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The map label for this gene is rsbRA [H]

Identifier: 222524209

GI number: 222524209

Start: 1173631

End: 1175592

Strand: Reverse

Name: rsbRA [H]

Synonym: Chy400_0930

Alternate gene names: 222524209

Gene position: 1175592-1173631 (Counterclockwise)

Preceding gene: 222524210

Following gene: 222524208

Centisome position: 22.31

GC content: 52.6

Gene sequence:

>1962_bases
ATGACACATCAATCGAGTTCATCGCCGTCCCTTCCCCCTCACCAACTCGAACACTTCTCCAGGGTTCTTGAATTTGCCGG
TCTGATCCTTACCGAGTCAGATGCGCAGGGGAATATCACCTATATCAACCAGGCTACCCGCCGCTACTTCGGCTACGCAC
CAGAGGAATGTATTGGGAAGTCGGTACTGGCCTTTACCCACCCCGATGATCGTGAAACCCTTCAGCAGACGATGATCGAA
CTCGTCAACCGCCAGCAACGCTCAGCAGAGATCGAAAATCGGGTGATTCATCGTGATGGTACCGTTTGTACATTCCTCTG
GTCAATCGTCATCCACTACGACGACAATGGTAACCTGACCGGGTTCACATCCATTGGCCAGGATATTTCGACACTTCATC
AATTGCGCGACAAATTGTACGAAAAACGCGAAATTCTCTACAACGTGATCGATAATCTTCCCCTGGGTATTTTCTGGAAA
GACAAAGAGTCGCGCTTTCTGGGTTGTAATCGACGTGTCCTTCAGGATGCCGGTCTCAGTACCTTCGCTGAAATTATTGG
CAAAACCGACTTTGAGTTGCCGTGGCGAGATAAGGCAGCCGCCTATCAGGCCCATGATCAGGTTGTGCTAACCTCTGGGC
CGCGGCTGAATATCGAAGAGACCCTTGTGCGTGGTGATGGCAGTTCCATCTGGTTGCGAACCGGCAAAGTACCACTGATC
CGCAATCAACAGGTGGCCGGTGTCATTGGCTTCTACGAAGATATTACCGAACAGCAACAGAAAGAACAAGAACGGCGAAC
ATTGCTCTTGCTCGTAGAGAATGCCCCCGATGGCATTGCGCTGCTCGATCCGCAGTTGACAATCACCTACGCCAACCCGG
CATGGTTGACGATGTTAGGCAAACACGAACTGGTTGGACAGTCGTGGGTCGATCTTGTGCATCCTGACGACCGTCCGCAG
ATTGCAACCATCGTTCAGCAGGCGAAGATCGGCAGCAGTCCGCGCACCAGGTTACGGTATATACACAGCGATGGTTCGGT
GATTACCGCATATATATCATTGCCGGTATTACGTAATCGCCAGGGTACGATCACCGGTTATGGCCTTATCAACCACGATA
TTACTGAAGAATTAAAGTCAGCGGAGCGGCTCAGGGCCAGTGAACAGCGCCAGCGCGCCCTCTTGCAGGCCATTCCTGAT
CTCATCTTTCTCATGACGCCAGATGGCGTTTTTCTTGATTATCACACAAATGAAATTGCCTTTGCTGTTCCACCAGAGCA
ATTTCTCAACCGACATTTTGCTGAGGTGTTGCCTCCAGCACTGGCCGAGCTGACGGCACGTAACCTGGAAGAATTGAAGC
GCACTGGCAGCATCCAGCGTTACGAGTACCAGATGCAGATAGATGGGCAGATACGCGACTATGAAGGACGTATGACGCTG
AGTGGGAATGATGTGTTGGTCGCGATTCGTGACATTACAGATCGGCGCCAGTCTGAGCGTGAACGCCAGACCATTGCGAT
GCAAGAGCAGATCATTGCCGCACAGCAAGCAATCTTACACGAACTGAGCACGCCATTGTTGCCAATTGCCGATGGAATTG
TGGCGATGCCGCTGATTGGGGCCATCGACTCAAGTCGTGCCCAGCTCGTGATGGAGTCCCTGCTCAGTGGCGTGGCTGAA
TATCGGGCGGCGATAGCGATTATCGACATCACTGGCGTCAAGGTGGTAGACACCCAGGTGGCGGGAGCGTTGCTGCGTAC
TGCCCAGGCGGCAGGGATGTTGGGCGCCCAGGTCGTGATTACCGGGATTCGACCGGAAATTGCGCAAACGATGGTGTATA
TCGGTGCTGATCTGGGTAATGTGGTGACGAAGGCAACACTGCAAGAGGGGATTGCCTTCGCGCTTAATCACCGGCGGGTC
AAACAATCAACGCAGAATGGAAACGTCAGGATGATGAAATAG

Upstream 100 bases:

>100_bases
CAGGTTCTGCATGACGTGCTGAAAAGCACCGATGCACAACCAAACTATCCTGCTTTACTATACCGCTTCGTAACAACCAG
GCAATGCAGGAGTTATCGAA

Downstream 100 bases:

>100_bases
CCGGCGTGCGTGGCGTGCATTGCGAAGATCAGGTCAGTACTCTACGAGTAGAGGGTCTGGTGATGCGTTGAACGTCCTCT
CCCCCGGACCCTCTCCCGCG

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 653; Mature: 652

Protein sequence:

>653_residues
MTHQSSSSPSLPPHQLEHFSRVLEFAGLILTESDAQGNITYINQATRRYFGYAPEECIGKSVLAFTHPDDRETLQQTMIE
LVNRQQRSAEIENRVIHRDGTVCTFLWSIVIHYDDNGNLTGFTSIGQDISTLHQLRDKLYEKREILYNVIDNLPLGIFWK
DKESRFLGCNRRVLQDAGLSTFAEIIGKTDFELPWRDKAAAYQAHDQVVLTSGPRLNIEETLVRGDGSSIWLRTGKVPLI
RNQQVAGVIGFYEDITEQQQKEQERRTLLLLVENAPDGIALLDPQLTITYANPAWLTMLGKHELVGQSWVDLVHPDDRPQ
IATIVQQAKIGSSPRTRLRYIHSDGSVITAYISLPVLRNRQGTITGYGLINHDITEELKSAERLRASEQRQRALLQAIPD
LIFLMTPDGVFLDYHTNEIAFAVPPEQFLNRHFAEVLPPALAELTARNLEELKRTGSIQRYEYQMQIDGQIRDYEGRMTL
SGNDVLVAIRDITDRRQSERERQTIAMQEQIIAAQQAILHELSTPLLPIADGIVAMPLIGAIDSSRAQLVMESLLSGVAE
YRAAIAIIDITGVKVVDTQVAGALLRTAQAAGMLGAQVVITGIRPEIAQTMVYIGADLGNVVTKATLQEGIAFALNHRRV
KQSTQNGNVRMMK

Sequences:

>Translated_653_residues
MTHQSSSSPSLPPHQLEHFSRVLEFAGLILTESDAQGNITYINQATRRYFGYAPEECIGKSVLAFTHPDDRETLQQTMIE
LVNRQQRSAEIENRVIHRDGTVCTFLWSIVIHYDDNGNLTGFTSIGQDISTLHQLRDKLYEKREILYNVIDNLPLGIFWK
DKESRFLGCNRRVLQDAGLSTFAEIIGKTDFELPWRDKAAAYQAHDQVVLTSGPRLNIEETLVRGDGSSIWLRTGKVPLI
RNQQVAGVIGFYEDITEQQQKEQERRTLLLLVENAPDGIALLDPQLTITYANPAWLTMLGKHELVGQSWVDLVHPDDRPQ
IATIVQQAKIGSSPRTRLRYIHSDGSVITAYISLPVLRNRQGTITGYGLINHDITEELKSAERLRASEQRQRALLQAIPD
LIFLMTPDGVFLDYHTNEIAFAVPPEQFLNRHFAEVLPPALAELTARNLEELKRTGSIQRYEYQMQIDGQIRDYEGRMTL
SGNDVLVAIRDITDRRQSERERQTIAMQEQIIAAQQAILHELSTPLLPIADGIVAMPLIGAIDSSRAQLVMESLLSGVAE
YRAAIAIIDITGVKVVDTQVAGALLRTAQAAGMLGAQVVITGIRPEIAQTMVYIGADLGNVVTKATLQEGIAFALNHRRV
KQSTQNGNVRMMK
>Mature_652_residues
THQSSSSPSLPPHQLEHFSRVLEFAGLILTESDAQGNITYINQATRRYFGYAPEECIGKSVLAFTHPDDRETLQQTMIEL
VNRQQRSAEIENRVIHRDGTVCTFLWSIVIHYDDNGNLTGFTSIGQDISTLHQLRDKLYEKREILYNVIDNLPLGIFWKD
KESRFLGCNRRVLQDAGLSTFAEIIGKTDFELPWRDKAAAYQAHDQVVLTSGPRLNIEETLVRGDGSSIWLRTGKVPLIR
NQQVAGVIGFYEDITEQQQKEQERRTLLLLVENAPDGIALLDPQLTITYANPAWLTMLGKHELVGQSWVDLVHPDDRPQI
ATIVQQAKIGSSPRTRLRYIHSDGSVITAYISLPVLRNRQGTITGYGLINHDITEELKSAERLRASEQRQRALLQAIPDL
IFLMTPDGVFLDYHTNEIAFAVPPEQFLNRHFAEVLPPALAELTARNLEELKRTGSIQRYEYQMQIDGQIRDYEGRMTLS
GNDVLVAIRDITDRRQSERERQTIAMQEQIIAAQQAILHELSTPLLPIADGIVAMPLIGAIDSSRAQLVMESLLSGVAEY
RAAIAIIDITGVKVVDTQVAGALLRTAQAAGMLGAQVVITGIRPEIAQTMVYIGADLGNVVTKATLQEGIAFALNHRRVK
QSTQNGNVRMMK

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 73123; Mature: 72991

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHQSSSSPSLPPHQLEHFSRVLEFAGLILTESDAQGNITYINQATRRYFGYAPEECIGK
CCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCEEEEEHHHHHHCCCCCHHHCCC
SVLAFTHPDDRETLQQTMIELVNRQQRSAEIENRVIHRDGTVCTFLWSIVIHYDDNGNLT
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHEEEEEEEEECCCCCEE
GFTSIGQDISTLHQLRDKLYEKREILYNVIDNLPLGIFWKDKESRFLGCNRRVLQDAGLS
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCHHHHHHCCHH
TFAEIIGKTDFELPWRDKAAAYQAHDQVVLTSGPRLNIEETLVRGDGSSIWLRTGKVPLI
HHHHHHCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCHHHHEEECCCCEEEEEECCCCEE
RNQQVAGVIGFYEDITEQQQKEQERRTLLLLVENAPDGIALLDPQLTITYANPAWLTMLG
CCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEEECCEEEEEECCCHHEEEEC
KHELVGQSWVDLVHPDDRPQIATIVQQAKIGSSPRTRLRYIHSDGSVITAYISLPVLRNR
CHHHCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECHHEECC
QGTITGYGLINHDITEELKSAERLRASEQRQRALLQAIPDLIFLMTPDGVFLDYHTNEIA
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCEEE
FAVPPEQFLNRHFAEVLPPALAELTARNLEELKRTGSIQRYEYQMQIDGQIRDYEGRMTL
EECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCEEEECCCEEEE
SGNDVLVAIRDITDRRQSERERQTIAMQEQIIAAQQAILHELSTPLLPIADGIVAMPLIG
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHH
AIDSSRAQLVMESLLSGVAEYRAAIAIIDITGVKVVDTQVAGALLRTAQAAGMLGAQVVI
CCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEHHHHHHHHHHHHHHHCCCCCEEEE
TGIRPEIAQTMVYIGADLGNVVTKATLQEGIAFALNHRRVKQSTQNGNVRMMK
ECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
>Mature Secondary Structure 
THQSSSSPSLPPHQLEHFSRVLEFAGLILTESDAQGNITYINQATRRYFGYAPEECIGK
CCCCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCEEEEEHHHHHHCCCCCHHHCCC
SVLAFTHPDDRETLQQTMIELVNRQQRSAEIENRVIHRDGTVCTFLWSIVIHYDDNGNLT
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHEEEEEEEEECCCCCEE
GFTSIGQDISTLHQLRDKLYEKREILYNVIDNLPLGIFWKDKESRFLGCNRRVLQDAGLS
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCHHHHHHCCHH
TFAEIIGKTDFELPWRDKAAAYQAHDQVVLTSGPRLNIEETLVRGDGSSIWLRTGKVPLI
HHHHHHCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCHHHHEEECCCCEEEEEECCCCEE
RNQQVAGVIGFYEDITEQQQKEQERRTLLLLVENAPDGIALLDPQLTITYANPAWLTMLG
CCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEEECCEEEEEECCCHHEEEEC
KHELVGQSWVDLVHPDDRPQIATIVQQAKIGSSPRTRLRYIHSDGSVITAYISLPVLRNR
CHHHCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECHHEECC
QGTITGYGLINHDITEELKSAERLRASEQRQRALLQAIPDLIFLMTPDGVFLDYHTNEIA
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCEEE
FAVPPEQFLNRHFAEVLPPALAELTARNLEELKRTGSIQRYEYQMQIDGQIRDYEGRMTL
EECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCEEEECCCEEEE
SGNDVLVAIRDITDRRQSERERQTIAMQEQIIAAQQAILHELSTPLLPIADGIVAMPLIG
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHH
AIDSSRAQLVMESLLSGVAEYRAAIAIIDITGVKVVDTQVAGALLRTAQAAGMLGAQVVI
CCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEHHHHHHHHHHHHHHHCCCCCEEEE
TGIRPEIAQTMVYIGADLGNVVTKATLQEGIAFALNHRRVKQSTQNGNVRMMK
ECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]