BacMap

Definition	Listeria monocytogenes Clip81459, complete genome.
Accession	NC_012488
Length	2,912,690

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The map label for this gene is yhxD [H]

Identifier: 226223299

GI number: 226223299

Start: 714895

End: 715779

Strand: Direct

Name: yhxD [H]

Synonym: Lm4b_00696

Alternate gene names: 226223299

Gene position: 714895-715779 (Clockwise)

Preceding gene: 226223298

Following gene: 226223300

Centisome position: 24.54

GC content: 41.58

Gene sequence:

>885_bases
ATGATGAATAAAGAAAATCCATTAAACAAATACCATACAGGAAAATTTGAAAAGCAACGCCAGGATTATCCTGGTTTGCA
AAGTAAAATGACGCCTGTTCCAGATACGGGCGAATCAAGTTATCAAGGCGCGAATAAATTAACCGGGAAAAAAGCCTTTG
TAACAGGAGGCGACTCGGGAATAGGTCGAGCTGCAGTAATTGCCTATGCTAGAGAAGGTGCTGATGTCGCGATAAATTAT
CATCCGGATGAAGAAGTAGATGCACAGGAAGTTAAAGCGATTGTTGAGGAAGCTGGACAGAAATGTGTCTTATTACCAGG
TGATTTGCGAAAAGAAGGTTTAGCGAAAGATTTAGTAAAAAAAGCATATAACGAGTTAGGTGGACTAGATATTCTAGTGC
TAAACGCTGGACTACAGCAATATCAATTAGATATTCAAAAACTTCCAGCTGAACAATTACGTGACACATTTGAAGTGAAC
GTCTTCTCCGTTGTGTTCGCAATTCAAGAAGCACTTAATTACTTAAAAGCAGGGGCAAGTATCATTTTAACGTCCTCCAT
TCAAGGCGTTAAACCAAGCGCTCACCTTGTTGACTATGCAATGACAAAAAGTAGTTTAATTTCGCTTACTAAAAGTTTAG
CGGCACAACTAGGGGAAAAAGGTATTCGAATTAATGCGGTTGCACCAGGACCAATTTGGACGGCGCTGCAAATTTCTGGG
GGACAACCACAAGATAGTATTCCTGCATTTGGTCAAGATCAGCCACTTGGACGAGCAGGGCAACCCGCAGAACTTGCGAG
CGCTTATGTGCTACTAGCATCAGATGAAGCAAGTTATACAACGGGCCAAGTATACGGAATTACCGGCGGAGCTCCTATTA
ATTAA

Upstream 100 bases:

>100_bases
ACTTGGCGCTAATATTTGGTGGATACTTATATTGGCCATTTTAATAATTTTCGTAGCCTACTTAGTCATGGGTTACGTTG
CAAAAATATAGGAGGTTTTT

Downstream 100 bases:

>100_bases
AAGCGAGGTGAAAGTTCGTGCCGTGGACAAAAAATGATTATCCGGATTCGTGGAAAAATCTAAGAAAGACCGAACGCGAA
AAAGCTATTGAAATCGGCAA

Product: oxidoreductase

Products: NA

Alternate protein names: ORFY [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MMNKENPLNKYHTGKFEKQRQDYPGLQSKMTPVPDTGESSYQGANKLTGKKAFVTGGDSGIGRAAVIAYAREGADVAINY
HPDEEVDAQEVKAIVEEAGQKCVLLPGDLRKEGLAKDLVKKAYNELGGLDILVLNAGLQQYQLDIQKLPAEQLRDTFEVN
VFSVVFAIQEALNYLKAGASIILTSSIQGVKPSAHLVDYAMTKSSLISLTKSLAAQLGEKGIRINAVAPGPIWTALQISG
GQPQDSIPAFGQDQPLGRAGQPAELASAYVLLASDEASYTTGQVYGITGGAPIN

Sequences:

>Translated_294_residues
MMNKENPLNKYHTGKFEKQRQDYPGLQSKMTPVPDTGESSYQGANKLTGKKAFVTGGDSGIGRAAVIAYAREGADVAINY
HPDEEVDAQEVKAIVEEAGQKCVLLPGDLRKEGLAKDLVKKAYNELGGLDILVLNAGLQQYQLDIQKLPAEQLRDTFEVN
VFSVVFAIQEALNYLKAGASIILTSSIQGVKPSAHLVDYAMTKSSLISLTKSLAAQLGEKGIRINAVAPGPIWTALQISG
GQPQDSIPAFGQDQPLGRAGQPAELASAYVLLASDEASYTTGQVYGITGGAPIN
>Mature_294_residues
MMNKENPLNKYHTGKFEKQRQDYPGLQSKMTPVPDTGESSYQGANKLTGKKAFVTGGDSGIGRAAVIAYAREGADVAINY
HPDEEVDAQEVKAIVEEAGQKCVLLPGDLRKEGLAKDLVKKAYNELGGLDILVLNAGLQQYQLDIQKLPAEQLRDTFEVN
VFSVVFAIQEALNYLKAGASIILTSSIQGVKPSAHLVDYAMTKSSLISLTKSLAAQLGEKGIRINAVAPGPIWTALQISG
GQPQDSIPAFGQDQPLGRAGQPAELASAYVLLASDEASYTTGQVYGITGGAPIN

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=30.2788844621514, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI59889578, Length=194, Percent_Identity=35.5670103092784, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=32.9317269076305, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=29.6, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=30.3846153846154, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=36.0824742268041, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=31.0344827586207, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=32.5, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=31.8897637795276, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=27.5720164609054, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=26.3779527559055, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=30.078125, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789378, Length=290, Percent_Identity=59.6551724137931, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=34.6938775510204, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=32.3770491803279, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=30.7392996108949, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=33.596837944664, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=32.6693227091633, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=31.6602316602317, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=32.3770491803279, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=28.6290322580645, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=26.4, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=28.6259541984733, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=27.8688524590164, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=31.9548872180451, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=33.0827067669173, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=30.4347826086957, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=32.0158102766798, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=28.2258064516129, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=30.3030303030303, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=31.5985130111524, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=29.2490118577075, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=30.0395256916996, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=33.4661354581673, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=30.6818181818182, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=31.3432835820896, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=30.7984790874525, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=27.1698113207547, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=26.1904761904762, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=256, Percent_Identity=30.078125, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=33.7209302325581, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=30.3370786516854, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=26.7399267399267, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=27.1698113207547, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=29.2592592592593, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=28.1368821292776, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=25.7575757575758, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=28.6852589641434, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=29.5880149812734, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=260, Percent_Identity=29.6153846153846, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=30.9701492537313, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=29.3172690763052, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=28.740157480315, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=30.8, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=30.4347826086957, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=30.4878048780488, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=29.5546558704453, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=32.4, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24644337, Length=213, Percent_Identity=33.8028169014084, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=32.2709163346614, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=31.640625, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31278; Mature: 31278

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNKENPLNKYHTGKFEKQRQDYPGLQSKMTPVPDTGESSYQGANKLTGKKAFVTGGDSG
CCCCCCCCCCCCCCCCHHHHCCCCCHHHCCCCCCCCCCCCCCCCHHCCCCEEEEECCCCC
IGRAAVIAYAREGADVAINYHPDEEVDAQEVKAIVEEAGQKCVLLPGDLRKEGLAKDLVK
CCHHHHEEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHH
KAYNELGGLDILVLNAGLQQYQLDIQKLPAEQLRDTFEVNVFSVVFAIQEALNYLKAGAS
HHHHHHCCEEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IILTSSIQGVKPSAHLVDYAMTKSSLISLTKSLAAQLGEKGIRINAVAPGPIWTALQISG
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECC
GQPQDSIPAFGQDQPLGRAGQPAELASAYVLLASDEASYTTGQVYGITGGAPIN
CCCCCCCCCCCCCCCCCCCCCCHHHHEEEEEEECCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MMNKENPLNKYHTGKFEKQRQDYPGLQSKMTPVPDTGESSYQGANKLTGKKAFVTGGDSG
CCCCCCCCCCCCCCCCHHHHCCCCCHHHCCCCCCCCCCCCCCCCHHCCCCEEEEECCCCC
IGRAAVIAYAREGADVAINYHPDEEVDAQEVKAIVEEAGQKCVLLPGDLRKEGLAKDLVK
CCHHHHEEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHH
KAYNELGGLDILVLNAGLQQYQLDIQKLPAEQLRDTFEVNVFSVVFAIQEALNYLKAGAS
HHHHHHCCEEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IILTSSIQGVKPSAHLVDYAMTKSSLISLTKSLAAQLGEKGIRINAVAPGPIWTALQISG
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECC
GQPQDSIPAFGQDQPLGRAGQPAELASAYVLLASDEASYTTGQVYGITGGAPIN
CCCCCCCCCCCCCCCCCCCCCCHHHHEEEEEEECCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 8196543 [H]