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The map label for this gene is glcD [H]

Identifier: 221230899

GI number: 221230899

Start: 3147564

End: 3148913

Strand: Reverse

Name: glcD [H]

Synonym: MLBr_02631

Alternate gene names: 221230899

Gene position: 3148913-3147564 (Counterclockwise)

Preceding gene: 221230900

Following gene: 221230898

Centisome position: 96.35

GC content: 62.37

Gene sequence:

>1350_bases
ATGCTGCGCAGCCTTGCGGCCGTGGTGGGATCGAGCCACGTAATTGCGGATCCCGATGTACTGATCGCCCACAGCATTGA
TCACACAGGTCGGTATCGGGGCCAGGCCAGGGCGTTGGTGAGGCCGGGTACGGCCGAGCAGGTGACTGAGGTACTGCGGG
TCTGCCGCGATGTCGGGGCACACGTCACCGTTCAAGGCGGTCGGACCTCATTGGTGGCCGGTACCGTCCCGGAGCACAAT
GACGTGCTGTTGTCCACCGAGCGGCTACGGTCCATCAGTGAGGTAGACACCGTCGAGCGCCGTCTCCGGGTCGGTGCCGG
AGCAACCTTGACTGCGGTGCAAAATGCCGCTACCGCAGCCGGTTTGGTGTTCGGCGTGGACCTGTGCGCCCGCGCCACCG
CGACCGTAGGCGGAATGGCCTCAACGAACGCCGGCGGCCTACGCACCGTTCGCTACGGCAACATGGGCGAGCAAGTCATC
GGCCTAGAGGTGGCACTGCCCGACGGTTCGCTGCTGTGTAGGCACAGTCTGGCGCGCTTCGACAACACCGGCTATAACTT
GCCGGCCCTGTTTGTCGGCGCCGAAGGCACCCTCGGTGTCATCACTGCGTTGGATCTGCGACTCCACCCGGCCCCGGCGC
ACCGGGTGACGGCGGTCTGCGGGTTCTCCGACCTCGGTGCGCTGGTCGATGCCAGCCGGGCTTTTAGGGACGTGTATGGG
ATTGCTGCACTGGAATTGATCGACGGCCGTGCCAGTTCGCTGATCCGCGAGCACCTAGGGGTGAGCTCCCCGGTTGATGG
CGACTGGCTGTTACTGGTGGAACTGGCCGCTGACCACGACCAGACCAATCGACTCGCTGAACTGTCCATGGCCGTGCAGA
TGTGTGGCGTTCCCGCGGTGGGTGTGGATGCCGGGGCACAGCAGCGGTTATGGCGCGTGCGCGAATCGTTGGCGGAGGTG
CTCGGCGTTTATGGGCCGCCGCTGAAATTTGACGTTTCGTTGCCTCTATCGGCGATTAGTGGATTCGCAAAGGAAGCAGC
AACTTTGATCGACGCGCAAGTATCGGATGTTCAGGAAGCGCTGCCCGTGCTGTTCGGTCACGTCGGTGAGGGCAATCTGC
ACCTCAACGTTTTACGCTGTCCACCCGATCGCGAGAAGACGTTGACCGCAGCGATGATGGAACTCATAGCGCAAGCCGGC
GGCAATGTAAGCTCGGAACACGGCGTAGGTAGTAACAAGCGTGCCTATCTTAGGATGTCGCGGGATCCGGCCGATATCGC
TGCTATGCGGACGATCAAAGCGGCGTTGGATCCTACCGGCTACCTCAATGCTGCGGTTTTGTTCGATTAA

Upstream 100 bases:

>100_bases
GAACATTTGTGAAACTTAGTGAACGCCTATAGAGATCCCTCCACAGGATTGCCGGTCGACCTGCACGACGCAGCGGTCCG
CGGGTGATATAACCGCAAAC

Downstream 100 bases:

>100_bases
TCGGTCCGGAGCCGCTTGATTCTAACCACAGGGCGCAGCGCCGCTAGAAATGAATCCGTGTAGTCGCTTCGGACCACGTA
GTATGGTGCCTCGATCCGGA

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MLRSLAAVVGSSHVIADPDVLIAHSIDHTGRYRGQARALVRPGTAEQVTEVLRVCRDVGAHVTVQGGRTSLVAGTVPEHN
DVLLSTERLRSISEVDTVERRLRVGAGATLTAVQNAATAAGLVFGVDLCARATATVGGMASTNAGGLRTVRYGNMGEQVI
GLEVALPDGSLLCRHSLARFDNTGYNLPALFVGAEGTLGVITALDLRLHPAPAHRVTAVCGFSDLGALVDASRAFRDVYG
IAALELIDGRASSLIREHLGVSSPVDGDWLLLVELAADHDQTNRLAELSMAVQMCGVPAVGVDAGAQQRLWRVRESLAEV
LGVYGPPLKFDVSLPLSAISGFAKEAATLIDAQVSDVQEALPVLFGHVGEGNLHLNVLRCPPDREKTLTAAMMELIAQAG
GNVSSEHGVGSNKRAYLRMSRDPADIAAMRTIKAALDPTGYLNAAVLFD

Sequences:

>Translated_449_residues
MLRSLAAVVGSSHVIADPDVLIAHSIDHTGRYRGQARALVRPGTAEQVTEVLRVCRDVGAHVTVQGGRTSLVAGTVPEHN
DVLLSTERLRSISEVDTVERRLRVGAGATLTAVQNAATAAGLVFGVDLCARATATVGGMASTNAGGLRTVRYGNMGEQVI
GLEVALPDGSLLCRHSLARFDNTGYNLPALFVGAEGTLGVITALDLRLHPAPAHRVTAVCGFSDLGALVDASRAFRDVYG
IAALELIDGRASSLIREHLGVSSPVDGDWLLLVELAADHDQTNRLAELSMAVQMCGVPAVGVDAGAQQRLWRVRESLAEV
LGVYGPPLKFDVSLPLSAISGFAKEAATLIDAQVSDVQEALPVLFGHVGEGNLHLNVLRCPPDREKTLTAAMMELIAQAG
GNVSSEHGVGSNKRAYLRMSRDPADIAAMRTIKAALDPTGYLNAAVLFD
>Mature_449_residues
MLRSLAAVVGSSHVIADPDVLIAHSIDHTGRYRGQARALVRPGTAEQVTEVLRVCRDVGAHVTVQGGRTSLVAGTVPEHN
DVLLSTERLRSISEVDTVERRLRVGAGATLTAVQNAATAAGLVFGVDLCARATATVGGMASTNAGGLRTVRYGNMGEQVI
GLEVALPDGSLLCRHSLARFDNTGYNLPALFVGAEGTLGVITALDLRLHPAPAHRVTAVCGFSDLGALVDASRAFRDVYG
IAALELIDGRASSLIREHLGVSSPVDGDWLLLVELAADHDQTNRLAELSMAVQMCGVPAVGVDAGAQQRLWRVRESLAEV
LGVYGPPLKFDVSLPLSAISGFAKEAATLIDAQVSDVQEALPVLFGHVGEGNLHLNVLRCPPDREKTLTAAMMELIAQAG
GNVSSEHGVGSNKRAYLRMSRDPADIAAMRTIKAALDPTGYLNAAVLFD

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=441, Percent_Identity=33.5600907029478, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI37595756, Length=465, Percent_Identity=32.258064516129, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI37595754, Length=486, Percent_Identity=31.2757201646091, Blast_Score=155, Evalue=5e-38,
Organism=Escherichia coli, GI1789351, Length=437, Percent_Identity=28.8329519450801, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI48994907, Length=486, Percent_Identity=21.6049382716049, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534361, Length=444, Percent_Identity=29.5045045045045, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71992373, Length=470, Percent_Identity=29.3617021276596, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71992381, Length=473, Percent_Identity=29.3868921775898, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71992392, Length=368, Percent_Identity=31.25, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320023, Length=470, Percent_Identity=32.9787234042553, Blast_Score=246, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6320764, Length=446, Percent_Identity=30.0448430493274, Blast_Score=210, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6320027, Length=437, Percent_Identity=28.8329519450801, Blast_Score=149, Evalue=8e-37,
Organism=Drosophila melanogaster, GI18921117, Length=456, Percent_Identity=33.1140350877193, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24639277, Length=456, Percent_Identity=33.1140350877193, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24639275, Length=456, Percent_Identity=33.1140350877193, Blast_Score=216, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 47158; Mature: 47158

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSLAAVVGSSHVIADPDVLIAHSIDHTGRYRGQARALVRPGTAEQVTEVLRVCRDVGA
CCHHHHHHHCCCCEEECCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
HVTVQGGRTSLVAGTVPEHNDVLLSTERLRSISEVDTVERRLRVGAGATLTAVQNAATAA
EEEEECCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GLVFGVDLCARATATVGGMASTNAGGLRTVRYGNMGEQVIGLEVALPDGSLLCRHSLARF
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHH
DNTGYNLPALFVGAEGTLGVITALDLRLHPAPAHRVTAVCGFSDLGALVDASRAFRDVYG
CCCCCCCCEEEECCCCCEEEEEEEEEEECCCCCHHHEEEECCHHHHHHHHHHHHHHHHHH
IAALELIDGRASSLIREHLGVSSPVDGDWLLLVELAADHDQTNRLAELSMAVQMCGVPAV
HHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCC
GVDAGAQQRLWRVRESLAEVLGVYGPPLKFDVSLPLSAISGFAKEAATLIDAQVSDVQEA
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LPVLFGHVGEGNLHLNVLRCPPDREKTLTAAMMELIAQAGGNVSSEHGVGSNKRAYLRMS
HHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
RDPADIAAMRTIKAALDPTGYLNAAVLFD
CCCHHHHHHHHHHHHCCCCCCCCEEEEEC
>Mature Secondary Structure
MLRSLAAVVGSSHVIADPDVLIAHSIDHTGRYRGQARALVRPGTAEQVTEVLRVCRDVGA
CCHHHHHHHCCCCEEECCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
HVTVQGGRTSLVAGTVPEHNDVLLSTERLRSISEVDTVERRLRVGAGATLTAVQNAATAA
EEEEECCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GLVFGVDLCARATATVGGMASTNAGGLRTVRYGNMGEQVIGLEVALPDGSLLCRHSLARF
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHH
DNTGYNLPALFVGAEGTLGVITALDLRLHPAPAHRVTAVCGFSDLGALVDASRAFRDVYG
CCCCCCCCEEEECCCCCEEEEEEEEEEECCCCCHHHEEEECCHHHHHHHHHHHHHHHHHH
IAALELIDGRASSLIREHLGVSSPVDGDWLLLVELAADHDQTNRLAELSMAVQMCGVPAV
HHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCC
GVDAGAQQRLWRVRESLAEVLGVYGPPLKFDVSLPLSAISGFAKEAATLIDAQVSDVQEA
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LPVLFGHVGEGNLHLNVLRCPPDREKTLTAAMMELIAQAGGNVSSEHGVGSNKRAYLRMS
HHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
RDPADIAAMRTIKAALDPTGYLNAAVLFD
CCCHHHHHHHHHHHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]