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The map label for this gene is inlD

Identifier: 226222898

GI number: 226222898

Start: 290922

End: 292628

Strand: Direct

Name: inlD

Synonym: Lm4b_00290

Alternate gene names: 226222898

Gene position: 290922-292628 (Clockwise)

Preceding gene: 226222897

Following gene: 226222899

Centisome position: 9.99

GC content: 36.79

Gene sequence:

>1707_bases
ATGAAAAGAAAAAAAACAGCATTACGTATCTTGGTAACTCTGGCTGTAGTAATGGCAATTAGCTTTTGGGTAGGGACTAG
CTCAAAAGAGGAAGTACAGGCGGCAGTAATTGATCAACCGACGCCAATTAATGAAATTTTTACAGATGAGAATTTAGCAA
ACGCAATAAAAGCAACTTTAAATAAACCTAGTACTACATCTGACGTTTCACAAGCAGAGCTAGATTCTATAAGTGAAGTA
ACGGCAGAAAGTAGCAATATAGCTTCTTTAGAGGGGGCGCAGTATTTAAATAATATAGATACATTAATTTTAAATAATAA
TAAAATAACGGATTTAAATTCACTTGCAGGACTATCTAAATTAAGGATATTAGAAGCAAATGACAATCAATTAAGCGATA
TAAGTGCACTAGCAAATGTGACAAGTCTGCACCAATTAAGATTAGCTGGAAATCAAATAAAACAGTTAAATGGAGTTAGT
AATTTAATCAATCTAGAAACCATAGAACTAAGCAACAATCAAATAACGGATATAAGCCCAGTTTCAGGTTTGAAAAACTT
AATTGGTCTTGGAATAGATTATAATGATATCAGTGATTTAAGCCCAATTGCTGGCTTAGCAAAGTTAAGTCATTTAACTG
CAGACAATAACCAAATAAGTGATTTGAGTCCTATTTCAAGCTTAGGGGCTATGGAAATTATGCGACTAGATAAAAATCAA
ATCAGTGATGTAACCCCAATTGCGAATTTGGCTAATTTAAGCTATGTATTTTTAGCTGAAAATCAAATCAGTGATATTAG
TTCTTTACAACCACTTTTTAATTCACCTAATTTTTTTGGTATTACTTTAGACAATCAAAAAATAACGAGTGAACCAGTAT
TGTACCAACAAGAGCTTGTGGTCCCTAATAACATTAAGGATGAAATGGGAGCGTTAATCTCACCAGATACAATTAGCGAT
AATGGTGTTTATGCAAGCCCGAATATTAAGTGGAACTTGGCTAATTATACTAACCAAGTAAGTTACACATTTAATAAACA
ATTAGCACAGGGTTCTTTTAGCGGAACAGTGACCCAACCACTTCACAATGCTTATACAGCGACATTTGACGTAGATGGAG
TGAAAACAAATGAAGTAGTGGAAGAAACGAAATTGCTTCAAGAACCAACAGCTCCAACGAAAGAAGGATACACTTTCACA
GGCTGGTATGATGCGAAAACTGGCGGGAATAAATGGGATTTTGCGACAGACAAAATGCCAGCAGAAGACATCACATTATA
CGCGCAGTTCACGATTAATAGCTATACAGCCACATTCGACATCGATGGGAAATTAACGACGCAAAAAGTCACTTATCAAA
GCTTGCTAGAAGAACCAGCAGCGCCAACGAAGGATGGCTATACGTTCAAAGGTTGGTATGATGCTAAAACAGGTGGAACT
AAATGGGATTTTGCGACAGGAAAAATGCCGGCGGGAAATATAACGCTATACGCCCAGTTTACTAAAAATGCCACCCCAGA
TTCCAATGACCCAACAACGGTTACCCCAACAGGAAATGGCAATGGGACAAGTACCCCAAGCAATTCAGGTGGAAATACCA
CGCTTCCGACAGCTGGGGACGAAAATACCATGCTTCCAATTTTTGTAGGAGTTTTCTTGTTAGGAACAGCAACGCTTATT
CTCCGCAAAACAATCAAAGTAAAATAA

Upstream 100 bases:

>100_bases
GTGATTAAACGAAATTTGATTAAGTTATAATGAAATAATTCAGCTATGAATACATACACAGTCCTAAGAAATAGAATAAT
ATTATAAAGGAGATAAGTTA

Downstream 100 bases:

>100_bases
CAACAAAAAAACAGCTGAGGTCTATAGTTTTTCTATAGATTTCGGCTGTTTTTTTATTAGCAAAGAAATTCATCTAAACG
TCACAACTAAAACGGTAACA

Product: internalin D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MKRKKTALRILVTLAVVMAISFWVGTSSKEEVQAAVIDQPTPINEIFTDENLANAIKATLNKPSTTSDVSQAELDSISEV
TAESSNIASLEGAQYLNNIDTLILNNNKITDLNSLAGLSKLRILEANDNQLSDISALANVTSLHQLRLAGNQIKQLNGVS
NLINLETIELSNNQITDISPVSGLKNLIGLGIDYNDISDLSPIAGLAKLSHLTADNNQISDLSPISSLGAMEIMRLDKNQ
ISDVTPIANLANLSYVFLAENQISDISSLQPLFNSPNFFGITLDNQKITSEPVLYQQELVVPNNIKDEMGALISPDTISD
NGVYASPNIKWNLANYTNQVSYTFNKQLAQGSFSGTVTQPLHNAYTATFDVDGVKTNEVVEETKLLQEPTAPTKEGYTFT
GWYDAKTGGNKWDFATDKMPAEDITLYAQFTINSYTATFDIDGKLTTQKVTYQSLLEEPAAPTKDGYTFKGWYDAKTGGT
KWDFATGKMPAGNITLYAQFTKNATPDSNDPTTVTPTGNGNGTSTPSNSGGNTTLPTAGDENTMLPIFVGVFLLGTATLI
LRKTIKVK

Sequences:

>Translated_568_residues
MKRKKTALRILVTLAVVMAISFWVGTSSKEEVQAAVIDQPTPINEIFTDENLANAIKATLNKPSTTSDVSQAELDSISEV
TAESSNIASLEGAQYLNNIDTLILNNNKITDLNSLAGLSKLRILEANDNQLSDISALANVTSLHQLRLAGNQIKQLNGVS
NLINLETIELSNNQITDISPVSGLKNLIGLGIDYNDISDLSPIAGLAKLSHLTADNNQISDLSPISSLGAMEIMRLDKNQ
ISDVTPIANLANLSYVFLAENQISDISSLQPLFNSPNFFGITLDNQKITSEPVLYQQELVVPNNIKDEMGALISPDTISD
NGVYASPNIKWNLANYTNQVSYTFNKQLAQGSFSGTVTQPLHNAYTATFDVDGVKTNEVVEETKLLQEPTAPTKEGYTFT
GWYDAKTGGNKWDFATDKMPAEDITLYAQFTINSYTATFDIDGKLTTQKVTYQSLLEEPAAPTKDGYTFKGWYDAKTGGT
KWDFATGKMPAGNITLYAQFTKNATPDSNDPTTVTPTGNGNGTSTPSNSGGNTTLPTAGDENTMLPIFVGVFLLGTATLI
LRKTIKVK
>Mature_568_residues
MKRKKTALRILVTLAVVMAISFWVGTSSKEEVQAAVIDQPTPINEIFTDENLANAIKATLNKPSTTSDVSQAELDSISEV
TAESSNIASLEGAQYLNNIDTLILNNNKITDLNSLAGLSKLRILEANDNQLSDISALANVTSLHQLRLAGNQIKQLNGVS
NLINLETIELSNNQITDISPVSGLKNLIGLGIDYNDISDLSPIAGLAKLSHLTADNNQISDLSPISSLGAMEIMRLDKNQ
ISDVTPIANLANLSYVFLAENQISDISSLQPLFNSPNFFGITLDNQKITSEPVLYQQELVVPNNIKDEMGALISPDTISD
NGVYASPNIKWNLANYTNQVSYTFNKQLAQGSFSGTVTQPLHNAYTATFDVDGVKTNEVVEETKLLQEPTAPTKEGYTFT
GWYDAKTGGNKWDFATDKMPAEDITLYAQFTINSYTATFDIDGKLTTQKVTYQSLLEEPAAPTKDGYTFKGWYDAKTGGT
KWDFATGKMPAGNITLYAQFTKNATPDSNDPTTVTPTGNGNGTSTPSNSGGNTTLPTAGDENTMLPIFVGVFLLGTATLI
LRKTIKVK

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=204, Percent_Identity=29.9019607843137, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI55743114, Length=192, Percent_Identity=31.7708333333333, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI21389483, Length=194, Percent_Identity=30.4123711340206, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536161, Length=177, Percent_Identity=30.5084745762712, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531555, Length=217, Percent_Identity=27.6497695852535, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17554124, Length=196, Percent_Identity=26.0204081632653, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71984630, Length=161, Percent_Identity=31.6770186335404, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21358617, Length=191, Percent_Identity=28.7958115183246, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 61400; Mature: 61400

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKKTALRILVTLAVVMAISFWVGTSSKEEVQAAVIDQPTPINEIFTDENLANAIKATL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHC
NKPSTTSDVSQAELDSISEVTAESSNIASLEGAQYLNNIDTLILNNNKITDLNSLAGLSK
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEECCCCCCCHHHHCCCCE
LRILEANDNQLSDISALANVTSLHQLRLAGNQIKQLNGVSNLINLETIELSNNQITDISP
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEEECCCCCCCCCH
VSGLKNLIGLGIDYNDISDLSPIAGLAKLSHLTADNNQISDLSPISSLGAMEIMRLDKNQ
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCHHH
ISDVTPIANLANLSYVFLAENQISDISSLQPLFNSPNFFGITLDNQKITSEPVLYQQELV
CCCCCCHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEC
VPNNIKDEMGALISPDTISDNGVYASPNIKWNLANYTNQVSYTFNKQLAQGSFSGTVTQP
CCCCCHHHHCCEECCCCCCCCCEEECCCEEEEECCCCCEEEEEEHHHHHCCCCCCCCCCC
LHNAYTATFDVDGVKTNEVVEETKLLQEPTAPTKEGYTFTGWYDAKTGGNKWDFATDKMP
CCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCC
AEDITLYAQFTINSYTATFDIDGKLTTQKVTYQSLLEEPAAPTKDGYTFKGWYDAKTGGT
CCCEEEEEEEEEEEEEEEEEECCCEEEHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCC
KWDFATGKMPAGNITLYAQFTKNATPDSNDPTTVTPTGNGNGTSTPSNSGGNTTLPTAGD
EEEECCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEECCCCCC
ENTMLPIFVGVFLLGTATLILRKTIKVK
CCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRKKTALRILVTLAVVMAISFWVGTSSKEEVQAAVIDQPTPINEIFTDENLANAIKATL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHC
NKPSTTSDVSQAELDSISEVTAESSNIASLEGAQYLNNIDTLILNNNKITDLNSLAGLSK
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEECCCCCCCHHHHCCCCE
LRILEANDNQLSDISALANVTSLHQLRLAGNQIKQLNGVSNLINLETIELSNNQITDISP
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEEECCCCCCCCCH
VSGLKNLIGLGIDYNDISDLSPIAGLAKLSHLTADNNQISDLSPISSLGAMEIMRLDKNQ
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCHHH
ISDVTPIANLANLSYVFLAENQISDISSLQPLFNSPNFFGITLDNQKITSEPVLYQQELV
CCCCCCHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEC
VPNNIKDEMGALISPDTISDNGVYASPNIKWNLANYTNQVSYTFNKQLAQGSFSGTVTQP
CCCCCHHHHCCEECCCCCCCCCEEECCCEEEEECCCCCEEEEEEHHHHHCCCCCCCCCCC
LHNAYTATFDVDGVKTNEVVEETKLLQEPTAPTKEGYTFTGWYDAKTGGNKWDFATDKMP
CCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCC
AEDITLYAQFTINSYTATFDIDGKLTTQKVTYQSLLEEPAAPTKDGYTFKGWYDAKTGGT
CCCEEEEEEEEEEEEEEEEEECCCEEEHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCC
KWDFATGKMPAGNITLYAQFTKNATPDSNDPTTVTPTGNGNGTSTPSNSGGNTTLPTAGD
EEEECCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEECCCCCC
ENTMLPIFVGVFLLGTATLILRKTIKVK
CCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]