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The map label for this gene is degU [H]

Identifier: 222523841

GI number: 222523841

Start: 655793

End: 657043

Strand: Reverse

Name: degU [H]

Synonym: Chy400_0549

Alternate gene names: 222523841

Gene position: 657043-655793 (Counterclockwise)

Preceding gene: 222523842

Following gene: 222523840

Centisome position: 12.47

GC content: 52.84

Gene sequence:

>1251_bases
ATGAGCGAAGGCGATAAGATTCGAGTAATGATCGTTGATGACGTGATCGATACTCGCGATCAGCTCGAAAAGCTACTATT
CTTTGAGAAGGATATTGAAGTCGTTGCCAAAGCAAGCAACGGACGTGAAGCAATTGCGCTTGCTCGCCAGCATCGTCCAC
AGGTTATTTTGATGGACATTAATATGCCCGATATGGATGGGATCGCGGCTACAGAAGCGATTCTAACCAATGATCCGGGC
ATACAAGTCATTATCATGAGCGTGCAGGGCGAAACCGATTATATTCGGCGAGCAATGCTGGCGGGCGCCCGCGAGTTTCT
GATTAAGCCGATCAGCGCCGATGATCTTTACCGGTCGATCCGCCATGTGGCCCGTCTGGCAATGACCCGACCGATAGCTC
CGGTTGGTGCCCCTGGTGGACAAGTGCCTGGTGCTCAACCCACTGTTGACGGCCAGATCTTTGCCGTATTTAGTCCGAAA
GGTGGGGTTGGGGTCTCATCGATTGCGGCTAATCTGGCCGTAGCCATTCGCCAGCAAACTAATAAAAAGGTGGCGCTGGT
CGATGGGAATGTGATCTTTGGTGATCTCAGTGTCCTGCTGAATCTACGCACCGATAAGACAATTCTCGATGTTGCATCAC
GGATTGAAGGGCTTGATCGCGATCTGTTGAATGACGTGATGGCTACCCATCCCACGCAGGTGAAGGTATTGCTGGCCCCC
CCTGATCCGCAGCGTGGCGAATTAGTCTCCGCCGATCACATCCGTGCCATTCTCGAAGCTATCCGCCAGGAGTTCGATTA
CGTTATCGTCGATACACCGGCTTCGTTCCAGGATCGCTCGCTGGCTGCCCTCGACCTGGCGCAGCGGGTAATCACCCTCA
TGACGCTTGAGATGCACTGTATCCGTAATGTCAAGCTCTTCCTTGAGGTGGCTGATCTGCTCGGTTATCCCAACGATAAG
GTCATGCTGGTACTCAACAAAGCGACCAATCGTACCGGGATTCGGGCCGAAGATGTCGAGAAGCACCTTCAACGTAAGCT
GGCGTTGCAGATCGGTGATGCCGCTCAGGAGATGACGCTCTCGATTAATCAGGGAACGCCATTGGTGCTGGCAAAGCCAA
ACCATCAGGTAGCAAAAGACATCATGAACCTGGCCCGTGAATTGGTAGCCAAGGCGAGTAAAGAGGCAGCAGCGAAAGAG
AGTTCAAAGCAGCGCAGTGGCTTATTCGGTAATTTGATCCCCCGGCGATAA

Upstream 100 bases:

>100_bases
TGACATCGTAGCATTCTATCATATAGTCATAAACTGTCTTGATCGTTTGCCACAACTCACGTCCGTTTTTGAACGACGAG
GCCATCTGAGGAGCTAGAGC

Downstream 100 bases:

>100_bases
ACAATACCGGATTCTGCCTGATACGCTGCTTTACCACTGAGAAAGGTGAGCGCAATGTCGTTGTTGAAGCGAATTGGTGG
TGGTGTTCCTGCAACAACCG

Product: response regulator receiver protein

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MSEGDKIRVMIVDDVIDTRDQLEKLLFFEKDIEVVAKASNGREAIALARQHRPQVILMDINMPDMDGIAATEAILTNDPG
IQVIIMSVQGETDYIRRAMLAGAREFLIKPISADDLYRSIRHVARLAMTRPIAPVGAPGGQVPGAQPTVDGQIFAVFSPK
GGVGVSSIAANLAVAIRQQTNKKVALVDGNVIFGDLSVLLNLRTDKTILDVASRIEGLDRDLLNDVMATHPTQVKVLLAP
PDPQRGELVSADHIRAILEAIRQEFDYVIVDTPASFQDRSLAALDLAQRVITLMTLEMHCIRNVKLFLEVADLLGYPNDK
VMLVLNKATNRTGIRAEDVEKHLQRKLALQIGDAAQEMTLSINQGTPLVLAKPNHQVAKDIMNLARELVAKASKEAAAKE
SSKQRSGLFGNLIPRR

Sequences:

>Translated_416_residues
MSEGDKIRVMIVDDVIDTRDQLEKLLFFEKDIEVVAKASNGREAIALARQHRPQVILMDINMPDMDGIAATEAILTNDPG
IQVIIMSVQGETDYIRRAMLAGAREFLIKPISADDLYRSIRHVARLAMTRPIAPVGAPGGQVPGAQPTVDGQIFAVFSPK
GGVGVSSIAANLAVAIRQQTNKKVALVDGNVIFGDLSVLLNLRTDKTILDVASRIEGLDRDLLNDVMATHPTQVKVLLAP
PDPQRGELVSADHIRAILEAIRQEFDYVIVDTPASFQDRSLAALDLAQRVITLMTLEMHCIRNVKLFLEVADLLGYPNDK
VMLVLNKATNRTGIRAEDVEKHLQRKLALQIGDAAQEMTLSINQGTPLVLAKPNHQVAKDIMNLARELVAKASKEAAAKE
SSKQRSGLFGNLIPRR
>Mature_415_residues
SEGDKIRVMIVDDVIDTRDQLEKLLFFEKDIEVVAKASNGREAIALARQHRPQVILMDINMPDMDGIAATEAILTNDPGI
QVIIMSVQGETDYIRRAMLAGAREFLIKPISADDLYRSIRHVARLAMTRPIAPVGAPGGQVPGAQPTVDGQIFAVFSPKG
GVGVSSIAANLAVAIRQQTNKKVALVDGNVIFGDLSVLLNLRTDKTILDVASRIEGLDRDLLNDVMATHPTQVKVLLAPP
DPQRGELVSADHIRAILEAIRQEFDYVIVDTPASFQDRSLAALDLAQRVITLMTLEMHCIRNVKLFLEVADLLGYPNDKV
MLVLNKATNRTGIRAEDVEKHLQRKLALQIGDAAQEMTLSINQGTPLVLAKPNHQVAKDIMNLARELVAKASKEAAAKES
SKQRSGLFGNLIPRR

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=119, Percent_Identity=36.9747899159664, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=36.6071428571429, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788222, Length=117, Percent_Identity=32.4786324786325, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790437, Length=128, Percent_Identity=33.59375, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 45497; Mature: 45365

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGDKIRVMIVDDVIDTRDQLEKLLFFEKDIEVVAKASNGREAIALARQHRPQVILMDI
CCCCCEEEEEEECCHHCCHHHHHHHHHHHHCHHHEEECCCCHHHHHHHHHCCCEEEEEEC
NMPDMDGIAATEAILTNDPGIQVIIMSVQGETDYIRRAMLAGAREFLIKPISADDLYRSI
CCCCCCCHHHHHHEEECCCCEEEEEEEECCCHHHHHHHHHHCCHHHHCCCCCHHHHHHHH
RHVARLAMTRPIAPVGAPGGQVPGAQPTVDGQIFAVFSPKGGVGVSSIAANLAVAIRQQT
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCC
NKKVALVDGNVIFGDLSVLLNLRTDKTILDVASRIEGLDRDLLNDVMATHPTQVKVLLAP
CCEEEEEECCEEEEEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECC
PDPQRGELVSADHIRAILEAIRQEFDYVIVDTPASFQDRSLAALDLAQRVITLMTLEMHC
CCCCCCCEECHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IRNVKLFLEVADLLGYPNDKVMLVLNKATNRTGIRAEDVEKHLQRKLALQIGDAAQEMTL
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEE
SINQGTPLVLAKPNHQVAKDIMNLARELVAKASKEAAAKESSKQRSGLFGNLIPRR
EECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SEGDKIRVMIVDDVIDTRDQLEKLLFFEKDIEVVAKASNGREAIALARQHRPQVILMDI
CCCCEEEEEEECCHHCCHHHHHHHHHHHHCHHHEEECCCCHHHHHHHHHCCCEEEEEEC
NMPDMDGIAATEAILTNDPGIQVIIMSVQGETDYIRRAMLAGAREFLIKPISADDLYRSI
CCCCCCCHHHHHHEEECCCCEEEEEEEECCCHHHHHHHHHHCCHHHHCCCCCHHHHHHHH
RHVARLAMTRPIAPVGAPGGQVPGAQPTVDGQIFAVFSPKGGVGVSSIAANLAVAIRQQT
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCC
NKKVALVDGNVIFGDLSVLLNLRTDKTILDVASRIEGLDRDLLNDVMATHPTQVKVLLAP
CCEEEEEECCEEEEEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECC
PDPQRGELVSADHIRAILEAIRQEFDYVIVDTPASFQDRSLAALDLAQRVITLMTLEMHC
CCCCCCCEECHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IRNVKLFLEVADLLGYPNDKVMLVLNKATNRTGIRAEDVEKHLQRKLALQIGDAAQEMTL
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEE
SINQGTPLVLAKPNHQVAKDIMNLARELVAKASKEAAAKESSKQRSGLFGNLIPRR
EECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]