Click here to switch to the map view.

The map label for this gene is pabB [H]

Identifier: 225685946

GI number: 225685946

Start: 78646

End: 79815

Strand: Reverse

Name: pabB [H]

Synonym: BMEA_B0084

Alternate gene names: 225685946

Gene position: 79815-78646 (Counterclockwise)

Preceding gene: 225685947

Following gene: 225685945

Centisome position: 6.73

GC content: 59.49

Gene sequence:

>1170_bases
GTGACCCGGCCGGGGAACAAACCGCTTATTCTCTTTCGCGATGACAAGGCGGGCCGCGATGTGCTTTTCGCGGCCCCCTC
AAGGATCATCCGTGCCGATACGCCGGATGAATTTGAACCCGCATGGGAAGCGATGCAAAGGGCGCACGAAGCCGGTGAAT
GGCTCGCGGGCTATCTTTCTTATGAGGCGGGCTATCTTCTGGAACCGAAGCTGAGGCCCTTGCTGCCAGAGGGGCGCAAA
ACGCCGCTTCTGTGTTTTGGCGTGTTCGACGGCCCGTCCGATGAGCAATTGCATGTGCGTGACAGCGAAAACGCCACCTG
TCTGCGCAATCCCGTCGCGCAATGGTCGTTCGAGGACTATGCGCCGCGCTTCGAGCGGCTGTACCGGCATTTGCGCGAAG
GCGATTGCTATCAGGGCAACCTGACCTTTCCTGTGACCGCGCAATGGGGTGGCGATCCGCTCATCCTGTTCAACATGCTC
GCGAAACGCCAGCCGGTCCGCTATGCGACCTATTGCGATCTCGGCGGCCCGGTTGTTTTGTCGCGCTCGCCGGAGCTTTT
CTTCAAGGTTGACGGTGACGGATGGATCGAAACCCATCCGATGAAAGGCACCATGCCGCGCGGAGCCACGCCGGAGGAAG
ACGAGCGCAACCGTCAATTCCTGCTTAACGACCCGAAAAACCAGGCCGAAAACCGCATGATCGTGGACCTGTTGCGCAAC
GATATCTCGCTGGTGAGCGAGGTGGGGTCTCTCGACGTGCCGGAACTTTTCCGGGTCGAATCCTATCCAACCGTCCACCA
GATGGTCAGCCGCGTGCGAGCAAGGCTGAAAAGCGGATTGCATCTGCGGGCAGTTTTCGCCGCACTTTTTCCTTGCGGTT
CCATCACCGGCGCGCCCAAGATCAGCGCCATGAAAATCCTGCGCAGGCTTGAAACCGGCCCGCGCGACATCTATTGCGGC
TCGCTCGGCTGGATCGAACCGGGCGGGCGCATGCGTTTCAACGTTGCCATACGCACGATCTCGCTTCTGGGCGGAAATCG
TGCAATCTTCAATGTCGGAGGCGGTGTAGTCTTCGATTCCACGGCGCAAGCGGAGTACGAGGAATGTCTTCTGAAAGCAC
GGTTCGCGACGGGTCAAAAGCCGTTACCAGCGAACCGGATTATCAGCTGA

Upstream 100 bases:

>100_bases
TGGCCTGGATGCCTCGGACCCCGGTTTCTGGAACAAGGGACTTTCGGTGATCGAAGGCATCATCGACGAACTCGAAGCCA
TGGAAGACTGAGCAAGAACT

Downstream 100 bases:

>100_bases
TCGAAACCATGCGATGGGAGCCGCTTGCCGGCGTCCTGCGCTTCGACCTGCATATGGCCCGCCTTGAAAATTCCGCTAGG
GAATTGAATTTCGCCTGCAA

Product: aminodeoxychorismate synthase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTRPGNKPLILFRDDKAGRDVLFAAPSRIIRADTPDEFEPAWEAMQRAHEAGEWLAGYLSYEAGYLLEPKLRPLLPEGRK
TPLLCFGVFDGPSDEQLHVRDSENATCLRNPVAQWSFEDYAPRFERLYRHLREGDCYQGNLTFPVTAQWGGDPLILFNML
AKRQPVRYATYCDLGGPVVLSRSPELFFKVDGDGWIETHPMKGTMPRGATPEEDERNRQFLLNDPKNQAENRMIVDLLRN
DISLVSEVGSLDVPELFRVESYPTVHQMVSRVRARLKSGLHLRAVFAALFPCGSITGAPKISAMKILRRLETGPRDIYCG
SLGWIEPGGRMRFNVAIRTISLLGGNRAIFNVGGGVVFDSTAQAEYEECLLKARFATGQKPLPANRIIS

Sequences:

>Translated_389_residues
MTRPGNKPLILFRDDKAGRDVLFAAPSRIIRADTPDEFEPAWEAMQRAHEAGEWLAGYLSYEAGYLLEPKLRPLLPEGRK
TPLLCFGVFDGPSDEQLHVRDSENATCLRNPVAQWSFEDYAPRFERLYRHLREGDCYQGNLTFPVTAQWGGDPLILFNML
AKRQPVRYATYCDLGGPVVLSRSPELFFKVDGDGWIETHPMKGTMPRGATPEEDERNRQFLLNDPKNQAENRMIVDLLRN
DISLVSEVGSLDVPELFRVESYPTVHQMVSRVRARLKSGLHLRAVFAALFPCGSITGAPKISAMKILRRLETGPRDIYCG
SLGWIEPGGRMRFNVAIRTISLLGGNRAIFNVGGGVVFDSTAQAEYEECLLKARFATGQKPLPANRIIS
>Mature_388_residues
TRPGNKPLILFRDDKAGRDVLFAAPSRIIRADTPDEFEPAWEAMQRAHEAGEWLAGYLSYEAGYLLEPKLRPLLPEGRKT
PLLCFGVFDGPSDEQLHVRDSENATCLRNPVAQWSFEDYAPRFERLYRHLREGDCYQGNLTFPVTAQWGGDPLILFNMLA
KRQPVRYATYCDLGGPVVLSRSPELFFKVDGDGWIETHPMKGTMPRGATPEEDERNRQFLLNDPKNQAENRMIVDLLRND
ISLVSEVGSLDVPELFRVESYPTVHQMVSRVRARLKSGLHLRAVFAALFPCGSITGAPKISAMKILRRLETGPRDIYCGS
LGWIEPGGRMRFNVAIRTISLLGGNRAIFNVGGGVVFDSTAQAEYEECLLKARFATGQKPLPANRIIS

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=257, Percent_Identity=42.4124513618677, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1787518, Length=229, Percent_Identity=32.3144104803493, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786809, Length=229, Percent_Identity=24.4541484716157, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=256, Percent_Identity=33.59375, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6324361, Length=279, Percent_Identity=30.4659498207885, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 43684; Mature: 43552

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPGNKPLILFRDDKAGRDVLFAAPSRIIRADTPDEFEPAWEAMQRAHEAGEWLAGYLS
CCCCCCCCEEEEECCCCCCEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YEAGYLLEPKLRPLLPEGRKTPLLCFGVFDGPSDEQLHVRDSENATCLRNPVAQWSFEDY
HCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHCCHHCCCCHHC
APRFERLYRHLREGDCYQGNLTFPVTAQWGGDPLILFNMLAKRQPVRYATYCDLGGPVVL
CHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEE
SRSPELFFKVDGDGWIETHPMKGTMPRGATPEEDERNRQFLLNDPKNQAENRMIVDLLRN
ECCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHH
DISLVSEVGSLDVPELFRVESYPTVHQMVSRVRARLKSGLHLRAVFAALFPCGSITGAPK
HHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
ISAMKILRRLETGPRDIYCGSLGWIEPGGRMRFNVAIRTISLLGGNRAIFNVGGGVVFDS
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEEEEEEEECCCEEEEECCCCEEECC
TAQAEYEECLLKARFATGQKPLPANRIIS
CCHHHHHHHHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure 
TRPGNKPLILFRDDKAGRDVLFAAPSRIIRADTPDEFEPAWEAMQRAHEAGEWLAGYLS
CCCCCCCEEEEECCCCCCEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YEAGYLLEPKLRPLLPEGRKTPLLCFGVFDGPSDEQLHVRDSENATCLRNPVAQWSFEDY
HCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHCCHHCCCCHHC
APRFERLYRHLREGDCYQGNLTFPVTAQWGGDPLILFNMLAKRQPVRYATYCDLGGPVVL
CHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEE
SRSPELFFKVDGDGWIETHPMKGTMPRGATPEEDERNRQFLLNDPKNQAENRMIVDLLRN
ECCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHH
DISLVSEVGSLDVPELFRVESYPTVHQMVSRVRARLKSGLHLRAVFAALFPCGSITGAPK
HHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
ISAMKILRRLETGPRDIYCGSLGWIEPGGRMRFNVAIRTISLLGGNRAIFNVGGGVVFDS
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEEEEEEEECCCEEEEECCCCEEECC
TAQAEYEECLLKARFATGQKPLPANRIIS
CCHHHHHHHHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]