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The map label for this gene is acpS

Identifier: 226223504

GI number: 226223504

Start: 924898

End: 925254

Strand: Direct

Name: acpS

Synonym: Lm4b_00903

Alternate gene names: 226223504

Gene position: 924898-925254 (Clockwise)

Preceding gene: 226223503

Following gene: 226223505

Centisome position: 31.75

GC content: 36.97

Gene sequence:

>357_bases
ATGATTAAAGGAATCGGACTAGATATGATTGATTTAGAACGTGTAAAACAAGTCGTGGAAAAGAATCCACGCTTTATCGA
ACGTGTTTTAACAGAAAAAGAAATTAAGCAATTTGAAAAATACGAAGGTAATCGCAAAATCGAATTTTTAGCTGGGCGTT
TTGCAGCAAAAGAAGCATATGCTAAGGCGAATGGAACTGGTTTTGGCAAACATTTAAGTTTTACGGATGTAGAAATTTTG
CAAGTAGAAGATGGGCGACCCCATGTTACTTTACCAGTCAAATCAGGTGAAAACGTTTTTGTGAGCATTACCCACACAGC
TAGATCAGCCGCAGCTCAAGTGATAATTGAAATTTAG

Upstream 100 bases:

>100_bases
TTTGCAGGAATGAGCTACGAAGGTGTGGGTATTCCTGATTGCATCGCAGGAGCTCAAACAGCCGCTAAGGAATTAGTAGA
TTACTTGGAAGAGGTGTAAC

Downstream 100 bases:

>100_bases
AAAGGAAAGTGAACAATCATGGTGACAGGCTGGCATCGTCCTACATGGATTGAGATAGACCGCGCAGCAATTCGCGAAAA
TATAAAAAATGAACAAAATA

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS [H]

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MIKGIGLDMIDLERVKQVVEKNPRFIERVLTEKEIKQFEKYEGNRKIEFLAGRFAAKEAYAKANGTGFGKHLSFTDVEIL
QVEDGRPHVTLPVKSGENVFVSITHTARSAAAQVIIEI

Sequences:

>Translated_118_residues
MIKGIGLDMIDLERVKQVVEKNPRFIERVLTEKEIKQFEKYEGNRKIEFLAGRFAAKEAYAKANGTGFGKHLSFTDVEIL
QVEDGRPHVTLPVKSGENVFVSITHTARSAAAQVIIEI
>Mature_118_residues
MIKGIGLDMIDLERVKQVVEKNPRFIERVLTEKEIKQFEKYEGNRKIEFLAGRFAAKEAYAKANGTGFGKHLSFTDVEIL
QVEDGRPHVTLPVKSGENVFVSITHTARSAAAQVIIEI

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein [H]

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family [H]

Homologues:

Organism=Escherichia coli, GI1788916, Length=125, Percent_Identity=34.4, Blast_Score=64, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: =2.7.8.7 [H]

Molecular weight: Translated: 13257; Mature: 13257

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKGIGLDMIDLERVKQVVEKNPRFIERVLTEKEIKQFEKYEGNRKIEFLAGRFAAKEAY
CCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHH
AKANGTGFGKHLSFTDVEILQVEDGRPHVTLPVKSGENVFVSITHTARSAAAQVIIEI
HCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCEEEEEEECCHHHHHHEEEEEC
>Mature Secondary Structure
MIKGIGLDMIDLERVKQVVEKNPRFIERVLTEKEIKQFEKYEGNRKIEFLAGRFAAKEAY
CCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHH
AKANGTGFGKHLSFTDVEILQVEDGRPHVTLPVKSGENVFVSITHTARSAAAQVIIEI
HCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCEEEEEEECCHHHHHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA