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The map label for this gene is prsA [H]

Identifier: 222526384

GI number: 222526384

Start: 3898090

End: 3899055

Strand: Direct

Name: prsA [H]

Synonym: Chy400_3150

Alternate gene names: 222526384

Gene position: 3898090-3899055 (Clockwise)

Preceding gene: 222526381

Following gene: 222526385

Centisome position: 73.98

GC content: 59.73

Gene sequence:

>966_bases
GTGAGTGTTGATGCGTTTTTTCGTCGGCTGGTGTGGTTGGGGTTGGTTGCCAGTCTGCTGTTAACCGCCTGTGGTGCGCC
ATCTGGGCCGACTGTTGCCGGTTCGCCGACGACGGGTAATCCCCAAACGCCGCCGTCGCCGGAAGCTGGAGGTACGAGTG
GTACTGTGCCGGCACCCGACGATGCAATTGCCCGAGTCGGTGAGGAGTTTATCTTGCGGCGCGATTTTGACCGGCTCTAT
TTGCCCGGTGCTGACCCACAGAACCTGATCGACCAAATGATCGATGTCGAGCTGGTTGTGCAGGCAGCCCTGGCCGAAGG
GGCAACGGTTGATGAGGCGACTATTGACAGTCAGGTTGAGCAGTTGCGTCTCGCCCAGGCTGGAGGTGATGAAGCGCAAT
TTCTGACCTTTCTCCAGGATAACAATATCGCTGACGAAGAGGAATTGCGTCGGCTGCTGCGCCGTGATTATCTGATCGAG
CAGATGTTGCTCAAGCACACTACGGCTGAGCAGGTGCGCGCCCGTCATATTCTGGTAGCGGCGACTCCGGAGGAGGCCGA
GAGCCGGAAGGCAACTGCCGAGGCGATCCTGGCCGAATTGCAGGGTGGCGCTGATTTCGCCGCGTTGGCCCGGGCACGTT
CTGATGATCCGGGATCGGCAGCGCAGGGTGGTGATCTGGGATGGGCACCGCGGGGTGTCTACGTGGAACCGTTTGAAGAA
GCGGTGTTCAGCATGCAGCCCGGTGAATTGCGCCTCGTGCAAACCGATTTTGGCTGGCATATCATTGAAGTAACCGAAGG
CCCGGAAGTGCGCTCGTTTACTGATCGGGCGCTCCTGGAGACCCAGGCCGGTCAGGAGGCATTTAGCGCGACCTTCCTGC
CCTGGGTGGCAGAGCTGCGCAGTTCGGCTGAGGCGGCAGGCAAGATTGAGATTCTGGTTGATGTCGCCACGTTGACGCAA
CAGTAG

Upstream 100 bases:

>100_bases
CAGTTCTTCATATACCCTCTCCCAAAATATGGTACGATGACCGTATGACGGCATATCAATTGTGATGTGCCAGATACCCG
GTGTGGAGAGGAGTCTATTT

Downstream 100 bases:

>100_bases
CTGCTGGGGCTTGACACTGAAGACCTGGGGTATCGCGATGCAGTCATCTCGCGATACCCTTTGTTGTTGTGGGAACTGCT
GCGCATTCTCGTTCATCATG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSVDAFFRRLVWLGLVASLLLTACGAPSGPTVAGSPTTGNPQTPPSPEAGGTSGTVPAPDDAIARVGEEFILRRDFDRLY
LPGADPQNLIDQMIDVELVVQAALAEGATVDEATIDSQVEQLRLAQAGGDEAQFLTFLQDNNIADEEELRRLLRRDYLIE
QMLLKHTTAEQVRARHILVAATPEEAESRKATAEAILAELQGGADFAALARARSDDPGSAAQGGDLGWAPRGVYVEPFEE
AVFSMQPGELRLVQTDFGWHIIEVTEGPEVRSFTDRALLETQAGQEAFSATFLPWVAELRSSAEAAGKIEILVDVATLTQ
Q

Sequences:

>Translated_321_residues
MSVDAFFRRLVWLGLVASLLLTACGAPSGPTVAGSPTTGNPQTPPSPEAGGTSGTVPAPDDAIARVGEEFILRRDFDRLY
LPGADPQNLIDQMIDVELVVQAALAEGATVDEATIDSQVEQLRLAQAGGDEAQFLTFLQDNNIADEEELRRLLRRDYLIE
QMLLKHTTAEQVRARHILVAATPEEAESRKATAEAILAELQGGADFAALARARSDDPGSAAQGGDLGWAPRGVYVEPFEE
AVFSMQPGELRLVQTDFGWHIIEVTEGPEVRSFTDRALLETQAGQEAFSATFLPWVAELRSSAEAAGKIEILVDVATLTQ
Q
>Mature_320_residues
SVDAFFRRLVWLGLVASLLLTACGAPSGPTVAGSPTTGNPQTPPSPEAGGTSGTVPAPDDAIARVGEEFILRRDFDRLYL
PGADPQNLIDQMIDVELVVQAALAEGATVDEATIDSQVEQLRLAQAGGDEAQFLTFLQDNNIADEEELRRLLRRDYLIEQ
MLLKHTTAEQVRARHILVAATPEEAESRKATAEAILAELQGGADFAALARARSDDPGSAAQGGDLGWAPRGVYVEPFEEA
VFSMQPGELRLVQTDFGWHIIEVTEGPEVRSFTDRALLETQAGQEAFSATFLPWVAELRSSAEAAGKIEILVDVATLTQQ

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=151, Percent_Identity=35.0993377483444, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF05698 Trigger_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 34537; Mature: 34406

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDAFFRRLVWLGLVASLLLTACGAPSGPTVAGSPTTGNPQTPPSPEAGGTSGTVPAPD
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
DAIARVGEEFILRRDFDRLYLPGADPQNLIDQMIDVELVVQAALAEGATVDEATIDSQVE
HHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
QLRLAQAGGDEAQFLTFLQDNNIADEEELRRLLRRDYLIEQMLLKHTTAEQVRARHILVA
HHHHHHCCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCEEEEE
ATPEEAESRKATAEAILAELQGGADFAALARARSDDPGSAAQGGDLGWAPRGVYVEPFEE
ECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCHHH
AVFSMQPGELRLVQTDFGWHIIEVTEGPEVRSFTDRALLETQAGQEAFSATFLPWVAELR
HHHCCCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SSAEAAGKIEILVDVATLTQQ
HHHHHCCCEEEEEEHHHHCCC
>Mature Secondary Structure 
SVDAFFRRLVWLGLVASLLLTACGAPSGPTVAGSPTTGNPQTPPSPEAGGTSGTVPAPD
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
DAIARVGEEFILRRDFDRLYLPGADPQNLIDQMIDVELVVQAALAEGATVDEATIDSQVE
HHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
QLRLAQAGGDEAQFLTFLQDNNIADEEELRRLLRRDYLIEQMLLKHTTAEQVRARHILVA
HHHHHHCCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCEEEEE
ATPEEAESRKATAEAILAELQGGADFAALARARSDDPGSAAQGGDLGWAPRGVYVEPFEE
ECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCHHH
AVFSMQPGELRLVQTDFGWHIIEVTEGPEVRSFTDRALLETQAGQEAFSATFLPWVAELR
HHHCCCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SSAEAAGKIEILVDVATLTQQ
HHHHHCCCEEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA