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The map label for this gene is baeS [H]

Identifier: 222524228

GI number: 222524228

Start: 1208063

End: 1209463

Strand: Reverse

Name: baeS [H]

Synonym: Chy400_0950

Alternate gene names: 222524228

Gene position: 1209463-1208063 (Counterclockwise)

Preceding gene: 222524229

Following gene: 222524227

Centisome position: 22.95

GC content: 60.24

Gene sequence:

>1401_bases
ATGCGCCCGCCTCGCCTCTTCAACCTGATGCTCACCGCCTTCGCCCTGGTCATCGTGCTCGGTATCAGCGGGATGGCACT
TGCGTTCTGGCTGGTCGTGGGCCAGAGCAACCCCGAACAGATGCGCTGGATGGAGGCCGAGGCAGCCGCACGTACTCAGG
CCGCTCAGCTTGCCGCCTACTATCAGCGTGTCGGTTCGTGGCGCGGGGTTGAACGTCAGTTGGGGCCACTTCCCCAGGGC
TTCGGGAGTATTGAAGGAGCAGTATCTCTGCTCGACGAGAACGGGCGTGTCGTAGCCGGTCGCCGGCGTCCGATGATCTT
GCGTGGTAACGAAGCTGTACTGCGTATACCGATTGTTGTCAATAATCAGCAAGTCGGCACTCTGGTAATCTCGGTGATAG
ATACCGATGAAGCTTTTCCGGTTGGCAACCTGAACCGCCGCCCGCTCTTGCTGGGTATGCTCAGTGCCGGAGCCGGACTG
ATGGCGGTCCTACTGGTGCTGGCAGCAATCTTCTCGCGTCAGATCAGCACCCCCTTGCGCCAGATCAGCGCAGCGGCCCA
CGCTATTGCTGACGGGGATCATAGCAGCCGGGTACAAACCGCCAATGTGCGCGAACTGGCCGATCTCTCTGCCAGCTTCA
ACCGTATGGCCGAGGCGTTGCAACAAGCCGATCAGCAACGTCGCCAGCTTACCGCCGATATTGCGCACGAATTGCGCACG
CCACTCTCGATCATCAAAGGTCGTCTCGAAGGGATTCAAGATGGCGTGTACGAAGCTGACGCCGAACAGATTGAGGCACT
CCTGACCGAGGTGGCCCTGCTTGAACGCCTCATCAACGATCTCCATCTGCTGGCCCTGGCCGATGCCGGTCAACTGCCTC
TCTACCGCGAAGTCGTATCGCCGCAGATGCTGGTCAACGAAGCGATCCGCTCATTCACCCCCGCAGCCAACGAGCGCAAT
GTGCGGCTGAGCGCTACGATTGACGACAATCTCCCTGACATTGAAGTCGATCCCCAGCGTATCGCCCAGGTGCTGGGCAA
TCTCATCGGAAATGCGCTCCGCCACACCCCGGCGGGCGGAGAGGTGATCGTAAGCGCCCACCGTGATGAGAGCGGCATTC
GTTTCGAGGTGCGTGATACCGGCGCCGGCATTGATCCTGCCGACTTACCGTACATCTTCGACCGCTTCTACAAGGCAGAT
CGGGCCCGCAGTCGGAGCAGCGGCGGTGCCGGTCTGGGGCTGGCAATTGCTCGCCGTCTGGTCGAAGCGCACGGCGGCCA
GATTTGGGCAACCAGTGCATTACAGCAGGGTACAACGGTGAGTTTCCGGTTGCCGGTATCACCAACTGCACCTGAACCGG
CGAACCAACTATCTACAGGAGCACTGCTCAACAACATTTGA

Upstream 100 bases:

>100_bases
CCGACTCGAATGGGCCACCACGCCTGATCTTGACCGTCTACGGAGTTGGCTACAAGTTTGCCGAAACGTATCCATAATCC
GATGCTCATTGAGGTGCGAT

Downstream 100 bases:

>100_bases
CATACCTGCTCAATCGTAACAAAAAACCTGACCTGAATCGGCAGCATCCTTTGGCACGTCTGATATACTGCTCACGTTTA
TCGCGACGTCTCCCAAACAT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MRPPRLFNLMLTAFALVIVLGISGMALAFWLVVGQSNPEQMRWMEAEAAARTQAAQLAAYYQRVGSWRGVERQLGPLPQG
FGSIEGAVSLLDENGRVVAGRRRPMILRGNEAVLRIPIVVNNQQVGTLVISVIDTDEAFPVGNLNRRPLLLGMLSAGAGL
MAVLLVLAAIFSRQISTPLRQISAAAHAIADGDHSSRVQTANVRELADLSASFNRMAEALQQADQQRRQLTADIAHELRT
PLSIIKGRLEGIQDGVYEADAEQIEALLTEVALLERLINDLHLLALADAGQLPLYREVVSPQMLVNEAIRSFTPAANERN
VRLSATIDDNLPDIEVDPQRIAQVLGNLIGNALRHTPAGGEVIVSAHRDESGIRFEVRDTGAGIDPADLPYIFDRFYKAD
RARSRSSGGAGLGLAIARRLVEAHGGQIWATSALQQGTTVSFRLPVSPTAPEPANQLSTGALLNNI

Sequences:

>Translated_466_residues
MRPPRLFNLMLTAFALVIVLGISGMALAFWLVVGQSNPEQMRWMEAEAAARTQAAQLAAYYQRVGSWRGVERQLGPLPQG
FGSIEGAVSLLDENGRVVAGRRRPMILRGNEAVLRIPIVVNNQQVGTLVISVIDTDEAFPVGNLNRRPLLLGMLSAGAGL
MAVLLVLAAIFSRQISTPLRQISAAAHAIADGDHSSRVQTANVRELADLSASFNRMAEALQQADQQRRQLTADIAHELRT
PLSIIKGRLEGIQDGVYEADAEQIEALLTEVALLERLINDLHLLALADAGQLPLYREVVSPQMLVNEAIRSFTPAANERN
VRLSATIDDNLPDIEVDPQRIAQVLGNLIGNALRHTPAGGEVIVSAHRDESGIRFEVRDTGAGIDPADLPYIFDRFYKAD
RARSRSSGGAGLGLAIARRLVEAHGGQIWATSALQQGTTVSFRLPVSPTAPEPANQLSTGALLNNI
>Mature_466_residues
MRPPRLFNLMLTAFALVIVLGISGMALAFWLVVGQSNPEQMRWMEAEAAARTQAAQLAAYYQRVGSWRGVERQLGPLPQG
FGSIEGAVSLLDENGRVVAGRRRPMILRGNEAVLRIPIVVNNQQVGTLVISVIDTDEAFPVGNLNRRPLLLGMLSAGAGL
MAVLLVLAAIFSRQISTPLRQISAAAHAIADGDHSSRVQTANVRELADLSASFNRMAEALQQADQQRRQLTADIAHELRT
PLSIIKGRLEGIQDGVYEADAEQIEALLTEVALLERLINDLHLLALADAGQLPLYREVVSPQMLVNEAIRSFTPAANERN
VRLSATIDDNLPDIEVDPQRIAQVLGNLIGNALRHTPAGGEVIVSAHRDESGIRFEVRDTGAGIDPADLPYIFDRFYKAD
RARSRSSGGAGLGLAIARRLVEAHGGQIWATSALQQGTTVSFRLPVSPTAPEPANQLSTGALLNNI

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=468, Percent_Identity=30.1282051282051, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1786783, Length=366, Percent_Identity=28.9617486338798, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI87081816, Length=346, Percent_Identity=31.5028901734104, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=31.140350877193, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=29.296875, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=33.4801762114537, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787894, Length=295, Percent_Identity=31.1864406779661, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790346, Length=270, Percent_Identity=30, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789149, Length=528, Percent_Identity=23.6742424242424, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786912, Length=259, Percent_Identity=32.046332046332, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789808, Length=285, Percent_Identity=28.4210526315789, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790861, Length=340, Percent_Identity=26.4705882352941, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788713, Length=230, Percent_Identity=29.1304347826087, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI48994928, Length=245, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=28.6290322580645, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788279, Length=275, Percent_Identity=26.5454545454545, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787374, Length=385, Percent_Identity=24.9350649350649, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790300, Length=255, Percent_Identity=31.7647058823529, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790551, Length=291, Percent_Identity=26.4604810996564, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87082128, Length=299, Percent_Identity=24.4147157190635, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789403, Length=285, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50322; Mature: 50322

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPPRLFNLMLTAFALVIVLGISGMALAFWLVVGQSNPEQMRWMEAEAAARTQAAQLAAY
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
YQRVGSWRGVERQLGPLPQGFGSIEGAVSLLDENGRVVAGRRRPMILRGNEAVLRIPIVV
HHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCEEECCCCCEEEECCCEEEEEEEEE
NNQQVGTLVISVIDTDEAFPVGNLNRRPLLLGMLSAGAGLMAVLLVLAAIFSRQISTPLR
CCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QISAAAHAIADGDHSSRVQTANVRELADLSASFNRMAEALQQADQQRRQLTADIAHELRT
HHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLSIIKGRLEGIQDGVYEADAEQIEALLTEVALLERLINDLHLLALADAGQLPLYREVVS
HHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHC
PQMLVNEAIRSFTPAANERNVRLSATIDDNLPDIEVDPQRIAQVLGNLIGNALRHTPAGG
HHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
EVIVSAHRDESGIRFEVRDTGAGIDPADLPYIFDRFYKADRARSRSSGGAGLGLAIARRL
CEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
VEAHGGQIWATSALQQGTTVSFRLPVSPTAPEPANQLSTGALLNNI
HHHCCCCEEEHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRPPRLFNLMLTAFALVIVLGISGMALAFWLVVGQSNPEQMRWMEAEAAARTQAAQLAAY
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
YQRVGSWRGVERQLGPLPQGFGSIEGAVSLLDENGRVVAGRRRPMILRGNEAVLRIPIVV
HHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCEEECCCCCEEEECCCEEEEEEEEE
NNQQVGTLVISVIDTDEAFPVGNLNRRPLLLGMLSAGAGLMAVLLVLAAIFSRQISTPLR
CCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QISAAAHAIADGDHSSRVQTANVRELADLSASFNRMAEALQQADQQRRQLTADIAHELRT
HHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLSIIKGRLEGIQDGVYEADAEQIEALLTEVALLERLINDLHLLALADAGQLPLYREVVS
HHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHC
PQMLVNEAIRSFTPAANERNVRLSATIDDNLPDIEVDPQRIAQVLGNLIGNALRHTPAGG
HHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
EVIVSAHRDESGIRFEVRDTGAGIDPADLPYIFDRFYKADRARSRSSGGAGLGLAIARRL
CEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
VEAHGGQIWATSALQQGTTVSFRLPVSPTAPEPANQLSTGALLNNI
HHHCCCCEEEHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]