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The map label for this gene is potC [H]

Identifier: 226223426

GI number: 226223426

Start: 836447

End: 837253

Strand: Direct

Name: potC [H]

Synonym: Lm4b_00824

Alternate gene names: 226223426

Gene position: 836447-837253 (Clockwise)

Preceding gene: 226223425

Following gene: 226223427

Centisome position: 28.72

GC content: 38.79

Gene sequence:

>807_bases
ATGAAGAAAAGTAAATGGGGTACGATTTATTTAGTGCTTGTTTTTGTGATTTTATATGCGCCGATTTTCTATTTGATTTT
TTATTCGTTTAATAAAGGCGGCACGATGCATAATTTTAGTGGCTTTACGCTTGGCTATTATAAAGAAGTTTTCCAAGATA
CGCGCCTACTAATTATTGTTTTAAATACATTTGTAATTGCGCTGCTTTCTTCGGTGATTGCAACTATTATCGGCGTTTGC
GGGGCGCTGGCGATTAAATTTATGCCAAAACCATTCGCGAAAAATTCGCTTTTAAGTTTGAATAATGTGTTGATTGTTAG
CCCGGACGTTATTATCGGTGCTAGTTTCTTGATTTTCTTCACGATTTTAGGCGTAAAATTAGGGTTTATTTCCGTCCTAG
TGTCGCATATTGCCTTTAGTATTCCGATTGTCGTATTGATGATTTTGCCGAAATTGCAAGAAATGAGCCCGACGTTAATG
GATGCGGCGCGCGACTTAGGTGCAAGCCAGTGGCAAGTTCTTTCTAAGGTTATTTTGCCGTATATTATGCCAGGCGTTTT
AGCTGGATTTTTCATGGCATTAACGTACTCGCTAGATGATTTTGCGGTGACGTTCTTTGTAACTGGAAATGGCTTCTCGA
CATTGGCAGTGGAAATTTATTCCCGAGCTAGACAAGGGATTTCGCTTTCTATCAATGCTTTGTCGACACTGATTTTCTTA
TTCACGATTATTCTCGTGATCGGTTATTACTTTATCAACCAACGTAATACAAGTAAAAATATTCGGACGGGGGCGACGAA
AGAATGA

Upstream 100 bases:

>100_bases
AAGACTGGGGAATGGGTTCGACAATTGGCGTATTTTTAATTATTGCGATGATTTTAATTATGTTCCTAACAGGCTCGAAA
AAGAAAAGAGGTGCGCGTAA

Downstream 100 bases:

>100_bases
AGCAACTGCTGAAAATTTTTGTGCCAGTCATTGTTGTCGCACTCCTAATGATGCTACTTGCAACAACGATGAACCGCTCT
GAGGGCTATGCTGGGAGCAA

Product: spermidine/putrescine ABC transporter, permease protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKKSKWGTIYLVLVFVILYAPIFYLIFYSFNKGGTMHNFSGFTLGYYKEVFQDTRLLIIVLNTFVIALLSSVIATIIGVC
GALAIKFMPKPFAKNSLLSLNNVLIVSPDVIIGASFLIFFTILGVKLGFISVLVSHIAFSIPIVVLMILPKLQEMSPTLM
DAARDLGASQWQVLSKVILPYIMPGVLAGFFMALTYSLDDFAVTFFVTGNGFSTLAVEIYSRARQGISLSINALSTLIFL
FTIILVIGYYFINQRNTSKNIRTGATKE

Sequences:

>Translated_268_residues
MKKSKWGTIYLVLVFVILYAPIFYLIFYSFNKGGTMHNFSGFTLGYYKEVFQDTRLLIIVLNTFVIALLSSVIATIIGVC
GALAIKFMPKPFAKNSLLSLNNVLIVSPDVIIGASFLIFFTILGVKLGFISVLVSHIAFSIPIVVLMILPKLQEMSPTLM
DAARDLGASQWQVLSKVILPYIMPGVLAGFFMALTYSLDDFAVTFFVTGNGFSTLAVEIYSRARQGISLSINALSTLIFL
FTIILVIGYYFINQRNTSKNIRTGATKE
>Mature_268_residues
MKKSKWGTIYLVLVFVILYAPIFYLIFYSFNKGGTMHNFSGFTLGYYKEVFQDTRLLIIVLNTFVIALLSSVIATIIGVC
GALAIKFMPKPFAKNSLLSLNNVLIVSPDVIIGASFLIFFTILGVKLGFISVLVSHIAFSIPIVVLMILPKLQEMSPTLM
DAARDLGASQWQVLSKVILPYIMPGVLAGFFMALTYSLDDFAVTFFVTGNGFSTLAVEIYSRARQGISLSINALSTLIFL
FTIILVIGYYFINQRNTSKNIRTGATKE

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=242, Percent_Identity=36.7768595041322, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1787081, Length=268, Percent_Identity=30.5970149253731, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787714, Length=261, Percent_Identity=26.0536398467433, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788764, Length=179, Percent_Identity=29.608938547486, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29656; Mature: 29656

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSKWGTIYLVLVFVILYAPIFYLIFYSFNKGGTMHNFSGFTLGYYKEVFQDTRLLIIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHH
LNTFVIALLSSVIATIIGVCGALAIKFMPKPFAKNSLLSLNNVLIVSPDVIIGASFLIFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEECCHHHHHHHHHHHH
TILGVKLGFISVLVSHIAFSIPIVVLMILPKLQEMSPTLMDAARDLGASQWQVLSKVILP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHH
YIMPGVLAGFFMALTYSLDDFAVTFFVTGNGFSTLAVEIYSRARQGISLSINALSTLIFL
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHH
FTIILVIGYYFINQRNTSKNIRTGATKE
HHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKSKWGTIYLVLVFVILYAPIFYLIFYSFNKGGTMHNFSGFTLGYYKEVFQDTRLLIIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHH
LNTFVIALLSSVIATIIGVCGALAIKFMPKPFAKNSLLSLNNVLIVSPDVIIGASFLIFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEECCHHHHHHHHHHHH
TILGVKLGFISVLVSHIAFSIPIVVLMILPKLQEMSPTLMDAARDLGASQWQVLSKVILP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHH
YIMPGVLAGFFMALTYSLDDFAVTFFVTGNGFSTLAVEIYSRARQGISLSINALSTLIFL
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHH
FTIILVIGYYFINQRNTSKNIRTGATKE
HHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]