Click here to switch to the map view.

The map label for this gene is pbuO [H]

Identifier: 222094449

GI number: 222094449

Start: 766433

End: 767725

Strand: Direct

Name: pbuO [H]

Synonym: BCQ_0763

Alternate gene names: 222094449

Gene position: 766433-767725 (Clockwise)

Preceding gene: 222094446

Following gene: 222094450

Centisome position: 14.7

GC content: 35.42

Gene sequence:

>1293_bases
ATGTTTCAATTACAAAAATATAACACTTCTGTGAAGCAAGAGCTTTTAGCTGGCATCACAACTTTTTTTACATTTGCGTA
TATTCTTGTCATCAATCCGAAAATATTATCTGATGCAGGTGTACCATTTGATCAAGCTTTTACGGCAACTATTATTGCGA
CTGTTGTAGGGACGTTATGTATGTCGTTTTTAGCTAACTATCCAATTGTTATTGCTCCAGCTATGGGAATGAATGCGTAT
TTTGCTTATTCTGTTGTTCAACAGGCAGAGGGGATTACATATGTCATTGCGTTTTCAGCAGTATTTGTAACAGGTATCAT
TTTTCTTTTATTATCTTTCACTTCATTTAGGCAAAAGCTAATTGTCGCAATTCCTGACAGTTTAAAACATGCAATTGCAG
GTGGAATTGGGTTATTTATTGCTTTTATTGGATTACGTCTATCTGGAATTATCGTTGATCATCCATCTAATTTAGTTACG
ATTGGTGATTTCCATTCTCCAGCCGTTATTTTAACTTTAATTGGTTTGATTTTAGCGGCGGTATTAATGACATTGCGTGT
GAGCGGTGCATTATTTATTAGTATGATTGTGACAGGAATTATCGCCTTCTTTACAGGGCAGCTGAAGTTTACGGATAAAA
TTGTTGCGATGCCTCATTTACCAGAGGGGATTATCGTTTCAAATCCAATCAACGCCTTTTCAGATGTAATTGAATACGGA
TTATATGGCGTTGTATTTTCATTTTTACTTGTACTGTTATTTGATACAACAGGAGCATTACTCGGTTTAATTAAACAAGC
AGGTTTAATTACAGATAATACAGAGAAACGTTTTGGTAAAGCATTTATTGCGGATGCAATTGGCGGTACTACAGGCTCTA
TCTTTGGGACAAGCCCAACAGCAGCGACGATTGAATCGTCAGCTGGTATTGCTGCAGGTGGTAAAACAGGATTAACAGGT
ATTGTAGTAGTCGGCCTAACGATTATAACAGCATTCTTTAGCCCTGTTATTGCTTCTTTATCAAGTGTAGCCGCTATTAC
AGCTCCTTCATTAATTATTGTAGGTAGTTTAATGGCACAAAGTATTCGTGATATTAATTGGAATGAATTTGAAGATGCAT
TACCAGCATTTTTAATTTTCGTTGGTATTCCGTTAACGTCTAGTATTGCGAATGGAATTGCAATTGGGTTTTTAGTGTAT
CCAGTCTTAAAAATTGTGAAAGGGAAAGGGATGGAAGTACATCCATTACTATACTTATTTACAATTTTATTTGGATGTCA
TTTATTCTTATAA

Upstream 100 bases:

>100_bases
TTCTTTTTATTGATTGTTAAGATTAAGTATTATATTTTCTCACATACTAGTAAGAAAAGAATGTGTGATAATAATTCAGA
TGTAGGAAGGGTACATAACC

Downstream 100 bases:

>100_bases
TATAGAAATAGGAGAGGGGGCTTCTTATGAGGGGCTCCTTTTTTGTGTATAATAAAGTGAAACTATAATCAGTGGGGGTT
CTGTTCATCCCCCACTGATT

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MFQLQKYNTSVKQELLAGITTFFTFAYILVINPKILSDAGVPFDQAFTATIIATVVGTLCMSFLANYPIVIAPAMGMNAY
FAYSVVQQAEGITYVIAFSAVFVTGIIFLLLSFTSFRQKLIVAIPDSLKHAIAGGIGLFIAFIGLRLSGIIVDHPSNLVT
IGDFHSPAVILTLIGLILAAVLMTLRVSGALFISMIVTGIIAFFTGQLKFTDKIVAMPHLPEGIIVSNPINAFSDVIEYG
LYGVVFSFLLVLLFDTTGALLGLIKQAGLITDNTEKRFGKAFIADAIGGTTGSIFGTSPTAATIESSAGIAAGGKTGLTG
IVVVGLTIITAFFSPVIASLSSVAAITAPSLIIVGSLMAQSIRDINWNEFEDALPAFLIFVGIPLTSSIANGIAIGFLVY
PVLKIVKGKGMEVHPLLYLFTILFGCHLFL

Sequences:

>Translated_430_residues
MFQLQKYNTSVKQELLAGITTFFTFAYILVINPKILSDAGVPFDQAFTATIIATVVGTLCMSFLANYPIVIAPAMGMNAY
FAYSVVQQAEGITYVIAFSAVFVTGIIFLLLSFTSFRQKLIVAIPDSLKHAIAGGIGLFIAFIGLRLSGIIVDHPSNLVT
IGDFHSPAVILTLIGLILAAVLMTLRVSGALFISMIVTGIIAFFTGQLKFTDKIVAMPHLPEGIIVSNPINAFSDVIEYG
LYGVVFSFLLVLLFDTTGALLGLIKQAGLITDNTEKRFGKAFIADAIGGTTGSIFGTSPTAATIESSAGIAAGGKTGLTG
IVVVGLTIITAFFSPVIASLSSVAAITAPSLIIVGSLMAQSIRDINWNEFEDALPAFLIFVGIPLTSSIANGIAIGFLVY
PVLKIVKGKGMEVHPLLYLFTILFGCHLFL
>Mature_430_residues
MFQLQKYNTSVKQELLAGITTFFTFAYILVINPKILSDAGVPFDQAFTATIIATVVGTLCMSFLANYPIVIAPAMGMNAY
FAYSVVQQAEGITYVIAFSAVFVTGIIFLLLSFTSFRQKLIVAIPDSLKHAIAGGIGLFIAFIGLRLSGIIVDHPSNLVT
IGDFHSPAVILTLIGLILAAVLMTLRVSGALFISMIVTGIIAFFTGQLKFTDKIVAMPHLPEGIIVSNPINAFSDVIEYG
LYGVVFSFLLVLLFDTTGALLGLIKQAGLITDNTEKRFGKAFIADAIGGTTGSIFGTSPTAATIESSAGIAAGGKTGLTG
IVVVGLTIITAFFSPVIASLSSVAAITAPSLIIVGSLMAQSIRDINWNEFEDALPAFLIFVGIPLTSSIANGIAIGFLVY
PVLKIVKGKGMEVHPLLYLFTILFGCHLFL

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=424, Percent_Identity=38.2075471698113, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI87082309, Length=431, Percent_Identity=37.122969837587, Blast_Score=271, Evalue=8e-74,
Organism=Escherichia coli, GI1790499, Length=425, Percent_Identity=31.2941176470588, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI48994909, Length=412, Percent_Identity=33.0097087378641, Blast_Score=176, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45458; Mature: 45458

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQLQKYNTSVKQELLAGITTFFTFAYILVINPKILSDAGVPFDQAFTATIIATVVGTLC
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
MSFLANYPIVIAPAMGMNAYFAYSVVQQAEGITYVIAFSAVFVTGIIFLLLSFTSFRQKL
HHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHE
IVAIPDSLKHAIAGGIGLFIAFIGLRLSGIIVDHPSNLVTIGDFHSPAVILTLIGLILAA
EEECCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCEEEECCCCCHHHHHHHHHHHHHH
VLMTLRVSGALFISMIVTGIIAFFTGQLKFTDKIVAMPHLPEGIIVSNPINAFSDVIEYG
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEECCCCCCCCEECCCHHHHHHHHHHH
LYGVVFSFLLVLLFDTTGALLGLIKQAGLITDNTEKRFGKAFIADAIGGTTGSIFGTSPT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
AATIESSAGIAAGGKTGLTGIVVVGLTIITAFFSPVIASLSSVAAITAPSLIIVGSLMAQ
CHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SIRDINWNEFEDALPAFLIFVGIPLTSSIANGIAIGFLVYPVLKIVKGKGMEVHPLLYLF
HHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
TILFGCHLFL
HHHHHHHHCC
>Mature Secondary Structure
MFQLQKYNTSVKQELLAGITTFFTFAYILVINPKILSDAGVPFDQAFTATIIATVVGTLC
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
MSFLANYPIVIAPAMGMNAYFAYSVVQQAEGITYVIAFSAVFVTGIIFLLLSFTSFRQKL
HHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHE
IVAIPDSLKHAIAGGIGLFIAFIGLRLSGIIVDHPSNLVTIGDFHSPAVILTLIGLILAA
EEECCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCEEEECCCCCHHHHHHHHHHHHHH
VLMTLRVSGALFISMIVTGIIAFFTGQLKFTDKIVAMPHLPEGIIVSNPINAFSDVIEYG
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEECCCCCCCCEECCCHHHHHHHHHHH
LYGVVFSFLLVLLFDTTGALLGLIKQAGLITDNTEKRFGKAFIADAIGGTTGSIFGTSPT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
AATIESSAGIAAGGKTGLTGIVVVGLTIITAFFSPVIASLSSVAAITAPSLIIVGSLMAQ
CHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SIRDINWNEFEDALPAFLIFVGIPLTSSIANGIAIGFLVYPVLKIVKGKGMEVHPLLYLF
HHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
TILFGCHLFL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 11591660 [H]