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The map label for this gene is dapA [H]

Identifier: 225686216

GI number: 225686216

Start: 369938

End: 370855

Strand: Reverse

Name: dapA [H]

Synonym: BMEA_B0384

Alternate gene names: 225686216

Gene position: 370855-369938 (Counterclockwise)

Preceding gene: 225686217

Following gene: 225686215

Centisome position: 31.28

GC content: 59.8

Gene sequence:

>918_bases
ATGTCGAAATTTTTTGGCGTTGTCCCTCCCGTCGTCACTCCGCTTAACGATGACCATTCGGTCGATTACGATTCCTATAC
CCGCGTTCTCGAACATCTGATCGAAGGCGGCTGCCATGGCCTTTTTGCCCTCGGTTCCACCAGCGAGGTGGTGTTCTATG
ACGAGGCAGACCGGCGCAGGATTCTTGAACATACGGTGAAAGTGGCGAATGGCCGTGTTCCGGTCATTGCCGGTGTCATA
GACCCGGCGACCGACCGCGTGATTGCCCATGCAAAAGCCGCAAAGGACGTTGGCGCCGATGCGGTCGTCGTCACGGCTCC
TTTCTATACAATCACCAGCCAGCCCGAGATCATCGATCATTTCCGCATGGTGCGCGATGCGGTCGATATTCCGCTGATTG
CCTACGACATCCCGGTCTGCGTCCATGCCAAGCTTACACGCCAGACCGTGGTAACGCTTGCCAATGAAGGCACGATCATC
GGCCTGAAGGATTCCTCCGGCGATGACGGCAATTTCCGCTATGCACTGCTCGATCTGGCTAAAAACAAAAACATGTTCCT
GATGACCGGCTCGGAAATCGTGGTGGACAATGCGCTTTTGATGGGCGCGCACGGCGTTGTTCCCGGCCTCGCCAATGTCG
ATCCGGCAGGCTATGTGCGGCTTTGGGATGCCGCGCAGCGCGGCGACTGGGTGGCCGCGCGCAAGGAACAGGAGCGCCTT
TGCCGCCTCTTCGAGATCGTCTGGGTTGGTGCGGGGCGCGTCAGCGGCGGAGCCGCAGGCGTCGGCGCTTTCAAGACCGC
GATGCGCAGTCTCGGCATTATTTCCACCAACAAGATGGCGCGCCCGCGCCAGGCGCAGAATACGGCGGAAGCAGGCCGCA
TAGACGCGATCCTGCGCAGCGTCGGCCTCCTGGATTGA

Upstream 100 bases:

>100_bases
CTCGTGCTGGCCGTATTGGCGATCAACTTTATCGGTGATGGTCTGAGGGATGCCTTTGACCCCCGCGCAGAACTCAACTG
AACCAGAAAGCGAATTTGAA

Downstream 100 bases:

>100_bases
GGCAAGCATCATGAGCCGGCAACCGATCCTCGATATCAAGGGACTGCGCACCGTCTTCCGCACCCGCGCGCGCGAGATCG
TCGCGGTCAATGATGTGGAC

Product: Dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSKFFGVVPPVVTPLNDDHSVDYDSYTRVLEHLIEGGCHGLFALGSTSEVVFYDEADRRRILEHTVKVANGRVPVIAGVI
DPATDRVIAHAKAAKDVGADAVVVTAPFYTITSQPEIIDHFRMVRDAVDIPLIAYDIPVCVHAKLTRQTVVTLANEGTII
GLKDSSGDDGNFRYALLDLAKNKNMFLMTGSEIVVDNALLMGAHGVVPGLANVDPAGYVRLWDAAQRGDWVAARKEQERL
CRLFEIVWVGAGRVSGGAAGVGAFKTAMRSLGIISTNKMARPRQAQNTAEAGRIDAILRSVGLLD

Sequences:

>Translated_305_residues
MSKFFGVVPPVVTPLNDDHSVDYDSYTRVLEHLIEGGCHGLFALGSTSEVVFYDEADRRRILEHTVKVANGRVPVIAGVI
DPATDRVIAHAKAAKDVGADAVVVTAPFYTITSQPEIIDHFRMVRDAVDIPLIAYDIPVCVHAKLTRQTVVTLANEGTII
GLKDSSGDDGNFRYALLDLAKNKNMFLMTGSEIVVDNALLMGAHGVVPGLANVDPAGYVRLWDAAQRGDWVAARKEQERL
CRLFEIVWVGAGRVSGGAAGVGAFKTAMRSLGIISTNKMARPRQAQNTAEAGRIDAILRSVGLLD
>Mature_304_residues
SKFFGVVPPVVTPLNDDHSVDYDSYTRVLEHLIEGGCHGLFALGSTSEVVFYDEADRRRILEHTVKVANGRVPVIAGVID
PATDRVIAHAKAAKDVGADAVVVTAPFYTITSQPEIIDHFRMVRDAVDIPLIAYDIPVCVHAKLTRQTVVTLANEGTIIG
LKDSSGDDGNFRYALLDLAKNKNMFLMTGSEIVVDNALLMGAHGVVPGLANVDPAGYVRLWDAAQRGDWVAARKEQERLC
RLFEIVWVGAGRVSGGAAGVGAFKTAMRSLGIISTNKMARPRQAQNTAEAGRIDAILRSVGLLD

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=238, Percent_Identity=30.2521008403361, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI87082415, Length=307, Percent_Identity=28.3387622149837, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788823, Length=301, Percent_Identity=24.9169435215947, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786463, Length=245, Percent_Identity=28.9795918367347, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789620, Length=279, Percent_Identity=27.5985663082437, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32876; Mature: 32745

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00445 FGGY_KINASES_2 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFFGVVPPVVTPLNDDHSVDYDSYTRVLEHLIEGGCHGLFALGSTSEVVFYDEADRRR
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCHHHHH
ILEHTVKVANGRVPVIAGVIDPATDRVIAHAKAAKDVGADAVVVTAPFYTITSQPEIIDH
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECEEEECCCCHHHHH
FRMVRDAVDIPLIAYDIPVCVHAKLTRQTVVTLANEGTIIGLKDSSGDDGNFRYALLDLA
HHHHHHHHCCCEEEEECCEEEEHHHHHEEEEEEECCCEEEEEECCCCCCCCEEEEEEEEC
KNKNMFLMTGSEIVVDNALLMGAHGVVPGLANVDPAGYVRLWDAAQRGDWVAARKEQERL
CCCCEEEEECCEEEECCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHH
CRLFEIVWVGAGRVSGGAAGVGAFKTAMRSLGIISTNKMARPRQAQNTAEAGRIDAILRS
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCHHHCCHHHHHHHHHHHHH
VGLLD
HCCCC
>Mature Secondary Structure 
SKFFGVVPPVVTPLNDDHSVDYDSYTRVLEHLIEGGCHGLFALGSTSEVVFYDEADRRR
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCHHHHH
ILEHTVKVANGRVPVIAGVIDPATDRVIAHAKAAKDVGADAVVVTAPFYTITSQPEIIDH
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECEEEECCCCHHHHH
FRMVRDAVDIPLIAYDIPVCVHAKLTRQTVVTLANEGTIIGLKDSSGDDGNFRYALLDLA
HHHHHHHHCCCEEEEECCEEEEHHHHHEEEEEEECCCEEEEEECCCCCCCCEEEEEEEEC
KNKNMFLMTGSEIVVDNALLMGAHGVVPGLANVDPAGYVRLWDAAQRGDWVAARKEQERL
CCCCEEEEECCEEEECCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHH
CRLFEIVWVGAGRVSGGAAGVGAFKTAMRSLGIISTNKMARPRQAQNTAEAGRIDAILRS
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCHHHCCHHHHHHHHHHHHH
VGLLD
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA