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The map label for this gene is mta [H]

Identifier: 226223155

GI number: 226223155

Start: 565458

End: 566198

Strand: Reverse

Name: mta [H]

Synonym: Lm4b_00552

Alternate gene names: 226223155

Gene position: 566198-565458 (Counterclockwise)

Preceding gene: 226223164

Following gene: 226223154

Centisome position: 19.44

GC content: 36.71

Gene sequence:

>741_bases
ATGCAAATAAAAGAATTAGCTGAACTCACTGGTGTAAGTGTGCGCACACTCCACCACTACGATAAAATAGGCCTACTTGT
CCCGCAAAAAGATGACCGGAATGGCTATCGTATTTATTCAGAAAACGATGTCGACAAATTACAACAAATTCTTTTCTTTA
AAGAACTCGATTTCCCTTTGAAAAAAATAAAACAAATTCTTGATGATCCTTTTTTCGATAAAAATGTTGCTTTAGATTTG
CAGCGTCACTTACTAATAGAAAAAAAGCAGCGCATTGAAACCATGCTAGCAACCCTCGACCAGACCATCAGGAATGAAAA
AGGAGAAATAACAATGACAAACAAAGAAAAATTCACTGGTTTTGATTTTTCCACCAATCCATACGAAGAAGAAGCAAAAA
AACGTTGGGGCGATAAAGTAGTAGAAAAAGCCAATGAAAAAGTAAATAATATGAACGAAAAAGAAAAATTAACTTTAAAA
GAAAGTTTCGACGCAGAATTTCGTCATTTAGCATCTGTTCGAGAACTCTCTCCCGAGTCAGAAGAAGCCCAACTCGCAAT
TGACCATTTTTTCCATTACTTGAATGACACCCACGGCAATATTTATTCCCTAGAAGCCTTTGCTGATCTTGGGGAAATGT
ACGTTGCTGATGAGCGCTTCACTAAAAATATCGATCAGTTCGGTGATGGCCTTTCTCACTTCCTCAAAGAAGCCATGAAC
ATTTATGCCAAAAACAAATAA

Upstream 100 bases:

>100_bases
AATTTTCTTTTCCACTAAAAAGGTTATAATAAACACAAATTCAAGCTTGACTATCACGCGACGTCATACTTTATAGTAAA
AGCAGAAGGAGGAATCACTC

Downstream 100 bases:

>100_bases
AAAAAGCCACGATTTCTTAAAAAGAGATCGTGGTTTTATGATTGGTATAACAAAGAACGGGGTAAATAGTATAAGATTTC
ATTAATATGTATTTATGATG

Product: transcription regulator (MerR family)

Products: NA

Alternate protein names: Multidrug transporter activation protein [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MQIKELAELTGVSVRTLHHYDKIGLLVPQKDDRNGYRIYSENDVDKLQQILFFKELDFPLKKIKQILDDPFFDKNVALDL
QRHLLIEKKQRIETMLATLDQTIRNEKGEITMTNKEKFTGFDFSTNPYEEEAKKRWGDKVVEKANEKVNNMNEKEKLTLK
ESFDAEFRHLASVRELSPESEEAQLAIDHFFHYLNDTHGNIYSLEAFADLGEMYVADERFTKNIDQFGDGLSHFLKEAMN
IYAKNK

Sequences:

>Translated_246_residues
MQIKELAELTGVSVRTLHHYDKIGLLVPQKDDRNGYRIYSENDVDKLQQILFFKELDFPLKKIKQILDDPFFDKNVALDL
QRHLLIEKKQRIETMLATLDQTIRNEKGEITMTNKEKFTGFDFSTNPYEEEAKKRWGDKVVEKANEKVNNMNEKEKLTLK
ESFDAEFRHLASVRELSPESEEAQLAIDHFFHYLNDTHGNIYSLEAFADLGEMYVADERFTKNIDQFGDGLSHFLKEAMN
IYAKNK
>Mature_246_residues
MQIKELAELTGVSVRTLHHYDKIGLLVPQKDDRNGYRIYSENDVDKLQQILFFKELDFPLKKIKQILDDPFFDKNVALDL
QRHLLIEKKQRIETMLATLDQTIRNEKGEITMTNKEKFTGFDFSTNPYEEEAKKRWGDKVVEKANEKVNNMNEKEKLTLK
ESFDAEFRHLASVRELSPESEEAQLAIDHFFHYLNDTHGNIYSLEAFADLGEMYVADERFTKNIDQFGDGLSHFLKEAMN
IYAKNK

Specific function: Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 28861; Mature: 28861

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKELAELTGVSVRTLHHYDKIGLLVPQKDDRNGYRIYSENDVDKLQQILFFKELDFPL
CCHHHHHHHHCCHHHHHHHHHHHCEEECCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCH
KKIKQILDDPFFDKNVALDLQRHLLIEKKQRIETMLATLDQTIRNEKGEITMTNKEKFTG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
FDFSTNPYEEEAKKRWGDKVVEKANEKVNNMNEKEKLTLKESFDAEFRHLASVRELSPES
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EEAQLAIDHFFHYLNDTHGNIYSLEAFADLGEMYVADERFTKNIDQFGDGLSHFLKEAMN
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYAKNK
HHCCCC
>Mature Secondary Structure
MQIKELAELTGVSVRTLHHYDKIGLLVPQKDDRNGYRIYSENDVDKLQQILFFKELDFPL
CCHHHHHHHHCCHHHHHHHHHHHCEEECCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCH
KKIKQILDDPFFDKNVALDLQRHLLIEKKQRIETMLATLDQTIRNEKGEITMTNKEKFTG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
FDFSTNPYEEEAKKRWGDKVVEKANEKVNNMNEKEKLTLKESFDAEFRHLASVRELSPES
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EEAQLAIDHFFHYLNDTHGNIYSLEAFADLGEMYVADERFTKNIDQFGDGLSHFLKEAMN
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYAKNK
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9150240; 9384377 [H]