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The map label for this gene is rbsR [H]

Identifier: 226223476

GI number: 226223476

Start: 896368

End: 897393

Strand: Reverse

Name: rbsR [H]

Synonym: Lm4b_00874

Alternate gene names: 226223476

Gene position: 897393-896368 (Counterclockwise)

Preceding gene: 226223487

Following gene: 226223467

Centisome position: 30.81

GC content: 38.5

Gene sequence:

>1026_bases
ATGAAGAAAGTTACGATGCAGGATATTGCTGACAGGCTAAATATAACCAAGAATTCAGTCTCGCAAGCTTTAGGCAATAA
AAATGGGGTTAGCGAACAAACTAAACTAGCCGTTTTTAAGATGGCAGATGAGCTAGGCTATAAATATAAAAGAGAAATCG
CGCGTGAGGTTGTGAAAGAAAAATTTGCGCTTTTAGCAACTTCTTTCGCCCTTTCGCAGCGCAGTTTTTTTGGCGAAATT
ATCGATAATATGAAACAAAGCATTATCGCTCACCAAGCCGAACTTATTATTTTTCCAGTTACGGATGAGGAAGCGTCTAC
TAATCAATTACCAGAGCAGCTCACAAGCGAGAACTGGACTGGGATTTTCTTACTTTCGCATATAAACACGGATTATAGTA
AAAAAGTTATCGATCTCGGCATGCCCGTTGTGCTTATAGATCATCATGATCCGCATCTAAAAGCCGACGCGGTTATCAGT
CAAAATAAAGATGGCGCTTTTATGGCTGTAGAATTTTTAATTCAAAATAAGCATCAGAAAATCGGTTTTCTCGGTGATGT
TACTTTCTCTCCAAGTTATGAAGAGCGGCTAGAAGGATACAAAAAAGCTTTGCACTACTATCACATTCCTTTTAACGAAA
AATACGCCATCACTCGTATCAAAGAAGAACAAACGACATTATATAGAACTTTAGATGAACTGGACGAACTCCCTACTGCT
TGGTTTTGTGTCAACTCAGGACTTGGGTTTATTCTCAATACTTACTTGCAATCAAAAGGCTATAATATCCCTAATGACTT
ATCGATTATTTGCTTTGATAATACCGAGTTTACTGTACTAAGCAATCCAAAGCTAACTACAATGTGTACCAACCTAAGCT
ATATGGGTGAGAAGGCTGTCGAACTCATGTATAATCGCATAAGAAAACCAGATGAAGGGTTTGTTCATCTGGCGCTTGCT
ACTAATTTAATAGCCCGAGATTCTGTTGGTGAAAACAAAAAAGCCGATTCAGCGAGTGAAAGCTGA

Upstream 100 bases:

>100_bases
AATAGAATTACTTTCTACATTACTTTTTAATTATAAAATTTTTGCTATTTTGTGAATTTACTTCTATAATAGAATAAATA
GAGGAAAACGGAGGGGAACC

Downstream 100 bases:

>100_bases
ATCGGTTTTCTTTATTGAGCATTTAAAACAGCGACATCTTTTTGCAAAAATGTTAAAACAGCTGCAAATAATTTGTCCGC
TTGTTCGTCCTGACAAATCA

Product: transcription regulator lacI family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKKVTMQDIADRLNITKNSVSQALGNKNGVSEQTKLAVFKMADELGYKYKREIAREVVKEKFALLATSFALSQRSFFGEI
IDNMKQSIIAHQAELIIFPVTDEEASTNQLPEQLTSENWTGIFLLSHINTDYSKKVIDLGMPVVLIDHHDPHLKADAVIS
QNKDGAFMAVEFLIQNKHQKIGFLGDVTFSPSYEERLEGYKKALHYYHIPFNEKYAITRIKEEQTTLYRTLDELDELPTA
WFCVNSGLGFILNTYLQSKGYNIPNDLSIICFDNTEFTVLSNPKLTTMCTNLSYMGEKAVELMYNRIRKPDEGFVHLALA
TNLIARDSVGENKKADSASES

Sequences:

>Translated_341_residues
MKKVTMQDIADRLNITKNSVSQALGNKNGVSEQTKLAVFKMADELGYKYKREIAREVVKEKFALLATSFALSQRSFFGEI
IDNMKQSIIAHQAELIIFPVTDEEASTNQLPEQLTSENWTGIFLLSHINTDYSKKVIDLGMPVVLIDHHDPHLKADAVIS
QNKDGAFMAVEFLIQNKHQKIGFLGDVTFSPSYEERLEGYKKALHYYHIPFNEKYAITRIKEEQTTLYRTLDELDELPTA
WFCVNSGLGFILNTYLQSKGYNIPNDLSIICFDNTEFTVLSNPKLTTMCTNLSYMGEKAVELMYNRIRKPDEGFVHLALA
TNLIARDSVGENKKADSASES
>Mature_341_residues
MKKVTMQDIADRLNITKNSVSQALGNKNGVSEQTKLAVFKMADELGYKYKREIAREVVKEKFALLATSFALSQRSFFGEI
IDNMKQSIIAHQAELIIFPVTDEEASTNQLPEQLTSENWTGIFLLSHINTDYSKKVIDLGMPVVLIDHHDPHLKADAVIS
QNKDGAFMAVEFLIQNKHQKIGFLGDVTFSPSYEERLEGYKKALHYYHIPFNEKYAITRIKEEQTTLYRTLDELDELPTA
WFCVNSGLGFILNTYLQSKGYNIPNDLSIICFDNTEFTVLSNPKLTTMCTNLSYMGEKAVELMYNRIRKPDEGFVHLALA
TNLIARDSVGENKKADSASES

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=328, Percent_Identity=27.1341463414634, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787948, Length=344, Percent_Identity=24.7093023255814, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994940, Length=323, Percent_Identity=26.3157894736842, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790194, Length=333, Percent_Identity=22.8228228228228, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789202, Length=288, Percent_Identity=24.3055555555556, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788474, Length=343, Percent_Identity=25.0728862973761, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789068, Length=299, Percent_Identity=24.7491638795987, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786540, Length=314, Percent_Identity=23.5668789808917, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38645; Mature: 38645

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVTMQDIADRLNITKNSVSQALGNKNGVSEQTKLAVFKMADELGYKYKREIAREVVKE
CCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
KFALLATSFALSQRSFFGEIIDNMKQSIIAHQAELIIFPVTDEEASTNQLPEQLTSENWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCC
GIFLLSHINTDYSKKVIDLGMPVVLIDHHDPHLKADAVISQNKDGAFMAVEFLIQNKHQK
EEEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCHHEECCCCCHHHHHHHHHHCCCCC
IGFLGDVTFSPSYEERLEGYKKALHYYHIPFNEKYAITRIKEEQTTLYRTLDELDELPTA
CEEEEEECCCCCHHHHHHHHHHHHHEEECCCCCCEEEEEECHHHHHHHHHHHHHHHCCCE
WFCVNSGLGFILNTYLQSKGYNIPNDLSIICFDNTEFTVLSNPKLTTMCTNLSYMGEKAV
EEEECCCHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCEEEEECCHHHHHHHHH
ELMYNRIRKPDEGFVHLALATNLIARDSVGENKKADSASES
HHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKVTMQDIADRLNITKNSVSQALGNKNGVSEQTKLAVFKMADELGYKYKREIAREVVKE
CCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
KFALLATSFALSQRSFFGEIIDNMKQSIIAHQAELIIFPVTDEEASTNQLPEQLTSENWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCC
GIFLLSHINTDYSKKVIDLGMPVVLIDHHDPHLKADAVISQNKDGAFMAVEFLIQNKHQK
EEEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCHHEECCCCCHHHHHHHHHHCCCCC
IGFLGDVTFSPSYEERLEGYKKALHYYHIPFNEKYAITRIKEEQTTLYRTLDELDELPTA
CEEEEEECCCCCHHHHHHHHHHHHHEEECCCCCCEEEEEECHHHHHHHHHHHHHHHCCCE
WFCVNSGLGFILNTYLQSKGYNIPNDLSIICFDNTEFTVLSNPKLTTMCTNLSYMGEKAV
EEEECCCHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCEEEEECCHHHHHHHHH
ELMYNRIRKPDEGFVHLALATNLIARDSVGENKKADSASES
HHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]