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The map label for this gene is gapN [H]

Identifier: 222523919

GI number: 222523919

Start: 770232

End: 771776

Strand: Reverse

Name: gapN [H]

Synonym: Chy400_0630

Alternate gene names: 222523919

Gene position: 771776-770232 (Counterclockwise)

Preceding gene: 222523922

Following gene: 222523918

Centisome position: 14.65

GC content: 54.17

Gene sequence:

>1545_bases
ATGAGCAAAATCATCGCACCAGAGTGTGAATGGTCGCATCTCCTGGCACAATTACGATCTGTTGTACCAGAGGCCTTTAA
CAGTGAAGGGCACGTTCTCAATTTGATCGAGGGAACGTGGGGATGGCCGGGGCATGGTAAGCATTACAGTACGCCCATTG
ATGGCACGGAATTGGGCCGCATGCCCATGATTGACCTCGAAACGGCAAAGCGGGCTGTGCGTTTTGCCGCTCGTGAACAT
GAGACCTGGGCACGAACTGATCTCGATGAGCGACGGCGACGGGTGCGGGAGACGGTTGATGGCTTACGACAGCACCGCGA
TCTGATCGCATATCTGCTGATGTGGGAGATTGGCAAGCCATACCATCTGGCGTGTGATGATGTTGATCGCTGTCTTGATG
GTGTCGAATGGTATATTGATCAGATCGAATGGATGCTGAGTAACCGCCAGCCGCTCGGTCTGATATCGAATATTGCCTCG
TGGAACTATCCGTACTCGGTGTTAGTCCACGCGGTATTGGTGCAGGCACTGGCCGGTAATGCCGTCATTGCCAAAACCCC
GTCAGATGGTGGCTTGTTCGCGTTAACGCTAGGTTTTGCGATTGCCCGTCGGGCTGGCCTGCCTGTCTCGCTGGTCAGTG
GATCGGGTGGTGCGCTCAGCGATGCTCTGGTACGGAATGCCGATGTAGCGTGTCTGGCGTTTGTAGGCGGGAAAACTAAC
GGACGTGATATTGCTGCGTCGCTCTACGACCGCAACAAACGCTACATGCTGGAGATGGAAGGGGTGAACTGCTACGGCAT
CTGGGATTTCTCTGATTGGGCGAGTCTGGCTCAGCAGATTAAAAAGGGCTTTGCTTACGGTAAACAGCGGTGTACGGCCT
ACATCCGTTATGTTGTTCAGCGCCGACTCTTTCCCAAGTTCCTGGATGTGTATTTGCCGGTTCTAAAGAGCTTGCAGATC
GGCAATCCGGTACTGGTTGATCGGGCTGGTGATCCGTTGCCACGGCTCGATTTTGGCCCCCTCATCAATGCGAGGAAGGT
TGAAGAGCTACGTGTGCTCTACAGCGAGGCGCTGGGTGCCGGTGCGGTTTGTCTGTACGAAGGCGAATTGAACCCAGAGC
TGTTTTTACCCGATCAGGACATTTCGGCCTATATGGCGCCGATTGCGTTGTTGAATGTGCCACGGAATTGCCGCCTGCAC
CACAACGAACCGTTTGGCCCGATTGATACGATTGTGATTGTTGATAGTATCGAGGAGCTGATCAGCGAGATGAATATCTC
GAATGGGAATCTGGTGTCCTCGATTGCGACCGATGATCTCAGGTTGGGCCAGATGATTGCAAGTGAGTTGCGTGCATTCA
AGGTCGGCATCAACCGTATGCGCTCGCGTGGTGATCGCGATGAGGTGTTTGGCGGGATGGGCGCATCCTGGAAGGGTTGT
TTTGTGGGTGGTAAGTATCTGGTTGAAGCAGTGACAGTCGGCGCGCCGGGAGAGCGGTTGTACGGTAATTTTCCCGATTA
CACGCTGCTGCCAGAGCAACGGTAA

Upstream 100 bases:

>100_bases
ATATTGTATGTCAACATATTTAGCAGTTTGTGAGAATGATAGTAACCGGCATGATATACTGTGATTGTGCTAAATATCAC
AGTACCGGAAGAGGGATGGC

Downstream 100 bases:

>100_bases
CGAGAGGACGGGCAGACGCAGGATATGCTGATAACACTTGCTGAACCGGCTACAGATCAACCGGTGGTGAAGCCGCTACA
ACCTGCTATCGAGATACACG

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: Glyceraldehyde-3-phosphate dehydrogenase [NADP+]; Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase; Triosephosphate dehydrogenase [H]

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MSKIIAPECEWSHLLAQLRSVVPEAFNSEGHVLNLIEGTWGWPGHGKHYSTPIDGTELGRMPMIDLETAKRAVRFAAREH
ETWARTDLDERRRRVRETVDGLRQHRDLIAYLLMWEIGKPYHLACDDVDRCLDGVEWYIDQIEWMLSNRQPLGLISNIAS
WNYPYSVLVHAVLVQALAGNAVIAKTPSDGGLFALTLGFAIARRAGLPVSLVSGSGGALSDALVRNADVACLAFVGGKTN
GRDIAASLYDRNKRYMLEMEGVNCYGIWDFSDWASLAQQIKKGFAYGKQRCTAYIRYVVQRRLFPKFLDVYLPVLKSLQI
GNPVLVDRAGDPLPRLDFGPLINARKVEELRVLYSEALGAGAVCLYEGELNPELFLPDQDISAYMAPIALLNVPRNCRLH
HNEPFGPIDTIVIVDSIEELISEMNISNGNLVSSIATDDLRLGQMIASELRAFKVGINRMRSRGDRDEVFGGMGASWKGC
FVGGKYLVEAVTVGAPGERLYGNFPDYTLLPEQR

Sequences:

>Translated_514_residues
MSKIIAPECEWSHLLAQLRSVVPEAFNSEGHVLNLIEGTWGWPGHGKHYSTPIDGTELGRMPMIDLETAKRAVRFAAREH
ETWARTDLDERRRRVRETVDGLRQHRDLIAYLLMWEIGKPYHLACDDVDRCLDGVEWYIDQIEWMLSNRQPLGLISNIAS
WNYPYSVLVHAVLVQALAGNAVIAKTPSDGGLFALTLGFAIARRAGLPVSLVSGSGGALSDALVRNADVACLAFVGGKTN
GRDIAASLYDRNKRYMLEMEGVNCYGIWDFSDWASLAQQIKKGFAYGKQRCTAYIRYVVQRRLFPKFLDVYLPVLKSLQI
GNPVLVDRAGDPLPRLDFGPLINARKVEELRVLYSEALGAGAVCLYEGELNPELFLPDQDISAYMAPIALLNVPRNCRLH
HNEPFGPIDTIVIVDSIEELISEMNISNGNLVSSIATDDLRLGQMIASELRAFKVGINRMRSRGDRDEVFGGMGASWKGC
FVGGKYLVEAVTVGAPGERLYGNFPDYTLLPEQR
>Mature_513_residues
SKIIAPECEWSHLLAQLRSVVPEAFNSEGHVLNLIEGTWGWPGHGKHYSTPIDGTELGRMPMIDLETAKRAVRFAAREHE
TWARTDLDERRRRVRETVDGLRQHRDLIAYLLMWEIGKPYHLACDDVDRCLDGVEWYIDQIEWMLSNRQPLGLISNIASW
NYPYSVLVHAVLVQALAGNAVIAKTPSDGGLFALTLGFAIARRAGLPVSLVSGSGGALSDALVRNADVACLAFVGGKTNG
RDIAASLYDRNKRYMLEMEGVNCYGIWDFSDWASLAQQIKKGFAYGKQRCTAYIRYVVQRRLFPKFLDVYLPVLKSLQIG
NPVLVDRAGDPLPRLDFGPLINARKVEELRVLYSEALGAGAVCLYEGELNPELFLPDQDISAYMAPIALLNVPRNCRLHH
NEPFGPIDTIVIVDSIEELISEMNISNGNLVSSIATDDLRLGQMIASELRAFKVGINRMRSRGDRDEVFGGMGASWKGCF
VGGKYLVEAVTVGAPGERLYGNFPDYTLLPEQR

Specific function: Acts On Lactaldehyde As Well As Other Aldehydes. [C]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI153266822, Length=485, Percent_Identity=24.5360824742268, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI12007648, Length=448, Percent_Identity=25.2232142857143, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI25777724, Length=457, Percent_Identity=24.72647702407, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI25777730, Length=459, Percent_Identity=26.1437908496732, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI25777732, Length=459, Percent_Identity=27.0152505446623, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI115387104, Length=404, Percent_Identity=26.2376237623762, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI25777728, Length=423, Percent_Identity=24.3498817966903, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI238814322, Length=487, Percent_Identity=24.8459958932238, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI21361176, Length=413, Percent_Identity=23.9709443099274, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4507229, Length=398, Percent_Identity=22.6130653266332, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI25777721, Length=410, Percent_Identity=22.4390243902439, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI188035924, Length=424, Percent_Identity=20.9905660377358, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI310128103, Length=424, Percent_Identity=20.9905660377358, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI21614513, Length=440, Percent_Identity=22.7272727272727, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI310128093, Length=424, Percent_Identity=20.7547169811321, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI11095441, Length=429, Percent_Identity=23.0769230769231, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI301500698, Length=272, Percent_Identity=25.3676470588235, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI310128091, Length=412, Percent_Identity=22.3300970873786, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787684, Length=456, Percent_Identity=26.0964912280702, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789015, Length=477, Percent_Identity=24.7379454926625, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1787558, Length=445, Percent_Identity=25.6179775280899, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1786504, Length=446, Percent_Identity=26.2331838565022, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87081926, Length=447, Percent_Identity=24.6085011185682, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI87081896, Length=462, Percent_Identity=24.8917748917749, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787715, Length=390, Percent_Identity=23.8461538461538, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87082295, Length=451, Percent_Identity=22.6164079822616, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1787250, Length=463, Percent_Identity=24.4060475161987, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25143874, Length=467, Percent_Identity=24.6252676659529, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI25143876, Length=467, Percent_Identity=24.6252676659529, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI25144435, Length=474, Percent_Identity=25.9493670886076, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17551164, Length=451, Percent_Identity=25.2771618625277, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17534119, Length=448, Percent_Identity=22.9910714285714, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562198, Length=459, Percent_Identity=24.400871459695, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32564736, Length=428, Percent_Identity=25.7009345794392, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI133930964, Length=489, Percent_Identity=24.7443762781186, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71995606, Length=455, Percent_Identity=25.2747252747253, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71995613, Length=411, Percent_Identity=24.8175182481752, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71986308, Length=431, Percent_Identity=23.4338747099768, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI115534176, Length=429, Percent_Identity=22.1445221445221, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325196, Length=435, Percent_Identity=26.2068965517241, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6323822, Length=445, Percent_Identity=23.8202247191011, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319478, Length=497, Percent_Identity=22.5352112676056, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323821, Length=443, Percent_Identity=22.5733634311512, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6324950, Length=434, Percent_Identity=23.963133640553, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320917, Length=428, Percent_Identity=23.1308411214953, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281362580, Length=448, Percent_Identity=22.9910714285714, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI62472918, Length=448, Percent_Identity=22.9910714285714, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI62472926, Length=448, Percent_Identity=22.9910714285714, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI62472936, Length=448, Percent_Identity=22.9910714285714, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21356737, Length=448, Percent_Identity=22.9910714285714, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI20129399, Length=413, Percent_Identity=24.2130750605327, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24666674, Length=465, Percent_Identity=22.7956989247312, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24650465, Length=411, Percent_Identity=22.3844282238443, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24585660, Length=351, Percent_Identity=25.3561253561254, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24638878, Length=418, Percent_Identity=22.488038277512, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24638876, Length=418, Percent_Identity=22.488038277512, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: 280 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.9 [H]

Molecular weight: Translated: 57214; Mature: 57083

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIIAPECEWSHLLAQLRSVVPEAFNSEGHVLNLIEGTWGWPGHGKHYSTPIDGTELGR
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
MPMIDLETAKRAVRFAAREHETWARTDLDERRRRVRETVDGLRQHRDLIAYLLMWEIGKP
CCEEEHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YHLACDDVDRCLDGVEWYIDQIEWMLSNRQPLGLISNIASWNYPYSVLVHAVLVQALAGN
CEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
AVIAKTPSDGGLFALTLGFAIARRAGLPVSLVSGSGGALSDALVRNADVACLAFVGGKTN
EEEEECCCCCCEEHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCCEEEEEEECCCCC
GRDIAASLYDRNKRYMLEMEGVNCYGIWDFSDWASLAQQIKKGFAYGKQRCTAYIRYVVQ
CHHHHHHHHHCCCEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLFPKFLDVYLPVLKSLQIGNPVLVDRAGDPLPRLDFGPLINARKVEELRVLYSEALGA
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
GAVCLYEGELNPELFLPDQDISAYMAPIALLNVPRNCRLHHNEPFGPIDTIVIVDSIEEL
CEEEEEECCCCCEEECCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCHHHEEEHHHHHHH
ISEMNISNGNLVSSIATDDLRLGQMIASELRAFKVGINRMRSRGDRDEVFGGMGASWKGC
HHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEE
FVGGKYLVEAVTVGAPGERLYGNFPDYTLLPEQR
EECHHHEEHHEECCCCCHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKIIAPECEWSHLLAQLRSVVPEAFNSEGHVLNLIEGTWGWPGHGKHYSTPIDGTELGR
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
MPMIDLETAKRAVRFAAREHETWARTDLDERRRRVRETVDGLRQHRDLIAYLLMWEIGKP
CCEEEHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YHLACDDVDRCLDGVEWYIDQIEWMLSNRQPLGLISNIASWNYPYSVLVHAVLVQALAGN
CEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
AVIAKTPSDGGLFALTLGFAIARRAGLPVSLVSGSGGALSDALVRNADVACLAFVGGKTN
EEEEECCCCCCEEHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCCEEEEEEECCCCC
GRDIAASLYDRNKRYMLEMEGVNCYGIWDFSDWASLAQQIKKGFAYGKQRCTAYIRYVVQ
CHHHHHHHHHCCCEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLFPKFLDVYLPVLKSLQIGNPVLVDRAGDPLPRLDFGPLINARKVEELRVLYSEALGA
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
GAVCLYEGELNPELFLPDQDISAYMAPIALLNVPRNCRLHHNEPFGPIDTIVIVDSIEEL
CEEEEEECCCCCEEECCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCHHHEEEHHHHHHH
ISEMNISNGNLVSSIATDDLRLGQMIASELRAFKVGINRMRSRGDRDEVFGGMGASWKGC
HHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEE
FVGGKYLVEAVTVGAPGERLYGNFPDYTLLPEQR
EECHHHEEHHEECCCCCHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7751269; 12397186 [H]