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The map label for this gene is prsA [H]

Identifier: 222526541

GI number: 222526541

Start: 4123396

End: 4124304

Strand: Direct

Name: prsA [H]

Synonym: Chy400_3308

Alternate gene names: 222526541

Gene position: 4123396-4124304 (Clockwise)

Preceding gene: 222526540

Following gene: 222526542

Centisome position: 78.26

GC content: 57.1

Gene sequence:

>909_bases
ATGCGTCGTCTGCTATGGTTGTTTGCGCTTCTGGTGCTGGCCGGGTGTCAGAGTGCCGTTCAGGGTCAGCAGTGGGAAAC
GGTCGATTCACCGGTCGCATTCCGGCTGGGTACACAAGTCTTCACCGTTGCCGATGTCAATGCTGAGATCAAGCGGGCGA
TTGGTGATGGGGTAGCGAATGCACTGGCCAGTGGTCAGACACGTGAGCAGGTCGAACAGATTGTGGTCGAGAATGATCTG
CGTCGCCAGATTTTCGAGCAGATGATCCAGAATGAGCTGCTGTTGCAATATGCACGCCAGCATGGGATCGGGATTGATCC
GGCAGCACTCGATGCTGAAATTGCCGCCCGCCTGCCGGCTGACGCCGACCCGGCGGAGGTGCAGGATTTGCGCAACGTGC
TGGCGCGTGAGCAGATCGTCTTTGCAGTGATTGCCCGCAACACACGCGCCGATATGGCGCGGGCACGCCATATTCTGGTT
GCCGATGAGGCTACAGCGCAGGCAACGCTGGCCGAATTGCAGGCCGGTGCCGATTTTGCAACGCTGGCTGCCCAACGTTC
GCAGGATACCGGGTCGGCGGCCAATGGCGGTGATCTGGGATGGACGCCACGTGGTGAGTTTGTGCCCCAGTTTGAAGAGG
CGATCTTCTCACTACCGCTCAATACACCGCAAATTGTGCAAACCGATTTTGGTTTTCATATTGTTGAGGTGTTGGAGCGT
GAGAGTCAGCGTCCATTTTCATCTTTCGACGATCTGCGCACACGGCGCAACGCCAGCCAGTTTTATCAAGAGACATTTGT
GCCCTGGTACGAGGAGCTACGCCGGCAAGCCGAACTGAGTGGTGAGTTGCAGATTGCTGCCGGTTTTGATCCCAATACGT
TGCCGATACCCTTCCCGGAAACACCATGA

Upstream 100 bases:

>100_bases
CGAGGCGAATGTCTATTCGCCTCGTATTTTTGCGAAGGAAGCTGCCTGAGCGGTTCTCTAGCTGGTAAGCATGTGTGCTG
TGTAAGGGGAGAAGCCGTCG

Downstream 100 bases:

>100_bases
ATAATGCCTTCTCTACCCTACTGGACGTGGCGATAGCACGTGGGTTGATCGATCCGGTATCAATGCAGGTTTTCGCTATC
GATTCGGTGTTACAATCGCC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MRRLLWLFALLVLAGCQSAVQGQQWETVDSPVAFRLGTQVFTVADVNAEIKRAIGDGVANALASGQTREQVEQIVVENDL
RRQIFEQMIQNELLLQYARQHGIGIDPAALDAEIAARLPADADPAEVQDLRNVLAREQIVFAVIARNTRADMARARHILV
ADEATAQATLAELQAGADFATLAAQRSQDTGSAANGGDLGWTPRGEFVPQFEEAIFSLPLNTPQIVQTDFGFHIVEVLER
ESQRPFSSFDDLRTRRNASQFYQETFVPWYEELRRQAELSGELQIAAGFDPNTLPIPFPETP

Sequences:

>Translated_302_residues
MRRLLWLFALLVLAGCQSAVQGQQWETVDSPVAFRLGTQVFTVADVNAEIKRAIGDGVANALASGQTREQVEQIVVENDL
RRQIFEQMIQNELLLQYARQHGIGIDPAALDAEIAARLPADADPAEVQDLRNVLAREQIVFAVIARNTRADMARARHILV
ADEATAQATLAELQAGADFATLAAQRSQDTGSAANGGDLGWTPRGEFVPQFEEAIFSLPLNTPQIVQTDFGFHIVEVLER
ESQRPFSSFDDLRTRRNASQFYQETFVPWYEELRRQAELSGELQIAAGFDPNTLPIPFPETP
>Mature_302_residues
MRRLLWLFALLVLAGCQSAVQGQQWETVDSPVAFRLGTQVFTVADVNAEIKRAIGDGVANALASGQTREQVEQIVVENDL
RRQIFEQMIQNELLLQYARQHGIGIDPAALDAEIAARLPADADPAEVQDLRNVLAREQIVFAVIARNTRADMARARHILV
ADEATAQATLAELQAGADFATLAAQRSQDTGSAANGGDLGWTPRGEFVPQFEEAIFSLPLNTPQIVQTDFGFHIVEVLER
ESQRPFSSFDDLRTRRNASQFYQETFVPWYEELRRQAELSGELQIAAGFDPNTLPIPFPETP

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=92, Percent_Identity=42.3913043478261, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17537235, Length=91, Percent_Identity=38.4615384615385, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF05698 Trigger_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 33472; Mature: 33472

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLLWLFALLVLAGCQSAVQGQQWETVDSPVAFRLGTQVFTVADVNAEIKRAIGDGVAN
CHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHCCEEEEEECCCHHHHHHHHHHHHH
ALASGQTREQVEQIVVENDLRRQIFEQMIQNELLLQYARQHGIGIDPAALDAEIAARLPA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
DADPAEVQDLRNVLAREQIVFAVIARNTRADMARARHILVADEATAQATLAELQAGADFA
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCEEEEECCHHHHHHHHHHHCCCCHH
TLAAQRSQDTGSAANGGDLGWTPRGEFVPQFEEAIFSLPLNTPQIVQTDFGFHIVEVLER
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHEECCCCHHHHHHHHH
ESQRPFSSFDDLRTRRNASQFYQETFVPWYEELRRQAELSGELQIAAGFDPNTLPIPFPE
HCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
TP
CC
>Mature Secondary Structure
MRRLLWLFALLVLAGCQSAVQGQQWETVDSPVAFRLGTQVFTVADVNAEIKRAIGDGVAN
CHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHCCEEEEEECCCHHHHHHHHHHHHH
ALASGQTREQVEQIVVENDLRRQIFEQMIQNELLLQYARQHGIGIDPAALDAEIAARLPA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
DADPAEVQDLRNVLAREQIVFAVIARNTRADMARARHILVADEATAQATLAELQAGADFA
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCEEEEECCHHHHHHHHHHHCCCCHH
TLAAQRSQDTGSAANGGDLGWTPRGEFVPQFEEAIFSLPLNTPQIVQTDFGFHIVEVLER
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHEECCCCHHHHHHHHH
ESQRPFSSFDDLRTRRNASQFYQETFVPWYEELRRQAELSGELQIAAGFDPNTLPIPFPE
HCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
TP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA