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The map label for this gene is fmt [H]

Identifier: 221232468

GI number: 221232468

Start: 1678424

End: 1679359

Strand: Reverse

Name: fmt [H]

Synonym: SPN23F_17380

Alternate gene names: 221232468

Gene position: 1679359-1678424 (Counterclockwise)

Preceding gene: 221232469

Following gene: 221232467

Centisome position: 75.6

GC content: 46.37

Gene sequence:

>936_bases
ATGACAAAACTAATCTTTATGGGGACCCCCGACTTTTCAGCAACAGTCTTAAAAGGACTTTTGACAGATGACCGTTACGA
AATTCTAGCCGTTGTGACCCAGCCAGACCGTGCTGTTGGTCGTAAAAAAGTTATCCAAGAAACCCCAGTCAAGCAGGCTG
CCAAGGAAGCAGGACTATCTATCTACCAACCTGAAAAATTATCTGGAAGTCCAGAGATGGAAGAACTTATGAAGCTAGGA
GCAGATGGAATTGTGACTGCTGCTTTTGGGCAGTTTCTCCCAAGCAAACTCCTTGATAGCATGGACTTTGCTGTCAACGT
TCATGCCTCCCTCCTTCCTAGACACCGTGGTGGTGCGCCTATCCATTATGCCTTGATTCAAGGGGATGAGGAAGCTGGTG
TGACCATCATGGAAATGGTTAAGGAAATGGATGCAGGAGATATGATTTCTCGTCGCAGCATTCCGATCACAGATGAGGAC
AATGTTGGCACCTTGTTTGAAAAATTGGCGCTAGTTGGTCGTGATTTGCTTTTGGACACTCTGCCTGCCTATATTGCTGG
TGATATCAAACCTGAACCGCAGGATACGAGTCAGGTTACCTTCTCTCCAAATATAAAGCCAGAGGAAGAAAAACTGGACT
GGAACAAAACCAATCGTCAACTCTTTAACCAAATTCGTGGAATGAACCCCTGGCCTGTTGCCCATGCTTTCCTTAAGGGC
GACCGCTTTAAGATTTATGAAGCCCTACCAGTAGAAGGTCAGGGAAATCCAGGTGAGATTCTCTCTATCGGCAAGAAAGA
ATTGATTGTCGCAACGGCTGAAGGGGCTCTATCCCTCAAACAAGTGCAGCCAGCTGGTAAGCCTAAGATGGACATTGCTT
CCTTCCTCAACGGAGTTGGACGTACATTGACTGTAGGAGAACGATTTGGTGACTAA

Upstream 100 bases:

>100_bases
CCTCAACCAGGTCTTGGCCTTGACTCAAGAACGGGAAAATAGTGAGCTCCGTCTCAGCATTGACCATGAGCCGCAGCAAT
TTTTATAAGAAGGAGAAGAT

Downstream 100 bases:

>100_bases
AGTAGAAACGGCTAGAAGTTTAGCTCTAGCAGTGCTAGAGGATGTTTTTGTGAACCAAGCATACTCAAATATCGCCTTAA
ATAAGCATCTAAAGGGGAGT

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKVIQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLG
ADGIVTAAFGQFLPSKLLDSMDFAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTNRQLFNQIRGMNPWPVAHAFLKG
DRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGALSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD

Sequences:

>Translated_311_residues
MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKVIQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLG
ADGIVTAAFGQFLPSKLLDSMDFAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTNRQLFNQIRGMNPWPVAHAFLKG
DRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGALSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD
>Mature_310_residues
TKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKVIQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGA
DGIVTAAFGQFLPSKLLDSMDFAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDEDN
VGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTNRQLFNQIRGMNPWPVAHAFLKGD
RFKIYEALPVEGQGNPGEILSIGKKELIVATAEGALSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=268, Percent_Identity=25.7462686567164, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI164663775, Length=236, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI21614513, Length=303, Percent_Identity=22.1122112211221, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1789683, Length=310, Percent_Identity=40.9677419354839, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1788589, Length=281, Percent_Identity=30.2491103202847, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI133930964, Length=259, Percent_Identity=30.5019305019305, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319458, Length=285, Percent_Identity=25.6140350877193, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45550868, Length=321, Percent_Identity=26.791277258567, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI28571984, Length=237, Percent_Identity=28.6919831223629, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24585660, Length=241, Percent_Identity=24.4813278008299, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 33972; Mature: 33840

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKVIQETPVKQAAKEAGLS
CCEEEEEECCCHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHCCHHHHHHHCCCE
IYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMDFAVNVHASLLPRHRGGAP
EECCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCCCC
IHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDEDNVGTLFEKLALVGRDLLLDT
EEEEEEECCCCCCCHHHHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTNRQLFNQIRGMNPWPVAHAFLKG
HHHHHCCCCCCCCCCCCEEEECCCCCCCHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHCC
DRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGALSLKQVQPAGKPKMDIASFLNGVG
CCEEEEEEECCCCCCCCCHHEECCCCEEEEEECCCCEEHHHCCCCCCCCHHHHHHHHHCC
RTLTVGERFGD
CEEECCHHCCC
>Mature Secondary Structure 
TKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKVIQETPVKQAAKEAGLS
CEEEEEECCCHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHCCHHHHHHHCCCE
IYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMDFAVNVHASLLPRHRGGAP
EECCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCCCC
IHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDEDNVGTLFEKLALVGRDLLLDT
EEEEEEECCCCCCCHHHHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTNRQLFNQIRGMNPWPVAHAFLKG
HHHHHCCCCCCCCCCCCEEEECCCCCCCHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHCC
DRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGALSLKQVQPAGKPKMDIASFLNGVG
CCEEEEEEECCCCCCCCCHHEECCCCEEEEEECCCCEEHHHCCCCCCCCHHHHHHHHHCC
RTLTVGERFGD
CEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA