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The map label for this gene is senX3 [H]

Identifier: 221230795

GI number: 221230795

Start: 2915026

End: 2916351

Strand: Reverse

Name: senX3 [H]

Synonym: MLBr_02440

Alternate gene names: 221230795

Gene position: 2916351-2915026 (Counterclockwise)

Preceding gene: 221230796

Following gene: 221230794

Centisome position: 89.24

GC content: 60.33

Gene sequence:

>1326_bases
GTGTTCTCGGCTCTGTTGTTGGCCGGGGTATTGTCCGGGTTGGCGTTTGTTGTTGGTATTGTGGCAGGAATCCGGCTGTC
GCCGCGACTAATCGAACGCCGGCAAAGACTGGCTAACGAATGGGCGGGCATCACTGTTTTGCAGATGCTGCAACGCATCA
TCGCGTTGATGCCGCTAGGTGCTGCGGTGGTTGATACCTATCGTGATGTAGTTTACCTCAACGAACAGGCCAAGGAGCTA
GGACTCGTGCGCGACCGGCAGCTCGATGACCAGGCCTGGCGGGCAGCACAGCAGGCGCTGGGCGGTGACGATGTCGAATT
TGACCTGTTGCCCGGAAAACGCCCGGCTGCGGGCCGGTCTGGGTTATCGGTGCACGGCCACGCTCGACTGCTAAGTGAGA
AAGACCGCCGGTTCGCCGTGGTCTTCGTCCACGACCAGTCCGACTATGTGCGCATGGAGGCGGCTAGGCGTGACTTCGTA
GCCAATGTTAGCCACGAGCTCAAGACCCCGGTCGGCGCCATGGCCTTGCTAGCTGAGGCTCTGCTGGCATCGGCGGATGA
CGCCGAAACCGTGAGCCGGTTCGCCGAGAAGGTGCTCATCGAGGCCAATCGATTAGGATACATGGTTGCTGAGCTCATAG
AGTTGTCCCGGCTGCAGGGCGCCGAGCGGCTGCCTAACGTAACGGACATTGACGTCGATATCATCGTGTCCGAGGCGATT
GCGCGCCATAAGGTGGCCGCCGACACCGCTGCTATCGAGGTTCGCACCGATCCGCCTAGCGGTTTGCGGGTATTGGGCGA
CCAAACTCTACTGGTTACCGCGCTAGCCAATCTGGTGTCCAACGCGATTGCCTACTCGCCGGGTGGTTCGCTGGTGTCGA
TCAGCCGTCGCCGTCGTGGCGACAATATCGAGATCGCCGTCACCGACCGCGGCATTGGCATCGCTCTTGAAGATCAGGAG
CGGGTCTTCGAACGCTTCTTCCGCGGAGACAAGGCGCGCTCGCGGGCTACCGGTGGCAGCGGGCTGGGGCTGGCCATCGT
CAAACACGTTGCCGCCAACCACAATGGCAGTATCGGTGTGTGGAGCAAGCCGGGAACCGGATCTACGTTCACCCTGTCTA
TTCCGGCGGCCATGCCGCTTTACCAGGACAACGATGAGCAATCCGGGCAACCCCGGGGCTGCGATATGTGGCTCAATAGG
CCGCAACGAGAGGAAGAAGAGTTTAAGTCGATGACACCCGCGCAGGCGATGATGCAGAGCGAAGTGACGAGAGGGAATGT
GAATGATAAGTGTCCTGATTGTGGAGGACGAGGAATCGCTGGCTGA

Upstream 100 bases:

>100_bases
ACAGCTGAACACCTGTAACGCAAAGTGTGACTTTTCCGATTTTGGTCTCGCACCGCTGGGGCGGCGTTAATGAAGGATTT
GTAAGATTTTTTATGTGACT

Downstream 100 bases:

>100_bases
TCCACTGGCGTTTCTCCTCCGCAAGGAGGTTTTGAGCCCACGGTGGTGACCGATGGGCCAGCGGCACTAGCGGAGTTCGA
TCGCTCCGGGGCGGACATCG

Product: putative two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MFSALLLAGVLSGLAFVVGIVAGIRLSPRLIERRQRLANEWAGITVLQMLQRIIALMPLGAAVVDTYRDVVYLNEQAKEL
GLVRDRQLDDQAWRAAQQALGGDDVEFDLLPGKRPAAGRSGLSVHGHARLLSEKDRRFAVVFVHDQSDYVRMEAARRDFV
ANVSHELKTPVGAMALLAEALLASADDAETVSRFAEKVLIEANRLGYMVAELIELSRLQGAERLPNVTDIDVDIIVSEAI
ARHKVAADTAAIEVRTDPPSGLRVLGDQTLLVTALANLVSNAIAYSPGGSLVSISRRRRGDNIEIAVTDRGIGIALEDQE
RVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGSIGVWSKPGTGSTFTLSIPAAMPLYQDNDEQSGQPRGCDMWLNR
PQREEEEFKSMTPAQAMMQSEVTRGNVNDKCPDCGGRGIAG

Sequences:

>Translated_441_residues
MFSALLLAGVLSGLAFVVGIVAGIRLSPRLIERRQRLANEWAGITVLQMLQRIIALMPLGAAVVDTYRDVVYLNEQAKEL
GLVRDRQLDDQAWRAAQQALGGDDVEFDLLPGKRPAAGRSGLSVHGHARLLSEKDRRFAVVFVHDQSDYVRMEAARRDFV
ANVSHELKTPVGAMALLAEALLASADDAETVSRFAEKVLIEANRLGYMVAELIELSRLQGAERLPNVTDIDVDIIVSEAI
ARHKVAADTAAIEVRTDPPSGLRVLGDQTLLVTALANLVSNAIAYSPGGSLVSISRRRRGDNIEIAVTDRGIGIALEDQE
RVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGSIGVWSKPGTGSTFTLSIPAAMPLYQDNDEQSGQPRGCDMWLNR
PQREEEEFKSMTPAQAMMQSEVTRGNVNDKCPDCGGRGIAG
>Mature_441_residues
MFSALLLAGVLSGLAFVVGIVAGIRLSPRLIERRQRLANEWAGITVLQMLQRIIALMPLGAAVVDTYRDVVYLNEQAKEL
GLVRDRQLDDQAWRAAQQALGGDDVEFDLLPGKRPAAGRSGLSVHGHARLLSEKDRRFAVVFVHDQSDYVRMEAARRDFV
ANVSHELKTPVGAMALLAEALLASADDAETVSRFAEKVLIEANRLGYMVAELIELSRLQGAERLPNVTDIDVDIIVSEAI
ARHKVAADTAAIEVRTDPPSGLRVLGDQTLLVTALANLVSNAIAYSPGGSLVSISRRRRGDNIEIAVTDRGIGIALEDQE
RVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGSIGVWSKPGTGSTFTLSIPAAMPLYQDNDEQSGQPRGCDMWLNR
PQREEEEFKSMTPAQAMMQSEVTRGNVNDKCPDCGGRGIAG

Specific function: Probably forms part of a two-component regulatory system senX3/regX3. Phosphorylates regX3 (Probable) [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=255, Percent_Identity=33.3333333333333, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=30.9012875536481, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786783, Length=219, Percent_Identity=28.7671232876712, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=30.672268907563, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=27.5109170305677, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693157, Length=385, Percent_Identity=25.974025974026, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=243, Percent_Identity=25.1028806584362, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=28.9592760180996, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=26.6094420600858, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787894, Length=240, Percent_Identity=27.5, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=30.9178743961353, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=28.3898305084746, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=25.8928571428571, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789403, Length=208, Percent_Identity=30.2884615384615, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789808, Length=246, Percent_Identity=28.8617886178862, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788279, Length=234, Percent_Identity=27.3504273504274, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=217, Percent_Identity=30.4147465437788, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081816, Length=233, Percent_Identity=27.0386266094421, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47767; Mature: 47767

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSALLLAGVLSGLAFVVGIVAGIRLSPRLIERRQRLANEWAGITVLQMLQRIIALMPLG
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
AAVVDTYRDVVYLNEQAKELGLVRDRQLDDQAWRAAQQALGGDDVEFDLLPGKRPAAGRS
HHHHHHHHHHEEECHHHHHHCCHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCC
GLSVHGHARLLSEKDRRFAVVFVHDQSDYVRMEAARRDFVANVSHELKTPVGAMALLAEA
CCEECHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LLASADDAETVSRFAEKVLIEANRLGYMVAELIELSRLQGAERLPNVTDIDVDIIVSEAI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHH
ARHKVAADTAAIEVRTDPPSGLRVLGDQTLLVTALANLVSNAIAYSPGGSLVSISRRRRG
HHHHHHCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHEECCCCCEEEEHHHCCC
DNIEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGSIGV
CCEEEEEECCCCEEEECCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCEEE
WSKPGTGSTFTLSIPAAMPLYQDNDEQSGQPRGCDMWLNRPQREEEEFKSMTPAQAMMQS
ECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHCCCHHHHHHHH
EVTRGNVNDKCPDCGGRGIAG
HHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFSALLLAGVLSGLAFVVGIVAGIRLSPRLIERRQRLANEWAGITVLQMLQRIIALMPLG
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
AAVVDTYRDVVYLNEQAKELGLVRDRQLDDQAWRAAQQALGGDDVEFDLLPGKRPAAGRS
HHHHHHHHHHEEECHHHHHHCCHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCC
GLSVHGHARLLSEKDRRFAVVFVHDQSDYVRMEAARRDFVANVSHELKTPVGAMALLAEA
CCEECHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LLASADDAETVSRFAEKVLIEANRLGYMVAELIELSRLQGAERLPNVTDIDVDIIVSEAI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHH
ARHKVAADTAAIEVRTDPPSGLRVLGDQTLLVTALANLVSNAIAYSPGGSLVSISRRRRG
HHHHHHCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHEECCCCCEEEEHHHCCC
DNIEIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHNGSIGV
CCEEEEEECCCCEEEECCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCEEE
WSKPGTGSTFTLSIPAAMPLYQDNDEQSGQPRGCDMWLNRPQREEEEFKSMTPAQAMMQS
ECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHCCCHHHHHHHH
EVTRGNVNDKCPDCGGRGIAG
HHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]