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The map label for this gene is fmt

Identifier: 222523337

GI number: 222523337

Start: 39476

End: 40408

Strand: Direct

Name: fmt

Synonym: Chy400_0038

Alternate gene names: 222523337

Gene position: 39476-40408 (Clockwise)

Preceding gene: 222523330

Following gene: 222523338

Centisome position: 0.75

GC content: 57.34

Gene sequence:

>933_bases
ATGCGTATTTTATTTCTGGGCAGTCCATCATTCGCCGTTCACGCATTAGAGGCATTAGTTGCCGCCGGACACGAGATTGT
CGGTGTTGTAACGCAACCAGACCGACCGGCCGGTCGTGACCGCCGGCTGACACCACCACCGGTAAAGATTGCAGCAATGG
CCCATAACCTGCCGGTGCTCCAACCAGAGACATTGCGCGATCCGACAGTGGTTGAGACGTTGAGCGCTCTGCAACCAGAA
GTTGGGGTCGTCGCTGCCTACGGTGAAATTCTACGTCGGGCTGTGTTGAGTATTCCGCCATTGGGGTATCTCAACATCCA
TCCATCGCTGCTGCCGCTATACCGTGGCCCTACCCCGGTAGCGGGCGCTATCCTGGCCGGAGAGACGGTAACCGGTGTGA
CGATTATGTTGCTCGATCCCAGTATGGATAGCGGACCGATCCTGGCTCAGGCTGTCGTTGATCTGCCACCAACCGCACGC
GCCGGTCAATTGACCGATGAACTCTTTCGGATTGGCGCCGATTTGCTGGTGCAAGTGTTGCCACGCTATGCCCGTGGCGA
GATTGAGCCTCGTCCACAAGATCACAGTCGGGCGACCGTGACTAAGATGCTGAAAAAAGAGGACGGTCGTATCGATTGGT
CGTTACCGGCGATAGTGATTGAACGGATGACGAGGGCTTATGATCCGTGGCCTGGTGCTTATACCTTTTGGCGTGGTCAA
CCACTGCGTATTATCAAAGCGGCGGTAGCTTCGGCTGACGGTACAAACGTGCCGGGTACCGTTATTGGGCGTAGTGGCAG
TGGGCATCCACTGGTGCAAACTGGCAGTGATGCCCTGGAGCTGATTGAAGTCCAGCCGGCCAGTCGCCGCCCCATGAGTG
GCTCAGCCTGGCTGGCCGGTGTTCATGCTGACAACATCCGGCTAGGGGAGTAG

Upstream 100 bases:

>100_bases
GCCAGTAAATTCAGACTCAGCAATAGCAGGTAAAAAGCTGCATCATTTATGTTGTTCACCTCTGTTATTCTGTAGCGATT
TCTAGCTGAAAAGGGATGAC

Downstream 100 bases:

>100_bases
CACCAGCCTGTTCGCCTTAGAACCCACCCGTAATCCGTGTATTTGATGGGTAGGAGCTATTTCGTCCATCCACGCAGACA
TTACGACATCTTCCACGCTC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MRILFLGSPSFAVHALEALVAAGHEIVGVVTQPDRPAGRDRRLTPPPVKIAAMAHNLPVLQPETLRDPTVVETLSALQPE
VGVVAAYGEILRRAVLSIPPLGYLNIHPSLLPLYRGPTPVAGAILAGETVTGVTIMLLDPSMDSGPILAQAVVDLPPTAR
AGQLTDELFRIGADLLVQVLPRYARGEIEPRPQDHSRATVTKMLKKEDGRIDWSLPAIVIERMTRAYDPWPGAYTFWRGQ
PLRIIKAAVASADGTNVPGTVIGRSGSGHPLVQTGSDALELIEVQPASRRPMSGSAWLAGVHADNIRLGE

Sequences:

>Translated_310_residues
MRILFLGSPSFAVHALEALVAAGHEIVGVVTQPDRPAGRDRRLTPPPVKIAAMAHNLPVLQPETLRDPTVVETLSALQPE
VGVVAAYGEILRRAVLSIPPLGYLNIHPSLLPLYRGPTPVAGAILAGETVTGVTIMLLDPSMDSGPILAQAVVDLPPTAR
AGQLTDELFRIGADLLVQVLPRYARGEIEPRPQDHSRATVTKMLKKEDGRIDWSLPAIVIERMTRAYDPWPGAYTFWRGQ
PLRIIKAAVASADGTNVPGTVIGRSGSGHPLVQTGSDALELIEVQPASRRPMSGSAWLAGVHADNIRLGE
>Mature_310_residues
MRILFLGSPSFAVHALEALVAAGHEIVGVVTQPDRPAGRDRRLTPPPVKIAAMAHNLPVLQPETLRDPTVVETLSALQPE
VGVVAAYGEILRRAVLSIPPLGYLNIHPSLLPLYRGPTPVAGAILAGETVTGVTIMLLDPSMDSGPILAQAVVDLPPTAR
AGQLTDELFRIGADLLVQVLPRYARGEIEPRPQDHSRATVTKMLKKEDGRIDWSLPAIVIERMTRAYDPWPGAYTFWRGQ
PLRIIKAAVASADGTNVPGTVIGRSGSGHPLVQTGSDALELIEVQPASRRPMSGSAWLAGVHADNIRLGE

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family

Homologues:

Organism=Homo sapiens, GI164663775, Length=255, Percent_Identity=34.9019607843137, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI21614513, Length=328, Percent_Identity=27.1341463414634, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI238814322, Length=337, Percent_Identity=25.2225519287834, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1789683, Length=293, Percent_Identity=42.320819112628, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI1788589, Length=297, Percent_Identity=31.6498316498317, Blast_Score=136, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI133930964, Length=260, Percent_Identity=25, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319458, Length=265, Percent_Identity=28.3018867924528, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45550868, Length=304, Percent_Identity=29.6052631578947, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28571984, Length=279, Percent_Identity=29.3906810035842, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24585660, Length=241, Percent_Identity=26.9709543568465, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): FMT_CHLAA (A9WAR0)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001633677.1
- ProteinModelPortal:   A9WAR0
- SMR:   A9WAR0
- GeneID:   5828183
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_0033
- HOGENOM:   HBG571560
- OMA:   IMQMDEG
- ProtClustDB:   CLSK975056
- HAMAP:   MF_00182
- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518
- Gene3D:   G3DSA:3.10.25.10
- Gene3D:   G3DSA:3.40.50.170
- PANTHER:   PTHR11138
- TIGRFAMs:   TIGR00460

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N; SSF50486 FMT_C_like; SSF53328 formyl_transf

EC number: =2.1.2.9

Molecular weight: Translated: 33138; Mature: 33138

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILFLGSPSFAVHALEALVAAGHEIVGVVTQPDRPAGRDRRLTPPPVKIAAMAHNLPVL
CEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCC
QPETLRDPTVVETLSALQPEVGVVAAYGEILRRAVLSIPPLGYLNIHPSLLPLYRGPTPV
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCEEECCCCCCCH
AGAILAGETVTGVTIMLLDPSMDSGPILAQAVVDLPPTARAGQLTDELFRIGADLLVQVL
HHHEEECCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
PRYARGEIEPRPQDHSRATVTKMLKKEDGRIDWSLPAIVIERMTRAYDPWPGAYTFWRGQ
HHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHCCCCCCCEEEECCC
PLRIIKAAVASADGTNVPGTVIGRSGSGHPLVQTGSDALELIEVQPASRRPMSGSAWLAG
HHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEECCCCCEEEEEECCCCCCCCCCCCEEEE
VHADNIRLGE
EECCCEEECC
>Mature Secondary Structure
MRILFLGSPSFAVHALEALVAAGHEIVGVVTQPDRPAGRDRRLTPPPVKIAAMAHNLPVL
CEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCC
QPETLRDPTVVETLSALQPEVGVVAAYGEILRRAVLSIPPLGYLNIHPSLLPLYRGPTPV
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCEEECCCCCCCH
AGAILAGETVTGVTIMLLDPSMDSGPILAQAVVDLPPTARAGQLTDELFRIGADLLVQVL
HHHEEECCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
PRYARGEIEPRPQDHSRATVTKMLKKEDGRIDWSLPAIVIERMTRAYDPWPGAYTFWRGQ
HHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHCCCCCCCEEEECCC
PLRIIKAAVASADGTNVPGTVIGRSGSGHPLVQTGSDALELIEVQPASRRPMSGSAWLAG
HHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEECCCCCEEEEEECCCCCCCCCCCCEEEE
VHADNIRLGE
EECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA