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The map label for this gene is ndoA [H]

Identifier: 226223507

GI number: 226223507

Start: 926867

End: 927214

Strand: Direct

Name: ndoA [H]

Synonym: Lm4b_00906

Alternate gene names: 226223507

Gene position: 926867-927214 (Clockwise)

Preceding gene: 226223506

Following gene: 226223508

Centisome position: 31.82

GC content: 41.95

Gene sequence:

>348_bases
CTGATGGTGAAGCGTGGTGACGTATACTACGCGGACCTTTCCCCCGTGGTCGGAAGCGAGCAAGGGGGAATACGGCCTGT
TCTCATCATTCAAAATGATATTGGTAATAGATTCAGTCCAACTGTGATTGTGGCAGCAATAACTGCAAAAATTCAAAAAG
CAAAATTGCCAACACACGTGGAAGCTACTCGTAAAGATGGCTTTGAGAGAGATTCTGTCATTCTTTTAGAACAAATTAGA
ACGATTGACAAACAGCGCCTGACAGACAAAATTACACATTTGGACGAAGATTTAATGGCCAAGGTAAACAAGGCACTTGA
AGTCAGTCTAGGAGTAGTAGAATTTTAA

Upstream 100 bases:

>100_bases
TGCAGAAATGGCGACAATTAATTTCGCTATCGCATGCGAGTGTACCCATGTCGAAGCAGAAGCAGAAGACAGGAATATTA
GTATTTTAGGAGGTTAATGG

Downstream 100 bases:

>100_bases
TCCATCCTAAAAAATAACATACAATGATGAATGCAGGACAAAAGGGTCTGACGTAAAATAATAAGTTTAATACATAATGA
AATAATTAACTGCTCTGAAG

Product: YdcE protein

Products: NA

Alternate protein names: Endoribonuclease EndoA; Toxin EndoA [H]

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MMVKRGDVYYADLSPVVGSEQGGIRPVLIIQNDIGNRFSPTVIVAAITAKIQKAKLPTHVEATRKDGFERDSVILLEQIR
TIDKQRLTDKITHLDEDLMAKVNKALEVSLGVVEF

Sequences:

>Translated_115_residues
MMVKRGDVYYADLSPVVGSEQGGIRPVLIIQNDIGNRFSPTVIVAAITAKIQKAKLPTHVEATRKDGFERDSVILLEQIR
TIDKQRLTDKITHLDEDLMAKVNKALEVSLGVVEF
>Mature_115_residues
MMVKRGDVYYADLSPVVGSEQGGIRPVLIIQNDIGNRFSPTVIVAAITAKIQKAKLPTHVEATRKDGFERDSVILLEQIR
TIDKQRLTDKITHLDEDLMAKVNKALEVSLGVVEF

Specific function: Part of a toxin-antitoxin (TA) module. Has specificity for UAC sequences, yielding cleavage products with 3' phosphate and 5' hydroxyl groups. Overexpression is toxic for cell growth, probably by inhibiting protein synthesis through the cleavage of single

COG id: COG2337

COG function: function code T; Growth inhibitor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PemK/MazF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003477
- InterPro:   IPR011067 [H]

Pfam domain/function: PF02452 PemK [H]

EC number: NA

Molecular weight: Translated: 12788; Mature: 12788

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVKRGDVYYADLSPVVGSEQGGIRPVLIIQNDIGNRFSPTVIVAAITAKIQKAKLPTHV
CCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCC
EATRKDGFERDSVILLEQIRTIDKQRLTDKITHLDEDLMAKVNKALEVSLGVVEF
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEECC
>Mature Secondary Structure
MMVKRGDVYYADLSPVVGSEQGGIRPVLIIQNDIGNRFSPTVIVAAITAKIQKAKLPTHV
CCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCC
EATRKDGFERDSVILLEQIRTIDKQRLTDKITHLDEDLMAKVNKALEVSLGVVEF
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]