| Definition | Brucella melitensis ATCC 23457 chromosome chromosome II, complete sequence. |
|---|---|
| Accession | NC_012442 |
| Length | 1,185,518 |
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The map label for this gene is fadB1 [H]
Identifier: 225686074
GI number: 225686074
Start: 209015
End: 209776
Strand: Direct
Name: fadB1 [H]
Synonym: BMEA_B0222
Alternate gene names: 225686074
Gene position: 209015-209776 (Clockwise)
Preceding gene: 225686069
Following gene: 225686075
Centisome position: 17.63
GC content: 60.89
Gene sequence:
>762_bases GTGTCGGTCGAACGACATGCGGATGGGGTCGCAACAGTCCGGATCAACAGGCCGGAAGCGAGGAACGCGCTCAACCTGAC GACGCGCCAGCAACTGGCTGAACATTTCCGCGCCTTGTCGGGGGATGAAAGCGTGCGCGCCATCGTGCTGACGGGCGGGG AAACCTGCTTTGTGGACGGTGCCGATGTTCGCGAATTCGCTTCCGCCGGTCCCATCGAAATGTATCTTCGCCATACGGAA TATCTTTGGGATGCCATCGCTTCCTGTGCGAAGCCTGTCATCGCTGCGGTCAACGGTTATGCGCTGGGCGGGGGCTGTGA GCTTGCCATGCATTGCGACATCATCGTCGCAGGCGAGGGCGCGGTGTTTGGCCAGCCTGAAGTGAAGCTTGGCCTCATGC CGGGTGCCGGCGGCACGCAGAGGCTCATCCGTGCGGTCGGGAAATTCCAGGCCATGCGCATTGCGCTGACGGGCTGTATG GTTCCCGCAGCCGAGGCGCTGTCGATTGGCATGATCAGCGAAATGACCGCCAATGAAAGGACATTGCCGCGCGCGCATGA ACTGGCTGTGGAAATTGCGCGGCTGCCCGCGCTCGCCGTTGCGCAGATCAAGGAAGTGATGCTCGTCGGCGCCGATCTGC CGCTGGATGGCGCATTGGCGCTTGAACGAAAGGCTTTCCAGCTTCTGTTCGATTCGAAAGACCAGAAAGAGGGCGCAGCC GCTTTCCTCGAAAAACGCAAACCTGCCTATAACGGACGCTAG
Upstream 100 bases:
>100_bases AGGGCCAAATAGTTTCCCATTATCAAATCAATGAAATGAAATTTCGCTATACGAAACCAAAATTCAGGAGGAAAGATTGG CTGCTTCCGAGGATAGGTTC
Downstream 100 bases:
>100_bases GACCATGGAACGTTCGATCAATCATATTGCCATTGTCGGCGCAGGCGTGATGGGAACGGGCATTGCGCAGATTGCTGCGC AGGCCGGTCTGGTGACGCAG
Product: enoyl-CoA hydratase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 253; Mature: 252
Protein sequence:
>253_residues MSVERHADGVATVRINRPEARNALNLTTRQQLAEHFRALSGDESVRAIVLTGGETCFVDGADVREFASAGPIEMYLRHTE YLWDAIASCAKPVIAAVNGYALGGGCELAMHCDIIVAGEGAVFGQPEVKLGLMPGAGGTQRLIRAVGKFQAMRIALTGCM VPAAEALSIGMISEMTANERTLPRAHELAVEIARLPALAVAQIKEVMLVGADLPLDGALALERKAFQLLFDSKDQKEGAA AFLEKRKPAYNGR
Sequences:
>Translated_253_residues MSVERHADGVATVRINRPEARNALNLTTRQQLAEHFRALSGDESVRAIVLTGGETCFVDGADVREFASAGPIEMYLRHTE YLWDAIASCAKPVIAAVNGYALGGGCELAMHCDIIVAGEGAVFGQPEVKLGLMPGAGGTQRLIRAVGKFQAMRIALTGCM VPAAEALSIGMISEMTANERTLPRAHELAVEIARLPALAVAQIKEVMLVGADLPLDGALALERKAFQLLFDSKDQKEGAA AFLEKRKPAYNGR >Mature_252_residues SVERHADGVATVRINRPEARNALNLTTRQQLAEHFRALSGDESVRAIVLTGGETCFVDGADVREFASAGPIEMYLRHTEY LWDAIASCAKPVIAAVNGYALGGGCELAMHCDIIVAGEGAVFGQPEVKLGLMPGAGGTQRLIRAVGKFQAMRIALTGCMV PAAEALSIGMISEMTANERTLPRAHELAVEIARLPALAVAQIKEVMLVGADLPLDGALALERKAFQLLFDSKDQKEGAAA FLEKRKPAYNGR
Specific function: Could possibly oxidize fatty acids using specific components [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=246, Percent_Identity=43.0894308943089, Blast_Score=191, Evalue=6e-49, Organism=Homo sapiens, GI4502327, Length=257, Percent_Identity=34.6303501945525, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI20127408, Length=201, Percent_Identity=31.8407960199005, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI70995211, Length=226, Percent_Identity=34.5132743362832, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI68989263, Length=175, Percent_Identity=36, Blast_Score=100, Evalue=9e-22, Organism=Homo sapiens, GI31542718, Length=257, Percent_Identity=28.0155642023346, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI150378541, Length=253, Percent_Identity=30.0395256916996, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI37594471, Length=174, Percent_Identity=29.8850574712644, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI37594469, Length=174, Percent_Identity=29.8850574712644, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI157694516, Length=229, Percent_Identity=25.3275109170306, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI213417737, Length=229, Percent_Identity=25.3275109170306, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI45643119, Length=206, Percent_Identity=26.6990291262136, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI260275230, Length=206, Percent_Identity=26.6990291262136, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI260274832, Length=206, Percent_Identity=26.6990291262136, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI157694520, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI62530384, Length=178, Percent_Identity=26.4044943820225, Blast_Score=68, Evalue=7e-12, Organism=Escherichia coli, GI1787659, Length=244, Percent_Identity=43.8524590163934, Blast_Score=197, Evalue=7e-52, Organism=Escherichia coli, GI221142681, Length=259, Percent_Identity=33.2046332046332, Blast_Score=127, Evalue=8e-31, Organism=Escherichia coli, GI1787660, Length=251, Percent_Identity=36.2549800796813, Blast_Score=118, Evalue=3e-28, Organism=Escherichia coli, GI1788597, Length=259, Percent_Identity=29.3436293436293, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI1790281, Length=178, Percent_Identity=33.7078651685393, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1788682, Length=224, Percent_Identity=32.5892857142857, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI87082183, Length=252, Percent_Identity=28.968253968254, Blast_Score=91, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17554946, Length=245, Percent_Identity=44.8979591836735, Blast_Score=197, Evalue=5e-51, Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=41.3934426229508, Blast_Score=186, Evalue=7e-48, Organism=Caenorhabditis elegans, GI17540714, Length=223, Percent_Identity=31.8385650224215, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17558304, Length=208, Percent_Identity=34.6153846153846, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17536985, Length=268, Percent_Identity=26.1194029850746, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17560910, Length=253, Percent_Identity=29.2490118577075, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17508951, Length=208, Percent_Identity=34.1346153846154, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI25144276, Length=208, Percent_Identity=34.1346153846154, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17508953, Length=208, Percent_Identity=34.1346153846154, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17534483, Length=233, Percent_Identity=28.3261802575107, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17540306, Length=234, Percent_Identity=28.2051282051282, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI25144160, Length=170, Percent_Identity=30.5882352941176, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI25144157, Length=170, Percent_Identity=30.5882352941176, Blast_Score=77, Evalue=7e-15, Organism=Saccharomyces cerevisiae, GI6320241, Length=186, Percent_Identity=24.7311827956989, Blast_Score=71, Evalue=2e-13, Organism=Drosophila melanogaster, GI20129971, Length=241, Percent_Identity=43.5684647302905, Blast_Score=194, Evalue=6e-50, Organism=Drosophila melanogaster, GI24653477, Length=241, Percent_Identity=43.5684647302905, Blast_Score=194, Evalue=6e-50, Organism=Drosophila melanogaster, GI24653139, Length=251, Percent_Identity=32.6693227091633, Blast_Score=121, Evalue=4e-28, Organism=Drosophila melanogaster, GI24650670, Length=206, Percent_Identity=30.5825242718447, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI21357171, Length=196, Percent_Identity=30.6122448979592, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI28571729, Length=161, Percent_Identity=32.9192546583851, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI28571730, Length=161, Percent_Identity=32.9192546583851, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI19922422, Length=257, Percent_Identity=26.0700389105058, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24654903, Length=166, Percent_Identity=27.710843373494, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI19920382, Length=215, Percent_Identity=31.1627906976744, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI24583165, Length=174, Percent_Identity=29.3103448275862, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI19921000, Length=202, Percent_Identity=30.6930693069307, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24583077, Length=203, Percent_Identity=30.5418719211823, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24583079, Length=203, Percent_Identity=30.5418719211823, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.17 [H]
Molecular weight: Translated: 26985; Mature: 26853
Theoretical pI: Translated: 6.36; Mature: 6.36
Prosite motif: PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 5.5 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 5.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSVERHADGVATVRINRPEARNALNLTTRQQLAEHFRALSGDESVRAIVLTGGETCFVDG CCCCCCCCCEEEEEECCCCCCCHHCHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECC ADVREFASAGPIEMYLRHTEYLWDAIASCAKPVIAAVNGYALGGGCELAMHCDIIVAGEG CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEEEEEECCC AVFGQPEVKLGLMPGAGGTQRLIRAVGKFQAMRIALTGCMVPAAEALSIGMISEMTANER CEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC TLPRAHELAVEIARLPALAVAQIKEVMLVGADLPLDGALALERKAFQLLFDSKDQKEGAA CCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHH AFLEKRKPAYNGR HHHHHCCCCCCCC >Mature Secondary Structure SVERHADGVATVRINRPEARNALNLTTRQQLAEHFRALSGDESVRAIVLTGGETCFVDG CCCCCCCCEEEEEECCCCCCCHHCHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECC ADVREFASAGPIEMYLRHTEYLWDAIASCAKPVIAAVNGYALGGGCELAMHCDIIVAGEG CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEEEEEECCC AVFGQPEVKLGLMPGAGGTQRLIRAVGKFQAMRIALTGCMVPAAEALSIGMISEMTANER CEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC TLPRAHELAVEIARLPALAVAQIKEVMLVGADLPLDGALALERKAFQLLFDSKDQKEGAA CCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHH AFLEKRKPAYNGR HHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751302; 11481430 [H]