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The map label for this gene is lacD [H]

Identifier: 226223168

GI number: 226223168

Start: 581267

End: 582283

Strand: Reverse

Name: lacD [H]

Synonym: Lm4b_00565

Alternate gene names: 226223168

Gene position: 582283-581267 (Counterclockwise)

Preceding gene: 226223170

Following gene: 226223164

Centisome position: 19.99

GC content: 38.25

Gene sequence:

>1017_bases
ATGGTACAAATAACAAAAGGTAAATTTGATGGTTTACAAAGACTCTCCAACGAAAAAGGTGTCATTGCAGCGCTTGCCAT
TGACCAACGTGGCTCACTCAAAAAAATGATCCAACAAGCAAAAGGAACAGAAAACAAAAAAGATGTGGAAGACTTCAAAC
AACTTGTTTCTGAAGAACTTACACCTTATGCTTCTGCGATTTTGCTTGATTTAGAATATGGTACTCCAGCAATCAAAGCT
CGCCACGAAGGTAGCGGACTTTTAACTTCTTATGAAAAAACAGGATATGACGCAACAACTCCCGGTAAACTTCCTGATTT
AATTGAAGATTTATCGGCACTTCGTATTAAAGAAAATGGCGGAGATGCTGTTAAAATTCTCGTTTATTATGATCCAGATG
AGCCAGCTGAAATTAATGAAATCAAATATGCCTTTTTAGAAAGAATCGGTGCTGAATGTCGCGCAGTTGATATTCCATTT
TTCTTAGAGCCAATTACTTATGATGCAACAGTTACTGATTCTGGTTCTTTAGAATATGCTAAATTGAAACCAGCAAAAGT
AAAAGCTTCAATTAAAGAATTCTCTAAACCTCGTTACGGTGTAGATGTACTTAAACTTGAAGTTCCAGTTAACTTTAAAT
ATGTGGAAGGTTTTGCGGAAGGTGAAGTCGCTTATACGCAAGACGAAGCAGCTCGTCATTTTGAAGAATGCTCTGACTTA
AGCCCACTTCCATTTATTTATCTTAGTGCTGGTGTAACTTCTGAAATGTTCCACAAAACAATCCAATTTGCGAACCAACA
TAACGTGCAGTATAGCGGCGTTCTTTGTGGTCGTGCAACTTGGGCTGATGGTATTGAAGTGTATGGCAAACAAGGCGATG
ACGCTTTACGCGAATGGCTTCGTACGCAAGGGAAAGAAAACATTACTTCTCTTGATAAATTGCTTGATGAAGGTGCCGTT
CCTTGGTGGACAAAATACGGTTCTTTTGAAGACGTACATGTAGTAGAAAAACAATAG

Upstream 100 bases:

>100_bases
GGAAATATACCTATGTTTTAAAAAAACTTTTCAGTGGTATAATAAGGAAGGATAAATTGATTAAGCAACGACAAATTGCT
ATAAAGGAGACTAGATAAAA

Downstream 100 bases:

>100_bases
CATGCGAAAAGCCTCCAGTTAATTGAATTTAGCTGGAGGCTTTTTTTATTAATTTTGATTTAAATAATTATACGCAAACT
GGGCATATAGCTCGGCGCCA

Product: tagatose 1,6-diphosphate aldolase

Products: NA

Alternate protein names: D-tagatose-1,6-bisphosphate aldolase; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MVQITKGKFDGLQRLSNEKGVIAALAIDQRGSLKKMIQQAKGTENKKDVEDFKQLVSEELTPYASAILLDLEYGTPAIKA
RHEGSGLLTSYEKTGYDATTPGKLPDLIEDLSALRIKENGGDAVKILVYYDPDEPAEINEIKYAFLERIGAECRAVDIPF
FLEPITYDATVTDSGSLEYAKLKPAKVKASIKEFSKPRYGVDVLKLEVPVNFKYVEGFAEGEVAYTQDEAARHFEECSDL
SPLPFIYLSAGVTSEMFHKTIQFANQHNVQYSGVLCGRATWADGIEVYGKQGDDALREWLRTQGKENITSLDKLLDEGAV
PWWTKYGSFEDVHVVEKQ

Sequences:

>Translated_338_residues
MVQITKGKFDGLQRLSNEKGVIAALAIDQRGSLKKMIQQAKGTENKKDVEDFKQLVSEELTPYASAILLDLEYGTPAIKA
RHEGSGLLTSYEKTGYDATTPGKLPDLIEDLSALRIKENGGDAVKILVYYDPDEPAEINEIKYAFLERIGAECRAVDIPF
FLEPITYDATVTDSGSLEYAKLKPAKVKASIKEFSKPRYGVDVLKLEVPVNFKYVEGFAEGEVAYTQDEAARHFEECSDL
SPLPFIYLSAGVTSEMFHKTIQFANQHNVQYSGVLCGRATWADGIEVYGKQGDDALREWLRTQGKENITSLDKLLDEGAV
PWWTKYGSFEDVHVVEKQ
>Mature_338_residues
MVQITKGKFDGLQRLSNEKGVIAALAIDQRGSLKKMIQQAKGTENKKDVEDFKQLVSEELTPYASAILLDLEYGTPAIKA
RHEGSGLLTSYEKTGYDATTPGKLPDLIEDLSALRIKENGGDAVKILVYYDPDEPAEINEIKYAFLERIGAECRAVDIPF
FLEPITYDATVTDSGSLEYAKLKPAKVKASIKEFSKPRYGVDVLKLEVPVNFKYVEGFAEGEVAYTQDEAARHFEECSDL
SPLPFIYLSAGVTSEMFHKTIQFANQHNVQYSGVLCGRATWADGIEVYGKQGDDALREWLRTQGKENITSLDKLLDEGAV
PWWTKYGSFEDVHVVEKQ

Specific function: Unknown

COG id: COG3684

COG function: function code G; Tagatose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase lacD family [H]

Homologues:

Organism=Escherichia coli, GI1790314, Length=273, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002915 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 37698; Mature: 37698

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQITKGKFDGLQRLSNEKGVIAALAIDQRGSLKKMIQQAKGTENKKDVEDFKQLVSEEL
CEEECCCCHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
TPYASAILLDLEYGTPAIKARHEGSGLLTSYEKTGYDATTPGKLPDLIEDLSALRIKENG
CCCEEEEEEEECCCCCCEEEECCCCCCEEEHHHCCCCCCCCCCCHHHHHHHHHEEEECCC
GDAVKILVYYDPDEPAEINEIKYAFLERIGAECRAVDIPFFLEPITYDATVTDSGSLEYA
CCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCEEECCEEECEEECCCCCEEEE
KLKPAKVKASIKEFSKPRYGVDVLKLEVPVNFKYVEGFAEGEVAYTQDEAARHFEECSDL
ECCCHHHHHHHHHHCCCCCCCEEEEEEECCCEEEECCCCCCCEEECHHHHHHHHHHHCCC
SPLPFIYLSAGVTSEMFHKTIQFANQHNVQYSGVLCGRATWADGIEVYGKQGDDALREWL
CCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHEECCCCHHHHHHHH
RTQGKENITSLDKLLDEGAVPWWTKYGSFEDVHVVEKQ
HHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MVQITKGKFDGLQRLSNEKGVIAALAIDQRGSLKKMIQQAKGTENKKDVEDFKQLVSEEL
CEEECCCCHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
TPYASAILLDLEYGTPAIKARHEGSGLLTSYEKTGYDATTPGKLPDLIEDLSALRIKENG
CCCEEEEEEEECCCCCCEEEECCCCCCEEEHHHCCCCCCCCCCCHHHHHHHHHEEEECCC
GDAVKILVYYDPDEPAEINEIKYAFLERIGAECRAVDIPFFLEPITYDATVTDSGSLEYA
CCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCEEECCEEECEEECCCCCEEEE
KLKPAKVKASIKEFSKPRYGVDVLKLEVPVNFKYVEGFAEGEVAYTQDEAARHFEECSDL
ECCCHHHHHHHHHHCCCCCCCEEEEEEECCCEEEECCCCCCCEEECHHHHHHHHHHHCCC
SPLPFIYLSAGVTSEMFHKTIQFANQHNVQYSGVLCGRATWADGIEVYGKQGDDALREWL
CCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHEECCCCHHHHHHHH
RTQGKENITSLDKLLDEGAVPWWTKYGSFEDVHVVEKQ
HHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]