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The map label for this gene is lspA [H]

Identifier: 222524259

GI number: 222524259

Start: 1256342

End: 1256926

Strand: Reverse

Name: lspA [H]

Synonym: Chy400_0982

Alternate gene names: 222524259

Gene position: 1256926-1256342 (Counterclockwise)

Preceding gene: 222524260

Following gene: 222524258

Centisome position: 23.86

GC content: 53.68

Gene sequence:

>585_bases
ATGATGATACTACGCTCGCGCTGGATGCTGCTGGTATTGGTGGCGATACCGGTTTTTGTGATCGATCAGTTGAGTAAGGT
CTGGCTCAGTGATGTGCTCTTGCGCTACAACCGACCCATTCCCTTGCTGTTTGATTGGGTGCAACTGGCGTATCACGAAA
ATACCGGTGTCGCTTTTGGCCTGTTTCCCGATCAGGGAGGGGTTCTTTCGGTCGGGGCCGGTCTGGTGCTCTTGTTGCTT
GCGCTCACATACCAGTATATCCTTCCAGCCGACTCGCGTTGGATAACGGTAGCGGTTGGGATGATCTTTGGCGGTGGTTT
GTCCAATCTGGTAGATCGGATTCGCCAGGGCTACGTGGTCGATTTTATTCAATTTGGCTGGTGGCCGGTCTTTAACCTTG
CCGACAGCGCAATTACCATCGGGGTCGCCGCATTGGCTTTTCATATTATCTTTATCGGTGAAGAGCCGGCGCCAACCGAA
CCAGAACCGATTGACGATGAACTCCTCAGTGAGTTGTTGAGTCGCGATCCCTCGCCCCCCGCAGCAACCGATGCGCGTAC
TTCCAGTTCGGAGTCGCTATCATGA

Upstream 100 bases:

>100_bases
TTGCCGATAGTGCGATCACGGTGGGGGCAGCCCTCTTGATGTTGCAGTATGCACTTGATGAGATTGCATTGCGCCGGGTT
CGACAGGCGATGATGTCACA

Downstream 100 bases:

>100_bases
GCGGAGAAGGTGAGATTGAATTGCTCGAAGCGGAGGAGCGGGTGGTAGTTGTACCGCCAACCCAGACCGCTGAGCGTATT
GATCGCTTTCTTGCCGGTGC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MMILRSRWMLLVLVAIPVFVIDQLSKVWLSDVLLRYNRPIPLLFDWVQLAYHENTGVAFGLFPDQGGVLSVGAGLVLLLL
ALTYQYILPADSRWITVAVGMIFGGGLSNLVDRIRQGYVVDFIQFGWWPVFNLADSAITIGVAALAFHIIFIGEEPAPTE
PEPIDDELLSELLSRDPSPPAATDARTSSSESLS

Sequences:

>Translated_194_residues
MMILRSRWMLLVLVAIPVFVIDQLSKVWLSDVLLRYNRPIPLLFDWVQLAYHENTGVAFGLFPDQGGVLSVGAGLVLLLL
ALTYQYILPADSRWITVAVGMIFGGGLSNLVDRIRQGYVVDFIQFGWWPVFNLADSAITIGVAALAFHIIFIGEEPAPTE
PEPIDDELLSELLSRDPSPPAATDARTSSSESLS
>Mature_194_residues
MMILRSRWMLLVLVAIPVFVIDQLSKVWLSDVLLRYNRPIPLLFDWVQLAYHENTGVAFGLFPDQGGVLSVGAGLVLLLL
ALTYQYILPADSRWITVAVGMIFGGGLSNLVDRIRQGYVVDFIQFGWWPVFNLADSAITIGVAALAFHIIFIGEEPAPTE
PEPIDDELLSELLSRDPSPPAATDARTSSSESLS

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=166, Percent_Identity=34.3373493975904, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 21371; Mature: 21371

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMILRSRWMLLVLVAIPVFVIDQLSKVWLSDVLLRYNRPIPLLFDWVQLAYHENTGVAFG
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEE
LFPDQGGVLSVGAGLVLLLLALTYQYILPADSRWITVAVGMIFGGGLSNLVDRIRQGYVV
ECCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCHHHHHHHHHCCHHH
DFIQFGWWPVFNLADSAITIGVAALAFHIIFIGEEPAPTEPEPIDDELLSELLSRDPSPP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHCCCCCC
AATDARTSSSESLS
CCCCCCCCCCCCCC
>Mature Secondary Structure
MMILRSRWMLLVLVAIPVFVIDQLSKVWLSDVLLRYNRPIPLLFDWVQLAYHENTGVAFG
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEE
LFPDQGGVLSVGAGLVLLLLALTYQYILPADSRWITVAVGMIFGGGLSNLVDRIRQGYVV
ECCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHCCCHHHHHHHHHCCHHH
DFIQFGWWPVFNLADSAITIGVAALAFHIIFIGEEPAPTEPEPIDDELLSELLSRDPSPP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHCCCCCC
AATDARTSSSESLS
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA