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The map label for this gene is cisA [H]

Identifier: 222523608

GI number: 222523608

Start: 375889

End: 377412

Strand: Direct

Name: cisA [H]

Synonym: Chy400_0314

Alternate gene names: 222523608

Gene position: 375889-377412 (Clockwise)

Preceding gene: 222523594

Following gene: 222523611

Centisome position: 7.13

GC content: 56.63

Gene sequence:

>1524_bases
ATGCACGCGGTCATCTATGCGCGGGTAAGCACGGAAGAGCAGGGGGATAACTTTAGCATTCCGGCCCAGCTTGCGGCCTG
CCGGGAATATGCCGAGCGCAACGGGTTGCAGGTAGTAGCCGAGTGCATCGATACGATGAGCGGTGCGCGGTTAGATCGGC
CCGGCTTGCAGCAAGTGCGTGATCTGGTATCGCAACAGTTGGTGCAAGCGGTGATTGTGTATCACCAAGATCGCTTATCA
CGTAATCTTGCGCACTTTTTGTACCTGCGCGATGAGTTTCAGAACGCGCGTATTGCGTTGCACTTTACCACGCTTGGACA
GGCGCGCGATACGCCAGAAGATAAACTCATTCAAAACATGATCGGTTCCTTTGCCGAGCATGAGCGGTTGCGCATTATTG
AACGCACGAAGCAAGGCCGGCGCGCTCGATTGCTATCCGGCAAGCCGCTTGGCCTCGGTAATCACCCTGCCTATGGGTAT
CACTGGCATGGAACCAAGCATGATCGTCACTTACACATCAACGAAGCGGAAGCGGCAATTGTCCGCCGCATCTTTGCTTG
GGCATTGGAAGGCGTGCCTACCCAACGCATTGCGAAGCTGCTTACTGATATGGGCGTCACACCACGCGGGCGAGCTGGCC
GCCCTCCTCGGCCTGAATGGGATCATACCACCGTTGCCGGCATGTTGCGCAATCCGGTGTACAAAGGGCAATACTACTCG
GCAGCGCATAATCTCTTTGTGCCAGTTCCAGCAATTGTAGACGCCGAGACATGGGAAGCGGTGCAAGAGCAATTGACGCG
CAATCAGGCAATGGCCAAGCGCAATGCTAAGCGCGTGTATTCGTTGCGCGGGCGGATACGGTGCGGGATATGCGGCAATC
GCATGTCAGGCAATGGCGCGGGCACACGTGCATCCGGCAAGACGTATCACTATTACATGTGTCACGCCGCCAAAGGCGCG
CTGATTGCATCGTGCAACCATGGCACATCGTACCGGGCCGAGCGGCTGGAAGCGTTGGTATGGCAATGGGTAATAGAAAC
GGTGTTGGATGAGACGCGACTAGTGCGAGCAATCGAGGCGGCCCGCGCCAATGAAGCCGGCCAGCGTGAGGCGCTGGAAC
ATGAGCGAGCTGCCTATGCACGCCAGATTGCCGAGGCAGGAACGCGCACGGCGCGGCTCATTGAATTGTATACCGCTGGT
GTATGCACATTGGATGAGGTCGCCGCCACCAAGAAACAATACGAACTGCAACGTCAAAGCGCTCAGCGCGAGCTTGACCG
AATCGATGCCCAGCTTGCCGCATTAAACAGCCACCATGCCAATCGTGACGCGCTGCTTGCGATGGCTCGCGCACTCAAAG
CGGCATTGCAGATTGAGGCAACGCCGGAAGAGCAAATGAAGGTCTATGAGGCGTTGGATGTGCAAGTGGTAGTGCGCGAG
AATAATATCGATGTGCGCGCAGTGCTTACCGGTGATGCCGGCACGTTTTTGATTGCGGGGGAACCAATAAGTTCAACCAG
ATGA

Upstream 100 bases:

>100_bases
TAATGGCAATGAGATGATTTTACCTACATTGTTGATTGCAATTTAACAACCTTGTGGTACAATCCTAGGAAAGTAATCAC
ACTCTGGCATGGAGGGGAAT

Downstream 100 bases:

>100_bases
AAAAGGTCACGGCTGTACCACCGTTACCGAGTGCCGCCAACCAATAGGTTGGTGTGTAGCGTTCACCCAGCGAGCGCAAC
CCCGTCAGACGAGCAACCAC

Product: Resolvase domain-containing protein

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MHAVIYARVSTEEQGDNFSIPAQLAACREYAERNGLQVVAECIDTMSGARLDRPGLQQVRDLVSQQLVQAVIVYHQDRLS
RNLAHFLYLRDEFQNARIALHFTTLGQARDTPEDKLIQNMIGSFAEHERLRIIERTKQGRRARLLSGKPLGLGNHPAYGY
HWHGTKHDRHLHINEAEAAIVRRIFAWALEGVPTQRIAKLLTDMGVTPRGRAGRPPRPEWDHTTVAGMLRNPVYKGQYYS
AAHNLFVPVPAIVDAETWEAVQEQLTRNQAMAKRNAKRVYSLRGRIRCGICGNRMSGNGAGTRASGKTYHYYMCHAAKGA
LIASCNHGTSYRAERLEALVWQWVIETVLDETRLVRAIEAARANEAGQREALEHERAAYARQIAEAGTRTARLIELYTAG
VCTLDEVAATKKQYELQRQSAQRELDRIDAQLAALNSHHANRDALLAMARALKAALQIEATPEEQMKVYEALDVQVVVRE
NNIDVRAVLTGDAGTFLIAGEPISSTR

Sequences:

>Translated_507_residues
MHAVIYARVSTEEQGDNFSIPAQLAACREYAERNGLQVVAECIDTMSGARLDRPGLQQVRDLVSQQLVQAVIVYHQDRLS
RNLAHFLYLRDEFQNARIALHFTTLGQARDTPEDKLIQNMIGSFAEHERLRIIERTKQGRRARLLSGKPLGLGNHPAYGY
HWHGTKHDRHLHINEAEAAIVRRIFAWALEGVPTQRIAKLLTDMGVTPRGRAGRPPRPEWDHTTVAGMLRNPVYKGQYYS
AAHNLFVPVPAIVDAETWEAVQEQLTRNQAMAKRNAKRVYSLRGRIRCGICGNRMSGNGAGTRASGKTYHYYMCHAAKGA
LIASCNHGTSYRAERLEALVWQWVIETVLDETRLVRAIEAARANEAGQREALEHERAAYARQIAEAGTRTARLIELYTAG
VCTLDEVAATKKQYELQRQSAQRELDRIDAQLAALNSHHANRDALLAMARALKAALQIEATPEEQMKVYEALDVQVVVRE
NNIDVRAVLTGDAGTFLIAGEPISSTR
>Mature_507_residues
MHAVIYARVSTEEQGDNFSIPAQLAACREYAERNGLQVVAECIDTMSGARLDRPGLQQVRDLVSQQLVQAVIVYHQDRLS
RNLAHFLYLRDEFQNARIALHFTTLGQARDTPEDKLIQNMIGSFAEHERLRIIERTKQGRRARLLSGKPLGLGNHPAYGY
HWHGTKHDRHLHINEAEAAIVRRIFAWALEGVPTQRIAKLLTDMGVTPRGRAGRPPRPEWDHTTVAGMLRNPVYKGQYYS
AAHNLFVPVPAIVDAETWEAVQEQLTRNQAMAKRNAKRVYSLRGRIRCGICGNRMSGNGAGTRASGKTYHYYMCHAAKGA
LIASCNHGTSYRAERLEALVWQWVIETVLDETRLVRAIEAARANEAGQREALEHERAAYARQIAEAGTRTARLIELYTAG
VCTLDEVAATKKQYELQRQSAQRELDRIDAQLAALNSHHANRDALLAMARALKAALQIEATPEEQMKVYEALDVQVVVRE
NNIDVRAVLTGDAGTFLIAGEPISSTR

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 56786; Mature: 56786

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00397 RECOMBINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAVIYARVSTEEQGDNFSIPAQLAACREYAERNGLQVVAECIDTMSGARLDRPGLQQVR
CCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHH
DLVSQQLVQAVIVYHQDRLSRNLAHFLYLRDEFQNARIALHFTTLGQARDTPEDKLIQNM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHH
IGSFAEHERLRIIERTKQGRRARLLSGKPLGLGNHPAYGYHWHGTKHDRHLHINEAEAAI
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEECCCCCCCCEEECCHHHHHH
VRRIFAWALEGVPTQRIAKLLTDMGVTPRGRAGRPPRPEWDHTTVAGMLRNPVYKGQYYS
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHH
AAHNLFVPVPAIVDAETWEAVQEQLTRNQAMAKRNAKRVYSLRGRIRCGICGNRMSGNGA
HHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
GTRASGKTYHYYMCHAAKGALIASCNHGTSYRAERLEALVWQWVIETVLDETRLVRAIEA
CCCCCCCEEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARANEAGQREALEHERAAYARQIAEAGTRTARLIELYTAGVCTLDEVAATKKQYELQRQS
HHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AQRELDRIDAQLAALNSHHANRDALLAMARALKAALQIEATPEEQMKVYEALDVQVVVRE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCEEEEEEE
NNIDVRAVLTGDAGTFLIAGEPISSTR
CCCEEEEEEECCCCEEEEECCCCCCCC
>Mature Secondary Structure
MHAVIYARVSTEEQGDNFSIPAQLAACREYAERNGLQVVAECIDTMSGARLDRPGLQQVR
CCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHH
DLVSQQLVQAVIVYHQDRLSRNLAHFLYLRDEFQNARIALHFTTLGQARDTPEDKLIQNM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHH
IGSFAEHERLRIIERTKQGRRARLLSGKPLGLGNHPAYGYHWHGTKHDRHLHINEAEAAI
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEECCCCCCCCEEECCHHHHHH
VRRIFAWALEGVPTQRIAKLLTDMGVTPRGRAGRPPRPEWDHTTVAGMLRNPVYKGQYYS
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHH
AAHNLFVPVPAIVDAETWEAVQEQLTRNQAMAKRNAKRVYSLRGRIRCGICGNRMSGNGA
HHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
GTRASGKTYHYYMCHAAKGALIASCNHGTSYRAERLEALVWQWVIETVLDETRLVRAIEA
CCCCCCCEEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARANEAGQREALEHERAAYARQIAEAGTRTARLIELYTAGVCTLDEVAATKKQYELQRQS
HHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AQRELDRIDAQLAALNSHHANRDALLAMARALKAALQIEATPEEQMKVYEALDVQVVVRE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCEEEEEEE
NNIDVRAVLTGDAGTFLIAGEPISSTR
CCCEEEEEEECCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]