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The map label for this gene is nuoN [H]

Identifier: 222526381

GI number: 222526381

Start: 3892505

End: 3893974

Strand: Direct

Name: nuoN [H]

Synonym: Chy400_3147

Alternate gene names: 222526381

Gene position: 3892505-3893974 (Clockwise)

Preceding gene: 222526380

Following gene: 222526384

Centisome position: 73.88

GC content: 56.33

Gene sequence:

>1470_bases
ATGGATTCATTGACGATCCCGCCGGTGGATCTTACATTGATGGCGCCGCTCTTGATTGTAGTGACGTGGGCGACCGCTTT
ATTGCTGGTTGATGTGTTTTTTATCCCAACCGGGCGCAAGAAGCTAACCGGCTATCTGGCTATTGCCGGGTTGATTGTCG
CGGGTCTGGCAGGATTACCGCTCTGGGGAGTAACGGGCAATACATTCGGGGGAATGCTGCGGCTCGACCCCTTCGCCCTG
ACACTGACCTGGATCTTTTTGCTGATCGGTATCCTCAGTATCGCGATGTCGCTCGAATACCTGCCGCGCCAGGATATTGA
GCAGGGTGAATACTATCCATTGATCATGTTTGCGGTCAGTGGCATGATTCTCCTGGCCCAGGGTACCGATCTGATAGTAC
TCTTTTTGGGGATCGAGACGCTCTCGATCACGCTCTACATTCTGACCGGTTTTGCCTACCCGCGCCTGACCTCGGAAGAG
GCGGCGATGAAGTACCTGGTGCTGGGTGCGTTCGCTGCCGGTTTTTTTGTGTACGGGATTGCCCTGATTTTTGGCGCTAC
CGGTTCAACTCGCCTGAGCGAGATTGGTGCCTACGCAGCCTCACGAGGGTTGGGTGATCTGAATTTGACCCTGCTCCTGG
GTGGAGCAGCAATGGTGCTGATTGCCTTCTCGTTCAAAGTGGCATTGGCGCCGTTTCACATGTGGACACCGGATGTGTAT
CAGGGTTCACCAACGCCGGTGGCGGCATTTATGAGCGTGGGCACGAAAGGTGGTGCGCTGGCAGCGCTGGTACGTCTGTT
GTTCGAGGGCTTACCGACGCTGAACGAATACTGGCTACCGGTACTGGCCGGTCTGACTGCGCTGACGATGGTGGTGGGTA
ACCTGGGAGCAGTTGCCCAGACCAACGTCAAGCGCATGCTGGCCTACTCCAGCATCGGGCATGCCGGCTACGTCATGCTC
GGTGTGATGGTTGCCGGCGAACAGCGCGGACCAGAAGCCTTCATCTTCTACATTCTCGTGTATGCATTGAGTAATTTGGG
CGCGTTCGCTGTACTGGTCGCACTTGAGCACCAGGGTGAAGAGGCGTGGCGGCTTGACGATTTTGCCGGTCTCTATCAAC
GGCAGCCGCTGCTGGCAGTTGCCATGGCCATCTTTATGTTCTCGCTGGCCGGTGTACCACCGACTGCCGGCTTCATGGCA
AAATTCTATGCCCTTACCGCAGCCTGGGAAGGTGGCCTGCCCTGGCTGGCTCTGGTCGGTGTCTTGACAAGTGCGATTGC
GGCGTTCTTCTATCTGCGGGTCATTATTCGCATGTTCATGACCGAGCCAGAGGGTGAGCCGGCTCCCGAACTCAACCGTG
GTCTAACCATTGATATTGTAGTGGCAGCAATTGGCACAATTGCGATTGGTCTCATCCCGGCACCGGTGTTTGCCCTGGTC
GAGCAATCAATGGTTGCACTTGGGGGATAA

Upstream 100 bases:

>100_bases
CACAGTGTAGCAGCGCTGGTAGCCGATTTAATGGCGCAGGTGGCCGGGCGATAAGGCTGGCAGGTGTTCATGTCAGTAGC
CCAGGCGAGGAGGAGAAAGA

Downstream 100 bases:

>100_bases
CGCAAAGGACAGTGATAGCAGCGAGGGGCAACCGCAGTGGTTGCCCCTCTTTACTTATGTCGTTACTTTACATAAATCAG
GTTGCTGCCCTTGTCACCAC

Product: proton-translocating NADH-quinone oxidoreductase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MDSLTIPPVDLTLMAPLLIVVTWATALLLVDVFFIPTGRKKLTGYLAIAGLIVAGLAGLPLWGVTGNTFGGMLRLDPFAL
TLTWIFLLIGILSIAMSLEYLPRQDIEQGEYYPLIMFAVSGMILLAQGTDLIVLFLGIETLSITLYILTGFAYPRLTSEE
AAMKYLVLGAFAAGFFVYGIALIFGATGSTRLSEIGAYAASRGLGDLNLTLLLGGAAMVLIAFSFKVALAPFHMWTPDVY
QGSPTPVAAFMSVGTKGGALAALVRLLFEGLPTLNEYWLPVLAGLTALTMVVGNLGAVAQTNVKRMLAYSSIGHAGYVML
GVMVAGEQRGPEAFIFYILVYALSNLGAFAVLVALEHQGEEAWRLDDFAGLYQRQPLLAVAMAIFMFSLAGVPPTAGFMA
KFYALTAAWEGGLPWLALVGVLTSAIAAFFYLRVIIRMFMTEPEGEPAPELNRGLTIDIVVAAIGTIAIGLIPAPVFALV
EQSMVALGG

Sequences:

>Translated_489_residues
MDSLTIPPVDLTLMAPLLIVVTWATALLLVDVFFIPTGRKKLTGYLAIAGLIVAGLAGLPLWGVTGNTFGGMLRLDPFAL
TLTWIFLLIGILSIAMSLEYLPRQDIEQGEYYPLIMFAVSGMILLAQGTDLIVLFLGIETLSITLYILTGFAYPRLTSEE
AAMKYLVLGAFAAGFFVYGIALIFGATGSTRLSEIGAYAASRGLGDLNLTLLLGGAAMVLIAFSFKVALAPFHMWTPDVY
QGSPTPVAAFMSVGTKGGALAALVRLLFEGLPTLNEYWLPVLAGLTALTMVVGNLGAVAQTNVKRMLAYSSIGHAGYVML
GVMVAGEQRGPEAFIFYILVYALSNLGAFAVLVALEHQGEEAWRLDDFAGLYQRQPLLAVAMAIFMFSLAGVPPTAGFMA
KFYALTAAWEGGLPWLALVGVLTSAIAAFFYLRVIIRMFMTEPEGEPAPELNRGLTIDIVVAAIGTIAIGLIPAPVFALV
EQSMVALGG
>Mature_489_residues
MDSLTIPPVDLTLMAPLLIVVTWATALLLVDVFFIPTGRKKLTGYLAIAGLIVAGLAGLPLWGVTGNTFGGMLRLDPFAL
TLTWIFLLIGILSIAMSLEYLPRQDIEQGEYYPLIMFAVSGMILLAQGTDLIVLFLGIETLSITLYILTGFAYPRLTSEE
AAMKYLVLGAFAAGFFVYGIALIFGATGSTRLSEIGAYAASRGLGDLNLTLLLGGAAMVLIAFSFKVALAPFHMWTPDVY
QGSPTPVAAFMSVGTKGGALAALVRLLFEGLPTLNEYWLPVLAGLTALTMVVGNLGAVAQTNVKRMLAYSSIGHAGYVML
GVMVAGEQRGPEAFIFYILVYALSNLGAFAVLVALEHQGEEAWRLDDFAGLYQRQPLLAVAMAIFMFSLAGVPPTAGFMA
KFYALTAAWEGGLPWLALVGVLTSAIAAFFYLRVIIRMFMTEPEGEPAPELNRGLTIDIVVAAIGTIAIGLIPAPVFALV
EQSMVALGG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=398, Percent_Identity=21.105527638191, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI251831108, Length=206, Percent_Identity=27.6699029126214, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI145693160, Length=495, Percent_Identity=35.3535353535354, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1788831, Length=414, Percent_Identity=26.8115942028986, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788614, Length=396, Percent_Identity=25.5050505050505, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788613, Length=455, Percent_Identity=22.8571428571429, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788827, Length=324, Percent_Identity=24.3827160493827, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788829, Length=397, Percent_Identity=24.9370277078086, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 51990; Mature: 51990

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLTIPPVDLTLMAPLLIVVTWATALLLVDVFFIPTGRKKLTGYLAIAGLIVAGLAGLP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
LWGVTGNTFGGMLRLDPFALTLTWIFLLIGILSIAMSLEYLPRQDIEQGEYYPLIMFAVS
EECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHC
GMILLAQGTDLIVLFLGIETLSITLYILTGFAYPRLTSEEAAMKYLVLGAFAAGFFVYGI
CEEEEECCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALIFGATGSTRLSEIGAYAASRGLGDLNLTLLLGGAAMVLIAFSFKVALAPFHMWTPDVY
HHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCC
QGSPTPVAAFMSVGTKGGALAALVRLLFEGLPTLNEYWLPVLAGLTALTMVVGNLGAVAQ
CCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
TNVKRMLAYSSIGHAGYVMLGVMVAGEQRGPEAFIFYILVYALSNLGAFAVLVALEHQGE
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
EAWRLDDFAGLYQRQPLLAVAMAIFMFSLAGVPPTAGFMAKFYALTAAWEGGLPWLALVG
CHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
VLTSAIAAFFYLRVIIRMFMTEPEGEPAPELNRGLTIDIVVAAIGTIAIGLIPAPVFALV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EQSMVALGG
HHHHHHCCC
>Mature Secondary Structure
MDSLTIPPVDLTLMAPLLIVVTWATALLLVDVFFIPTGRKKLTGYLAIAGLIVAGLAGLP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
LWGVTGNTFGGMLRLDPFALTLTWIFLLIGILSIAMSLEYLPRQDIEQGEYYPLIMFAVS
EECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHC
GMILLAQGTDLIVLFLGIETLSITLYILTGFAYPRLTSEEAAMKYLVLGAFAAGFFVYGI
CEEEEECCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ALIFGATGSTRLSEIGAYAASRGLGDLNLTLLLGGAAMVLIAFSFKVALAPFHMWTPDVY
HHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCC
QGSPTPVAAFMSVGTKGGALAALVRLLFEGLPTLNEYWLPVLAGLTALTMVVGNLGAVAQ
CCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
TNVKRMLAYSSIGHAGYVMLGVMVAGEQRGPEAFIFYILVYALSNLGAFAVLVALEHQGE
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
EAWRLDDFAGLYQRQPLLAVAMAIFMFSLAGVPPTAGFMAKFYALTAAWEGGLPWLALVG
CHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
VLTSAIAAFFYLRVIIRMFMTEPEGEPAPELNRGLTIDIVVAAIGTIAIGLIPAPVFALV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EQSMVALGG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA