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The map label for this gene is dal

Identifier: 226223505

GI number: 226223505

Start: 925273

End: 926379

Strand: Direct

Name: dal

Synonym: Lm4b_00904

Alternate gene names: 226223505

Gene position: 925273-926379 (Clockwise)

Preceding gene: 226223504

Following gene: 226223506

Centisome position: 31.77

GC content: 42.01

Gene sequence:

>1107_bases
ATGGTGACAGGCTGGCATCGTCCTACATGGATTGAGATAGACCGCGCAGCAATTCGCGAAAATATAAAAAATGAACAAAA
TAAACTTCCAGAAAATGTGGATTTATGGGCAGTAGTCAAAGCTAATGCATATGGTCACGGAATTATCGAAGTTGCTAGAA
CAGCGAAAGAAGCTGGAGCAAAAGGTTTCTGTGTTGCCATTTTAGATGAGGCGTTGGCTCTTAGAGAAGCTGGGTTTCAA
GATGACTTTATTCTTGTACTTGGCGCAACTAGAAAAGAAGATGCAAATTTAGCGGCCAAAAACCACATTTCCCTCACTGT
TTTTAGAGAGGACTGGCTAGAGGACCTAACCTTAGAAGCGCCACTTCGCATTCATTTAAAAGTAGATAGCGGTATGGGGC
GTCTTGGGATTCGTACAACCGACGAAGCAAGGCGAATCGAAACGACAATTGCTAAAGACAATCAACTACAACTAGAAGGT
ATCTACACGCATTTTGCGACAGCCGACCAACTTGAAACTAGTTATTTCGAACAACAATTAGCTAAGTTCCAAACCATTTT
AACGAGTTTAAAAAATCGCCCAACGTATGTTCATACAGCCAATTCAGCTGCTTCATTATTACAGCCACAAATCGGGTTTG
ATGCGATTCGCTTTGGTATATCGATGTACGGGTTAACCCCTTCCACCGAAATCAAAACTAGCTTACCATTTGAGCTTAAA
CCAGCCCTTGCACTCTATACCGAAATGGTTCATGTGAAAGAACTCGCACCAGGTGATAGTGTTAGCTACGGAGCAACCTA
CACTGCAACAGAACGAGAATGGGTTGCAACGTTACCGATTGGCTATGCAGATGGGTTGATTCGTCATTACAGCGGATTTC
ATGTTTTAGTAGACGGGGAACTAGCCCCAATTATAGGACGCGTTTGTATGGATCAAACCATCATAAAACTACCGCGCGAA
TTTCAAACTGGTTCAAAAGTAACGATAATTGGCACGGACCATGGAAACACGATAACAGCAGATGATGCCGCTCACTATTT
AGATACAATAAATTATGAGGTTACTTGTCTGTTAAATGAGCGTATACCTAGAAAATACATCCATTAG

Upstream 100 bases:

>100_bases
AGTCAAATCAGGTGAAAACGTTTTTGTGAGCATTACCCACACAGCTAGATCAGCCGCAGCTCAAGTGATAATTGAAATTT
AGAAAGGAAAGTGAACAATC

Downstream 100 bases:

>100_bases
AAGGTAATATTCGTGCTTTTTTTAGAAGAAGCGTTTATAATCTAACATATGAAACTTTATAGCTATATATAGGACTTAAG
AGAGTATATCAGCTAGAACT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MVTGWHRPTWIEIDRAAIRENIKNEQNKLPENVDLWAVVKANAYGHGIIEVARTAKEAGAKGFCVAILDEALALREAGFQ
DDFILVLGATRKEDANLAAKNHISLTVFREDWLEDLTLEAPLRIHLKVDSGMGRLGIRTTDEARRIETTIAKDNQLQLEG
IYTHFATADQLETSYFEQQLAKFQTILTSLKNRPTYVHTANSAASLLQPQIGFDAIRFGISMYGLTPSTEIKTSLPFELK
PALALYTEMVHVKELAPGDSVSYGATYTATEREWVATLPIGYADGLIRHYSGFHVLVDGELAPIIGRVCMDQTIIKLPRE
FQTGSKVTIIGTDHGNTITADDAAHYLDTINYEVTCLLNERIPRKYIH

Sequences:

>Translated_368_residues
MVTGWHRPTWIEIDRAAIRENIKNEQNKLPENVDLWAVVKANAYGHGIIEVARTAKEAGAKGFCVAILDEALALREAGFQ
DDFILVLGATRKEDANLAAKNHISLTVFREDWLEDLTLEAPLRIHLKVDSGMGRLGIRTTDEARRIETTIAKDNQLQLEG
IYTHFATADQLETSYFEQQLAKFQTILTSLKNRPTYVHTANSAASLLQPQIGFDAIRFGISMYGLTPSTEIKTSLPFELK
PALALYTEMVHVKELAPGDSVSYGATYTATEREWVATLPIGYADGLIRHYSGFHVLVDGELAPIIGRVCMDQTIIKLPRE
FQTGSKVTIIGTDHGNTITADDAAHYLDTINYEVTCLLNERIPRKYIH
>Mature_368_residues
MVTGWHRPTWIEIDRAAIRENIKNEQNKLPENVDLWAVVKANAYGHGIIEVARTAKEAGAKGFCVAILDEALALREAGFQ
DDFILVLGATRKEDANLAAKNHISLTVFREDWLEDLTLEAPLRIHLKVDSGMGRLGIRTTDEARRIETTIAKDNQLQLEG
IYTHFATADQLETSYFEQQLAKFQTILTSLKNRPTYVHTANSAASLLQPQIGFDAIRFGISMYGLTPSTEIKTSLPFELK
PALALYTEMVHVKELAPGDSVSYGATYTATEREWVATLPIGYADGLIRHYSGFHVLVDGELAPIIGRVCMDQTIIKLPRE
FQTGSKVTIIGTDHGNTITADDAAHYLDTINYEVTCLLNERIPRKYIH

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1790487, Length=361, Percent_Identity=33.2409972299169, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1787439, Length=366, Percent_Identity=32.7868852459016, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_LISMC (C1L1F6)

Other databases:

- EMBL:   FM242711
- RefSeq:   YP_002757612.1
- ProteinModelPortal:   C1L1F6
- SMR:   C1L1F6
- GeneID:   7704489
- GenomeReviews:   FM242711_GR
- KEGG:   lmc:Lm4b_00904
- OMA:   TRKEDAN
- ProtClustDB:   CLSK564147
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 41054; Mature: 41054

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 40-40 ACT_SITE 263-263

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTGWHRPTWIEIDRAAIRENIKNEQNKLPENVDLWAVVKANAYGHGIIEVARTAKEAGA
CCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCC
KGFCVAILDEALALREAGFQDDFILVLGATRKEDANLAAKNHISLTVFREDWLEDLTLEA
CCEEHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEECCCEEEEEEHHHHHHHCEECC
PLRIHLKVDSGMGRLGIRTTDEARRIETTIAKDNQLQLEGIYTHFATADQLETSYFEQQL
CEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEHHCCHHHHHHHHHHHHH
AKFQTILTSLKNRPTYVHTANSAASLLQPQIGFDAIRFGISMYGLTPSTEIKTSLPFELK
HHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCHHHHHHHHEEECCCCCCCCCCCCCCCCC
PALALYTEMVHVKELAPGDSVSYGATYTATEREWVATLPIGYADGLIRHYSGFHVLVDGE
HHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHCCCCEEEECCC
LAPIIGRVCMDQTIIKLPREFQTGSKVTIIGTDHGNTITADDAAHYLDTINYEVTCLLNE
HHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCEEECCHHHHHHHCCCEEEEEEECC
RIPRKYIH
CCCHHHCC
>Mature Secondary Structure
MVTGWHRPTWIEIDRAAIRENIKNEQNKLPENVDLWAVVKANAYGHGIIEVARTAKEAGA
CCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCC
KGFCVAILDEALALREAGFQDDFILVLGATRKEDANLAAKNHISLTVFREDWLEDLTLEA
CCEEHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEECCCEEEEEEHHHHHHHCEECC
PLRIHLKVDSGMGRLGIRTTDEARRIETTIAKDNQLQLEGIYTHFATADQLETSYFEQQL
CEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEHHCCHHHHHHHHHHHHH
AKFQTILTSLKNRPTYVHTANSAASLLQPQIGFDAIRFGISMYGLTPSTEIKTSLPFELK
HHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCHHHHHHHHEEECCCCCCCCCCCCCCCCC
PALALYTEMVHVKELAPGDSVSYGATYTATEREWVATLPIGYADGLIRHYSGFHVLVDGE
HHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHCCCCEEEECCC
LAPIIGRVCMDQTIIKLPREFQTGSKVTIIGTDHGNTITADDAAHYLDTINYEVTCLLNE
HHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCCCCEEECCHHHHHHHCCCEEEEEEECC
RIPRKYIH
CCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA