Click here to switch to the map view.

The map label for this gene is metX

Identifier: 226223223

GI number: 226223223

Start: 638957

End: 640063

Strand: Reverse

Name: metX

Synonym: Lm4b_00620

Alternate gene names: 226223223

Gene position: 640063-638957 (Counterclockwise)

Preceding gene: 226223224

Following gene: 226223211

Centisome position: 21.97

GC content: 43.54

Gene sequence:

>1107_bases
GTGACCTTACAACAAAAAGAACTATTTCAAAAAAGTCCTCTTCTGCTTGAAAATGGAGAAACATTAAGCCCTGTTTTAGT
CGGCTATGAAACATACGGGACACTTTCCGCCTCACGCGATAATTGCATTTTATTAGAACACGCCCTTACTGGGACGGCAC
ATGCGGCGAAACATTTTGAGAGTGACGCTCCTGGTTGGTGGGATGATTATATTGGTCCGGGGAAAACGATTGATACAGAC
AAATATTTTCTGGTTTGCACCAATGTATTTGGTGGTTGTAGTGGCACGACTGGACCTTCTTCGATTAATCCAAAAACTGG
CGAGCCTTTCCGCTTACAGTTTCCAGGTTTTTCGATTAAAGATATTATTAAAGTGCAGCGTGAACTTTTGGAGCAACTTG
GGGTTACGCGAATTGTTTCAGTGATTGGCGGATCGATGGGTGGTATGCAGGCGACGGAATGGGCGATTGATTATGCCGAT
ATCACGGATAGCATTATCAATATCGCCTCCCCGCTCGCTGCTGGACCTGATGCGATTGGTTACAACTTGATTATGCGCAT
GGCAATTTTGAACGACCCTGACTTTAATGGGGGCAACTATGTTGGTCAACCTGAGGGCGGACTTGCTACTGCGAGAATGG
TTGGGATGATGACTTACCGGACGAGCGAACTTTTCTCGAAACGCTTTGAACGTTTCACTGTCGCCGAGTCTTCTCCTGCC
GCTTTTTCAAAGGAGCATTTTCAAATTGAATCGTATTTGCAATATCAAGGGGATACTTTTGTCGAGCGATTTGACGCGAA
TAGCTACTTATATTTAACAAAGGCAATTGATTTGTTCGATGTTACTGCTCCCGCGAAAGATGATTTGCCTGCCTTTGCGA
AAATTAAAATTCCTTATTTGCTGATTGGCATCACGACAGATCAACTTTTCCGAATTCATGATTTGCGCCGCGGTTACGAG
CTTTTAAAAGAATGGGATGTGCCGGTTACTTATCATGAAGTGGCCTCCGAATACGGTCATGACGCTTTTCTAGTCAAAAA
AGAAGTCCCGAAATTCGAACCGCTCATTCGGTCATTTTTAAGTAATTTACCTGTTAAAAGCATATAA

Upstream 100 bases:

>100_bases
CCAGAGTCCATTCGCCTATCTATCGGAATCGAAAATGCCGATGATATTATCCAAGATTTAACGAAAGCATTAGAGCAAAT
TTAGGAGGAAGTGAAGAGAA

Downstream 100 bases:

>100_bases
AAAAGAGACCTCGGAAAATTTCCGGGGTCTCCTTTAATTAGTCTTTATAAATTGATTTCGTTCGGTTAAGCCAAGCATAG
CCGAGTCCGATAACAAGGCC

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MTLQQKELFQKSPLLLENGETLSPVLVGYETYGTLSASRDNCILLEHALTGTAHAAKHFESDAPGWWDDYIGPGKTIDTD
KYFLVCTNVFGGCSGTTGPSSINPKTGEPFRLQFPGFSIKDIIKVQRELLEQLGVTRIVSVIGGSMGGMQATEWAIDYAD
ITDSIINIASPLAAGPDAIGYNLIMRMAILNDPDFNGGNYVGQPEGGLATARMVGMMTYRTSELFSKRFERFTVAESSPA
AFSKEHFQIESYLQYQGDTFVERFDANSYLYLTKAIDLFDVTAPAKDDLPAFAKIKIPYLLIGITTDQLFRIHDLRRGYE
LLKEWDVPVTYHEVASEYGHDAFLVKKEVPKFEPLIRSFLSNLPVKSI

Sequences:

>Translated_368_residues
MTLQQKELFQKSPLLLENGETLSPVLVGYETYGTLSASRDNCILLEHALTGTAHAAKHFESDAPGWWDDYIGPGKTIDTD
KYFLVCTNVFGGCSGTTGPSSINPKTGEPFRLQFPGFSIKDIIKVQRELLEQLGVTRIVSVIGGSMGGMQATEWAIDYAD
ITDSIINIASPLAAGPDAIGYNLIMRMAILNDPDFNGGNYVGQPEGGLATARMVGMMTYRTSELFSKRFERFTVAESSPA
AFSKEHFQIESYLQYQGDTFVERFDANSYLYLTKAIDLFDVTAPAKDDLPAFAKIKIPYLLIGITTDQLFRIHDLRRGYE
LLKEWDVPVTYHEVASEYGHDAFLVKKEVPKFEPLIRSFLSNLPVKSI
>Mature_367_residues
TLQQKELFQKSPLLLENGETLSPVLVGYETYGTLSASRDNCILLEHALTGTAHAAKHFESDAPGWWDDYIGPGKTIDTDK
YFLVCTNVFGGCSGTTGPSSINPKTGEPFRLQFPGFSIKDIIKVQRELLEQLGVTRIVSVIGGSMGGMQATEWAIDYADI
TDSIINIASPLAAGPDAIGYNLIMRMAILNDPDFNGGNYVGQPEGGLATARMVGMMTYRTSELFSKRFERFTVAESSPAA
FSKEHFQIESYLQYQGDTFVERFDANSYLYLTKAIDLFDVTAPAKDDLPAFAKIKIPYLLIGITTDQLFRIHDLRRGYEL
LKEWDVPVTYHEVASEYGHDAFLVKKEVPKFEPLIRSFLSNLPVKSI

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=251, Percent_Identity=32.6693227091633, Blast_Score=146, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 40905; Mature: 40774

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQQKELFQKSPLLLENGETLSPVLVGYETYGTLSASRDNCILLEHALTGTAHAAKHFE
CCCCHHHHHHCCCCEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEEHHCCHHHHHHHHC
SDAPGWWDDYIGPGKTIDTDKYFLVCTNVFGGCSGTTGPSSINPKTGEPFRLQFPGFSIK
CCCCCCCHHCCCCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHH
DIIKVQRELLEQLGVTRIVSVIGGSMGGMQATEWAIDYADITDSIINIASPLAAGPDAIG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEHHHHHHHHHHHHHCCCCCCCHHH
YNLIMRMAILNDPDFNGGNYVGQPEGGLATARMVGMMTYRTSELFSKRFERFTVAESSPA
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
AFSKEHFQIESYLQYQGDTFVERFDANSYLYLTKAIDLFDVTAPAKDDLPAFAKIKIPYL
HHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEEEHHEECCCCCCCCCCCEEEEEEEEE
LIGITTDQLFRIHDLRRGYELLKEWDVPVTYHEVASEYGHDAFLVKKEVPKFEPLIRSFL
EEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
SNLPVKSI
HCCCCCCC
>Mature Secondary Structure 
TLQQKELFQKSPLLLENGETLSPVLVGYETYGTLSASRDNCILLEHALTGTAHAAKHFE
CCCHHHHHHCCCCEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEEHHCCHHHHHHHHC
SDAPGWWDDYIGPGKTIDTDKYFLVCTNVFGGCSGTTGPSSINPKTGEPFRLQFPGFSIK
CCCCCCCHHCCCCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHH
DIIKVQRELLEQLGVTRIVSVIGGSMGGMQATEWAIDYADITDSIINIASPLAAGPDAIG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEHHHHHHHHHHHHHCCCCCCCHHH
YNLIMRMAILNDPDFNGGNYVGQPEGGLATARMVGMMTYRTSELFSKRFERFTVAESSPA
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
AFSKEHFQIESYLQYQGDTFVERFDANSYLYLTKAIDLFDVTAPAKDDLPAFAKIKIPYL
HHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEEEHHEECCCCCCCCCCCEEEEEEEEE
LIGITTDQLFRIHDLRRGYELLKEWDVPVTYHEVASEYGHDAFLVKKEVPKFEPLIRSFL
EEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
SNLPVKSI
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]