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The map label for this gene is CYP102A1 [H]

Identifier: 225686084

GI number: 225686084

Start: 218757

End: 220961

Strand: Direct

Name: CYP102A1 [H]

Synonym: BMEA_B0233

Alternate gene names: 225686084

Gene position: 218757-220961 (Clockwise)

Preceding gene: 225686083

Following gene: 225686085

Centisome position: 18.45

GC content: 60.45

Gene sequence:

>2205_bases
ATGATCCGCTGGTTGCATCGCTGGTCCGGTATAATAGCGGCTGTTCTTTTGATGGTGCTGGCATTGAGCGGCGCCGCCTT
GTCGGTGTTCCCGGCGATGGAGCGGCTTTCTGCGCCGCAAGCCGAAACGGGCCTTTCGGTGGCCGATCTCATGGCGCGTA
TTCAGGCCAATTATCCTGCGGTCGAGCAGGTGCGGCGTACGCCTTCTGGCAAGATTACGGCTTACTGGTTCGATGACGGC
GCGCCGCAGGCCGCCGTCATCGACCCCGCCACCGGCAAGAGTGTTGCTCCGGCAAACCCGAATAGGCTGGAACAATGGCT
GAAAGGTTTGCATCGTTCGCTCTTTCTGGGCGATAGCGGGCGCATTGTCATGGCTATCGGCGCTCTCATCATGCTGGGAC
TCAGCATATCCGGCGCATTTTTGATTGCACGCCGCACAGGCGGCTGGAAAAACTGGTTCAAGCCGCTGCGTGGGGCTGCC
AGTGGGAGGCTGCATACAGAAGTGGCGCGTATTGCGGTTTTGGGATTGCTTCTGTCTTCCACAACCGCCGTGTGGATGTC
GGCTTCGACCTTCGATCTTCTGCCCAAAAGCCCGGTTGTTGCGGAGCCAACCGGTGTGAGCGGCGAGACGGGTATGAAGC
CTGCCCTGATTGCCAAACTTGAGGAAACGCCGGTTTCCAGCTTCAAGGAGCTGAGTTTCCCTTATCCCGGTGATGCCACG
GATATGTTCGTGCTGAAGACGGACCGAGGCACCGGCTATCTGGATCAGGGTACCGGCGCAGTGTTGGACTGGCATGATTA
CACGGTCTGGCAGCGCATCTCCCAGACTGTCAAAATGCTGCATACCGGCAAGGGGGCCGCACTACTGGGCATTATTCTCG
GCCTGGCATCCCTGACGGTTCCCTTTCTGGGCATCACCGGCATCGTGTTATGGTTCGCTGGACTGCGTGGCCGCCCGCGC
ATTCGCGACAATGCCGCAGCCGGAAAGGCCGAAACAATTGTGCTGGTCGGCAGCGAAGGCGGCAGCACCTGGGGTTTTGC
CGCAACGCTTCACGCTGCTTTGCGCGAAGCGGGCCAGAGCGTTCATGTCGGCCCCATGTCTTCCTTCAACCCGGCGCGTT
ATGGCAAGGCGCAGCGCATTTTGATCTTTGCCGCCACCTATGGAAACGGTGATGCGCCCGCCTCTGCCAAGGGCTTTCTG
GATCGCCTGGCTGCCTTGCCGAAGTCGCCTGCTGCGCCTCTGGCAGTATTGGGCTTTGGCGACCGCAGTTTCCCGGATTA
TTGCGCCTTTGCAAAGGCGATAGCCGATGGAGCGCGGGCAAAGGGCTGGAAAGAGCTTATCCCGTTCGAGACGGTGGACC
GCCAGTCCACGCAGGATTTTGCCCGCTGGGGGCGGGATCTGGGCGCTGCGATTGGCATCAAGCTGGAGCTTGTCCATCAG
CCTGTCATTCCGGCGGTTGCGGCGCTGACGCTCGTTTCGCGCCGGGATTATGGCGCTGATGTGCAGGCCCCGACTGCCAT
CCTGCGTTTTGCCCTGCCGAAACCGACATTCTGGCAGCAGTTGAGCGGTGCCGGTTTCAGCCGCTTCGAGGCGGGGGATT
TGCTGGGCATCGTTCCCGAAGGTTCAGCCGTTCCGCGTTTCTATTCCCTCGCATCGGGAAGCCGCGATGGCTTTGTCGAG
ATCGTGGTGAAAAAGCATCCGGCAGGGCTTTGCTCCGGCCAGCTTTTCGAGCTTCAACCGGGCGATACCATGCGTGCCTT
CCTGCGTCGCAACGCAAATTTCCATGCCGGAAAGGGGCGCACGCCGCTGATCCTCGTCGGTGCTGGCACGGGCATCGGGC
CACTTGCGGGTATCGTGCGGGCAAACAGGCAGCATCGCCCTGTCCACCTGTTTTTCGGCATGCGCCATCCCGAAAGCGAT
TTCTTCTATCATGAGGATTTGCAGGAATGGCAAGGTGAGGGCCGTCTTCAAAACCTCACTACTGCCTGTTCGCGTGTGCA
CAATCCAAGCTATGTGCAGGACGCCTTGCGCAAGGATGCCGCCGAGATTGCGCGCCTCGTCAACAAGGGCGCACGGGTCA
TGGTCTGTGGCGGACGCGACATGGCGGCGGGTGTTTCCGAAGCCCTTGCCGATATTCTGGCTCCAGCCGGATTGACGCCT
GCCGTTCTGAAGGCGGAGGGGCGCTATGTCGAAGATGTTTACTGA

Upstream 100 bases:

>100_bases
GACGAAATCGCCCTGCCGCTGACAAGCAAGGGCAGCGGCGTCCCGGTTCGCGGACGGCGTTACATCGCCAACTTCACCTA
TACGAAATAAGGAGCTGGCC

Downstream 100 bases:

>100_bases
TCTCAAGCGCCATGGATTGAACGGCCCCACCATGCGCACGCGCTGGTCGGCAATTTTTTACGCCGCTGCCGATTTCGACA
TCGCTCCCTTGCGGCGCGCG

Product: oxidoreductase FAD-binding

Products: NA

Alternate protein names: Cytochrome P450(BM-3); Cytochrome P450BM-3; Cytochrome P450 102; NADPH--cytochrome P450 reductase [H]

Number of amino acids: Translated: 734; Mature: 734

Protein sequence:

>734_residues
MIRWLHRWSGIIAAVLLMVLALSGAALSVFPAMERLSAPQAETGLSVADLMARIQANYPAVEQVRRTPSGKITAYWFDDG
APQAAVIDPATGKSVAPANPNRLEQWLKGLHRSLFLGDSGRIVMAIGALIMLGLSISGAFLIARRTGGWKNWFKPLRGAA
SGRLHTEVARIAVLGLLLSSTTAVWMSASTFDLLPKSPVVAEPTGVSGETGMKPALIAKLEETPVSSFKELSFPYPGDAT
DMFVLKTDRGTGYLDQGTGAVLDWHDYTVWQRISQTVKMLHTGKGAALLGIILGLASLTVPFLGITGIVLWFAGLRGRPR
IRDNAAAGKAETIVLVGSEGGSTWGFAATLHAALREAGQSVHVGPMSSFNPARYGKAQRILIFAATYGNGDAPASAKGFL
DRLAALPKSPAAPLAVLGFGDRSFPDYCAFAKAIADGARAKGWKELIPFETVDRQSTQDFARWGRDLGAAIGIKLELVHQ
PVIPAVAALTLVSRRDYGADVQAPTAILRFALPKPTFWQQLSGAGFSRFEAGDLLGIVPEGSAVPRFYSLASGSRDGFVE
IVVKKHPAGLCSGQLFELQPGDTMRAFLRRNANFHAGKGRTPLILVGAGTGIGPLAGIVRANRQHRPVHLFFGMRHPESD
FFYHEDLQEWQGEGRLQNLTTACSRVHNPSYVQDALRKDAAEIARLVNKGARVMVCGGRDMAAGVSEALADILAPAGLTP
AVLKAEGRYVEDVY

Sequences:

>Translated_734_residues
MIRWLHRWSGIIAAVLLMVLALSGAALSVFPAMERLSAPQAETGLSVADLMARIQANYPAVEQVRRTPSGKITAYWFDDG
APQAAVIDPATGKSVAPANPNRLEQWLKGLHRSLFLGDSGRIVMAIGALIMLGLSISGAFLIARRTGGWKNWFKPLRGAA
SGRLHTEVARIAVLGLLLSSTTAVWMSASTFDLLPKSPVVAEPTGVSGETGMKPALIAKLEETPVSSFKELSFPYPGDAT
DMFVLKTDRGTGYLDQGTGAVLDWHDYTVWQRISQTVKMLHTGKGAALLGIILGLASLTVPFLGITGIVLWFAGLRGRPR
IRDNAAAGKAETIVLVGSEGGSTWGFAATLHAALREAGQSVHVGPMSSFNPARYGKAQRILIFAATYGNGDAPASAKGFL
DRLAALPKSPAAPLAVLGFGDRSFPDYCAFAKAIADGARAKGWKELIPFETVDRQSTQDFARWGRDLGAAIGIKLELVHQ
PVIPAVAALTLVSRRDYGADVQAPTAILRFALPKPTFWQQLSGAGFSRFEAGDLLGIVPEGSAVPRFYSLASGSRDGFVE
IVVKKHPAGLCSGQLFELQPGDTMRAFLRRNANFHAGKGRTPLILVGAGTGIGPLAGIVRANRQHRPVHLFFGMRHPESD
FFYHEDLQEWQGEGRLQNLTTACSRVHNPSYVQDALRKDAAEIARLVNKGARVMVCGGRDMAAGVSEALADILAPAGLTP
AVLKAEGRYVEDVY
>Mature_734_residues
MIRWLHRWSGIIAAVLLMVLALSGAALSVFPAMERLSAPQAETGLSVADLMARIQANYPAVEQVRRTPSGKITAYWFDDG
APQAAVIDPATGKSVAPANPNRLEQWLKGLHRSLFLGDSGRIVMAIGALIMLGLSISGAFLIARRTGGWKNWFKPLRGAA
SGRLHTEVARIAVLGLLLSSTTAVWMSASTFDLLPKSPVVAEPTGVSGETGMKPALIAKLEETPVSSFKELSFPYPGDAT
DMFVLKTDRGTGYLDQGTGAVLDWHDYTVWQRISQTVKMLHTGKGAALLGIILGLASLTVPFLGITGIVLWFAGLRGRPR
IRDNAAAGKAETIVLVGSEGGSTWGFAATLHAALREAGQSVHVGPMSSFNPARYGKAQRILIFAATYGNGDAPASAKGFL
DRLAALPKSPAAPLAVLGFGDRSFPDYCAFAKAIADGARAKGWKELIPFETVDRQSTQDFARWGRDLGAAIGIKLELVHQ
PVIPAVAALTLVSRRDYGADVQAPTAILRFALPKPTFWQQLSGAGFSRFEAGDLLGIVPEGSAVPRFYSLASGSRDGFVE
IVVKKHPAGLCSGQLFELQPGDTMRAFLRRNANFHAGKGRTPLILVGAGTGIGPLAGIVRANRQHRPVHLFFGMRHPESD
FFYHEDLQEWQGEGRLQNLTTACSRVHNPSYVQDALRKDAAEIARLVNKGARVMVCGGRDMAAGVSEALADILAPAGLTP
AVLKAEGRYVEDVY

Specific function: Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is re

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI24041029, Length=246, Percent_Identity=33.739837398374, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI40254422, Length=187, Percent_Identity=36.3636363636364, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI10835173, Length=229, Percent_Identity=30.5676855895196, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI127139033, Length=165, Percent_Identity=32.1212121212121, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI169790958, Length=173, Percent_Identity=30.635838150289, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI169790956, Length=173, Percent_Identity=30.635838150289, Blast_Score=78, Evalue=4e-14,
Organism=Escherichia coli, GI1789123, Length=220, Percent_Identity=33.1818181818182, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17554134, Length=228, Percent_Identity=30.7017543859649, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17566446, Length=183, Percent_Identity=31.1475409836066, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325305, Length=168, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6321832, Length=172, Percent_Identity=33.1395348837209, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24660907, Length=209, Percent_Identity=29.6650717703349, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24660903, Length=209, Percent_Identity=29.6650717703349, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17137192, Length=224, Percent_Identity=29.4642857142857, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24582192, Length=224, Percent_Identity=29.4642857142857, Blast_Score=74, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023206
- InterPro:   IPR001128
- InterPro:   IPR015702
- InterPro:   IPR017972
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1; PF00067 p450 [H]

EC number: =1.14.14.1; =1.6.2.4 [H]

Molecular weight: Translated: 78469; Mature: 78469

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRWLHRWSGIIAAVLLMVLALSGAALSVFPAMERLSAPQAETGLSVADLMARIQANYPA
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHCCCCH
VEQVRRTPSGKITAYWFDDGAPQAAVIDPATGKSVAPANPNRLEQWLKGLHRSLFLGDSG
HHHHHCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCC
RIVMAIGALIMLGLSISGAFLIARRTGGWKNWFKPLRGAASGRLHTEVARIAVLGLLLSS
CHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
TTAVWMSASTFDLLPKSPVVAEPTGVSGETGMKPALIAKLEETPVSSFKELSFPYPGDAT
CHHEEEECCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCC
DMFVLKTDRGTGYLDQGTGAVLDWHDYTVWQRISQTVKMLHTGKGAALLGIILGLASLTV
EEEEEEECCCCCEEECCCCCEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
PFLGITGIVLWFAGLRGRPRIRDNAAAGKAETIVLVGSEGGSTWGFAATLHAALREAGQS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCE
VHVGPMSSFNPARYGKAQRILIFAATYGNGDAPASAKGFLDRLAALPKSPAAPLAVLGFG
EEECCCCCCCCHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECC
DRSFPDYCAFAKAIADGARAKGWKELIPFETVDRQSTQDFARWGRDLGAAIGIKLELVHQ
CCCCHHHHHHHHHHHCCHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEECC
PVIPAVAALTLVSRRDYGADVQAPTAILRFALPKPTFWQQLSGAGFSRFEAGDLLGIVPE
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEECCC
GSAVPRFYSLASGSRDGFVEIVVKKHPAGLCSGQLFELQPGDTMRAFLRRNANFHAGKGR
CCCCCHHHHHCCCCCCCEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCC
TPLILVGAGTGIGPLAGIVRANRQHRPVHLFFGMRHPESDFFYHEDLQEWQGEGRLQNLT
CCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHH
TACSRVHNPSYVQDALRKDAAEIARLVNKGARVMVCGGRDMAAGVSEALADILAPAGLTP
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCH
AVLKAEGRYVEDVY
HHHCCCCCCCCCCC
>Mature Secondary Structure
MIRWLHRWSGIIAAVLLMVLALSGAALSVFPAMERLSAPQAETGLSVADLMARIQANYPA
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHCCCCH
VEQVRRTPSGKITAYWFDDGAPQAAVIDPATGKSVAPANPNRLEQWLKGLHRSLFLGDSG
HHHHHCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCC
RIVMAIGALIMLGLSISGAFLIARRTGGWKNWFKPLRGAASGRLHTEVARIAVLGLLLSS
CHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
TTAVWMSASTFDLLPKSPVVAEPTGVSGETGMKPALIAKLEETPVSSFKELSFPYPGDAT
CHHEEEECCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCCCCCCC
DMFVLKTDRGTGYLDQGTGAVLDWHDYTVWQRISQTVKMLHTGKGAALLGIILGLASLTV
EEEEEEECCCCCEEECCCCCEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
PFLGITGIVLWFAGLRGRPRIRDNAAAGKAETIVLVGSEGGSTWGFAATLHAALREAGQS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCE
VHVGPMSSFNPARYGKAQRILIFAATYGNGDAPASAKGFLDRLAALPKSPAAPLAVLGFG
EEECCCCCCCCHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECC
DRSFPDYCAFAKAIADGARAKGWKELIPFETVDRQSTQDFARWGRDLGAAIGIKLELVHQ
CCCCHHHHHHHHHHHCCHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEECC
PVIPAVAALTLVSRRDYGADVQAPTAILRFALPKPTFWQQLSGAGFSRFEAGDLLGIVPE
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEECCC
GSAVPRFYSLASGSRDGFVEIVVKKHPAGLCSGQLFELQPGDTMRAFLRRNANFHAGKGR
CCCCCHHHHHCCCCCCCEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCC
TPLILVGAGTGIGPLAGIVRANRQHRPVHLFFGMRHPESDFFYHEDLQEWQGEGRLQNLT
CCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHH
TACSRVHNPSYVQDALRKDAAEIARLVNKGARVMVCGGRDMAAGVSEALADILAPAGLTP
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCH
AVLKAEGRYVEDVY
HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544578; 1727637; 8342039; 9033595; 10051560; 11695892 [H]