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The map label for this gene is rsbR

Identifier: 226223508

GI number: 226223508

Start: 927465

End: 928301

Strand: Direct

Name: rsbR

Synonym: Lm4b_00907

Alternate gene names: 226223508

Gene position: 927465-928301 (Clockwise)

Preceding gene: 226223507

Following gene: 226223509

Centisome position: 31.84

GC content: 38.11

Gene sequence:

>837_bases
ATGTATAAAGATTTTGCAAACTTCATCCGTACAAATAAAGCAGACTTACTAAACAACTGGATGAATGAAATGGAAAAACA
ATCAGATCAGCTAATCAACGACATTGCAAAAGAAGCAATGTACGAAGAAACTAGCAAAGAATTTGTGGATTTAATTGTTT
CGAATGTTACCGAAAACGGCTCTAAATTCAACGAAAAACTAGATGATTTTGCAGAGAAAGTGGTCCACCTAGGTTGGCCG
ATTCATTTTGTTACCACTGGCCTACGTGTTTTTGGGCTTTTAGTATATACAGCAATGAGAGATGAAGATTTATTTTTAAA
GAGAGAAGAAAAACCTGAAGATGATGCCTATTATCGCTTTGAAACATGGCTTTCCTCCATGTATAACAAAGTGGTCACAG
CCTACGCGGATACGTGGGAAAAGACAGTTTCTATCCAAAAAAGTGCACTACAGGAATTATCGGCACCACTTTTGCCAATA
TTTGAAAAAATTTCTGTAATGCCGTTAATTGGGACGATTGACACGGAAAGAGCCAAGTTAATCATAGAAAATTTATTAAT
AGGTGTTGTAAAAAATCGGTCAGAAGTGGTTTTGATTGATATTACGGGAGTTCCTGTTGTTGATACAATGGTTGCGCACC
ATATTATTCAAGCGTCCGAAGCGGTTAGACTTGTCGGCTGTCAGGCGATGCTTGTAGGTATTAGACCAGAAATCGCGCAA
ACAATCGTTAACTTAGGAATTGAATTAGATCAAATTATCACGACCAACACAATGAAAAAAGGCATGGAGCGTGCGCTAGC
CTTGACGAACAGAGAGATAGTAGAAAAAGAGGGGTGA

Upstream 100 bases:

>100_bases
CTAAATTTGTTTCTAATGTCTTTTTTAAAAGGCAGTTAAGCAAACCGCACAATAAGAGAGAAAATTTTGTTAATAGTGGA
GAAAGGTTGGAAAATAACTG

Downstream 100 bases:

>100_bases
ATACTGTGGGGATACCAATCTTAAAGTTAGGTGAATGTTTATTAATTTCTATCCAGAGTGAATTAGATGATCATACTGCG
GTAGAATTCCAGGAAGATTT

Product: positive regulator of sigma-B activity

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MYKDFANFIRTNKADLLNNWMNEMEKQSDQLINDIAKEAMYEETSKEFVDLIVSNVTENGSKFNEKLDDFAEKVVHLGWP
IHFVTTGLRVFGLLVYTAMRDEDLFLKREEKPEDDAYYRFETWLSSMYNKVVTAYADTWEKTVSIQKSALQELSAPLLPI
FEKISVMPLIGTIDTERAKLIIENLLIGVVKNRSEVVLIDITGVPVVDTMVAHHIIQASEAVRLVGCQAMLVGIRPEIAQ
TIVNLGIELDQIITTNTMKKGMERALALTNREIVEKEG

Sequences:

>Translated_278_residues
MYKDFANFIRTNKADLLNNWMNEMEKQSDQLINDIAKEAMYEETSKEFVDLIVSNVTENGSKFNEKLDDFAEKVVHLGWP
IHFVTTGLRVFGLLVYTAMRDEDLFLKREEKPEDDAYYRFETWLSSMYNKVVTAYADTWEKTVSIQKSALQELSAPLLPI
FEKISVMPLIGTIDTERAKLIIENLLIGVVKNRSEVVLIDITGVPVVDTMVAHHIIQASEAVRLVGCQAMLVGIRPEIAQ
TIVNLGIELDQIITTNTMKKGMERALALTNREIVEKEG
>Mature_278_residues
MYKDFANFIRTNKADLLNNWMNEMEKQSDQLINDIAKEAMYEETSKEFVDLIVSNVTENGSKFNEKLDDFAEKVVHLGWP
IHFVTTGLRVFGLLVYTAMRDEDLFLKREEKPEDDAYYRFETWLSSMYNKVVTAYADTWEKTVSIQKSALQELSAPLLPI
FEKISVMPLIGTIDTERAKLIIENLLIGVVKNRSEVVLIDITGVPVVDTMVAHHIIQASEAVRLVGCQAMLVGIRPEIAQ
TIVNLGIELDQIITTNTMKKGMERALALTNREIVEKEG

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 31620; Mature: 31620

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKDFANFIRTNKADLLNNWMNEMEKQSDQLINDIAKEAMYEETSKEFVDLIVSNVTENG
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SKFNEKLDDFAEKVVHLGWPIHFVTTGLRVFGLLVYTAMRDEDLFLKREEKPEDDAYYRF
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHH
ETWLSSMYNKVVTAYADTWEKTVSIQKSALQELSAPLLPIFEKISVMPLIGTIDTERAKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHH
IIENLLIGVVKNRSEVVLIDITGVPVVDTMVAHHIIQASEAVRLVGCQAMLVGIRPEIAQ
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
TIVNLGIELDQIITTNTMKKGMERALALTNREIVEKEG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYKDFANFIRTNKADLLNNWMNEMEKQSDQLINDIAKEAMYEETSKEFVDLIVSNVTENG
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SKFNEKLDDFAEKVVHLGWPIHFVTTGLRVFGLLVYTAMRDEDLFLKREEKPEDDAYYRF
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHH
ETWLSSMYNKVVTAYADTWEKTVSIQKSALQELSAPLLPIFEKISVMPLIGTIDTERAKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHH
IIENLLIGVVKNRSEVVLIDITGVPVVDTMVAHHIIQASEAVRLVGCQAMLVGIRPEIAQ
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
TIVNLGIELDQIITTNTMKKGMERALALTNREIVEKEG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]