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The map label for this gene is lytT [H]

Identifier: 220931885

GI number: 220931885

Start: 1130371

End: 1131132

Strand: Direct

Name: lytT [H]

Synonym: Hore_10420

Alternate gene names: 220931885

Gene position: 1130371-1131132 (Clockwise)

Preceding gene: 220931884

Following gene: 220931886

Centisome position: 43.84

GC content: 34.78

Gene sequence:

>762_bases
ATGGAAATGCAGGCTTTAGTAGTTGACGATGAAGCACCGGCCAGAAATGAGTTAATATTTATGCTTGAAAATAGTAAGGT
TAATTTCCGGGTCAGGGAGGCAGATAATGGGAAAAAAGCCCTTGAGCTTGTAAATAATCATAATTTTGATGTGATTTTCC
TGGATATTCAGATGCCTTCTTTAACCGGACTGGAAGTAGCTGCTGAAATTCTTAAGGTGGAGGATAAACCTGAAATTGTT
TTTGTTACAGCTTATGATGAATATGCTATTAAGGCTTTTGAATTAAATGCTGTTGATTATTTACTGAAGCCATTTTCCAG
GAAGCGTTTTGAGGAAACCATTAACCGGGTAATGAGTCATTCAAAAAAAGATAGAATAAAAGATACTATAAAAATAAATA
AGGCTATTTCCCAATTAACCCCGGAATTAAAAAGGATACCGGTAAATTCAAAACGGGGACGGATTAAGTTATTAAAACCT
TCAGAGATTTACTATGCCACAACTGAAGGGGGTAAGGTCTTTATAACATCTGAAGAGGGTGTATTTGAGTTTGCTAATGG
ATTAAAGGAGCTTGAAGAAATGTTAAACCTGCCCCAATTTTTTAGATGCCATCGAAGTTACCTTGTTAATCTGTCTAAAG
TAAAAGAACTGATTCCCTGGTTTAAAGGAAATTATTATCTTATTATTAATGATGAAAGTGAAGAGGAAATTCCGGTAGGG
AGAACCAGGGTGAACGAGTTAAAGAAAAAATTAAATTTATAG

Upstream 100 bases:

>100_bases
GTCCAGAGTATGGACTTACCATGGAGAGTGAAGAAAATACGGGGACCGAAGTTGTAATAAAAGTACCGTTACAGACAATT
AAAAGAGAGGAGAACACCCC

Downstream 100 bases:

>100_bases
TTAAATTAATAGTATTTAAAATATATATTTTTATTTAAAATATATATTTTACAGTTTGTCCCCCTATTTTTACAATTTAG
AGAAATTATATAGGTAATAT

Product: two component transcriptional regulator, LytTR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MEMQALVVDDEAPARNELIFMLENSKVNFRVREADNGKKALELVNNHNFDVIFLDIQMPSLTGLEVAAEILKVEDKPEIV
FVTAYDEYAIKAFELNAVDYLLKPFSRKRFEETINRVMSHSKKDRIKDTIKINKAISQLTPELKRIPVNSKRGRIKLLKP
SEIYYATTEGGKVFITSEEGVFEFANGLKELEEMLNLPQFFRCHRSYLVNLSKVKELIPWFKGNYYLIINDESEEEIPVG
RTRVNELKKKLNL

Sequences:

>Translated_253_residues
MEMQALVVDDEAPARNELIFMLENSKVNFRVREADNGKKALELVNNHNFDVIFLDIQMPSLTGLEVAAEILKVEDKPEIV
FVTAYDEYAIKAFELNAVDYLLKPFSRKRFEETINRVMSHSKKDRIKDTIKINKAISQLTPELKRIPVNSKRGRIKLLKP
SEIYYATTEGGKVFITSEEGVFEFANGLKELEEMLNLPQFFRCHRSYLVNLSKVKELIPWFKGNYYLIINDESEEEIPVG
RTRVNELKKKLNL
>Mature_253_residues
MEMQALVVDDEAPARNELIFMLENSKVNFRVREADNGKKALELVNNHNFDVIFLDIQMPSLTGLEVAAEILKVEDKPEIV
FVTAYDEYAIKAFELNAVDYLLKPFSRKRFEETINRVMSHSKKDRIKDTIKINKAISQLTPELKRIPVNSKRGRIKLLKP
SEIYYATTEGGKVFITSEEGVFEFANGLKELEEMLNLPQFFRCHRSYLVNLSKVKELIPWFKGNYYLIINDESEEEIPVG
RTRVNELKKKLNL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=252, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI87082052, Length=253, Percent_Identity=37.5494071146245, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1788550, Length=183, Percent_Identity=27.8688524590164, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=30.5084745762712, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 29363; Mature: 29363

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMQALVVDDEAPARNELIFMLENSKVNFRVREADNGKKALELVNNHNFDVIFLDIQMPS
CCCEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHCCCCEEEEEEEEECCC
LTGLEVAAEILKVEDKPEIVFVTAYDEYAIKAFELNAVDYLLKPFSRKRFEETINRVMSH
CCHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHC
SKKDRIKDTIKINKAISQLTPELKRIPVNSKRGRIKLLKPSEIYYATTEGGKVFITSEEG
CHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEEEECCCEEEEEECCCCEEEEECCCC
VFEFANGLKELEEMLNLPQFFRCHRSYLVNLSKVKELIPWFKGNYYLIINDESEEEIPVG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
RTRVNELKKKLNL
HHHHHHHHHHHCC
>Mature Secondary Structure
MEMQALVVDDEAPARNELIFMLENSKVNFRVREADNGKKALELVNNHNFDVIFLDIQMPS
CCCEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHCCCCEEEEEEEEECCC
LTGLEVAAEILKVEDKPEIVFVTAYDEYAIKAFELNAVDYLLKPFSRKRFEETINRVMSH
CCHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHC
SKKDRIKDTIKINKAISQLTPELKRIPVNSKRGRIKLLKPSEIYYATTEGGKVFITSEEG
CHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEEEECCCEEEEEECCCCEEEEECCCC
VFEFANGLKELEEMLNLPQFFRCHRSYLVNLSKVKELIPWFKGNYYLIINDESEEEIPVG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
RTRVNELKKKLNL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]