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The map label for this gene is yfdE [H]

Identifier: 225686075

GI number: 225686075

Start: 211522

End: 212763

Strand: Direct

Name: yfdE [H]

Synonym: BMEA_B0224

Alternate gene names: 225686075

Gene position: 211522-212763 (Clockwise)

Preceding gene: 225686074

Following gene: 225686077

Centisome position: 17.84

GC content: 58.53

Gene sequence:

>1242_bases
ATGGGTGCTTTAACGGGATATCGCGTTCTCGATATGAGCCGTGTTCTGGCCGGGCCGTGGTGCGGTCAGATTCTGGCCGA
TCTTGGCGCGGAGGTCATCAAGATCGAACGCCCGCGCACAGGCGATGACACACGCGACTGGGGGCCGCCATGGATGAAGG
ACGAGCAGGGCAACCCGACGCGCGAAGCGTCCTATTACCAGTCGGCCAACCGGGGCAAGTTTTCGGTCGCGCTCAATATT
GCATCGCCCGAAGGGCAGGACCTGCTGCGCAAGATGGTCGCCGAATGCGATGTCCTGATCGAAAATTACAAGGCCGGATC
GCTTGCCAAATATGGCCTCGATTACGAAACGCTCTCGGCAATCAATCCGGGCCTCGTCTATTGTTCGGTCACGGGGTTTG
GACAGACCGGGCCGCGCGCGCCTGAACCTGGCTATGATTTCATCATCCAGGGTATTGGCGGGCTGATGAGCATCACCGGC
GAAAGGGATGACAAGCCGGGTGGCGGCCCGCAGAAGGTGGGTGTTGCCGTGGCCGATCTGATGACCGGCCTTTATTCGGC
CATCGCGATCGAGGCAGCGCTTCTCAGCCGCGCCAAAACGGGCAAAGGGCAGCATATCGATATGGCGCTGCTTGATGTTC
AGGTGGCGGCTCTGTGCAACCAGAGCCAGAACTATCTGGCATCGGGAAGACCGCCGGGACGATATGGCAATGCACATGCG
AATATCGTGCCCTATCAGGTCTTCCGGGCCAGTGACCGCGATTTCATTATCGCTTGCGGCAATGATGCGCAGTTTGTTTC
CCTTTGTGATGCCATCGGCTTGCCGGATCTGCCGAAAGACCCGCGTTTTACGCGCAATTCCGACCGGGTGATCCACCGCG
ATGAAATCATCGGCATTCTCGCGGCGCATTTCCTGACGGGCACGGCGGATGAGTGGATCGGCAGAATCCATCCACGTGGT
GTTCCGGTTGGCGCTATCAATGATATTGCGCGCACCCTGGACGAACCACAGGTCAAGGCGCGCAATATGCTGGTGCAGAT
TCCGCATCCTTTGAACAAGGATTTCGTCACGGTCGGCAGCCCCTTCAAGCTTTCGGGAACGCCGGTGGAATACAAGCGTG
CCGCCCCCATGCTGGGTGAACATACCGACACGCTTCTCCAGCAATTGGCGAAACTGGACGATGATAGGCTGAACGACCTC
AAGTCGCGCGGCATTATCGAGCAGTTCAACTCTGGCGAATGA

Upstream 100 bases:

>100_bases
GATTCCGTTTAAACCGGAACCGCTCTAGTCGATAGAATGTACCACTCTGAATACGTGATTATCCCTTCGGTGAAGGGATC
GCATGGCGAGGTGAATGATA

Downstream 100 bases:

>100_bases
ACTGGTCCGGGCGATACCTGCCGGGTGTCGCCCGCCGATCCACCATCCATTGCCGGTAACGGCGGGCGCGGAAAAACGCA
TCGATCTGTGAAACGGCAAG

Product: L-carnitine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MGALTGYRVLDMSRVLAGPWCGQILADLGAEVIKIERPRTGDDTRDWGPPWMKDEQGNPTREASYYQSANRGKFSVALNI
ASPEGQDLLRKMVAECDVLIENYKAGSLAKYGLDYETLSAINPGLVYCSVTGFGQTGPRAPEPGYDFIIQGIGGLMSITG
ERDDKPGGGPQKVGVAVADLMTGLYSAIAIEAALLSRAKTGKGQHIDMALLDVQVAALCNQSQNYLASGRPPGRYGNAHA
NIVPYQVFRASDRDFIIACGNDAQFVSLCDAIGLPDLPKDPRFTRNSDRVIHRDEIIGILAAHFLTGTADEWIGRIHPRG
VPVGAINDIARTLDEPQVKARNMLVQIPHPLNKDFVTVGSPFKLSGTPVEYKRAAPMLGEHTDTLLQQLAKLDDDRLNDL
KSRGIIEQFNSGE

Sequences:

>Translated_413_residues
MGALTGYRVLDMSRVLAGPWCGQILADLGAEVIKIERPRTGDDTRDWGPPWMKDEQGNPTREASYYQSANRGKFSVALNI
ASPEGQDLLRKMVAECDVLIENYKAGSLAKYGLDYETLSAINPGLVYCSVTGFGQTGPRAPEPGYDFIIQGIGGLMSITG
ERDDKPGGGPQKVGVAVADLMTGLYSAIAIEAALLSRAKTGKGQHIDMALLDVQVAALCNQSQNYLASGRPPGRYGNAHA
NIVPYQVFRASDRDFIIACGNDAQFVSLCDAIGLPDLPKDPRFTRNSDRVIHRDEIIGILAAHFLTGTADEWIGRIHPRG
VPVGAINDIARTLDEPQVKARNMLVQIPHPLNKDFVTVGSPFKLSGTPVEYKRAAPMLGEHTDTLLQQLAKLDDDRLNDL
KSRGIIEQFNSGE
>Mature_412_residues
GALTGYRVLDMSRVLAGPWCGQILADLGAEVIKIERPRTGDDTRDWGPPWMKDEQGNPTREASYYQSANRGKFSVALNIA
SPEGQDLLRKMVAECDVLIENYKAGSLAKYGLDYETLSAINPGLVYCSVTGFGQTGPRAPEPGYDFIIQGIGGLMSITGE
RDDKPGGGPQKVGVAVADLMTGLYSAIAIEAALLSRAKTGKGQHIDMALLDVQVAALCNQSQNYLASGRPPGRYGNAHAN
IVPYQVFRASDRDFIIACGNDAQFVSLCDAIGLPDLPKDPRFTRNSDRVIHRDEIIGILAAHFLTGTADEWIGRIHPRGV
PVGAINDIARTLDEPQVKARNMLVQIPHPLNKDFVTVGSPFKLSGTPVEYKRAAPMLGEHTDTLLQQLAKLDDDRLNDLK
SRGIIEQFNSGE

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=408, Percent_Identity=40.4411764705882, Blast_Score=329, Evalue=3e-90,
Organism=Homo sapiens, GI300863124, Length=434, Percent_Identity=38.0184331797235, Blast_Score=315, Evalue=5e-86,
Organism=Homo sapiens, GI300863126, Length=408, Percent_Identity=34.3137254901961, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI13376042, Length=434, Percent_Identity=34.5622119815668, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI266456254, Length=417, Percent_Identity=26.1390887290168, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI42794625, Length=412, Percent_Identity=26.2135922330097, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI266458397, Length=270, Percent_Identity=29.6296296296296, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI266458393, Length=270, Percent_Identity=29.6296296296296, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI266458395, Length=152, Percent_Identity=31.5789473684211, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI42822893, Length=152, Percent_Identity=31.5789473684211, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI87082093, Length=391, Percent_Identity=37.3401534526854, Blast_Score=261, Evalue=4e-71,
Organism=Escherichia coli, GI1788717, Length=415, Percent_Identity=30.6024096385542, Blast_Score=181, Evalue=9e-47,
Organism=Escherichia coli, GI1786222, Length=420, Percent_Identity=26.4285714285714, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32564160, Length=359, Percent_Identity=26.1838440111421, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115535051, Length=338, Percent_Identity=27.5147928994083, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648431, Length=404, Percent_Identity=43.5643564356436, Blast_Score=338, Evalue=6e-93,
Organism=Drosophila melanogaster, GI24585488, Length=317, Percent_Identity=29.3375394321767, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 44801; Mature: 44670

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGALTGYRVLDMSRVLAGPWCGQILADLGAEVIKIERPRTGDDTRDWGPPWMKDEQGNPT
CCCCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
REASYYQSANRGKFSVALNIASPEGQDLLRKMVAECDVLIENYKAGSLAKYGLDYETLSA
HHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
INPGLVYCSVTGFGQTGPRAPEPGYDFIIQGIGGLMSITGERDDKPGGGPQKVGVAVADL
CCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHH
MTGLYSAIAIEAALLSRAKTGKGQHIDMALLDVQVAALCNQSQNYLASGRPPGRYGNAHA
HHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCC
NIVPYQVFRASDRDFIIACGNDAQFVSLCDAIGLPDLPKDPRFTRNSDRVIHRDEIIGIL
CCCEEHEEECCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHH
AAHFLTGTADEWIGRIHPRGVPVGAINDIARTLDEPQVKARNMLVQIPHPLNKDFVTVGS
HHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHCCEEEECCCCCCCCEEECCC
PFKLSGTPVEYKRAAPMLGEHTDTLLQQLAKLDDDRLNDLKSRGIIEQFNSGE
CEEECCCCCHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHCCCCC
>Mature Secondary Structure 
GALTGYRVLDMSRVLAGPWCGQILADLGAEVIKIERPRTGDDTRDWGPPWMKDEQGNPT
CCCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
REASYYQSANRGKFSVALNIASPEGQDLLRKMVAECDVLIENYKAGSLAKYGLDYETLSA
HHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
INPGLVYCSVTGFGQTGPRAPEPGYDFIIQGIGGLMSITGERDDKPGGGPQKVGVAVADL
CCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHH
MTGLYSAIAIEAALLSRAKTGKGQHIDMALLDVQVAALCNQSQNYLASGRPPGRYGNAHA
HHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCC
NIVPYQVFRASDRDFIIACGNDAQFVSLCDAIGLPDLPKDPRFTRNSDRVIHRDEIIGIL
CCCEEHEEECCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHH
AAHFLTGTADEWIGRIHPRGVPVGAINDIARTLDEPQVKARNMLVQIPHPLNKDFVTVGS
HHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHCCEEEECCCCCCCCEEECCC
PFKLSGTPVEYKRAAPMLGEHTDTLLQQLAKLDDDRLNDLKSRGIIEQFNSGE
CEEECCCCCHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]