGTCATTGAAATATTAAACCGCCGTAATAAAAATAATCCAGTCT
TAATTGGTGAACCAGGTGTTGGTAAAACAGCTGTCGTCGAAGGACTTGCAAATGCAATTGTCGCAGGAGACGTTCCAAGC
AAACTAATGAACAAAGAAGTTATCTTATTAGATGTCGCTTCGCTTGTTTCTGGAACAGGTATCCGCGGTCAATTTGAAGA
ACGTATGAAACAACTGATTAAAGAACTACAAGAACGTAAAAACACGATTCTATTTATTGATGAAGTGCATACGATTGTTG
GGGCAGGTTCCGCAGAAGGCTCGATGGATGCAGGAAACATTCTAAAACCAGCTCTAGCTCGTGGCGATTTACAAATGATT
GGTGCTACTACACTAAAAGAATACCGCACAATCGAAAAAGATGCCGCACTTGAGCGCCGTTTCCAACCAGTAACTGTAAG
CGAACCATCCACAAAAGAAACGCTAACTATTTTAAATGGTTTAAAACCAAAATATGAAGATTTCCATGAAGTAGTTTATT
CACCAGAAGCACTAACAGCAGCAGTTGAATTAAGCGCTCGTTATATCCAAGATCGTCATTTGCCAGATAAAGCAATTGAT
TTAATGGATGAAGTTGGCTCGAAATATAATCTATCCATTGAAAAACTGGACGAAAATACGGTGAGCGAACGTGTTGCCCG
TTTAGAAGATGAAAAAAATCAAGCTCTTCAAATGGAAGACTACGAAAAGGCAGCCAAAGTTCGTGATGAAATTACTCGCT
TAGAAGAAAATAAAACAAATAACTCCTTCTCAGAGCGTCCAGTCATCCAAGCATCCGACATCCAAGCAATTATTGAAGAA
AAAACAGGTATTCCAGTAGGACGCTTACAAGAAGACGAGCAATCTAAAATGAAGAACTTAGAAAGTAACTTAACTGGAAA
AGTCATTGGTCAAGAAGATGCTGTAAGAAAAGTAGCTAAAGCAATTCGTCGTAGCCGTGTTGGCCTCAAATCAAAAAATC
GCCCAATTGGTTCCTTCCTATTTGTTGGACCAACTGGTGTCGGAAAAACAGAACTTGGACGCACGCTAGCTCGTGAATTG
TTTGGTACTAGTGAAGCGATGATTCGTTTAGACATGAGTGAATTCATGGAAAAACACAGCGTCTCTAAATTAATCGGTTC
CCCTCCTGGCTATGTTGGTCACGAAGAAGCTGGACAATTAACAGAAAAAGTTCGTCGCAATCCGTATAGCATCATTTTGT
TAGACGAAATCGAAAAAGCACATCCAGACGTTCAACATATGTTCCTGCAAATTTTAGAAGACGGTCGACTAACTGATTCA
CAAGGACGTACAGTGAGCTTTAAAGATACAGTCATCATTATGACAAGTAACGCTGGCGCAACTGACACAGAAGCTTCGGT
CGGCTTTAATACAACAACCGAAGCAAAACTTGAAAAAGGTTCTGACATCTTAGCAAAATTAGGCGCATACTTCAAACCAG
AATTCTTAAACCGTCTAGACAGCGTCATTGAATTTAAATCCCTAGAAAAAGACGATTTAGTACAAATCATCGACTTAATG
CTCGTTGATTTAAATGAAATGCTCGCTCAAGAAGATGTGACAATCGATGTTTCTAAAGAAGTAAAAGAACATTTGATTGA
CCTTGGTTATGACCCTAAATTCGGAGCACGTCCACTACGCCGGACTATCCAAGAACACCTAGAAGATGCGATTGCCGACA
GTCTAATTGAACAACCAGAAGCAAAACATCTTGTTGCAACCCTTAACGAAAATAAAGAAATTACTATAACAGAACAAGTA
ACAGTGTAA

Upstream 100 bases:

>100_bases
TTGAAAGTCAAAATAGGTCAGTATATAATAAAGTCATAAGGTCAAAGATAGTCAAAGTCAAGACCTTTCATTTCTCATTT
TTAAAAGGAGGAAATTATAT

Downstream 100 bases:

>100_bases
TAAAAAAGGCTTGAGTTAACTTAAACTCAAGCCTTTTTCTAATGCAAGTAAATATTGTTTCTTATCTACATCCGCCCCGT
TATAGCCCCCAAGTTCTCCA

Product: ATP-dependent protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 722; Mature: 722

Protein sequence:

>722_residues
MNCEKCNQNPATIQLYMNINGKRVEMPLCASCYAEVRNQANFGANEFPGASGSPFDDIFRQLSGAASQANREQRSQAQVQ
TQTAGGGNGLLDEFGTNLTDMAKNEQLDPVIGRDKEIKRVIEILNRRNKNNPVLIGEPGVGKTAVVEGLANAIVAGDVPS
KLMNKEVILLDVASLVSGTGIRGQFEERMKQLIKELQERKNTILFIDEVHTIVGAGSAEGSMDAGNILKPALARGDLQMI
GATTLKEYRTIEKDAALERRFQPVTVSEPSTKETLTILNGLKPKYEDFHEVVYSPEALTAAVELSARYIQDRHLPDKAID
LMDEVGSKYNLSIEKLDENTVSERVARLEDEKNQALQMEDYEKAAKVRDEITRLEENKTNNSFSERPVIQASDIQAIIEE
KTGIPVGRLQEDEQSKMKNLESNLTGKVIGQEDAVRKVAKAIRRSRVGLKSKNRPIGSFLFVGPTGVGKTELGRTLAREL
FGTSEAMIRLDMSEFMEKHSVSKLIGSPPGYVGHEEAGQLTEKVRRNPYSIILLDEIEKAHPDVQHMFLQILEDGRLTDS
QGRTVSFKDTVIIMTSNAGATDTEASVGFNTTTEAKLEKGSDILAKLGAYFKPEFLNRLDSVIEFKSLEKDDLVQIIDLM
LVDLNEMLAQEDVTIDVSKEVKEHLIDLGYDPKFGARPLRRTIQEHLEDAIADSLIEQPEAKHLVATLNENKEITITEQV
TV

Sequences:

>Translated_722_residues
MNCEKCNQNPATIQLYMNINGKRVEMPLCASCYAEVRNQANFGANEFPGASGSPFDDIFRQLSGAASQANREQRSQAQVQ
TQTAGGGNGLLDEFGTNLTDMAKNEQLDPVIGRDKEIKRVIEILNRRNKNNPVLIGEPGVGKTAVVEGLANAIVAGDVPS
KLMNKEVILLDVASLVSGTGIRGQFEERMKQLIKELQERKNTILFIDEVHTIVGAGSAEGSMDAGNILKPALARGDLQMI
GATTLKEYRTIEKDAALERRFQPVTVSEPSTKETLTILNGLKPKYEDFHEVVYSPEALTAAVELSARYIQDRHLPDKAID
LMDEVGSKYNLSIEKLDENTVSERVARLEDEKNQALQMEDYEKAAKVRDEITRLEENKTNNSFSERPVIQASDIQAIIEE
KTGIPVGRLQEDEQSKMKNLESNLTGKVIGQEDAVRKVAKAIRRSRVGLKSKNRPIGSFLFVGPTGVGKTELGRTLAREL
FGTSEAMIRLDMSEFMEKHSVSKLIGSPPGYVGHEEAGQLTEKVRRNPYSIILLDEIEKAHPDVQHMFLQILEDGRLTDS
QGRTVSFKDTVIIMTSNAGATDTEASVGFNTTTEAKLEKGSDILAKLGAYFKPEFLNRLDSVIEFKSLEKDDLVQIIDLM
LVDLNEMLAQEDVTIDVSKEVKEHLIDLGYDPKFGARPLRRTIQEHLEDAIADSLIEQPEAKHLVATLNENKEITITEQV
TV
>Mature_722_residues
MNCEKCNQNPATIQLYMNINGKRVEMPLCASCYAEVRNQANFGANEFPGASGSPFDDIFRQLSGAASQANREQRSQAQVQ
TQTAGGGNGLLDEFGTNLTDMAKNEQLDPVIGRDKEIKRVIEILNRRNKNNPVLIGEPGVGKTAVVEGLANAIVAGDVPS
KLMNKEVILLDVASLVSGTGIRGQFEERMKQLIKELQERKNTILFIDEVHTIVGAGSAEGSMDAGNILKPALARGDLQMI
GATTLKEYRTIEKDAALERRFQPVTVSEPSTKETLTILNGLKPKYEDFHEVVYSPEALTAAVELSARYIQDRHLPDKAID
LMDEVGSKYNLSIEKLDENTVSERVARLEDEKNQALQMEDYEKAAKVRDEITRLEENKTNNSFSERPVIQASDIQAIIEE
KTGIPVGRLQEDEQSKMKNLESNLTGKVIGQEDAVRKVAKAIRRSRVGLKSKNRPIGSFLFVGPTGVGKTELGRTLAREL
FGTSEAMIRLDMSEFMEKHSVSKLIGSPPGYVGHEEAGQLTEKVRRNPYSIILLDEIEKAHPDVQHMFLQILEDGRLTDS
QGRTVSFKDTVIIMTSNAGATDTEASVGFNTTTEAKLEKGSDILAKLGAYFKPEFLNRLDSVIEFKSLEKDDLVQIIDLM
LVDLNEMLAQEDVTIDVSKEVKEHLIDLGYDPKFGARPLRRTIQEHLEDAIADSLIEQPEAKHLVATLNENKEITITEQV
TV

Specific function: Could be necessary for degrading proteins generated by certain types of stress [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=301, Percent_Identity=37.2093023255814, Blast_Score=194, Evalue=4e-49,
Organism=Escherichia coli, GI1787109, Length=639, Percent_Identity=41.9405320813771, Blast_Score=517, Evalue=1e-147,
Organism=Escherichia coli, GI1788943, Length=335, Percent_Identity=48.0597014925373, Blast_Score=317, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6320464, Length=683, Percent_Identity=42.4597364568082, Blast_Score=525, Evalue=1e-149,
Organism=Saccharomyces cerevisiae, GI6323002, Length=331, Percent_Identity=38.6706948640483, Blast_Score=242, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR001943
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 80008; Mature: 80008

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCEKCNQNPATIQLYMNINGKRVEMPLCASCYAEVRNQANFGANEFPGASGSPFDDIFR
CCCCCCCCCCCEEEEEEECCCCEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
QLSGAASQANREQRSQAQVQTQTAGGGNGLLDEFGTNLTDMAKNEQLDPVIGRDKEIKRV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHCCCCCCCCCCCCHHHHHH
IEILNRRNKNNPVLIGEPGVGKTAVVEGLANAIVAGDVPSKLMNKEVILLDVASLVSGTG
HHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCEEEEEHHHHHCCCC
IRGQFEERMKQLIKELQERKNTILFIDEVHTIVGAGSAEGSMDAGNILKPALARGDLQMI
CCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHH
GATTLKEYRTIEKDAALERRFQPVTVSEPSTKETLTILNGLKPKYEDFHEVVYSPEALTA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHH
AVELSARYIQDRHLPDKAIDLMDEVGSKYNLSIEKLDENTVSERVARLEDEKNQALQMED
HHHHHHHHHHHCCCCHHHHHHHHHCCCCEECCHHHHCHHHHHHHHHHHHHHHHCCCCHHH
YEKAAKVRDEITRLEENKTNNSFSERPVIQASDIQAIIEEKTGIPVGRLQEDEQSKMKNL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
ESNLTGKVIGQEDAVRKVAKAIRRSRVGLKSKNRPIGSFLFVGPTGVGKTELGRTLAREL
HHCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
FGTSEAMIRLDMSEFMEKHSVSKLIGSPPGYVGHEEAGQLTEKVRRNPYSIILLDEIEKA
HCCCHHHEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHH
HPDVQHMFLQILEDGRLTDSQGRTVSFKDTVIIMTSNAGATDTEASVGFNTTTEAKLEKG
CCCHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCHHHHHCC
SDILAKLGAYFKPEFLNRLDSVIEFKSLEKDDLVQIIDLMLVDLNEMLAQEDVTIDVSKE
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHH
VKEHLIDLGYDPKFGARPLRRTIQEHLEDAIADSLIEQPEAKHLVATLNENKEITITEQV
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEECCCCEEEEEEEE
TV
CC
>Mature Secondary Structure
MNCEKCNQNPATIQLYMNINGKRVEMPLCASCYAEVRNQANFGANEFPGASGSPFDDIFR
CCCCCCCCCCCEEEEEEECCCCEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
QLSGAASQANREQRSQAQVQTQTAGGGNGLLDEFGTNLTDMAKNEQLDPVIGRDKEIKRV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHCCCCCCCCCCCCHHHHHH
IEILNRRNKNNPVLIGEPGVGKTAVVEGLANAIVAGDVPSKLMNKEVILLDVASLVSGTG
HHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCEEEEEHHHHHCCCC
IRGQFEERMKQLIKELQERKNTILFIDEVHTIVGAGSAEGSMDAGNILKPALARGDLQMI
CCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHH
GATTLKEYRTIEKDAALERRFQPVTVSEPSTKETLTILNGLKPKYEDFHEVVYSPEALTA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHH
AVELSARYIQDRHLPDKAIDLMDEVGSKYNLSIEKLDENTVSERVARLEDEKNQALQMED
HHHHHHHHHHHCCCCHHHHHHHHHCCCCEECCHHHHCHHHHHHHHHHHHHHHHCCCCHHH
YEKAAKVRDEITRLEENKTNNSFSERPVIQASDIQAIIEEKTGIPVGRLQEDEQSKMKNL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
ESNLTGKVIGQEDAVRKVAKAIRRSRVGLKSKNRPIGSFLFVGPTGVGKTELGRTLAREL
HHCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
FGTSEAMIRLDMSEFMEKHSVSKLIGSPPGYVGHEEAGQLTEKVRRNPYSIILLDEIEKA
HCCCHHHEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHH
HPDVQHMFLQILEDGRLTDSQGRTVSFKDTVIIMTSNAGATDTEASVGFNTTTEAKLEKG
CCCHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCHHHHHCC
SDILAKLGAYFKPEFLNRLDSVIEFKSLEKDDLVQIIDLMLVDLNEMLAQEDVTIDVSKE
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHH
VKEHLIDLGYDPKFGARPLRRTIQEHLEDAIADSLIEQPEAKHLVATLNENKEITITEQV
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEECCCCEEEEEEEE
TV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]