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The map label for this gene is rtcB [C]

Identifier: 220933074

GI number: 220933074

Start: 2443423

End: 2444766

Strand: Direct

Name: rtcB [C]

Synonym: Hore_22420

Alternate gene names: 220933074

Gene position: 2443423-2444766 (Clockwise)

Preceding gene: 220933059

Following gene: 220933077

Centisome position: 94.77

GC content: 46.13

Gene sequence:

>1344_bases
TTGAAATACTACCGTTTTAAGCAGGAAGGGAGAATGAACTGTGATGTCCGGGTCTTTGCCACCCGGGACCTCTATAACCA
GATAGAAAAAACAGCCTTAAAACAGCTTTTTAATGCAGCCAGCCTTCCAGGAGTAGTCGGGGTTATAGGACTCCCCGATA
TCCATCAGGGGTATGGATTACCCATCGGTGGAGTAATGTGTTCCAGTTTAAAAAAAGGAGTCATCTCTCCCGGGGCGGTA
GGTTTTGATATAAACTGTGGAGTCCGGCTTTTAGTTGCCGGTTTAAGGCTCGAAGATATAATTGATAAACTGGATGATAT
AATGTCCGGACTGAAAAATGAAATCCCGGCCGGGTTAGGGGTTAATTCAACATTAACATTTACCGACCAGCAATTTGAAC
GGGTAGTTGAGGAGGGACTACCCTTTTTAATAACCAGGCTGGGGTATGGACAGACCATTGATATAGCAGCCTGTGAGGAA
AACGGCCACCTAAAGGGGGCAGATCTTACGGGGGTCTCAAAAAAGGCCATAAACAGGGGTAAAAAACAGCTGGGAACCCT
CGGTTCAGGCAATCATTTTCTTGAAATTCAGGTAATTGATAAGGTCTATAATCATAACTCCGGTCTCGAAGAGGGCCAGA
TCAGTATCATGATCCACACCGGATCCCGGGGTTTTGGCCACCAGATTGCTGAAGATTATATCAACATTGCCAAAAAAAGG
GCCAAAAAATATAATTTTGATTTCCCCACTAAAAACCTGGCCTCCTTCCCCATTAATTCCCCGGAAGGGGAAGACTACTA
CCGGGCCATGGCCTGTGCCGCTAACTTTGCTTTTGCCAACCGGCAGATATTAACCCATTTTGTAAGACAGGTAATAAACC
ACTTTATACCGGGAACCTTTATTACTGTATATTATGACCTCGCCCATAATATCTGCAAAAAGGAAATTCACCAGATAAAT
GGCAAGAAAAAAGCCCTTCTGGTCCACCGTAAAGGGGCTACCAAGCTATCCCCTGACGGCATTGCCCTTGTTCCAGGATC
TATGGGAACAGACAGTTATATTGTCAGGCCGAAAAATCAGGAGGCCCTGAAAGCTGCCTTTGAATCTGTTTCCCATGGAG
CCGGTCGGAAAATGGGGAGAAGGCAGGCCAGAAAGAAACTATCATACCGGGAACATTTAAAGAGTCTGGGGGAAGTCAGA
GTGACCTCGGCCACCAATGACAACCTCCTGGATGAATCACCACTGGCCTATAAGGATATTAGTGAGGTCATAAGGTCCCT
TAAAGAAACCGGGCTGGCAGAACCGGTGGTCCGTCTTAAACCCCTGGCTGTTTTAAAGGGATAG

Upstream 100 bases:

>100_bases
TTCTCAAAAATTTTAAGATAAGATGTCTTTTATAATTTATTTGTATTTATAGACATTTTTCAGAAAAGTTGATATTATAA
GAAAAAGGGAGGGGAATGTT

Downstream 100 bases:

>100_bases
TCTTTTAACGAAGAATGTTAAATACCTTAATGATAATGAAATGATAGGTCTGACCAAGTATATATAGATTCAGTTTAACA
ATAAATGTTATTTTCTAACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKYYRFKQEGRMNCDVRVFATRDLYNQIEKTALKQLFNAASLPGVVGVIGLPDIHQGYGLPIGGVMCSSLKKGVISPGAV
GFDINCGVRLLVAGLRLEDIIDKLDDIMSGLKNEIPAGLGVNSTLTFTDQQFERVVEEGLPFLITRLGYGQTIDIAACEE
NGHLKGADLTGVSKKAINRGKKQLGTLGSGNHFLEIQVIDKVYNHNSGLEEGQISIMIHTGSRGFGHQIAEDYINIAKKR
AKKYNFDFPTKNLASFPINSPEGEDYYRAMACAANFAFANRQILTHFVRQVINHFIPGTFITVYYDLAHNICKKEIHQIN
GKKKALLVHRKGATKLSPDGIALVPGSMGTDSYIVRPKNQEALKAAFESVSHGAGRKMGRRQARKKLSYREHLKSLGEVR
VTSATNDNLLDESPLAYKDISEVIRSLKETGLAEPVVRLKPLAVLKG

Sequences:

>Translated_447_residues
MKYYRFKQEGRMNCDVRVFATRDLYNQIEKTALKQLFNAASLPGVVGVIGLPDIHQGYGLPIGGVMCSSLKKGVISPGAV
GFDINCGVRLLVAGLRLEDIIDKLDDIMSGLKNEIPAGLGVNSTLTFTDQQFERVVEEGLPFLITRLGYGQTIDIAACEE
NGHLKGADLTGVSKKAINRGKKQLGTLGSGNHFLEIQVIDKVYNHNSGLEEGQISIMIHTGSRGFGHQIAEDYINIAKKR
AKKYNFDFPTKNLASFPINSPEGEDYYRAMACAANFAFANRQILTHFVRQVINHFIPGTFITVYYDLAHNICKKEIHQIN
GKKKALLVHRKGATKLSPDGIALVPGSMGTDSYIVRPKNQEALKAAFESVSHGAGRKMGRRQARKKLSYREHLKSLGEVR
VTSATNDNLLDESPLAYKDISEVIRSLKETGLAEPVVRLKPLAVLKG
>Mature_447_residues
MKYYRFKQEGRMNCDVRVFATRDLYNQIEKTALKQLFNAASLPGVVGVIGLPDIHQGYGLPIGGVMCSSLKKGVISPGAV
GFDINCGVRLLVAGLRLEDIIDKLDDIMSGLKNEIPAGLGVNSTLTFTDQQFERVVEEGLPFLITRLGYGQTIDIAACEE
NGHLKGADLTGVSKKAINRGKKQLGTLGSGNHFLEIQVIDKVYNHNSGLEEGQISIMIHTGSRGFGHQIAEDYINIAKKR
AKKYNFDFPTKNLASFPINSPEGEDYYRAMACAANFAFANRQILTHFVRQVINHFIPGTFITVYYDLAHNICKKEIHQIN
GKKKALLVHRKGATKLSPDGIALVPGSMGTDSYIVRPKNQEALKAAFESVSHGAGRKMGRRQARKKLSYREHLKSLGEVR
VTSATNDNLLDESPLAYKDISEVIRSLKETGLAEPVVRLKPLAVLKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=443, Percent_Identity=37.6975169300226, Blast_Score=298, Evalue=5e-81,
Organism=Escherichia coli, GI2367224, Length=429, Percent_Identity=31.2354312354312, Blast_Score=175, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17506665, Length=447, Percent_Identity=37.8076062639821, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24585217, Length=442, Percent_Identity=39.5927601809955, Blast_Score=297, Evalue=9e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 49199; Mature: 49199

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYYRFKQEGRMNCDVRVFATRDLYNQIEKTALKQLFNAASLPGVVGVIGLPDIHQGYGL
CCCCEECCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
PIGGVMCSSLKKGVISPGAVGFDINCGVRLLVAGLRLEDIIDKLDDIMSGLKNEIPAGLG
CHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VNSTLTFTDQQFERVVEEGLPFLITRLGYGQTIDIAACEENGHLKGADLTGVSKKAINRG
CCCEEEECHHHHHHHHHCCCCEEEHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
KKQLGTLGSGNHFLEIQVIDKVYNHNSGLEEGQISIMIHTGSRGFGHQIAEDYINIAKKR
HHHHCCCCCCCEEEEEEEHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
AKKYNFDFPTKNLASFPINSPEGEDYYRAMACAANFAFANRQILTHFVRQVINHFIPGTF
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ITVYYDLAHNICKKEIHQINGKKKALLVHRKGATKLSPDGIALVPGSMGTDSYIVRPKNQ
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCEEECCCCH
EALKAAFESVSHGAGRKMGRRQARKKLSYREHLKSLGEVRVTSATNDNLLDESPLAYKDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHH
SEVIRSLKETGLAEPVVRLKPLAVLKG
HHHHHHHHHCCCCCCHHHHCCHHHCCC
>Mature Secondary Structure
MKYYRFKQEGRMNCDVRVFATRDLYNQIEKTALKQLFNAASLPGVVGVIGLPDIHQGYGL
CCCCEECCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
PIGGVMCSSLKKGVISPGAVGFDINCGVRLLVAGLRLEDIIDKLDDIMSGLKNEIPAGLG
CHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VNSTLTFTDQQFERVVEEGLPFLITRLGYGQTIDIAACEENGHLKGADLTGVSKKAINRG
CCCEEEECHHHHHHHHHCCCCEEEHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
KKQLGTLGSGNHFLEIQVIDKVYNHNSGLEEGQISIMIHTGSRGFGHQIAEDYINIAKKR
HHHHCCCCCCCEEEEEEEHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
AKKYNFDFPTKNLASFPINSPEGEDYYRAMACAANFAFANRQILTHFVRQVINHFIPGTF
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ITVYYDLAHNICKKEIHQINGKKKALLVHRKGATKLSPDGIALVPGSMGTDSYIVRPKNQ
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCEEECCCCH
EALKAAFESVSHGAGRKMGRRQARKKLSYREHLKSLGEVRVTSATNDNLLDESPLAYKDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHH
SEVIRSLKETGLAEPVVRLKPLAVLKG
HHHHHHHHHCCCCCCHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]