The gene/protein map for NC_012441 is currently unavailable.
Definition Brucella melitensis ATCC 23457 chromosome chromosome I, complete sequence.
Accession NC_012441
Length 2,125,701

Click here to switch to the map view.

The map label for this gene is aidB [C]

Identifier: 225851948

GI number: 225851948

Start: 436193

End: 437971

Strand: Reverse

Name: aidB [C]

Synonym: BMEA_A0443

Alternate gene names: 225851948

Gene position: 437971-436193 (Counterclockwise)

Preceding gene: 225851950

Following gene: 225851947

Centisome position: 20.6

GC content: 61.1

Gene sequence:

>1779_bases
ATGTATCGCGCGCCGGTTTCTGAAATTTCCCACACACTGATGAAGGTCGCGGGCCTCGAAAAAGCACTCGAAGAAAACTG
CTTCCCGGAATTCTCCGCCGATCTGGCCGCTGCCATTCTGGAAGAGGCAGGCAAATTTGCCGCCGACCGTATCGAGCCGC
TGCGCATCACCGGCGACAAGAACGGCGCTACCGTGAAGGACGGTGTCGTCACCACGGCGCCGGGCTGGAAAGAGCTTTAC
CGCGACTGGATCGCGGGCGGCTGGAATTCGCTGACCGGCACGCCGGAATATGGCGGCCAGGGCCTGCCGACCATGATGTC
GGTGGCTGTCAGCGAAATGTGGAATTCCGGCACGCTGGCCTTCGCGATTGCGCCGACGCTGACCATGGGCGCGGTCGAGG
CGCTGGAAAAGCACGCATCACGCGAATTGAAGGATATCTATCTGGAAAAGCTCATCTCCGGCGAATGGATGGGCACAATG
AACCTGACCGAACCGCAAGCGGGATCCGATCTCGGCGCGCTGCGCACCCGCGCGGAACGCCGCGACGACGGCACCTACCG
CATCTTTGGCCAGAAGATCTTCATCACCTATGGCGAACACGACCTCACCGACAATATCGTGCATCTGGTGCTGGCGCGCC
TGCCCGATGCCCCTGCGGGAACCAAGGGCATTTCGCTGTTCCTCGTGCCGAAATTCCTCGTCAATGAGGATGGTTCGCTC
GGCCGCCGCAACGATCTTTTCTGCTCCGGCCTTGAGCACAAGATGGGCATTCACGCCTCCCCCACCTGCACCATGATCTA
TGGTGACGGCTTCGTGAAAGGCGAAGAACAGGGCGCGGTCGGCTATCTGATCGGTGAGGAAAATCGCGGCCTCGCCTGCA
TGTTCACCATGATGAACAATGCCCGCCTTCTCGTCGGCATTCAGGGCGTCGGCGTTGCCGAAGCCGCCTATCAGCAGGCT
CTTGCCTATGCCAAGGAACGCAAACAGGGCCGCGCGCTCGGTGCAGATCCGAAACAGGGCATGAGCCCGATCATTGAGCA
CCCGGATGTTCAGCGCATGTTGCTGACCATGAAGGCGCTGACGCAGGTTGCCCGGTCGATCACCTATGCTTGCGCCCATG
CCATCGACATGAGCCATGTAACCGACGGTGCGGACGCGCAGTTCTGGTCGGATCGCGCCGGACTGCTGACGCCGCTCGCC
AAGAGTTTTGCCACCGATGCGGGTGTGGATGTGTCCTCGCTCGGCATCCAGATTCACGGTGGCATGGGCTTTATCGAGGA
AACCGGGGCCGCACAATTGCTGCGCGATGCCCGCATCACCCCGATCTATGAAGGCACCAACGGCATTCAGGCCATCGACC
TTGTAATGCGCAAGCTGCCGCTTCAAAAGGGCGACCATATCAAGGGCTTCCTGGCTGAACTCCAAGGCGATGCCGATAAG
GCAACCGCTTCCAACCGTGCGGAGCTGGGTGAAACCGGCGCACGCCTTTCCAAGGCCATCAGCGAGGCGCGCGAAGCGAC
TGACTGGCTGCAAAAAGCAACGGCAGAAGGGCGCGCCGAAGAAGCACTTTCCGGTGCCACACCCTATCAGCGCCTCCTGT
CGCTCACCGCTGGCGGCGCTTATCTTGCGCGTGCGGCACTTGCCGGCGACGATGCGGCACGGGCCGCGCTTTGCCGTTTC
TTTGCCGAAAACATGCTGGCCGAAGTTTCTTCGCTGAAAGACACTGTTATCACCGGCGCTGCCAGCCTTACCGCTGCAAA
ATCGGCGCTGGAGGCGTGA

Upstream 100 bases:

>100_bases
GTAATAAGCCGATAGCTCTTGTATCTGACCAGCCAATTGGACCCCGTTTTCTGCCGATGCAGCGCGGGCATGTCCCAGCA
AACAGGCTTGAGGAGGAAAG

Downstream 100 bases:

>100_bases
AAATGAGCGAACATATCCTGATCGAGCGTAAAGGGGCGGTGCAGGTCATCCGCCTCAACCGGCCTGAAAAGAAAAATGCC
ATCACGCGCGCCATGTATGC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; BCAD; SCAD [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MYRAPVSEISHTLMKVAGLEKALEENCFPEFSADLAAAILEEAGKFAADRIEPLRITGDKNGATVKDGVVTTAPGWKELY
RDWIAGGWNSLTGTPEYGGQGLPTMMSVAVSEMWNSGTLAFAIAPTLTMGAVEALEKHASRELKDIYLEKLISGEWMGTM
NLTEPQAGSDLGALRTRAERRDDGTYRIFGQKIFITYGEHDLTDNIVHLVLARLPDAPAGTKGISLFLVPKFLVNEDGSL
GRRNDLFCSGLEHKMGIHASPTCTMIYGDGFVKGEEQGAVGYLIGEENRGLACMFTMMNNARLLVGIQGVGVAEAAYQQA
LAYAKERKQGRALGADPKQGMSPIIEHPDVQRMLLTMKALTQVARSITYACAHAIDMSHVTDGADAQFWSDRAGLLTPLA
KSFATDAGVDVSSLGIQIHGGMGFIEETGAAQLLRDARITPIYEGTNGIQAIDLVMRKLPLQKGDHIKGFLAELQGDADK
ATASNRAELGETGARLSKAISEAREATDWLQKATAEGRAEEALSGATPYQRLLSLTAGGAYLARAALAGDDAARAALCRF
FAENMLAEVSSLKDTVITGAASLTAAKSALEA

Sequences:

>Translated_592_residues
MYRAPVSEISHTLMKVAGLEKALEENCFPEFSADLAAAILEEAGKFAADRIEPLRITGDKNGATVKDGVVTTAPGWKELY
RDWIAGGWNSLTGTPEYGGQGLPTMMSVAVSEMWNSGTLAFAIAPTLTMGAVEALEKHASRELKDIYLEKLISGEWMGTM
NLTEPQAGSDLGALRTRAERRDDGTYRIFGQKIFITYGEHDLTDNIVHLVLARLPDAPAGTKGISLFLVPKFLVNEDGSL
GRRNDLFCSGLEHKMGIHASPTCTMIYGDGFVKGEEQGAVGYLIGEENRGLACMFTMMNNARLLVGIQGVGVAEAAYQQA
LAYAKERKQGRALGADPKQGMSPIIEHPDVQRMLLTMKALTQVARSITYACAHAIDMSHVTDGADAQFWSDRAGLLTPLA
KSFATDAGVDVSSLGIQIHGGMGFIEETGAAQLLRDARITPIYEGTNGIQAIDLVMRKLPLQKGDHIKGFLAELQGDADK
ATASNRAELGETGARLSKAISEAREATDWLQKATAEGRAEEALSGATPYQRLLSLTAGGAYLARAALAGDDAARAALCRF
FAENMLAEVSSLKDTVITGAASLTAAKSALEA
>Mature_592_residues
MYRAPVSEISHTLMKVAGLEKALEENCFPEFSADLAAAILEEAGKFAADRIEPLRITGDKNGATVKDGVVTTAPGWKELY
RDWIAGGWNSLTGTPEYGGQGLPTMMSVAVSEMWNSGTLAFAIAPTLTMGAVEALEKHASRELKDIYLEKLISGEWMGTM
NLTEPQAGSDLGALRTRAERRDDGTYRIFGQKIFITYGEHDLTDNIVHLVLARLPDAPAGTKGISLFLVPKFLVNEDGSL
GRRNDLFCSGLEHKMGIHASPTCTMIYGDGFVKGEEQGAVGYLIGEENRGLACMFTMMNNARLLVGIQGVGVAEAAYQQA
LAYAKERKQGRALGADPKQGMSPIIEHPDVQRMLLTMKALTQVARSITYACAHAIDMSHVTDGADAQFWSDRAGLLTPLA
KSFATDAGVDVSSLGIQIHGGMGFIEETGAAQLLRDARITPIYEGTNGIQAIDLVMRKLPLQKGDHIKGFLAELQGDADK
ATASNRAELGETGARLSKAISEAREATDWLQKATAEGRAEEALSGATPYQRLLSLTAGGAYLARAALAGDDAARAALCRF
FAENMLAEVSSLKDTVITGAASLTAAKSALEA

Specific function: Has an optimum specificity for 4-carbon length fatty acyl-CoAs [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=350, Percent_Identity=28.2857142857143, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI4501859, Length=408, Percent_Identity=28.4313725490196, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=26.509186351706, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI226958414, Length=381, Percent_Identity=26.509186351706, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4557233, Length=359, Percent_Identity=29.5264623955432, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI4557235, Length=470, Percent_Identity=28.2978723404255, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI76496475, Length=470, Percent_Identity=28.2978723404255, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4557231, Length=415, Percent_Identity=29.1566265060241, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI187960098, Length=415, Percent_Identity=29.1566265060241, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI21361497, Length=427, Percent_Identity=25.9953161592506, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI7656849, Length=365, Percent_Identity=26.027397260274, Blast_Score=87, Evalue=7e-17,
Organism=Escherichia coli, GI87082384, Length=396, Percent_Identity=27.7777777777778, Blast_Score=119, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17538396, Length=458, Percent_Identity=27.7292576419214, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI86563383, Length=330, Percent_Identity=29.6969696969697, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI86563381, Length=330, Percent_Identity=29.6969696969697, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=427, Percent_Identity=27.4004683840749, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=370, Percent_Identity=29.4594594594595, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17533517, Length=452, Percent_Identity=26.5486725663717, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=425, Percent_Identity=28, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=419, Percent_Identity=27.4463007159904, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=360, Percent_Identity=27.2222222222222, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=365, Percent_Identity=27.1232876712329, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=359, Percent_Identity=27.0194986072423, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=361, Percent_Identity=24.9307479224377, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=229, Percent_Identity=27.0742358078603, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32563615, Length=235, Percent_Identity=27.2340425531915, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355753, Length=417, Percent_Identity=28.7769784172662, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI21356377, Length=359, Percent_Identity=29.8050139275766, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24646207, Length=380, Percent_Identity=27.1052631578947, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24660351, Length=316, Percent_Identity=31.6455696202532, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281363737, Length=388, Percent_Identity=26.0309278350515, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24666513, Length=361, Percent_Identity=27.4238227146814, Blast_Score=90, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 63225; Mature: 63225

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRAPVSEISHTLMKVAGLEKALEENCFPEFSADLAAAILEEAGKFAADRIEPLRITGDK
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
NGATVKDGVVTTAPGWKELYRDWIAGGWNSLTGTPEYGGQGLPTMMSVAVSEMWNSGTLA
CCCEEECCEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEE
FAIAPTLTMGAVEALEKHASRELKDIYLEKLISGEWMGTMNLTEPQAGSDLGALRTRAER
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHH
RDDGTYRIFGQKIFITYGEHDLTDNIVHLVLARLPDAPAGTKGISLFLVPKFLVNEDGSL
CCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHCCCCCC
GRRNDLFCSGLEHKMGIHASPTCTMIYGDGFVKGEEQGAVGYLIGEENRGLACMFTMMNN
CCCCCCHHCCCHHHCCCCCCCCEEEEECCCEECCCCCCCEEEEEECCCCCEEEEEEECCC
ARLLVGIQGVGVAEAAYQQALAYAKERKQGRALGADPKQGMSPIIEHPDVQRMLLTMKAL
CEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCHHCCCCHHHHHHHHHHH
TQVARSITYACAHAIDMSHVTDGADAQFWSDRAGLLTPLAKSFATDAGVDVSSLGIQIHG
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCHHHCCEEEEC
GMGFIEETGAAQLLRDARITPIYEGTNGIQAIDLVMRKLPLQKGDHIKGFLAELQGDADK
CCCCHHHCCHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHH
ATASNRAELGETGARLSKAISEAREATDWLQKATAEGRAEEALSGATPYQRLLSLTAGGA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCHH
YLARAALAGDDAARAALCRFFAENMLAEVSSLKDTVITGAASLTAAKSALEA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure
MYRAPVSEISHTLMKVAGLEKALEENCFPEFSADLAAAILEEAGKFAADRIEPLRITGDK
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
NGATVKDGVVTTAPGWKELYRDWIAGGWNSLTGTPEYGGQGLPTMMSVAVSEMWNSGTLA
CCCEEECCEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEE
FAIAPTLTMGAVEALEKHASRELKDIYLEKLISGEWMGTMNLTEPQAGSDLGALRTRAER
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHH
RDDGTYRIFGQKIFITYGEHDLTDNIVHLVLARLPDAPAGTKGISLFLVPKFLVNEDGSL
CCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHCCCCCC
GRRNDLFCSGLEHKMGIHASPTCTMIYGDGFVKGEEQGAVGYLIGEENRGLACMFTMMNN
CCCCCCHHCCCHHHCCCCCCCCEEEEECCCEECCCCCCCEEEEEECCCCCEEEEEEECCC
ARLLVGIQGVGVAEAAYQQALAYAKERKQGRALGADPKQGMSPIIEHPDVQRMLLTMKAL
CEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCHHCCCCHHHHHHHHHHH
TQVARSITYACAHAIDMSHVTDGADAQFWSDRAGLLTPLAKSFATDAGVDVSSLGIQIHG
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCHHHCCEEEEC
GMGFIEETGAAQLLRDARITPIYEGTNGIQAIDLVMRKLPLQKGDHIKGFLAELQGDADK
CCCCHHHCCHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHH
ATASNRAELGETGARLSKAISEAREATDWLQKATAEGRAEEALSGATPYQRLLSLTAGGA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCHH
YLARAALAGDDAARAALCRFFAENMLAEVSSLKDTVITGAASLTAAKSALEA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8399220; 7857927 [H]