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The map label for this gene is paaG [H]

Identifier: 225851947

GI number: 225851947

Start: 435438

End: 436190

Strand: Reverse

Name: paaG [H]

Synonym: BMEA_A0442

Alternate gene names: 225851947

Gene position: 436190-435438 (Counterclockwise)

Preceding gene: 225851948

Following gene: 225851945

Centisome position: 20.52

GC content: 60.82

Gene sequence:

>753_bases
ATGAGCGAACATATCCTGATCGAGCGTAAAGGGGCGGTGCAGGTCATCCGCCTCAACCGGCCTGAAAAGAAAAATGCCAT
CACGCGCGCCATGTATGCGGCCATGGCAAAGGCGCTCAAGGACGGCGACGCGGACGATGCCGTGCGCGCGCATGTTTTCC
TCGGTGTTCCGGGCGCTTTTTCTTCCGGCAATGACATGCAGGATTTCATGGCCGCGGCCACGGGCGACACCAGCTTCGGC
AGCGAAATTCTGGATTTCCTCATTCCGCTCGCTGAAACCAAAAAGCCGATTGTTTCAGGCGTCGATGGGCTTGCCATTGG
CGTCGGCACGACGATCCATTTTCACTGCGACCTGACCTTTGCCACGCCGCGCGCGCTGTTCCGCACGCCGTTTGTCGATC
TCGGCCTCGTGCCGGAGGCAGGCTCCAGCCTGCTTGCGCCCTTGCTGATGGGGCATCAGAAAGCCTTCGCGCTGCTGGCG
CTCGGTCATGGTTTTACGGCGGAAGCCGCGCAGGAGGCCGGTATTGTCTACCAGATCGTGGACGAAGAGGCGCTGGAAGC
GGAAGTGATGAAGGCCGCGGAAGAAATTGCCGCCAAACCGCCGCAGGCCATGCAGATCGCCCGCGCCCTGATGCGCCTTC
CCGCCGAAAACATCGCTGACCGCATTACCCGCGAAGCCAAGCATTTTGCCGAGCGGCTCACCTCCGATGAGGCCCGCGAA
GCCGTGATGGCTTTTCTCAGCCGCAAAAAATAA

Upstream 100 bases:

>100_bases
TTGCCGAAAACATGCTGGCCGAAGTTTCTTCGCTGAAAGACACTGTTATCACCGGCGCTGCCAGCCTTACCGCTGCAAAA
TCGGCGCTGGAGGCGTGAAA

Downstream 100 bases:

>100_bases
ACCCGGATGTCCTCTTTTATGGGCGCATCTTTTCCGAAAACCGGTTTCCACTTTTCGGGATGCGCCCCAAGACATCCGGG
GGCTTATGGAGGTCAGCCAA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSEHILIERKGAVQVIRLNRPEKKNAITRAMYAAMAKALKDGDADDAVRAHVFLGVPGAFSSGNDMQDFMAAATGDTSFG
SEILDFLIPLAETKKPIVSGVDGLAIGVGTTIHFHCDLTFATPRALFRTPFVDLGLVPEAGSSLLAPLLMGHQKAFALLA
LGHGFTAEAAQEAGIVYQIVDEEALEAEVMKAAEEIAAKPPQAMQIARALMRLPAENIADRITREAKHFAERLTSDEARE
AVMAFLSRKK

Sequences:

>Translated_250_residues
MSEHILIERKGAVQVIRLNRPEKKNAITRAMYAAMAKALKDGDADDAVRAHVFLGVPGAFSSGNDMQDFMAAATGDTSFG
SEILDFLIPLAETKKPIVSGVDGLAIGVGTTIHFHCDLTFATPRALFRTPFVDLGLVPEAGSSLLAPLLMGHQKAFALLA
LGHGFTAEAAQEAGIVYQIVDEEALEAEVMKAAEEIAAKPPQAMQIARALMRLPAENIADRITREAKHFAERLTSDEARE
AVMAFLSRKK
>Mature_249_residues
SEHILIERKGAVQVIRLNRPEKKNAITRAMYAAMAKALKDGDADDAVRAHVFLGVPGAFSSGNDMQDFMAAATGDTSFGS
EILDFLIPLAETKKPIVSGVDGLAIGVGTTIHFHCDLTFATPRALFRTPFVDLGLVPEAGSSLLAPLLMGHQKAFALLAL
GHGFTAEAAQEAGIVYQIVDEEALEAEVMKAAEEIAAKPPQAMQIARALMRLPAENIADRITREAKHFAERLTSDEAREA
VMAFLSRKK

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI260274832, Length=253, Percent_Identity=32.0158102766798, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI45643119, Length=253, Percent_Identity=32.0158102766798, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI260275230, Length=253, Percent_Identity=32.0158102766798, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI194097323, Length=252, Percent_Identity=28.968253968254, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI25453481, Length=251, Percent_Identity=27.4900398406374, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI51538573, Length=251, Percent_Identity=27.4900398406374, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI4757966, Length=214, Percent_Identity=29.9065420560748, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI51538581, Length=214, Percent_Identity=29.9065420560748, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4757968, Length=251, Percent_Identity=27.8884462151394, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI49355787, Length=251, Percent_Identity=27.8884462151394, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI221136756, Length=251, Percent_Identity=25.8964143426295, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI221136753, Length=251, Percent_Identity=25.8964143426295, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI221307494, Length=251, Percent_Identity=25.8964143426295, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI116235487, Length=251, Percent_Identity=24.3027888446215, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI20127408, Length=184, Percent_Identity=28.804347826087, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI68989263, Length=204, Percent_Identity=28.4313725490196, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI70995211, Length=250, Percent_Identity=25.2, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI31542718, Length=246, Percent_Identity=25.2032520325203, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI62530384, Length=262, Percent_Identity=22.9007633587786, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787660, Length=257, Percent_Identity=31.5175097276265, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=25.9842519685039, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI221142681, Length=258, Percent_Identity=28.2945736434109, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788597, Length=198, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=251, Percent_Identity=31.0756972111554, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17549921, Length=211, Percent_Identity=37.4407582938389, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17554946, Length=257, Percent_Identity=31.1284046692607, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25145438, Length=249, Percent_Identity=25.3012048192771, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17534483, Length=251, Percent_Identity=25.8964143426295, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=268, Percent_Identity=26.865671641791, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=180, Percent_Identity=29.4444444444444, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=207, Percent_Identity=24.6376811594203, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=237, Percent_Identity=22.3628691983122, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=209, Percent_Identity=26.7942583732057, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654903, Length=252, Percent_Identity=30.5555555555556, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI20129971, Length=251, Percent_Identity=26.6932270916335, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24653477, Length=251, Percent_Identity=26.6932270916335, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24653139, Length=258, Percent_Identity=25.1937984496124, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357171, Length=193, Percent_Identity=26.4248704663212, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24650670, Length=184, Percent_Identity=23.9130434782609, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920382, Length=208, Percent_Identity=25.9615384615385, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19922422, Length=250, Percent_Identity=22, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 26883; Mature: 26752

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHILIERKGAVQVIRLNRPEKKNAITRAMYAAMAKALKDGDADDAVRAHVFLGVPGAF
CCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEECCCCC
SSGNDMQDFMAAATGDTSFGSEILDFLIPLAETKKPIVSGVDGLAIGVGTTIHFHCDLTF
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEECCEEEEEEEEEE
ATPRALFRTPFVDLGLVPEAGSSLLAPLLMGHQKAFALLALGHGFTAEAAQEAGIVYQIV
CCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHCCEEEEEC
DEEALEAEVMKAAEEIAAKPPQAMQIARALMRLPAENIADRITREAKHFAERLTSDEARE
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHH
AVMAFLSRKK
HHHHHHHCCC
>Mature Secondary Structure 
SEHILIERKGAVQVIRLNRPEKKNAITRAMYAAMAKALKDGDADDAVRAHVFLGVPGAF
CCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEEECCCCC
SSGNDMQDFMAAATGDTSFGSEILDFLIPLAETKKPIVSGVDGLAIGVGTTIHFHCDLTF
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEECCEEEEEEEEEE
ATPRALFRTPFVDLGLVPEAGSSLLAPLLMGHQKAFALLALGHGFTAEAAQEAGIVYQIV
CCHHHHHHCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHCCEEEEEC
DEEALEAEVMKAAEEIAAKPPQAMQIARALMRLPAENIADRITREAKHFAERLTSDEARE
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHH
AVMAFLSRKK
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]