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The map label for this gene is regX3 [H]

Identifier: 221230794

GI number: 221230794

Start: 2914387

End: 2914983

Strand: Reverse

Name: regX3 [H]

Synonym: MLBr_02439

Alternate gene names: 221230794

Gene position: 2914983-2914387 (Counterclockwise)

Preceding gene: 221230795

Following gene: 221230792

Centisome position: 89.2

GC content: 60.13

Gene sequence:

>597_bases
GTGGTGACCGATGGGCCAGCGGCACTAGCGGAGTTCGATCGCTCCGGGGCGGACATCGTGCTGCTGGACTTGATGCTGCC
GGGGATGTCTGGCACTGATGTGTATAAGCAGCTGCGTGTTCGTTCCAGTGTGCCGGTGATCATGGTGACTGCTCGAGACA
GTGAGATTGACAAAGTGGTCGGCCTCGAGCTGGGCGCCGACGACTATGTTACGAAACCCTATTCGGCGCGTGAATTGATC
GCCCGGATCCGGGCGGTGCTGCGGCGTGGCGGTGATGACGACTCCGAAATTAGCGATGGTGTGCTGGAGTCCGGGCCGCT
CCGGATGGATGTTGAGCGGCATGTGGTCTCGGTGAACGGCTATGCCATCACCCTGCCTCTTAAGGAATTCGATCTGCTGG
AGTACCTGATGCGCAATAGCGGGCGGGTGCTAACCCGAGGGCAGCTGATTGACCGGGTCTGGGGTGTGGATTACGTCGGC
GATACCAAGACCCTCGATGTCCACGTCAAGCGGCTGCGCTCCAAGATCGAGGCCGATCCCGCTAACCCGGTACATCTGGT
GACAGTGCGAGGTCTGGGCTACAAACTGGAGAGTTAG

Upstream 100 bases:

>100_bases
GAGAGGGAATGTGAATGATAAGTGTCCTGATTGTGGAGGACGAGGAATCGCTGGCTGATCCACTGGCGTTTCTCCTCCGC
AAGGAGGTTTTGAGCCCACG

Downstream 100 bases:

>100_bases
CCTGTGCACCGCACTGTGACCACCTCGTCAGCCACAGCCAGCGTCATGATCGATAGCTGCGGTTCACCTCTAGGCATCAC
GGGTGCGCTCAATCTCCACG

Product: putative two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MVTDGPAALAEFDRSGADIVLLDLMLPGMSGTDVYKQLRVRSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELI
ARIRAVLRRGGDDDSEISDGVLESGPLRMDVERHVVSVNGYAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGVDYVG
DTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLES

Sequences:

>Translated_198_residues
MVTDGPAALAEFDRSGADIVLLDLMLPGMSGTDVYKQLRVRSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELI
ARIRAVLRRGGDDDSEISDGVLESGPLRMDVERHVVSVNGYAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGVDYVG
DTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLES
>Mature_198_residues
MVTDGPAALAEFDRSGADIVLLDLMLPGMSGTDVYKQLRVRSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELI
ARIRAVLRRGGDDDSEISDGVLESGPLRMDVERHVVSVNGYAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGVDYVG
DTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLES

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=195, Percent_Identity=40.5128205128205, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1786599, Length=196, Percent_Identity=40.8163265306122, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788394, Length=198, Percent_Identity=38.3838383838384, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1786784, Length=181, Percent_Identity=41.9889502762431, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1789809, Length=185, Percent_Identity=38.3783783783784, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786911, Length=179, Percent_Identity=38.5474860335196, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1789402, Length=181, Percent_Identity=39.7790055248619, Blast_Score=120, Evalue=4e-29,
Organism=Escherichia coli, GI1790860, Length=180, Percent_Identity=37.7777777777778, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1790863, Length=203, Percent_Identity=32.0197044334975, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI2367329, Length=175, Percent_Identity=38.8571428571429, Blast_Score=116, Evalue=9e-28,
Organism=Escherichia coli, GI1787375, Length=181, Percent_Identity=37.0165745856354, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1787229, Length=203, Percent_Identity=36.9458128078818, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1790552, Length=196, Percent_Identity=35.7142857142857, Blast_Score=106, Evalue=8e-25,
Organism=Escherichia coli, GI145693140, Length=189, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=1e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 21851; Mature: 21851

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTDGPAALAEFDRSGADIVLLDLMLPGMSGTDVYKQLRVRSSVPVIMVTARDSEIDKVV
CCCCCHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHEE
GLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEISDGVLESGPLRMDVERHVVSVNG
EEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEEHEEEEECC
YAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGVDYVGDTKTLDVHVKRLRSKIEADP
EEEEEECHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
ANPVHLVTVRGLGYKLES
CCCEEEEEEECCCEEECC
>Mature Secondary Structure
MVTDGPAALAEFDRSGADIVLLDLMLPGMSGTDVYKQLRVRSSVPVIMVTARDSEIDKVV
CCCCCHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHEE
GLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEISDGVLESGPLRMDVERHVVSVNG
EEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEEHEEEEECC
YAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGVDYVGDTKTLDVHVKRLRSKIEADP
EEEEEECHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
ANPVHLVTVRGLGYKLES
CCCEEEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA