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The map label for this gene is ilvH [H]

Identifier: 220931925

GI number: 220931925

Start: 1178226

End: 1178732

Strand: Direct

Name: ilvH [H]

Synonym: Hore_10840

Alternate gene names: 220931925

Gene position: 1178226-1178732 (Clockwise)

Preceding gene: 220931924

Following gene: 220931926

Centisome position: 45.7

GC content: 38.66

Gene sequence:

>507_bases
ATGACTCATATACTTTCGGTATCTGTTTTAAATAAGCCGGGTGTTTTAACCAGAATCGCCAGCCTTTTTAGCCGGAGGAA
TTTTAATATTGAAAGCCTGAATGTGGGCCATACAGAAAATCCGGAAATATCCAGGATGACAATTGTTGTCAAGGGGGATG
ACAGGGTTCTGGAGCAGGTGAAAAAACAGCTCCATAAATTAATAGATGTTATTAAAATTACAGAATTAAATCAGGATTCA
CTGGTCAGTAGGGACCTGGCTTTAATAAGGGTAAACTGTCCCCGGAAACAGAGAACAGAAGTTATTCAGATTGCTGATAC
TTTCAGGGCCAAGATTGTTGATGTGGCTTATGATAGTATGATGATTGAAACTACAGGAACTGAAGACAAAATTGAGGCTT
TAATTGAAGTCTTAAAGGATTTTGGAATAATTGAGGTAGTCAGAACCGGTTTAGTTGCTTTAAGCCGGGGGCTTGACCTC
CAGGGTAAAAATCAGAAAATAAGTTAA

Upstream 100 bases:

>100_bases
GCCCTGCTTTACTGGATGTCAGAATTGAGGAAGAAGAAAATGTATTTCCCATGGTACCACAGGGAGCAGGAATTAAAAAA
ATGATAGGAGGTTAACAGTT

Downstream 100 bases:

>100_bases
AGGAGTGGTTATTGTTATGATTCATGTCTATTATGATAAAGACGCCAACCTGGGATTACTTGAGGAAAAGATGATTGCTG
TACTGGGTTATGGGAGCCAG

Product: acetolactate synthase, small subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MTHILSVSVLNKPGVLTRIASLFSRRNFNIESLNVGHTENPEISRMTIVVKGDDRVLEQVKKQLHKLIDVIKITELNQDS
LVSRDLALIRVNCPRKQRTEVIQIADTFRAKIVDVAYDSMMIETTGTEDKIEALIEVLKDFGIIEVVRTGLVALSRGLDL
QGKNQKIS

Sequences:

>Translated_168_residues
MTHILSVSVLNKPGVLTRIASLFSRRNFNIESLNVGHTENPEISRMTIVVKGDDRVLEQVKKQLHKLIDVIKITELNQDS
LVSRDLALIRVNCPRKQRTEVIQIADTFRAKIVDVAYDSMMIETTGTEDKIEALIEVLKDFGIIEVVRTGLVALSRGLDL
QGKNQKIS
>Mature_167_residues
THILSVSVLNKPGVLTRIASLFSRRNFNIESLNVGHTENPEISRMTIVVKGDDRVLEQVKKQLHKLIDVIKITELNQDSL
VSRDLALIRVNCPRKQRTEVIQIADTFRAKIVDVAYDSMMIETTGTEDKIEALIEVLKDFGIIEVVRTGLVALSRGLDLQ
GKNQKIS

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=158, Percent_Identity=43.6708860759494, Blast_Score=140, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6319837, Length=203, Percent_Identity=25.615763546798, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18891; Mature: 18760

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHILSVSVLNKPGVLTRIASLFSRRNFNIESLNVGHTENPEISRMTIVVKGDDRVLEQV
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEEEECCHHHHHHH
KKQLHKLIDVIKITELNQDSLVSRDLALIRVNCPRKQRTEVIQIADTFRAKIVDVAYDSM
HHHHHHHHHHHHHHCCCHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCE
MIETTGTEDKIEALIEVLKDFGIIEVVRTGLVALSRGLDLQGKNQKIS
EEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
THILSVSVLNKPGVLTRIASLFSRRNFNIESLNVGHTENPEISRMTIVVKGDDRVLEQV
CEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEEEECCHHHHHHH
KKQLHKLIDVIKITELNQDSLVSRDLALIRVNCPRKQRTEVIQIADTFRAKIVDVAYDSM
HHHHHHHHHHHHHHCCCHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCE
MIETTGTEDKIEALIEVLKDFGIIEVVRTGLVALSRGLDLQGKNQKIS
EEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]