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The map label for this gene is lspA [H]

Identifier: 222524260

GI number: 222524260

Start: 1256923

End: 1257432

Strand: Reverse

Name: lspA [H]

Synonym: Chy400_0983

Alternate gene names: 222524260

Gene position: 1257432-1256923 (Counterclockwise)

Preceding gene: 222524262

Following gene: 222524259

Centisome position: 23.86

GC content: 49.41

Gene sequence:

>510_bases
GTGAAATCACTGGTGCAGGCCCGCTGGATAACGCCCATACTGGTTGCAATTATCGCCGTCGCGCTGGATCAGGCGTCAAA
ACGCTGGATCGTTGCAACCCTTGGCCCTGAACCAATGACGAAATTTATTCCGTTGATTGGTGAAGATATTCGGTTGGCCT
ATTCGCATAATACTGGGATTGCGTTCAGCCTGTTTCAAGGCAAGTCGGATATTTTGACCATCGTTGCTCTGGTCATTATT
ACCGGCGCCATCTATCTCTACATCACTCAATTACCAAACCGACGGCGATTGATTCAGATCGCGATGGGTCTCATTCTTGG
TGGTGCGCTGGGAAATGTCATTGATCGTATCCGGCTTGGTTATGTGGTCGATTTTATTCAAGTTGGCTGGTTTCCGATCT
TCAATCTTGCCGATAGTGCGATCACGGTGGGGGCAGCCCTCTTGATGTTGCAGTATGCACTTGATGAGATTGCATTGCGC
CGGGTTCGACAGGCGATGATGTCACAATGA

Upstream 100 bases:

>100_bases
CGGAGAGCGGTTGTTACATGCCCTGTGTTTCACGCCCCGTTTCTAAGCTACTACGTTATAATAAACAGTAGTTAAGCAAC
GTACACGAGGAGGTTATTGC

Downstream 100 bases:

>100_bases
TGATACTACGCTCGCGCTGGATGCTGCTGGTATTGGTGGCGATACCGGTTTTTGTGATCGATCAGTTGAGTAAGGTCTGG
CTCAGTGATGTGCTCTTGCG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MKSLVQARWITPILVAIIAVALDQASKRWIVATLGPEPMTKFIPLIGEDIRLAYSHNTGIAFSLFQGKSDILTIVALVII
TGAIYLYITQLPNRRRLIQIAMGLILGGALGNVIDRIRLGYVVDFIQVGWFPIFNLADSAITVGAALLMLQYALDEIALR
RVRQAMMSQ

Sequences:

>Translated_169_residues
MKSLVQARWITPILVAIIAVALDQASKRWIVATLGPEPMTKFIPLIGEDIRLAYSHNTGIAFSLFQGKSDILTIVALVII
TGAIYLYITQLPNRRRLIQIAMGLILGGALGNVIDRIRLGYVVDFIQVGWFPIFNLADSAITVGAALLMLQYALDEIALR
RVRQAMMSQ
>Mature_169_residues
MKSLVQARWITPILVAIIAVALDQASKRWIVATLGPEPMTKFIPLIGEDIRLAYSHNTGIAFSLFQGKSDILTIVALVII
TGAIYLYITQLPNRRRLIQIAMGLILGGALGNVIDRIRLGYVVDFIQVGWFPIFNLADSAITVGAALLMLQYALDEIALR
RVRQAMMSQ

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=153, Percent_Identity=35.9477124183007, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18665; Mature: 18665

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLVQARWITPILVAIIAVALDQASKRWIVATLGPEPMTKFIPLIGEDIRLAYSHNTGI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCEEEEEECCCCE
AFSLFQGKSDILTIVALVIITGAIYLYITQLPNRRRLIQIAMGLILGGALGNVIDRIRLG
EEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVVDFIQVGWFPIFNLADSAITVGAALLMLQYALDEIALRRVRQAMMSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSLVQARWITPILVAIIAVALDQASKRWIVATLGPEPMTKFIPLIGEDIRLAYSHNTGI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCEEEEEECCCCE
AFSLFQGKSDILTIVALVIITGAIYLYITQLPNRRRLIQIAMGLILGGALGNVIDRIRLG
EEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVVDFIQVGWFPIFNLADSAITVGAALLMLQYALDEIALRRVRQAMMSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA