Click here to switch to the map view.

The map label for this gene is resA [H]

Identifier: 222524298

GI number: 222524298

Start: 1300025

End: 1300873

Strand: Reverse

Name: resA [H]

Synonym: Chy400_1021

Alternate gene names: 222524298

Gene position: 1300873-1300025 (Counterclockwise)

Preceding gene: 222524299

Following gene: 222524297

Centisome position: 24.69

GC content: 53.12

Gene sequence:

>849_bases
ATGTCAAATATGAACAGACCAAATTACTATAGTCTGTTGGGGATAACCCCTGATGCCGATCAGGCAGCAATTGATGCCGC
TTATGCTGAACAACGGCAGCGCTATGCACCGGAACGGGTTGCCGATCTCGATGATGAACTCCGGGCAGTGGCGCAAGAGC
GGCTACAGACCATCGAGCGAGCGTACCACGTATTACGTGATCCTGAACGGCGGCGTCAGTATGACATCAGTCAGGGTCTG
ATACCATCAACAAGCCGGCCAGTCCGTCGTGAGCTGAGCCGACGCGAGTGGCTGAGCGTATTTGCTTTTTCATTCATAGC
CGTCGCTGTGGTGGCAGGTGTGTGGATATTTACGAACCGGGAGACACTTACCGGCCAGGCGATGGGTGAGGTGAATCGTC
CGGCACCTGACTTTACAGCCCCTGAATTGCGTGGTGGTACGATAGAGCTGTCTCAATACCGGGGAAAAGTCGTTGTCCTG
AATTTTTGGGGAACCTGGTGCGAACCATGCAAGCGGGAGTTGCCGGCTTTGCAGCAAGCGTATGAGCAGTTTTCCGACCA
GGGTTTGATGGTCATCGGTGTGAACCTCACCGATGATGAGCAGGTGAATGGACAAACTATTGCCGATGTGGCTGCGTTCC
TGGCGCAGTACGGTGTTACATACCCGATTGCACTCGATACCGAGGGTACAATCACTGAAGCGTATCGGGTCTTTCCTCTA
CCCACCAGCTTCTTTATTACGCCCGATGGACAGATTCGCTATGTTCACATCGGTGAACTAACCCTCGACGATATTACAGC
TCGCTTTACCGAATTGCGAGCAGCGAGTGGTGGTCAAACATCGCAGTAA

Upstream 100 bases:

>100_bases
CCATTCCGGGAGTCGCTCCGGGACTGCAATTACAGGCTCAAATCTTGATTGACGAGTATAGTCAATAAACTATATAGCTT
TTCAGGTAAGGTATGCTACA

Downstream 100 bases:

>100_bases
TTGGTCGGTATTGAGGGTTGTAACAACGGAGAACCTGTATGGATCAGCCAGAGACCATTCTGGTCGTTGAAGATGACAGC
GGTTTGCAGGAATTGATCCG

Product: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSNMNRPNYYSLLGITPDADQAAIDAAYAEQRQRYAPERVADLDDELRAVAQERLQTIERAYHVLRDPERRRQYDISQGL
IPSTSRPVRRELSRREWLSVFAFSFIAVAVVAGVWIFTNRETLTGQAMGEVNRPAPDFTAPELRGGTIELSQYRGKVVVL
NFWGTWCEPCKRELPALQQAYEQFSDQGLMVIGVNLTDDEQVNGQTIADVAAFLAQYGVTYPIALDTEGTITEAYRVFPL
PTSFFITPDGQIRYVHIGELTLDDITARFTELRAASGGQTSQ

Sequences:

>Translated_282_residues
MSNMNRPNYYSLLGITPDADQAAIDAAYAEQRQRYAPERVADLDDELRAVAQERLQTIERAYHVLRDPERRRQYDISQGL
IPSTSRPVRRELSRREWLSVFAFSFIAVAVVAGVWIFTNRETLTGQAMGEVNRPAPDFTAPELRGGTIELSQYRGKVVVL
NFWGTWCEPCKRELPALQQAYEQFSDQGLMVIGVNLTDDEQVNGQTIADVAAFLAQYGVTYPIALDTEGTITEAYRVFPL
PTSFFITPDGQIRYVHIGELTLDDITARFTELRAASGGQTSQ
>Mature_281_residues
SNMNRPNYYSLLGITPDADQAAIDAAYAEQRQRYAPERVADLDDELRAVAQERLQTIERAYHVLRDPERRRQYDISQGLI
PSTSRPVRRELSRREWLSVFAFSFIAVAVVAGVWIFTNRETLTGQAMGEVNRPAPDFTAPELRGGTIELSQYRGKVVVLN
FWGTWCEPCKRELPALQQAYEQFSDQGLMVIGVNLTDDEQVNGQTIADVAAFLAQYGVTYPIALDTEGTITEAYRVFPLP
TSFFITPDGQIRYVHIGELTLDDITARFTELRAASGGQTSQ

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=109, Percent_Identity=35.7798165137615, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 31736; Mature: 31605

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00194 THIOREDOXIN ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNMNRPNYYSLLGITPDADQAAIDAAYAEQRQRYAPERVADLDDELRAVAQERLQTIER
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHH
AYHVLRDPERRRQYDISQGLIPSTSRPVRRELSRREWLSVFAFSFIAVAVVAGVWIFTNR
HHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
ETLTGQAMGEVNRPAPDFTAPELRGGTIELSQYRGKVVVLNFWGTWCEPCKRELPALQQA
CHHCHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHH
YEQFSDQGLMVIGVNLTDDEQVNGQTIADVAAFLAQYGVTYPIALDTEGTITEAYRVFPL
HHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHEEEEEC
PTSFFITPDGQIRYVHIGELTLDDITARFTELRAASGGQTSQ
CCEEEECCCCCEEEEEECCEEHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SNMNRPNYYSLLGITPDADQAAIDAAYAEQRQRYAPERVADLDDELRAVAQERLQTIER
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHH
AYHVLRDPERRRQYDISQGLIPSTSRPVRRELSRREWLSVFAFSFIAVAVVAGVWIFTNR
HHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
ETLTGQAMGEVNRPAPDFTAPELRGGTIELSQYRGKVVVLNFWGTWCEPCKRELPALQQA
CHHCHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHH
YEQFSDQGLMVIGVNLTDDEQVNGQTIADVAAFLAQYGVTYPIALDTEGTITEAYRVFPL
HHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHEEEEEC
PTSFFITPDGQIRYVHIGELTLDDITARFTELRAASGGQTSQ
CCEEEECCCCCEEEEEECCEEHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA