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The map label for this gene is gmhA [H]

Identifier: 222523593

GI number: 222523593

Start: 363221

End: 363799

Strand: Direct

Name: gmhA [H]

Synonym: Chy400_0299

Alternate gene names: 222523593

Gene position: 363221-363799 (Clockwise)

Preceding gene: 222523592

Following gene: 222523594

Centisome position: 6.89

GC content: 53.37

Gene sequence:

>579_bases
ATGTCATTCCAACAGCAACTTGATGAAGCCATTACGGTTTTACAGGCATGCACGACCCTGGCACCGGCCATCGACCGGAT
CACAGAGCTGGTGGCCGATGCAATACTGAGTGGACACACGTTATACACTGCGGGAAACGGAGGAAGTGCGGCAGATGCTA
TGCATCTGGCCGAAGAGTTAATCGGACGATACCGCCATAACCGCCGACCATTGCCGGCAATCTGCCTGAACGCCGATGTC
GGTGCAATGACCTGTATTGCCAACGACTTTGGCTACGATGAGGTCTTTGCCCGTCAACTGACGGCGTTGGGCAAACCTGG
TGATGTGTTAATTGTGTTCAGTACAAGTGGCAATTCGCCCAACATTATTAACGCGCTGAGTACAGCCCGTGCCAGAGGTA
TGATTAACATTGCCCTGCTCGGCAAAGATGGTGGTATGGCCCGTAATCTGGCCGATCACGCTCTGATCGTGCCGAGCCAG
AATACTGCGCGTATTCAGGAAGTTCACACCCTCTTTCTGCATGCCATCTGCGAGCAGGTCGAACAACGTCTTGCCAGTGC
TAGCGAGCCATACGTTTGA

Upstream 100 bases:

>100_bases
AGATTGATGAAAGAGCGTCCAGTCACTCTCGCCCACAGCCGACGTGCTATGTAACGACAGCGCGTATAATAGGCGCGAGA
TTATCACCTACGGAGAGATT

Downstream 100 bases:

>100_bases
GAGGAGTCTATGAACCGGATTCTTGTTACTGAAAAGATCGCTGCCGAAGGACTTGCGGTGTTGCGTCAGGCCGGGACAGT
GGATGTTCGGCTTGATCTCG

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MSFQQQLDEAITVLQACTTLAPAIDRITELVADAILSGHTLYTAGNGGSAADAMHLAEELIGRYRHNRRPLPAICLNADV
GAMTCIANDFGYDEVFARQLTALGKPGDVLIVFSTSGNSPNIINALSTARARGMINIALLGKDGGMARNLADHALIVPSQ
NTARIQEVHTLFLHAICEQVEQRLASASEPYV

Sequences:

>Translated_192_residues
MSFQQQLDEAITVLQACTTLAPAIDRITELVADAILSGHTLYTAGNGGSAADAMHLAEELIGRYRHNRRPLPAICLNADV
GAMTCIANDFGYDEVFARQLTALGKPGDVLIVFSTSGNSPNIINALSTARARGMINIALLGKDGGMARNLADHALIVPSQ
NTARIQEVHTLFLHAICEQVEQRLASASEPYV
>Mature_191_residues
SFQQQLDEAITVLQACTTLAPAIDRITELVADAILSGHTLYTAGNGGSAADAMHLAEELIGRYRHNRRPLPAICLNADVG
AMTCIANDFGYDEVFARQLTALGKPGDVLIVFSTSGNSPNIINALSTARARGMINIALLGKDGGMARNLADHALIVPSQN
TARIQEVHTLFLHAICEQVEQRLASASEPYV

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=163, Percent_Identity=46.6257668711656, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1789539, Length=176, Percent_Identity=41.4772727272727, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20498; Mature: 20366

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFQQQLDEAITVLQACTTLAPAIDRITELVADAILSGHTLYTAGNGGSAADAMHLAEEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHH
IGRYRHNRRPLPAICLNADVGAMTCIANDFGYDEVFARQLTALGKPGDVLIVFSTSGNSP
HHHHHHCCCCCCEEEECCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCC
NIINALSTARARGMINIALLGKDGGMARNLADHALIVPSQNTARIQEVHTLFLHAICEQV
HHHHHHHHHHHCCEEEEEEEECCCCCHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
EQRLASASEPYV
HHHHHCCCCCCC
>Mature Secondary Structure 
SFQQQLDEAITVLQACTTLAPAIDRITELVADAILSGHTLYTAGNGGSAADAMHLAEEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHH
IGRYRHNRRPLPAICLNADVGAMTCIANDFGYDEVFARQLTALGKPGDVLIVFSTSGNSP
HHHHHHCCCCCCEEEECCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCC
NIINALSTARARGMINIALLGKDGGMARNLADHALIVPSQNTARIQEVHTLFLHAICEQV
HHHHHHHHHHHCCEEEEEEEECCCCCHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
EQRLASASEPYV
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]