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The map label for this gene is rsbRA [H]

Identifier: 222524193

GI number: 222524193

Start: 1153699

End: 1154733

Strand: Reverse

Name: rsbRA [H]

Synonym: Chy400_0914

Alternate gene names: 222524193

Gene position: 1154733-1153699 (Counterclockwise)

Preceding gene: 222524195

Following gene: 222524190

Centisome position: 21.92

GC content: 57.78

Gene sequence:

>1035_bases
ATGGGCACCTCGCAAACATTTCTCGAACAAACACACCGGCGCATTACCTGGTCAATTGCACTCGGTACGTTGATCATCTC
GGTCGCTGCGTTCGTGATCACTCTGCTGGCCTCGCTCTTCAGCCAGAGTGTGTTTACGGTTATCATTCTGACGATTACGC
TGATTACCGGGATTGGCTGTGCGATCACATTGCTGGTGTTAGCCCGCCAGCAACCGCTCTGGCAGGCAATCGTCACCTTT
GGTCTCATGATCATTGCCTGTGAAGTGGCAATTGCAATCTGGCTACCCGAATTGCGACTTGCCACTATCCCCTTTCTGGC
CGTAGTCATTTTGCTGGCCGGGCTGCAAGGGCAGCGCAGCTTCTCAATCGGCGCGACGGTTCTGTGTGTGGTGGTGGCGA
TTCCGTTAGTTGTTCTGAACCAGTCCACCACCGACACCCGCATTGCGCCGCATCTGCTGATGTTTCTGGAAACCAGCAGT
ATTGTGGCGCTGTTTGTCGCGATTTGGGCTTTCCTCGACCGCACGATGACCGCTCAGATGCAGGCGTTGCGGCTCGCCGA
TCAGCGGGCCGATGAGGCCGAAGCGGCTCGCCAGGCCACAGAGGTGGCGCGGCAAGAGATCGAGCAGCGGGCGCTTGAGC
AGCAGCGGTTGCTTGAGTTGATCGATGTGCTGGAGTTGCCGGTGTTAACGATTGACGATAAGGTGCTGCTGGCGCCACTG
GTCGGTCATCTCGATAGTCGGCGCACCGAAGCGTTGCGCGGGCGGTTGCTGGATATGGTTGCCAGCCGTCGGGCACATAC
GGTGATTATTGATGTGACCGGTATTTCGTTTATTGATACCGCTGTTGCGAAGGCGCTGATCGATACCGCAACGGCGATTC
GGCTGCTCGGTGCACGCACGATTGTCAGTGGAATCGGCCCGTCGGTGGCGCAGACCCTGGTGCATCTGAATGTCGGTCTG
GCCGAGATCGCTACTGCACCAAATCCTGAAGCGGCATTGCGTCTGACGCACGCTGTTGCGGTGAATGGGGCGTAG

Upstream 100 bases:

>100_bases
ATTGTTAATTGCAAGCAAGGGATGGATTGTACACCTTACAATTTTGTCATTATCACGTGCGCAGGACTAAACACTTATTC
ATCTTGATGGGAGTCCGACC

Downstream 100 bases:

>100_bases
GGATGGCATCCAGGAGGGAGCGGGGAGTAGGGAATGGGCGTGCGCCAGATGGCTCCCGTTCACTTTGATCGCCCCCTCAC
CTCACCCCCCAGCCCCTGCT

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGTSQTFLEQTHRRITWSIALGTLIISVAAFVITLLASLFSQSVFTVIILTITLITGIGCAITLLVLARQQPLWQAIVTF
GLMIIACEVAIAIWLPELRLATIPFLAVVILLAGLQGQRSFSIGATVLCVVVAIPLVVLNQSTTDTRIAPHLLMFLETSS
IVALFVAIWAFLDRTMTAQMQALRLADQRADEAEAARQATEVARQEIEQRALEQQRLLELIDVLELPVLTIDDKVLLAPL
VGHLDSRRTEALRGRLLDMVASRRAHTVIIDVTGISFIDTAVAKALIDTATAIRLLGARTIVSGIGPSVAQTLVHLNVGL
AEIATAPNPEAALRLTHAVAVNGA

Sequences:

>Translated_344_residues
MGTSQTFLEQTHRRITWSIALGTLIISVAAFVITLLASLFSQSVFTVIILTITLITGIGCAITLLVLARQQPLWQAIVTF
GLMIIACEVAIAIWLPELRLATIPFLAVVILLAGLQGQRSFSIGATVLCVVVAIPLVVLNQSTTDTRIAPHLLMFLETSS
IVALFVAIWAFLDRTMTAQMQALRLADQRADEAEAARQATEVARQEIEQRALEQQRLLELIDVLELPVLTIDDKVLLAPL
VGHLDSRRTEALRGRLLDMVASRRAHTVIIDVTGISFIDTAVAKALIDTATAIRLLGARTIVSGIGPSVAQTLVHLNVGL
AEIATAPNPEAALRLTHAVAVNGA
>Mature_343_residues
GTSQTFLEQTHRRITWSIALGTLIISVAAFVITLLASLFSQSVFTVIILTITLITGIGCAITLLVLARQQPLWQAIVTFG
LMIIACEVAIAIWLPELRLATIPFLAVVILLAGLQGQRSFSIGATVLCVVVAIPLVVLNQSTTDTRIAPHLLMFLETSSI
VALFVAIWAFLDRTMTAQMQALRLADQRADEAEAARQATEVARQEIEQRALEQQRLLELIDVLELPVLTIDDKVLLAPLV
GHLDSRRTEALRGRLLDMVASRRAHTVIIDVTGISFIDTAVAKALIDTATAIRLLGARTIVSGIGPSVAQTLVHLNVGLA
EIATAPNPEAALRLTHAVAVNGA

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 37016; Mature: 36885

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTSQTFLEQTHRRITWSIALGTLIISVAAFVITLLASLFSQSVFTVIILTITLITGIGC
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AITLLVLARQQPLWQAIVTFGLMIIACEVAIAIWLPELRLATIPFLAVVILLAGLQGQRS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
FSIGATVLCVVVAIPLVVLNQSTTDTRIAPHLLMFLETSSIVALFVAIWAFLDRTMTAQM
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALRLADQRADEAEAARQATEVARQEIEQRALEQQRLLELIDVLELPVLTIDDKVLLAPL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHH
VGHLDSRRTEALRGRLLDMVASRRAHTVIIDVTGISFIDTAVAKALIDTATAIRLLGART
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
IVSGIGPSVAQTLVHLNVGLAEIATAPNPEAALRLTHAVAVNGA
HHHHCCHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHEECCC
>Mature Secondary Structure 
GTSQTFLEQTHRRITWSIALGTLIISVAAFVITLLASLFSQSVFTVIILTITLITGIGC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AITLLVLARQQPLWQAIVTFGLMIIACEVAIAIWLPELRLATIPFLAVVILLAGLQGQRS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
FSIGATVLCVVVAIPLVVLNQSTTDTRIAPHLLMFLETSSIVALFVAIWAFLDRTMTAQM
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALRLADQRADEAEAARQATEVARQEIEQRALEQQRLLELIDVLELPVLTIDDKVLLAPL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHH
VGHLDSRRTEALRGRLLDMVASRRAHTVIIDVTGISFIDTAVAKALIDTATAIRLLGART
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
IVSGIGPSVAQTLVHLNVGLAEIATAPNPEAALRLTHAVAVNGA
HHHHCCHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]