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The map label for this gene is yfhC [C]

Identifier: 225686059

GI number: 225686059

Start: 188457

End: 188930

Strand: Reverse

Name: yfhC [C]

Synonym: BMEA_B0204

Alternate gene names: 225686059

Gene position: 188930-188457 (Counterclockwise)

Preceding gene: 225686063

Following gene: 225686053

Centisome position: 15.94

GC content: 59.7

Gene sequence:

>474_bases
ATGCGAAAAGCGGCGAGCATCACAAAGGCTAACAGCGCCACGCCGATGGATATCGCGCTTGAAGAAGCGCACGCCGCCGG
TGAACGCGGCGAAGTGCCGATCGGCGCCGTTATCGTGCGCGATGGCGAAATCATCGCACGCGCGGGAAACCGCACACGAG
AGTTCAACGACGTTACCGCACATGCCGAAATACTGACAATCCGCCAAGCCGGAGAGATGCTAGGCTCGGAACGGCTGATC
GACTGCGACCTCTATGTGACGCTGGAGCCCTGCGCCATGTGCGCTGCCGCCATTTCCTTCGCCCGGATCAGGCGCCTTTA
TTATGGCGCATCCGACCCCAAGGGCGGCGGCATAGAGCATGGGGGCCGCTTTTACACGCAGCTCACATGCCATCATGCCC
CCGAAATCTATCCGGGTTTTTGCGAAGCCGACGCCCGAAAAATCCTGAAGGATTTCTTCCGCGAAAAACGCTGA

Upstream 100 bases:

>100_bases
TCCGTTCGCAAATCGGTTTCGATTTCGGGAATTATGCAGTAACAAATCACTCCATGGCTTGCGAGCGAAATTTCCCGAAC
AATACACGAAATGGGACCCC

Downstream 100 bases:

>100_bases
CTATTCAGAGTATTTTCGAGCCAAAAGTCCTTCAAACTTTGGCTGGAAATGCTCTAGTTTGGCGTACCATGGCCCGTCAT
ATAGCGCAGCGTATCGTCAC

Product: cytidine and deoxycytidylate deaminase family protein

Products: uracil; NH3

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MRKAASITKANSATPMDIALEEAHAAGERGEVPIGAVIVRDGEIIARAGNRTREFNDVTAHAEILTIRQAGEMLGSERLI
DCDLYVTLEPCAMCAAAISFARIRRLYYGASDPKGGGIEHGGRFYTQLTCHHAPEIYPGFCEADARKILKDFFREKR

Sequences:

>Translated_157_residues
MRKAASITKANSATPMDIALEEAHAAGERGEVPIGAVIVRDGEIIARAGNRTREFNDVTAHAEILTIRQAGEMLGSERLI
DCDLYVTLEPCAMCAAAISFARIRRLYYGASDPKGGGIEHGGRFYTQLTCHHAPEIYPGFCEADARKILKDFFREKR
>Mature_157_residues
MRKAASITKANSATPMDIALEEAHAAGERGEVPIGAVIVRDGEIIARAGNRTREFNDVTAHAEILTIRQAGEMLGSERLI
DCDLYVTLEPCAMCAAAISFARIRRLYYGASDPKGGGIEHGGRFYTQLTCHHAPEIYPGFCEADARKILKDFFREKR

Specific function: Mutation In This Protein Makes E.Coli Resistant To The Toxic Proteins Encoded By The Gef Gene Family. [C]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=172, Percent_Identity=28.4883720930233, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI145693172, Length=142, Percent_Identity=41.5492957746479, Blast_Score=103, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17554608, Length=107, Percent_Identity=38.3177570093458, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17541138, Length=141, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325319, Length=143, Percent_Identity=32.8671328671329, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322425, Length=158, Percent_Identity=29.746835443038, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=32.4137931034483, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.1

Molecular weight: Translated: 17241; Mature: 17241

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKAASITKANSATPMDIALEEAHAAGERGEVPIGAVIVRDGEIIARAGNRTREFNDVTA
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCEEEEECCCCCCCCCCHHH
HAEILTIRQAGEMLGSERLIDCDLYVTLEPCAMCAAAISFARIRRLYYGASDPKGGGIEH
HHHHHHHHHHHHHHCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GGRFYTQLTCHHAPEIYPGFCEADARKILKDFFREKR
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKAASITKANSATPMDIALEEAHAAGERGEVPIGAVIVRDGEIIARAGNRTREFNDVTA
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCEEEEECCCCCCCCCCHHH
HAEILTIRQAGEMLGSERLIDCDLYVTLEPCAMCAAAISFARIRRLYYGASDPKGGGIEH
HHHHHHHHHHHHHHCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GGRFYTQLTCHHAPEIYPGFCEADARKILKDFFREKR
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cytosine; H2O

Specific reaction: cytosine + H2O = uracil + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA