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The map label for this gene is efp

Identifier: 225858286

GI number: 225858286

Start: 451188

End: 451748

Strand: Reverse

Name: efp

Synonym: SP70585_0504

Alternate gene names: 225858286

Gene position: 451748-451188 (Counterclockwise)

Preceding gene: 225858287

Following gene: 225858285

Centisome position: 20.68

GC content: 41.71

Gene sequence:

>561_bases
ATGATTGAAGCAAGTAAATTAAAAGCTGGTATGACCTTTGAAACAGCTGACGGCAAATTGATTCGCGTTTTGGAAGCTAG
TCACCACAAGCCAGGTAAAGGAAACACGATCATGCGTATGAAATTGCGTGATGTCCGTACTGGTTCTACATTTGACACAA
GCTACCGTCCAGAGGAAAAATTTGAACAAGCTATTATCGAGACTGTCCCAGCTCAATACTTGTACAAAATGGATGACACA
GCATACTTCATGAATACAGAAACTTACGACCAGTACGAAATCCCTGTAGTCAATGTTGAAAACGAATTGCTTTACATCCT
TGAAAACTCTGATGTGAAAATCCAATTCTACGGAACTGAAGTGATCGGTGTCACCGTTCCTACTACTGTTGAGTTGACAG
TTGCTGAAACTCAACCATCTATCAAAGGTGCTACTGTTACAGGTTCTGGCAAACCAGCAACGATGGAAACTGGACTTGTC
GTAAACGTTCCAGACTTCATCGAAGCAGGACAAAAACTCGTTATCAACACTGCAGAAGGAACTTACGTTTCTCGTGCCTA
A

Upstream 100 bases:

>100_bases
TTTTTCTTCTCTACCAACTCCCAATAACTATTTTGGCTTTATTTCCAGAGTATTTTATGGTAAAATGAAGAGTAATAATA
TTTATTAAAGAGGTAAAAAC

Downstream 100 bases:

>100_bases
TCTCTAGAAAGAGGTCATTCTATGGGAATTGAAGAACAACTTGGCGAAATCGTTATCGCCCCACGTGTACTTGAAAAAAT
CATTGCTATCGCTACTGCAA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDT
AYFMNTETYDQYEIPVVNVENELLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
VNVPDFIEAGQKLVINTAEGTYVSRA

Sequences:

>Translated_186_residues
MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDT
AYFMNTETYDQYEIPVVNVENELLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
VNVPDFIEAGQKLVINTAEGTYVSRA
>Mature_186_residues
MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDT
AYFMNTETYDQYEIPVVNVENELLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
VNVPDFIEAGQKLVINTAEGTYVSRA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=32.4175824175824, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI87082061, Length=190, Percent_Identity=30.5263157894737, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20601; Mature: 20601

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTSYRPEEK
CCCHHHCCCCCEEECCCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCHHH
FEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENELLYILENSDVKIQFYGTE
HHHHHHHHCCHHHEEEECCCEEEEECCCCCEEECEEEEECCEEEEEEECCCEEEEEECEE
VIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLVVNVPDFIEAGQKLVINTAEG
EEEEECCCEEEEEEECCCCCCCCEEEECCCCCCEEECCEEEECHHHHHCCCEEEEECCCC
TYVSRA
EEEECC
>Mature Secondary Structure
MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTSYRPEEK
CCCHHHCCCCCEEECCCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCHHH
FEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENELLYILENSDVKIQFYGTE
HHHHHHHHCCHHHEEEECCCEEEEECCCCCEEECEEEEECCEEEEEEECCCEEEEEECEE
VIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLVVNVPDFIEAGQKLVINTAEG
EEEEECCCEEEEEEECCCCCCCCEEEECCCCCCEEECCEEEECHHHHHCCCEEEEECCCC
TYVSRA
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA