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The map label for this gene is rsmB [H]

Identifier: 221232467

GI number: 221232467

Start: 1677118

End: 1678431

Strand: Reverse

Name: rsmB [H]

Synonym: SPN23F_17370

Alternate gene names: 221232467

Gene position: 1678431-1677118 (Counterclockwise)

Preceding gene: 221232468

Following gene: 221232466

Centisome position: 75.56

GC content: 44.44

Gene sequence:

>1314_bases
GTGACTAAAGTAGAAACGGCTAGAAGTTTAGCTCTAGCAGTGCTAGAGGATGTTTTTGTGAACCAAGCATACTCAAATAT
CGCCTTAAATAAGCATCTAAAGGGGAGTCAACTTTTGGCAGCAGACAAGGGCTTAGTGACCGAGCTGGTCTATGGAACGG
TAGCCCGTAAACTGACTCTGGAATGGTACCTATCCCACTTTATCGAAGACAGAGACCAGTTAGACAGCTGGCTCTATGTC
CTTCTTCTCATGAGTGCCTACCAACTCCGCTATTTGGACAAGATTCCAGATCATGCTGTGGTCAATGAAGCAGTGGAATT
GGCCAAACTTCGTAAAAAAGGCAGTGAAAAATTGGTCAATGCCCTCCTTCGCCGTATCTTGCGTGAAGGCTGGCCAGATA
TTGCTAGCATCAAGCGAAAAAACAAGCGTGACTCCATTGCCTATTCTCTCCCAGTTTGGCTAGTTGCCAAACTCAAGGAA
GAATACGGAGAGGAGAGAGCAAAAGCCATCTTTGAAAGCCTGTTAGTGCGAAACAAAGCCAGTATTCGTGTAACAGACCT
AAGTCGAAAAGAGGAAATCCAAGCCTTGTTGGAGGCGAATGATTCCCTTTTAGCAACCACTGGTCTGGTTAAGGAGCAGG
GGCATTTTGCAGGGCATAATTTGTTTGCGGATGGAGCCATTACCATCCAAGACGAGTCCAGTCAGCTGGTTGCTCCGACG
CTTGATTTACAAGGTGATGAGCGAGTGCTTGATGCCTGTGCGGCTCCAGGTGGGAAAACAGCCCATATAGCCTCTTATCT
TACGACAGGTCAGGTTACTGCTCTGGACTTGTACGACCACAAGTTGGATTTAATTCAAGAAAATGCCCAACGTCTGGGAG
TTGAAGATCGGGTTCAAACTCAAAAATTGGATGCCAGAAAGGTGCATGAGTTTTTTGACCAGGATTCCTTTGATAAGATT
TTGGTGGATGCTCCTTGTTCAGGAATCGGTCTTTTGCGCCGAAAACCAGATATCAAATACAATAAAGAAACGGCAGATTT
CGCGTCCTTGCAGGAAATTCAGTTAGAAATATTAGGTAGTGTTTGTCAAATACTAGGCAAAGGTGGTATAATAACTTATA
GCACCTGCACTATCGTCTCAGAGGAGAATTTTCAAGTCGTTAAGGCCTTTTTAGAGAGTCATCCCGAGTTCGAGCAGGTA
AAACTAGAACATGAATGTAAGGATATCATGAAAGACGGCTGTATCCTCATTACACCTGAATTGTATGGAAGTGATGGATT
CTTCATCAGTCAATTTCGCAAGATATCGGATTAG

Upstream 100 bases:

>100_bases
CTATCCCTCAAACAAGTGCAGCCAGCTGGTAAGCCTAAGATGGACATTGCTTCCTTCCTCAACGGAGTTGGACGTACATT
GACTGTAGGAGAACGATTTG

Downstream 100 bases:

>100_bases
GAAGGAACTGACACATGGAAATTTCATTATTAACAGATGTTGGTCAGAAACGAACAAATAACCAAGACTATGTCAACCAC
TATGTCAATAGAGCTGGACG

Product: ribosomal RNA small subunit methyltransferase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKGLVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYV
LLLMSAYQLRYLDKIPDHAVVNEAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAGHNLFADGAITIQDESSQLVAPT
LDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALDLYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKI
LVDAPCSGIGLLRRKPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLESHPEFEQV
KLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD

Sequences:

>Translated_437_residues
MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKGLVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYV
LLLMSAYQLRYLDKIPDHAVVNEAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAGHNLFADGAITIQDESSQLVAPT
LDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALDLYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKI
LVDAPCSGIGLLRRKPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLESHPEFEQV
KLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD
>Mature_436_residues
TKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKGLVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVL
LLMSAYQLRYLDKIPDHAVVNEAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKEE
YGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAGHNLFADGAITIQDESSQLVAPTL
DLQGDERVLDACAAPGGKTAHIASYLTTGQVTALDLYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKIL
VDAPCSGIGLLRRKPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLESHPEFEQVK
LEHECKDIMKDGCILITPELYGSDGFFISQFRKISD

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=223, Percent_Identity=34.9775784753363, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI76150625, Length=333, Percent_Identity=29.7297297297297, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI76150623, Length=333, Percent_Identity=29.7297297297297, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI8922322, Length=257, Percent_Identity=28.0155642023346, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI23199998, Length=257, Percent_Identity=28.0155642023346, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI270288816, Length=257, Percent_Identity=28.0155642023346, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI270288818, Length=257, Percent_Identity=28.0155642023346, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI11545785, Length=168, Percent_Identity=31.547619047619, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI39995082, Length=188, Percent_Identity=29.7872340425532, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI301336155, Length=188, Percent_Identity=29.7872340425532, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI2367212, Length=453, Percent_Identity=31.3465783664459, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI87081985, Length=218, Percent_Identity=32.1100917431193, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17536757, Length=239, Percent_Identity=31.3807531380753, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71998419, Length=241, Percent_Identity=29.8755186721992, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115534021, Length=241, Percent_Identity=29.8755186721992, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324268, Length=312, Percent_Identity=28.525641025641, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319447, Length=198, Percent_Identity=28.2828282828283, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324306, Length=292, Percent_Identity=24.3150684931507, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI22024126, Length=244, Percent_Identity=30.327868852459, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24668781, Length=238, Percent_Identity=31.5126050420168, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21356513, Length=238, Percent_Identity=31.9327731092437, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21355201, Length=189, Percent_Identity=32.2751322751323, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21356579, Length=242, Percent_Identity=26.8595041322314, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19920494, Length=188, Percent_Identity=29.2553191489362, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 49041; Mature: 48910

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKGLVTELVYGTVARKLTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHH
EWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVNEAVELAKLRKKGSEKLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHH
ALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKEEYGEERAKAIFESLLVRNKA
HHHHHHHHCCCCCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAGHNLFADGAITIQDESSQLVAPT
CEEEECCCHHHHHHHHHHCCCCEEEHHHHHHHCCCCCCCCEEECCEEEEECCCCCEEEEE
LDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALDLYDHKLDLIQENAQRLGVEDRVQT
CCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHH
QKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRRKPDIKYNKETADFASLQEIQLEILGS
HHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VCQILGKGGIITYSTCTIVSEENFQVVKAFLESHPEFEQVKLEHECKDIMKDGCILITPE
HHHHHCCCCEEEEEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECH
LYGSDGFFISQFRKISD
HCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKGLVTELVYGTVARKLTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHH
EWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVNEAVELAKLRKKGSEKLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHH
ALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKEEYGEERAKAIFESLLVRNKA
HHHHHHHHCCCCCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAGHNLFADGAITIQDESSQLVAPT
CEEEECCCHHHHHHHHHHCCCCEEEHHHHHHHCCCCCCCCEEECCEEEEECCCCCEEEEE
LDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALDLYDHKLDLIQENAQRLGVEDRVQT
CCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHH
QKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRRKPDIKYNKETADFASLQEIQLEILGS
HHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VCQILGKGGIITYSTCTIVSEENFQVVKAFLESHPEFEQVKLEHECKDIMKDGCILITPE
HHHHHCCCCEEEEEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECH
LYGSDGFFISQFRKISD
HCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]