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The map label for this gene is manA [H]

Identifier: 220932985

GI number: 220932985

Start: 2343636

End: 2344697

Strand: Direct

Name: manA [H]

Synonym: Hore_21530

Alternate gene names: 220932985

Gene position: 2343636-2344697 (Clockwise)

Preceding gene: 220932974

Following gene: 220933006

Centisome position: 90.9

GC content: 39.08

Gene sequence:

>1062_bases
ATGGAACTGTACCCCCTAAAATTCAAACCAGTTTACAAAAGCAAAATCTGGGGAGGCCGGAAATTAAAAGATGTTTTTAA
CCGGGACCTCCCCGATCAAAACATCGGTGAAAGCTGGGAAGTTGCTGCTCATCCCAACGGAACAAGTATTGTGGCCAATG
GGTCTTTAAAAGGCCAGTCTCTCCCTGACATTATTAATACCTATGGAGACAAGATAACGGGAGAAAAACTGGTAGATATA
TGTCAGGAAAGATTTCCCCTTTTGATTAAATTACTGGATGCTGAAAAAAAACTTTCAGTCCAGGTCCATCCAGACAATGA
TTATGCCCACCGTGTTGAAAATGATTCCGGGAAAACAGAAATGTGGTATATAATTGATGCCAGACCAGGGGCCAGACTCG
TTTATGGACTAAAGCCTGGAACTACAAAAGAACAACTGGCTAAAGCTATAAAAAGAGGTGAAATAGAGAAATATCTTAAC
CGGGTACCAGTAAAAAAGGGAGATGTATTTTTTATGCCTTCAGGAACCATTCATGCCATTGAAGAGGGTATCCTTCTGGC
TGAAATACAACAAAATTCAGATACAACTTACCGTGTCTATGACTGGGACCGGGTTGGACAGGATGGAAACCCACGACCAT
TGCATATTGAAAAAGCCCTTGATGTAATTAATTTTAAAACCGACTCGAGTCTGGTAAATTATAAACCTCTTTCTGTCAAC
ACCGACCAGTACCGCAGGGACTTTTTAGCTGCCTGTCCTTATTTTGTAACAGAATACATTGAGGTCAAGGATGAAATAGA
TTTTATTATAAACAAATTTATAGTATTGATGTGTTTAAAGGGTACTGGTGAAATCCACTATAATAACCGGAAAACCAGAA
TAGCTGCCGGTGAAACCCTTTTAATTCCGGCTGCTTTAGAAAAAATAAAGATCAGAGGGAATGTAAACTTTATCAAAACA
TTCATACCTTCCAGTAAATCTAATGTTATTAATGAACTGGCCGAACTGGGGTTTGACGAAGATAAAATAAAAACAATCCC
GGGATTAACCAGCTGGAAATAA

Upstream 100 bases:

>100_bases
TTTAATTAGAGGGTTTATAGTCCTTTTTATAGAAATAACATTTTGGTCAGACAAGATTTATTCAGATAAAATAATAATAA
ATACAGTGAGGTGAATAAAA

Downstream 100 bases:

>100_bases
CTGGAATCAAATTAATAAAATTTTTTTGTATATAATCTGAATTCCTGGTTATAATACTAAATGCAAGGTCAACAGTGGTT
GAGCGCAGATCGGTCCGGGC

Product: mannose-6-phosphate isomerase, class I

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MELYPLKFKPVYKSKIWGGRKLKDVFNRDLPDQNIGESWEVAAHPNGTSIVANGSLKGQSLPDIINTYGDKITGEKLVDI
CQERFPLLIKLLDAEKKLSVQVHPDNDYAHRVENDSGKTEMWYIIDARPGARLVYGLKPGTTKEQLAKAIKRGEIEKYLN
RVPVKKGDVFFMPSGTIHAIEEGILLAEIQQNSDTTYRVYDWDRVGQDGNPRPLHIEKALDVINFKTDSSLVNYKPLSVN
TDQYRRDFLAACPYFVTEYIEVKDEIDFIINKFIVLMCLKGTGEIHYNNRKTRIAAGETLLIPAALEKIKIRGNVNFIKT
FIPSSKSNVINELAELGFDEDKIKTIPGLTSWK

Sequences:

>Translated_353_residues
MELYPLKFKPVYKSKIWGGRKLKDVFNRDLPDQNIGESWEVAAHPNGTSIVANGSLKGQSLPDIINTYGDKITGEKLVDI
CQERFPLLIKLLDAEKKLSVQVHPDNDYAHRVENDSGKTEMWYIIDARPGARLVYGLKPGTTKEQLAKAIKRGEIEKYLN
RVPVKKGDVFFMPSGTIHAIEEGILLAEIQQNSDTTYRVYDWDRVGQDGNPRPLHIEKALDVINFKTDSSLVNYKPLSVN
TDQYRRDFLAACPYFVTEYIEVKDEIDFIINKFIVLMCLKGTGEIHYNNRKTRIAAGETLLIPAALEKIKIRGNVNFIKT
FIPSSKSNVINELAELGFDEDKIKTIPGLTSWK
>Mature_353_residues
MELYPLKFKPVYKSKIWGGRKLKDVFNRDLPDQNIGESWEVAAHPNGTSIVANGSLKGQSLPDIINTYGDKITGEKLVDI
CQERFPLLIKLLDAEKKLSVQVHPDNDYAHRVENDSGKTEMWYIIDARPGARLVYGLKPGTTKEQLAKAIKRGEIEKYLN
RVPVKKGDVFFMPSGTIHAIEEGILLAEIQQNSDTTYRVYDWDRVGQDGNPRPLHIEKALDVINFKTDSSLVNYKPLSVN
TDQYRRDFLAACPYFVTEYIEVKDEIDFIINKFIVLMCLKGTGEIHYNNRKTRIAAGETLLIPAALEKIKIRGNVNFIKT
FIPSSKSNVINELAELGFDEDKIKTIPGLTSWK

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 40061; Mature: 40061

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELYPLKFKPVYKSKIWGGRKLKDVFNRDLPDQNIGESWEVAAHPNGTSIVANGSLKGQS
CCCCCCCCCCCHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCC
LPDIINTYGDKITGEKLVDICQERFPLLIKLLDAEKKLSVQVHPDNDYAHRVENDSGKTE
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCCEE
MWYIIDARPGARLVYGLKPGTTKEQLAKAIKRGEIEKYLNRVPVKKGDVFFMPSGTIHAI
EEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCHHHHHHHHCCCCCCCEEEECCCCHHHH
EEGILLAEIQQNSDTTYRVYDWDRVGQDGNPRPLHIEKALDVINFKTDSSLVNYKPLSVN
HCCEEEEEEECCCCCEEEEEEHHHCCCCCCCCCEEHHHHHHHHEECCCCCEEEEECCCCC
TDQYRRDFLAACPYFVTEYIEVKDEIDFIINKFIVLMCLKGTGEIHYNNRKTRIAAGETL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCEEEEECCCEE
LIPAALEKIKIRGNVNFIKTFIPSSKSNVINELAELGFDEDKIKTIPGLTSWK
EEECHHEEEEEECCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MELYPLKFKPVYKSKIWGGRKLKDVFNRDLPDQNIGESWEVAAHPNGTSIVANGSLKGQS
CCCCCCCCCCCHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCC
LPDIINTYGDKITGEKLVDICQERFPLLIKLLDAEKKLSVQVHPDNDYAHRVENDSGKTE
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCCEE
MWYIIDARPGARLVYGLKPGTTKEQLAKAIKRGEIEKYLNRVPVKKGDVFFMPSGTIHAI
EEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCHHHHHHHHCCCCCCCEEEECCCCHHHH
EEGILLAEIQQNSDTTYRVYDWDRVGQDGNPRPLHIEKALDVINFKTDSSLVNYKPLSVN
HCCEEEEEEECCCCCEEEEEEHHHCCCCCCCCCEEHHHHHHHHEECCCCCEEEEECCCCC
TDQYRRDFLAACPYFVTEYIEVKDEIDFIINKFIVLMCLKGTGEIHYNNRKTRIAAGETL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCEEEEECCCEE
LIPAALEKIKIRGNVNFIKTFIPSSKSNVINELAELGFDEDKIKTIPGLTSWK
EEECHHEEEEEECCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]