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The map label for this gene is ycbL [H]

Identifier: 222524297

GI number: 222524297

Start: 1299303

End: 1299986

Strand: Reverse

Name: ycbL [H]

Synonym: Chy400_1020

Alternate gene names: 222524297

Gene position: 1299986-1299303 (Counterclockwise)

Preceding gene: 222524298

Following gene: 222524291

Centisome position: 24.67

GC content: 50.29

Gene sequence:

>684_bases
ATGGATCAGCCAGAGACCATTCTGGTCGTTGAAGATGACAGCGGTTTGCAGGAATTGATCCGGGTCCGCCTTGAACAGGA
AGGGTATCACGTTATCCAGACCATCAGTGGTCTGGAAGCAATTAAGATTATCCGACAGCAACGACCTGATCTGGTCATTC
TCGATATTATGTTACCCGACCTCGATGGGTTGACGGTTTGTCAAAAGGTGCGTGAATTTGCCTCGTTACCCATTTTGATG
CTGACCGCCAGGACGATGCCCGAAGATATTATTACCGGGCTTAATCAAGGTGCCGATGACTATGTGATCAAACCGTTCAA
TTACGACGAACTGCTGGCCCGGATTCGTGCTTTACTACGGCGGGTACCTGCAACCAATCGCCCACTCACGGTTGGCAATA
ACCTGATAAGCATTGATCAGCGGAAACGAGAAGTGCGTGTACGGGGTGAACTGGTTGATCTCACCCCAACCGAGTATCAA
TTGCTTCTAGTACTGGCTGAGCACGCTGGCGAGGTTGTAACACACGAGCAATTGCTAAGGGCTGTATGGGGTAGTGAGCC
GATGCGCGATAACGATTATCTCAAGGTATATATCTGGCATTTGCGGCGCAAGATTGAGATCGATCCGCGCCAGCCTCAGC
TTTTGTTAACCGAATGGGGAGTCGGGTATCGAATGGAACCCTGA

Upstream 100 bases:

>100_bases
ACGATATTACAGCTCGCTTTACCGAATTGCGAGCAGCGAGTGGTGGTCAAACATCGCAGTAATTGGTCGGTATTGAGGGT
TGTAACAACGGAGAACCTGT

Downstream 100 bases:

>100_bases
TTGACAGACAACGATGAACATGCTATACTTTAGCGTGCTGATGAGGTGCGGGAGTAACTCAGTTGGTAGAGTGTGTGCTT
CCCAAGCACAATGTCGCGGG

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MDQPETILVVEDDSGLQELIRVRLEQEGYHVIQTISGLEAIKIIRQQRPDLVILDIMLPDLDGLTVCQKVREFASLPILM
LTARTMPEDIITGLNQGADDYVIKPFNYDELLARIRALLRRVPATNRPLTVGNNLISIDQRKREVRVRGELVDLTPTEYQ
LLLVLAEHAGEVVTHEQLLRAVWGSEPMRDNDYLKVYIWHLRRKIEIDPRQPQLLLTEWGVGYRMEP

Sequences:

>Translated_227_residues
MDQPETILVVEDDSGLQELIRVRLEQEGYHVIQTISGLEAIKIIRQQRPDLVILDIMLPDLDGLTVCQKVREFASLPILM
LTARTMPEDIITGLNQGADDYVIKPFNYDELLARIRALLRRVPATNRPLTVGNNLISIDQRKREVRVRGELVDLTPTEYQ
LLLVLAEHAGEVVTHEQLLRAVWGSEPMRDNDYLKVYIWHLRRKIEIDPRQPQLLLTEWGVGYRMEP
>Mature_227_residues
MDQPETILVVEDDSGLQELIRVRLEQEGYHVIQTISGLEAIKIIRQQRPDLVILDIMLPDLDGLTVCQKVREFASLPILM
LTARTMPEDIITGLNQGADDYVIKPFNYDELLARIRALLRRVPATNRPLTVGNNLISIDQRKREVRVRGELVDLTPTEYQ
LLLVLAEHAGEVVTHEQLLRAVWGSEPMRDNDYLKVYIWHLRRKIEIDPRQPQLLLTEWGVGYRMEP

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=39.3665158371041, Blast_Score=167, Evalue=4e-43,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=35.7466063348416, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=35.1598173515982, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=34.6153846153846, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=33.7837837837838, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=36.322869955157, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=33.6283185840708, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1790552, Length=203, Percent_Identity=40.3940886699507, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=33.4801762114537, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=34.5132743362832, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1790863, Length=241, Percent_Identity=31.1203319502075, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=34.3612334801762, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=32.579185520362, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=29.2372881355932, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790437, Length=183, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=31.1320754716981, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=134, Percent_Identity=26.865671641791, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788191, Length=125, Percent_Identity=28.8, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1788905, Length=126, Percent_Identity=32.5396825396825, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=119, Percent_Identity=39.4957983193277, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26221; Mature: 26221

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQPETILVVEDDSGLQELIRVRLEQEGYHVIQTISGLEAIKIIRQQRPDLVILDIMLPD
CCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
LDGLTVCQKVREFASLPILMLTARTMPEDIITGLNQGADDYVIKPFNYDELLARIRALLR
CCHHHHHHHHHHHHCCCEEEEEHHCCCHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHH
RVPATNRPLTVGNNLISIDQRKREVRVRGELVDLTPTEYQLLLVLAEHAGEVVTHEQLLR
HCCCCCCCEEECCCEEECHHHHHHHEECCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
AVWGSEPMRDNDYLKVYIWHLRRKIEIDPRQPQLLLTEWGVGYRMEP
HHHCCCCCCCCCEEEEEEEEHHHHCCCCCCCCEEEEEECCCCEEECC
>Mature Secondary Structure
MDQPETILVVEDDSGLQELIRVRLEQEGYHVIQTISGLEAIKIIRQQRPDLVILDIMLPD
CCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
LDGLTVCQKVREFASLPILMLTARTMPEDIITGLNQGADDYVIKPFNYDELLARIRALLR
CCHHHHHHHHHHHHCCCEEEEEHHCCCHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHH
RVPATNRPLTVGNNLISIDQRKREVRVRGELVDLTPTEYQLLLVLAEHAGEVVTHEQLLR
HCCCCCCCEEECCCEEECHHHHHHHEECCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
AVWGSEPMRDNDYLKVYIWHLRRKIEIDPRQPQLLLTEWGVGYRMEP
HHHCCCCCCCCCEEEEEEEEHHHHCCCCCCCCEEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]