Click here to switch to the map view.

The map label for this gene is treR [H]

Identifier: 222094382

GI number: 222094382

Start: 695292

End: 696002

Strand: Direct

Name: treR [H]

Synonym: BCQ_0696

Alternate gene names: 222094382

Gene position: 695292-696002 (Clockwise)

Preceding gene: 222094380

Following gene: 222094383

Centisome position: 13.33

GC content: 33.47

Gene sequence:

>711_bases
ATGATGAGTAAGTATGAACAAATTTATACAGAAATCAGTAATTCTATTGATAATAGGCAATTAAAAGAGGGATGCAAAAT
CCCATCAGAAACTGAATTAATGAAGCAATATGAAGCGAGCCGCGGTACTGTAAGAAAAGCTGTAGATTTATTACAAGAAC
GTGGATATGTTCAAAAAATACACGGAAAAGGTGTTTTTGTTTTAAAGCGAAAAAACATTGAATTCAACTTTGGTGGTATT
GTAAGTTTCCAAGAAGAAAATGAACGTTTAGGACGCCATTGTATTACAGAAGTCGTGGAAATGGAGAAAGTAAAAGCGAC
AAAAGAGGTTGCAAAGCTATTAAATGTGAAAGAGAAAACAGACATAGATCATATTAAACGCGTACGAAATATTGATGGAG
AAAAAGTAATTTTGGATATTAATCATTTTGTATCGGAATATATTCCTGGATTAACGAGTGAAATTGCAGCGGGGTCTATT
TATAAATATATTGAGAAAGAACTAGGTCTTCATATTAGTTACTCACAGAGAGTAATTGAAGTGCAACCATGTACAGAGGA
CGATAGAAAGTATTTAGATTTAAATGGAACAGATTATGTTGTTGTCGTGAAAAACTTTACGCATTTGTATGATGGAAGTC
AGTTCGAATATACAGAATCCCGCCACCGCTTAGATATTTTTCATTTTTCGGATGTGGCGCGGAGAAAATAA

Upstream 100 bases:

>100_bases
CTTTATTTTTCCTATACTGGAAAATAAGTGAGAGATTGGCAGAAGAGTGTAGCATGGTATAATACATATAGAACTAGAAG
GTGACAAGGGGCTATTGTAG

Downstream 100 bases:

>100_bases
GGAGATGGAACGTAATGTTTCATCTCTTTTTTTATAAAAAAACGACAAACTCGTATATACGAGTGTTGACTAACTTATAT
ATACGAGTTAATATGTAATT

Product: trehalose operon transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MMSKYEQIYTEISNSIDNRQLKEGCKIPSETELMKQYEASRGTVRKAVDLLQERGYVQKIHGKGVFVLKRKNIEFNFGGI
VSFQEENERLGRHCITEVVEMEKVKATKEVAKLLNVKEKTDIDHIKRVRNIDGEKVILDINHFVSEYIPGLTSEIAAGSI
YKYIEKELGLHISYSQRVIEVQPCTEDDRKYLDLNGTDYVVVVKNFTHLYDGSQFEYTESRHRLDIFHFSDVARRK

Sequences:

>Translated_236_residues
MMSKYEQIYTEISNSIDNRQLKEGCKIPSETELMKQYEASRGTVRKAVDLLQERGYVQKIHGKGVFVLKRKNIEFNFGGI
VSFQEENERLGRHCITEVVEMEKVKATKEVAKLLNVKEKTDIDHIKRVRNIDGEKVILDINHFVSEYIPGLTSEIAAGSI
YKYIEKELGLHISYSQRVIEVQPCTEDDRKYLDLNGTDYVVVVKNFTHLYDGSQFEYTESRHRLDIFHFSDVARRK
>Mature_236_residues
MMSKYEQIYTEISNSIDNRQLKEGCKIPSETELMKQYEASRGTVRKAVDLLQERGYVQKIHGKGVFVLKRKNIEFNFGGI
VSFQEENERLGRHCITEVVEMEKVKATKEVAKLLNVKEKTDIDHIKRVRNIDGEKVILDINHFVSEYIPGLTSEIAAGSI
YKYIEKELGLHISYSQRVIEVQPCTEDDRKYLDLNGTDYVVVVKNFTHLYDGSQFEYTESRHRLDIFHFSDVARRK

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=236, Percent_Identity=29.2372881355932, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1790540, Length=233, Percent_Identity=24.4635193133047, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1790118, Length=168, Percent_Identity=26.7857142857143, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082252, Length=172, Percent_Identity=27.3255813953488, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27488; Mature: 27488

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSKYEQIYTEISNSIDNRQLKEGCKIPSETELMKQYEASRGTVRKAVDLLQERGYVQKI
CCCHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEE
HGKGVFVLKRKNIEFNFGGIVSFQEENERLGRHCITEVVEMEKVKATKEVAKLLNVKEKT
CCCCEEEEEECCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCC
DIDHIKRVRNIDGEKVILDINHFVSEYIPGLTSEIAAGSIYKYIEKELGLHISYSQRVIE
CHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCEEEECCCEEEE
VQPCTEDDRKYLDLNGTDYVVVVKNFTHLYDGSQFEYTESRHRLDIFHFSDVARRK
EECCCCCCCEEEECCCCCEEEEEECCHHHHCCCCCCCCCCCCEEEEEEHHHHHHCC
>Mature Secondary Structure
MMSKYEQIYTEISNSIDNRQLKEGCKIPSETELMKQYEASRGTVRKAVDLLQERGYVQKI
CCCHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEE
HGKGVFVLKRKNIEFNFGGIVSFQEENERLGRHCITEVVEMEKVKATKEVAKLLNVKEKT
CCCCEEEEEECCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCC
DIDHIKRVRNIDGEKVILDINHFVSEYIPGLTSEIAAGSIYKYIEKELGLHISYSQRVIE
CHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCEEEECCCEEEE
VQPCTEDDRKYLDLNGTDYVVVVKNFTHLYDGSQFEYTESRHRLDIFHFSDVARRK
EECCCCCCCEEEECCCCCEEEEEECCHHHHCCCCCCCCCCCCEEEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]