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The map label for this gene is macB [H]

Identifier: 222524556

GI number: 222524556

Start: 1639003

End: 1640250

Strand: Direct

Name: macB [H]

Synonym: Chy400_1280

Alternate gene names: 222524556

Gene position: 1639003-1640250 (Clockwise)

Preceding gene: 222524555

Following gene: 222524557

Centisome position: 31.11

GC content: 55.61

Gene sequence:

>1248_bases
ATGAAGCTGATAGAAGCGTTGCGGATCGCTTTCAGCAGTTTACTGGCCAATAAACTGCGCGCCATTCTGACCATGCTCGG
CATCATCATCGGGGTAGGCGCTGTCATTGCTCTCCTGGCGCTGGGTGGTGCTATTCAAACGCTGGTAACCAGCGAGTTGC
AGGGATTGGGGAGTAATCTGGTGTTTCTCTTCGCGGGAACAAATGATCCAGAGACGAACCGCCGGGTACCACCACGCCTG
ACCAATGAGGATATTGCTGCCATTGCCGATCCGCTGAATGTACCGGCAGTGGCAGCGGTTTGTGCCGAGTTCAGTCGGCG
GGCACTCACCACGTATGGCGGTGCCAGCTACGATGCATTGATCGCCGGGGTAAGTGCCAATTATCCCCAGGTACGTAATG
CCCGGGTGGCTGAAGGCACGTTCTTTGACGAACGTGCGCTTGAACTGCGCTCACGTGAGGCAGTGTTGGGGTATCGCGTC
GCCCAACGTCTCTTTCCCGACGGTGCCGATCCGGTGGGCCAGCGAATCCGGATCAACGGTATCGGGTTTCAGGTGATTGG
CGTCATGGCCGAACGCGGTGGCAGTTTCGCCTCAAACGAAGATGATCAGATCTTTGTTCCCCTGACCACAGCCCAAGACC
GTCTCTTTCCACCTGCCCAAAATGTGACCCGGCGCGTGGATGTGAGTGTGGTTTACATTCAGGCTCGTGATGAAGATAGC
ATCGATGAGTTGATCGATCAGGTTACCGCGTTGCTCCGGCAACGTAATGGGCTGACCTATCAGGACAACAATTTTACCAT
CGTCACTCAGCAAGACCTGGTAAGCTCGTTTGCGACGATTACCGGTGCAATTACCATCTTCCTTGGTGCCATTGCCGCTA
TCTCGCTGGTGGTCGGCGGGATCGGGATTATGAATATTATGCTGGTCAGTGTGACGGAGCGCACACGCGAAATTGGTTTG
CGCAAAGCGGTTGGCGCCCGGCGCAATGACATCCGGCTTCAGTTTCTGGTTGAAGCGACCGTGCTCAGTTTAATGGGCGG
TATCCTCGGCATTGGCCTGGGGTATGGATTGGCAGCGATTGGGACAGCTTTACTGGCCAATTTCTCACCGAACGCTCGCG
CTGAAGTAAGCCTCGATGCAATTCTGCTCGCAACCCTTACCTCTATCGCAGTTGGGATATTTTTTGGCCTGTACCCGGCT
GATCGCGCTGCCCGCCTCGATCCGATTGCAGCACTGCGCTATGAGTAG

Upstream 100 bases:

>100_bases
ACAGTTGTGTCTACGTCCCTGGCGTCGATGCCCGTATCGATCTCTTCAGTGGCCCACCTCCCGGTGTACGCGGACGCTAA
GCTAAACGGAGCAGGTAACG

Downstream 100 bases:

>100_bases
GAGAGTAAGGACACGCAGCATCTGCCCAGGCACGCTTCAGCCCTGCCTATTACCCGTTGGTGCGGCGACATGACGCTACA
ATCATGCTCTTTATCGCTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MKLIEALRIAFSSLLANKLRAILTMLGIIIGVGAVIALLALGGAIQTLVTSELQGLGSNLVFLFAGTNDPETNRRVPPRL
TNEDIAAIADPLNVPAVAAVCAEFSRRALTTYGGASYDALIAGVSANYPQVRNARVAEGTFFDERALELRSREAVLGYRV
AQRLFPDGADPVGQRIRINGIGFQVIGVMAERGGSFASNEDDQIFVPLTTAQDRLFPPAQNVTRRVDVSVVYIQARDEDS
IDELIDQVTALLRQRNGLTYQDNNFTIVTQQDLVSSFATITGAITIFLGAIAAISLVVGGIGIMNIMLVSVTERTREIGL
RKAVGARRNDIRLQFLVEATVLSLMGGILGIGLGYGLAAIGTALLANFSPNARAEVSLDAILLATLTSIAVGIFFGLYPA
DRAARLDPIAALRYE

Sequences:

>Translated_415_residues
MKLIEALRIAFSSLLANKLRAILTMLGIIIGVGAVIALLALGGAIQTLVTSELQGLGSNLVFLFAGTNDPETNRRVPPRL
TNEDIAAIADPLNVPAVAAVCAEFSRRALTTYGGASYDALIAGVSANYPQVRNARVAEGTFFDERALELRSREAVLGYRV
AQRLFPDGADPVGQRIRINGIGFQVIGVMAERGGSFASNEDDQIFVPLTTAQDRLFPPAQNVTRRVDVSVVYIQARDEDS
IDELIDQVTALLRQRNGLTYQDNNFTIVTQQDLVSSFATITGAITIFLGAIAAISLVVGGIGIMNIMLVSVTERTREIGL
RKAVGARRNDIRLQFLVEATVLSLMGGILGIGLGYGLAAIGTALLANFSPNARAEVSLDAILLATLTSIAVGIFFGLYPA
DRAARLDPIAALRYE
>Mature_415_residues
MKLIEALRIAFSSLLANKLRAILTMLGIIIGVGAVIALLALGGAIQTLVTSELQGLGSNLVFLFAGTNDPETNRRVPPRL
TNEDIAAIADPLNVPAVAAVCAEFSRRALTTYGGASYDALIAGVSANYPQVRNARVAEGTFFDERALELRSREAVLGYRV
AQRLFPDGADPVGQRIRINGIGFQVIGVMAERGGSFASNEDDQIFVPLTTAQDRLFPPAQNVTRRVDVSVVYIQARDEDS
IDELIDQVTALLRQRNGLTYQDNNFTIVTQQDLVSSFATITGAITIFLGAIAAISLVVGGIGIMNIMLVSVTERTREIGL
RKAVGARRNDIRLQFLVEATVLSLMGGILGIGLGYGLAAIGTALLANFSPNARAEVSLDAILLATLTSIAVGIFFGLYPA
DRAARLDPIAALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=411, Percent_Identity=35.7664233576642, Blast_Score=214, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44275; Mature: 44275

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIEALRIAFSSLLANKLRAILTMLGIIIGVGAVIALLALGGAIQTLVTSELQGLGSNL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VFLFAGTNDPETNRRVPPRLTNEDIAAIADPLNVPAVAAVCAEFSRRALTTYGGASYDAL
EEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
IAGVSANYPQVRNARVAEGTFFDERALELRSREAVLGYRVAQRLFPDGADPVGQRIRING
EECCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
IGFQVIGVMAERGGSFASNEDDQIFVPLTTAQDRLFPPAQNVTRRVDVSVVYIQARDEDS
CCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHEEEEEEEEEEECCCCC
IDELIDQVTALLRQRNGLTYQDNNFTIVTQQDLVSSFATITGAITIFLGAIAAISLVVGG
HHHHHHHHHHHHHHCCCCEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGIMNIMLVSVTERTREIGLRKAVGARRNDIRLQFLVEATVLSLMGGILGIGLGYGLAAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
GTALLANFSPNARAEVSLDAILLATLTSIAVGIFFGLYPADRAARLDPIAALRYE
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MKLIEALRIAFSSLLANKLRAILTMLGIIIGVGAVIALLALGGAIQTLVTSELQGLGSNL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VFLFAGTNDPETNRRVPPRLTNEDIAAIADPLNVPAVAAVCAEFSRRALTTYGGASYDAL
EEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
IAGVSANYPQVRNARVAEGTFFDERALELRSREAVLGYRVAQRLFPDGADPVGQRIRING
EECCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
IGFQVIGVMAERGGSFASNEDDQIFVPLTTAQDRLFPPAQNVTRRVDVSVVYIQARDEDS
CCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHEEEEEEEEEEECCCCC
IDELIDQVTALLRQRNGLTYQDNNFTIVTQQDLVSSFATITGAITIFLGAIAAISLVVGG
HHHHHHHHHHHHHHCCCCEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGIMNIMLVSVTERTREIGLRKAVGARRNDIRLQFLVEATVLSLMGGILGIGLGYGLAAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
GTALLANFSPNARAEVSLDAILLATLTSIAVGIFFGLYPADRAARLDPIAALRYE
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA